Lyophilization Articles & Reports
?-Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization, and Dissolution Studies?-Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization, and Dissolution Studies
March 2004
M. Narender Reddy, Tasneem Rehana, S. Ramakrishna, K. P. R. Chowdary, and Prakash V. D
?-Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization, and...
A case for the streamlined procedureA case for the streamlined procedure
Julian Hitchcock
21 March 2005
Mills & Reeve
A recent swift conclusion to a patent claim in the Court of Appeal could herald more patent litigation in the UK,
http://www.cambridgenetwork.co.uk/POOLED/ARTICLES/...
A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndromeA randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndrome
April 2003
H. J. Kim, M. Camilleri, S. Mckinzie, M. B. Lempke, D. D
A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms...
A Review of mouth dissolving tablet technologiesA Review of mouth dissolving tablet technologies
Gothoskar, A.V.
11/1/2003
Pharmaceutical Technology
In addition to successfully delivering a drug to the body, the goal of any drug delivery syste
http://www.highbeam.com/library/doc0.asp...
A Shot at a New Drug-Delivery SystemA Shot at a New Drug-Delivery System
By: David Pescovitz
May 2003
Berkeley Engineering Lab Notes
Tomorrow's rural populations may be saved from deadly diseases like malaria, typhoid, and whoopin
http://www.coe.berkeley.edu/labnotes/0503/liepmann...
ACAMBIS PLC - AcquisitionACAMBIS PLC - Acquisition
5/10/2005
PR Newswire UK Disclose
Acambis expands manufacturing capability with acquisition of US-based fill/
finish facility
Cambridge, UK and Cambridge, Massachuset
http://www.highbeam.com/library/doc0.asp...
Allergen ImmunotherapyAllergen Immunotherapy
August 15, 2004
JENNIFER L. HUGGINS, M.D., and R. JOHN LOONEY, M.D.
American Academy of Family Physicians
Allergen immunotherapy (also called allergy vaccine therapy) involv
http://www.aafp.org/afp/20040815/689.html
American Association of Tissue BanksAmerican Association of Tissue Banks
1320 Old Chain Bridge Rd., Suite 450, McLean, Virginia 22101.
The American Association of Tissue Banks (AATB) is a scientific, not-for-profit, peer group organ
http://www.aatb.org/
Analysis on ultrastructure of lyophilized red blood cellsAnalysis on ultrastructure of lyophilized red blood cells
April 1, 2003
Zhongguo Shi Yan Xue Ye Xue Za Zhi
Medline Abstract
HighWire Press
Institute of Transfusion Medicine, Academy of Military
http://highwire.stanford.edu/cgi/medline/pmid;1274...
Antidiabetic effect of diasulin, a herbal drug, on blood glucose, plasma insulin and hepatic enzymes of glucose metabolism in hyperglycaemic ratsAntidiabetic effect of diasulin, a herbal drug, on blood glucose, plasma insulin and hepatic enzymes of glucose metabolism in hyperglycaemic rats
July 2004
L. Pari and R. Saravanan, Department of Bi
Antidiabetic effect of diasulin, a herbal drug, on blood glucose, plasma insulin...
Aseptic formulation and filling using isolator technologyAseptic formulation and filling using isolator technology
Akers, James
8/1/2003
Pharmaceutical Technology;
Isolator technology can be used in clinical product formulation and filling facilities t
http://www.highbeam.com/library/doc0.asp...
Aseptic Vial and Syringe FillingAseptic Vial and Syringe Filling
Narlin B. Beaty, Ph.D.
Sublimation Science LLC
Like the preparation of a fine dinner, aseptic filling of vials and syringes is best performed with the highest quali
http://www.sublimationscience.com/myCode/Publicati...
Assure Batch Uniformity for Freeze-Dried ProductsAssure Batch Uniformity for Freeze-Dried Products
March 2005
By Edward H. Trappler, President, Lyophilization Technology
PharmaManufacturing.com
Success requires precise control of process condit
http://www.pharmamanufacturing.com/ME2/dirmod.asp....
Avant, Harvard to develop cholera vaccineAvant, Harvard to develop cholera vaccine
July 18, 2005
By Steve Mitchell
United Press International
World Peace Herald
WASHINGTON -- The National Institutes of Health has awarded nearly $500,0
http://www.wpherald.com/storyview.php...
Azacitidine: A novel agent for myelodysplastic syndromes14 Christman JK, Mendelsohn N, Herzog D et al. Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60). Cancer Res. 1983; 43:763Ã’9.
15 Creusot F,
http://www.ajhp.org/cgi/content/full/62/15/1567...
Bacterial ghosts as antigen delivery vehiclesBacterial ghosts as antigen delivery vehicles
Received 31 January 2004; accepted 25 January 2005. Available online 20 April 2005.
Ulrike Beate Mayra, Petra Walchera, Chakameh Azimpoura, Eva Ried
http://www.sciencedirect.com/science...
Baxter expands lyophilisation capacity
Baxter expands lyophilisation capacity
12/07/2006
by Emilie Reymond
in-Pharmatechnologist.com
Baxter is expanding its lyophilisation capacity at its German facility to support future growth of i
http://www.in-pharmatechnologist.com/news/ng.asp.....
Baxter Tackles Insoluble SolutionsBaxter Tackles Insoluble Solutions
April/May 2004
Agnes Shanley, Editor in Chief
Pharmaceutical Manufacting
After less than three years in the contract manufacturing business, Baxter Pharmaceutica
http://www.pharmamanufacturing.com/ME2/dirmod.asp....
Beacon Pharma gets going by Jan nextBeacon Pharma gets going by Jan next
7/15/2005
Financial Express
Beacon Pharmaceuticals Ltd, a Tk 1.30 billion plant designed to produce high-tech anti-cancer medicines, will start operation b
http://www.financialexpress-bd.com/index3.asp...
Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, and dissolution studiesBeta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, and dissolution studies
By: Reddy MN, Rehana T, Ramakrishna S, Chowdhary KP, Diwan PV. - Pharmacology Division, Indian
Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, ...
Biological Vial: More than Just a Pretty PackageBiological Vial: More than Just a Pretty Package
February 1, 2005
No Author Listed
Pharmaceutical Executive
Biological products, derived from proteins, peptides, and enzymes, constitute a rapidly
http://www.pharmexec.com/pharmexec/article/article...
Biological Vial: More than Just a Pretty PackageWhat are manufacturers' main concerns for packaging? They want components that operate well with their filling lines and their full range of processing. If every time they run 1,000 stoppers down the
http://www.pharmexec.com/pharmexec/article/article...
Biotech potato provides hepatitis vaccineBiotech potato provides hepatitis vaccine
MIKE TONER
2/15/2005
The Atlanta Journal and Constitution
Researchers reported Monday that potatoes genetically modified to carry a vaccine against hepati
http://www.highbeam.com/library/doc0.asp...
BIOTERRORISM: Anthrax Powder: State of the Art?BIOTERRORISM: Anthrax Powder: State of the Art?
Matsumoto, Gary
11/28/2003
Science
Although the investigation seems focused on the idea that the anthrax powder contained in the letters sent to th
http://www.highbeam.com/library/doc0.asp...
BOC Edwards Pharmaceutical Systems Signs ?7m DealBOC Edwards Pharmaceutical Systems Signs ?7m Deal
July 6, 2005
Process Control Today
BOC Edwards Pharmaceutical Systems has signed a ?7m deal to supply a combination of its engineered-to-order load
http://www.pandct.com/media/shownews.asp...
Brazil opens microbe bank for bioprospectorsBrazil opens microbe bank for bioprospectors
14 March 2005
Wagner de Oliveira
SciDevNet
[RIO DE JANEIRO] Hundreds of bacteria, fungi and yeast species, mostly collected from the wilds of Brazil, h
http://www.scidev.net/news/index.cfm...
Brochure: AdVantage Benchtop Freeze DryersBrochure: AdVantage Benchtop Freeze Dryers
05/19/2005
Published By: VirTis -- an SP Industries Company
This new VirTis? AdVantage? Benchtop Freezer brochure from SP Industries focuses on the adv
http://www.laboratorynetwork.com/Downloads/Detail....
Brochure: EZ-CFU?Brochure: EZ-CFU?
11/30/2004
Published By: MicroBiologics, Inc.
EZ-CFU? One Step, from MicroBioLogics Inc., is made to support growth promotion microorganism challenges that must meet USP/EP/JP
http://www.laboratorynetwork.com/Downloads/Detail....
Camptothecin-catalyzed phospholipid hydrolysis in liposomesCamptothecin-catalyzed phospholipid hydrolysis in liposomes
January 2005
Ann Mari S?tern, Merete Skar, ?smund Braaten and Martin Brandl
International Journal of Pharmaceutics, Volume 288, Issue 1,
http://www.sciencedirect.com/science...
Caprolactonic poloxamer analog: PEG-PCL-PEG.Caprolactonic poloxamer analog: PEG-PCL-PEG.
March-April 2005
Hwang MJ, Suh JM, Bae YH, Kim SW, Jeong B.
Biomacromolecules. 2005 Mar-Apr;6(2):885-90.
PubMed
You can view the abstract online. A s
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
Cardinal Health-Pharmaceutical DevelopmentCardinal Health-Pharmaceutical Development
8/1/2003
Pharmaceutical Technology
Cardinal Health's Zydis technology produces a freeze-dried wafer heralded for its effectiveness for anti-inflammatory
http://www.highbeam.com/library/doc0.asp...
Center works to bring life to that which is ?dead?Blood banks show interest
The No. 1 clinical problem with transfusion of platelets from blood banks is septic shock, caused by bacterial contamination, Tablin said. It's a particular problem for U.S
http://www.dateline.ucdavis.edu/dl_detail.lasso...
Clinical results of OK-432 injection therapy for ganglions.Clinical results of OK-432 injection therapy for ganglions.
April 2005
Taniguchi T, Motomura H, Ohba N, Harada T, Muraoka M, Ishii M., Department of Plastic and Reconstructive Surgery, Osaka City Un
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
CMOs Attack Biomanufacturing MarketVetter Broadens Capabilities
Another major player in the European contract manufacturing arena has announced expansion plans, this time for the fill-and-finish (sterile injectable manufacturing) seg
http://www.ptemag.com/pharmtecheurope/article/arti...
Continuous Processing in Pharmaceutical ManufacturingContinuous Processing in Pharmaceutical Manufacturing
Matthew J. Mollan Jr., Ph.D. and Mayur Lodaya, Ph.D., Pfizer Inc.
1.0 Introduction
Pharmaceutical processing in the manufacturing environment
http://www.americanpharmaceuticalreview.com/articl...
Control of Japanese encephalitis in India: A realityControl of Japanese encephalitis in India: A reality
2004
Kabilan Lalitha
The Indian Journal of Pediatrics
? Abstract
Japanese encephalitis is considered as a serious disease due to the compl
http://www.ijppediatricsindia.org/article.asp...
Coolers provide continuous cooling as low as -45 CCoolers provide continuous cooling as low as -45 C
3/1/2005
Laboratory Equipment
The KR Series Coolers offers four low-temperature units that can be used to achieve low temperature capability with
http://www.highbeam.com/library/doc0.asp...
Coolers provide continuous cooling as low as -45 CCoolers provide continuous cooling as low as -45 C
3/1/2005
Laboratory Equipment
The KR Series Coolers offers four low-temperature units that can be used to achieve low temperature capability with
http://www.highbeam.com/library/doc0.asp...
Cryopreservation of adherent human embryonic stem cellsCryopreservation of adherent human embryonic stem cells
14 Oct 2004
Received: 18 December 2003; Accepted: 16 June 2004
Lin Ji, Juan J. de Pablo, Sean P. Palecek *
Biotechnology and Bioengineering
http://www3.interscience.wiley.com/cgi-bin/abstrac...
Cutting costs in contamination controlCutting costs in contamination control
30/09/2004
in-pharmatechnologist.com
One of the consequences of the new pharmaceutical legislation that came in last year is that companies involved in the ma
http://www.in-pharmatechnologist.com/news/ng.asp.....
Datasheet: Sample Taking DeviceDatasheet: Sample Taking Device
06/13/2005
Published By: Bolz-Summix, A Division of MPE Group, Inc.
Bolz-Summix has developed a sample taking device that will work for sampling powders or liquids
http://www.laboratorynetwork.com/Downloads/Detail....
Deep FreezeDeep Freeze
August/September 2003
By Narlin B. Beaty, PhD
PharmaQuality
If Mr. Freeze had current lyophilization processes at his disposal, he might have triumphed over Batman. Fortunately, ph
http://www.pharmaquality.com/Feature2.htm
Directory of lyphilization service providersDirectory of lyphilization service providers
2/1/2004
Pharmaceutical Technology
Directory of lyophilization services providers.
Prelyophilization Lyophiliz
http://www.highbeam.com/library/doc0.asp...
Discussion of Lyophilization or Freeze Drying in TraysDiscussion of Lyophilization or Freeze Drying in Trays
Thomas A. Jennings, Ph.D and Professor Ana Bacaoanu, Ph.D?.
May 2003
INSIGHT
No doubt that trays played a major role in the early days of lyo
http://www.phase-technologies.com/html/vol._6_no._...
Distribution of liposome-encapsulated antimony in dogsDistribution of liposome-encapsulated antimony in dogs
February 2003
D.A. Schettini1, A.P. Costa Val3, L.F. Souza2, C. Demicheli4, O.G.F. Rocha5, M.N. Melo2, M.S.M. Michalick2 and F. Fr?zard1
Depar
http://www.scielo.br/scielo.php...
DRAXIS Manufacturing Facilities Pass Extensive FDA Inspection
DRAXIS Manufacturing Facilities Pass Extensive FDA Inspection
May 30 2007
Industry Canada:Pharmaceuticals
DRAXIS Health Inc. (Mississagua) has received notification from the US Food and Drug Admi
http://strategis.ic.gc.ca/epic/site/p-pp.nsf/en/h_...
Drying in Pharmaceutical and Biotechnological IndustriesDrying in Pharmaceutical and Biotechnological Industries
2003
SAGE Publications
M. Guerrero
Ferrer International S.A., R&D Center, Juan de Sada 32 08028 Barcelona, Spain mguerrero-research@ferrer
http://fst.sagepub.com/cgi/content/abstract/9/3/23...
Dutch scheme extends helping hand to biotech SMEsDutch scheme extends helping hand to biotech SMEs
02/03/2005
NOVIS
The Netherlands has set up a programme to boost its biotechnology sector by helping small and medium-sized biopharma firms to de
http://www.in-pharmatechnologist.com/news/ng.asp.....
Eliminating the freeze-dry bottleneckEliminating the freeze-dry bottleneck
9 April 2003
Laboratory Talk
CryoDry is an extension of Ilmvac's existing laboratory and production freeze drying business, which encompasses drying in flasks,
http://www.laboratorytalk.com/news/ilm/ilm111.html
Engineered unit enters new market with $20 mln dealEngineered unit enters new market with $20 mln deal
St. Louis Business Journal
July 15, 2005
Engineered Support Systems' Inc.'s Radian Inc. has been reinforcing U.S. Army trucks against roadside bo
http://stlouis.bizjournals.com/stlouis/stories/200...
Enron - A Lesson for LyophilizationEnron - A Lesson for Lyophilization
Fall 2003
Thomas A. Jennings, Ph.D.
Phase Technologies, Inc.
APR
On September 11, 2001 the United States experienced a disaster unparalleled in our history. T
http://www.americanpharmaceuticalreview.com/articl...
Eudragit S100 Entrapped Insulin Microspheres for Oral DeliveryEudragit S100 Entrapped Insulin Microspheres for Oral Delivery
January 21, 2005
Deepti Jain1, A.K.Panda2 and D.K. Majumdar1
1Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences
http://www.aapspharmscitech.org/prepub/Documents/A...
Evidence of Risk for H2N2 1957 Pandemic FluEvidence of Risk for H2N2 1957 Pandemic Flu
April 18, 2005
Commentary
Recombinomics
>> Even if a sample included in a test kit is a strain of a deadly virus, the sample is not necessarily dangero
http://www.recombinomics.com/News/04180504/H2N2_Ri...
Excipients overcome virus formulation challengeExcipients overcome virus formulation challenge
13/07/2004
in-pharmatechnologist.com
Viruses are increasingly being used as delivery vectors in the pharmaceutical industry, for example to deliver g
http://www.in-pharmatechnologist.com/news/ng.asp.....
Fast, flexible freeze drying at the lab benchFast, flexible freeze drying at the lab bench
May 16, 2005
Laboratorytalk
Range of condenser temperature options provides all the drying power required to freeze dry aqueous and most organic-based
http://www.laboratorytalk.com/news/bop/bop109.html
FDA Approvals: Retisert, WinRho SDF, IMx Sirolimus AssayFDA Approvals: Retisert, WinRho SDF, IMx Sirolimus Assay
April 28, 2005
Yael Waknine
Medscape
The U.S. Food and Drug Administration (FDA) has approved an orphan drug indication for fluocinolone ac
http://www.medscape.com/viewarticle/504004
FDA Approves New Paclitaxel FormulationFDA Approves New Paclitaxel Formulation
10 January 2005
Cheryl A. Thompson
American Society of Health-System Pharmacists
BETHESDA, MD, 10 January 2005 ? Abraxane, a formulation of paclitaxel that
http://www.ashp.org/news/ShowArticle.cfm...
FDA Sends Warning Letter to Merck and Company, Inc.Please clarify the steps that your firm will take toward modernizing your specification/characterization procedures and practices. Currently, you have produced [redacted] lots of Asparaginase Intermed
http://www.medadnews.com/News/Index.cfm...
Fill 'Em UpFill 'Em Up
January 2004
By Angelo De Palma, Ph.D., Contributing Editor
PharmaManufacturing.com
Because pharmaceutical filling bridges the huge gap between bulk manufacture and distribution, ever
http://www.pharmamanufacturing.com/ME2/dirmod.asp....
First West Coast baby born using frozen egg techniqueFirst West Coast baby born using frozen egg technique
7/10/2003
Bio.com
The University Fertility Consultants at the Oregon Health & Science University have successfully frozen human eggs that have
http://www.bio.com/newsfeatures/newsfeatures_resea...
Forced Degradation of PharmaceuticalsMass Balance
Assessments of bass balance in degradation studies checks to see if the amount of material detected in a stressed sample matches the amount present before stress was applied. The assay f
http://www.americanpharmaceuticalreview.com/articl...
Freeze Dryers: space saving designFreeze Dryers: space saving design
10/1/2003
Pharmaceutical Processing
LYOVAC[R] freeze-drying systems feature a space-saving design that allows for flexible integration into a pharmaceutical proc
http://www.highbeam.com/library/doc0.asp...
Freeze Drying 101Freeze Drying 101
Some helpful freeze drying basics
by Larry Ulfik
VirTis
After you finish our Lyophilization 101 notes, you may want to attend our Fundamentals of Lyophilization Seminar. Full det
http://www.virtis.com/literature/freeze101.jsp
Freeze drying system: for research and process developmentFreeze drying system: for research and process development
10/1/2003
Pharmaceutical Processing
The LyoStar II features an enhanced cascade refrigeration system that has more horsepower to provide
http://www.highbeam.com/library/doc0.asp...
Freeze drying systems: www.SPindustries.comFreeze drying systems: www.SPindustries.com
5/1/2005
Pharmaceutical Processing
Hull freeze drying systems (lyophilizers) are engineered to pharmaceutical cGMP standards. Hull provides project sup
http://www.highbeam.com/library/doc0.asp...
Freeze drying with extra flexibilityFreeze drying with extra flexibility
15 July 2005
Laboratory talk
Freeze dryer has been engineered to handle all applications from phase one research to production clinical trial batches
Note: A f
http://www.laboratorytalk.com/news/bop/bop111.html
Freeze-Dryers ? Particle Monitoring Requirements, 2003Freeze-Dryers ? Particle Monitoring Requirements, 2003
19-Dec-03
Mark Hallworth
Pharmaceutical Business Manager
Particle Measuring Systems
Introduction
Freeze-drying is used to produce the major
http://www.pmeasuring.com/particleCounting/appNote...
Freeze-Drying ? an Art or a Science?Although techniques for the study of Tg? are well established, there has been little commercially available equipment for the study of Tc itself until the launch of the BTL ?Lyostat? freeze-drying mic
http://www.lyophilizationtechnology.com/freezeart....
Freeze-drying capabilitiesFreeze-drying capabilities
Dec, 2004
Pharmaceutical Technology
Lyophilization Technology offers capabilities for highly potent compounds, oncology therapeutics, and biologicals requiring BL2 cont
http://www.findarticles.com/p/articles/mi_m0EEH/is...
Freeze-drying firm warms to Maryland's biotech zoneFreeze-drying firm warms to Maryland's biotech zone
May 20, 2005
Neil Adler
American City Business Journals, Inc.
After scouting space throughout the mid-Atlantic region, Israel-based Core Dynam
http://washington.bizjournals.com/washington/stori...
Freeze-drying for IVDsFreeze-drying for IVDs
Originally Published IVD Technology June 2004
medical devicelink
Advances in automation have imparted greater control over the lyophilization process.
For reagents that are
http://www.devicelink.com/ivdt/archive/04/06/009.h...
Freeze-drying for IVDsFreeze-drying for IVDs
Originally Published IVD Technology June 2004
medical devicelink
Advances in automation have imparted greater control over the lyophilization process.
For reagents that are
http://www.devicelink.com/ivdt/archive/04/06/009.h...
Freeze-drying of silymarin-loaded solid lipid nanoparticlesFreeze-drying of silymarin-loaded solid lipid nanoparticles
J He, JF Feng, LL Zhang, WG Lu, and SX Hou
January 1, 2005
HighWire Press
OBJECTIVE: To investigate lyophilization of SM-SLN. METHOD: Th
http://highwire.stanford.edu/cgi/medline/pmid;1571...
Freeze-drying servicesFreeze-drying services
5/1/2005
Medical Device Technology
Lyofal specialises in lyophilisation, a technique of natural drying under cold and vacuum conditions. The company owns 25 freeze driers of
http://www.highbeam.com/library/doc0.asp...
FreeZone Stoppering Tray DryerFreeZone Stoppering Tray Dryer
3/1/2005
R & D
The Labconco FreeZone Stoppering Tray Dryer for use with Labconco FreeZone 6-, 12-, and 18-L Freeze Dry Systems, has three shelves for batch or bulk
http://www.highbeam.com/library/doc0.asp...
Future imperfect for Quintiles?Future imperfect for Quintiles?
Miller, Jim
3/1/2003
Pharmaceutical Technology Europe
Following the rejection of Dennis Gillings' offer to buy back Quintiles, the company is looking at alternativ
http://www.highbeam.com/library/doc0.asp...
Gamma Sterilization of PharmaceuticalsGamma Sterilization of Pharmaceuticals
May 2004
By Ruth Garcia, Betty Howard, Rose LaRue, Glenn Parton, and John WalkerSteris Isomedix Services (Mentor, OH)
Sterility is desirable not only for medi
http://www.steris.com/isomedix/PDF/Pharma_pmpn_May...
Gastric and Duodenal Antiulcer Effects of Rhizophora mangleGastric and Duodenal Antiulcer Effects of Rhizophora mangle
May 2004
Luz Mar?a S?nchez Perera , Niurka Yasmin Batista, A. Rodr?guez, F. Farrada, C. Bulnes
Pharmaceutical Biology (Formerly Internat
http://journalsonline.tandf.co.uk/app/home/contrib...
Gastroretentive Delivery Systems: Hollow BeadsGastroretentive Delivery Systems: Hollow Beads
2004
R. Talukder and R. Fassihi
Drug Development and Industrial Pharmacy Volume 30, Number 4 / 2004
You can view the abstract online. A subscripti
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
Genevac speeds up lab-scale freeze-dryingGenevac speeds up lab-scale freeze-drying
16/05/2005
NOVIS
16/05/2005 - Genevac has introduced new technology for its Model HT-4X centrifugal evaporator whereby the system can be used to accelerat
http://www.drugresearcher.com/productnews/news.asp...
Grants Given for Freeze-Dried Vaccine, Nutritious TuberGrants Given for Freeze-Dried Vaccine, Nutritious Tuber
29 June 2005
by: Marilyn Chase
The Truth about Trade and Technology
A program to conquer health problems of the poor is awarding rich gra
http://www.truthabouttrade.org/article.asp...
Growth hormone therapy.Growth hormone therapy.
February 2005
Bajpai Anurag1, Menon P SN2
1 Division of Pediatric Endocrinology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
2 Depar
http://www.ijppediatricsindia.org/article.asp...
GSK invests in vaccine factory
GSK invests in vaccine factory
Sep 30 2006
By The Journal
Drugs firm GlaxoSmithKline is investing more than ?339m into a French factory to boost vaccine manufacturing capacity.
The pharmaceutica
http://icnewcastle.icnetwork.co.uk/0500business/bu...
Guidance for Industry on Drug SubstanceGuidance for Industry on Drug Substance
INTRODUCTION
Information on the chemistry, manufacturing, and controls (CMC) for the drug substance must be submitted to support the approval of original new
http://www.fda.gov/OHRMS/DOCKETS/98fr/2003d-0571-g...
GUIDE TO INSPECTIONS OF LYOPHILIZATIONGUIDE TO INSPECTIONS OF
LYOPHILIZATION OF PARENTERALS
July, 1993
Introduction
Lyophilization or freeze drying is a process in which water is removed from a product after it is frozen and placed un
http://bcg-usa.com/docs/1993/FDA199307B.pdf
Healing power of age-old therapyTCM as an art
Dr Chang does agree that TCM needs to be modernized.
But its modernization should put more emphasis on improving prescription preparation with the help of modern science, he suggeste
http://news.xinhuanet.com/english/2005-09/21/conte...
Heat Stability of the Lyophilized Sabin PoliovaccineHeat Stability of the Lyophilized Sabin Poliovaccine
Received February 26, 2003. Accepted May 1, 2003
Hiroshi Shiomi, Tomoko Urasawa*1 and Shozo Urasawa*
Japanese Journal of Infectious Diseases
De
http://www.nih.go.jp/JJID/56/70.html
High-Throughput Purification of Single Compounds and LibrariesHigh-Throughput Purification of Single Compounds and Libraries
By: Mathias Schaffrath, Erich von Roedern,* Peter Hamley, and Hans Ulrich Stilz - Chemistry, Aventis Pharma Deutschland GmbH, a Compan
http://pubs.acs.org/cgi-bin/abstract.cgi/jcchff/as...
HollisterStier to add second freeze-drying system in SpokaneHollisterStier to add second freeze-drying system in Spokane
Jun 2, 2005
by Tom Sowa
Spokesman Review, The (Spokane)
HollisterStier Laboratories LLC, one of Spokane's most successful manufactur
http://www.findarticles.com/p/articles/mi_qn4186/i...
How to Evaluate a Publication on Lyophilization/Freeze DryingHow to Evaluate a Publication on Lyophilization/Freeze Drying
August 2003
Insight
For those of us who are experienced in this field, and perhaps already have a well established view on the subject,
http://www.phase-technologies.com/html/vol._6_no._...
How to freeze mamalian cellsHow to freeze mamalian cells
June 29, 2004
The Science Advisory Board
Description
This protocol describes how to freeze tissue culture cells (mamalian) in a way that they will be viable when thaw
http://www.scienceboard.net/resources/protocols.as...
Humidity Considerations For Cold Shelf LoadingHumidity Considerations For Cold Shelf Loading
3/2/2005
VertMarkets, Inc.
It is common practice during the production of a parenteral drug which is to eventually be freeze dried for the solution
http://www.laboratorynetwork.com/content/news/arti...
Hyaluron to Expand its Burlington, Massachusetts Facility
Hyaluron to Expand its Burlington, Massachusetts Facility
2/14/2007
Expansion Management
BURLINGTON, Mass. (February 14, 2007) ? The company will receive a $1 million low interest loan to expand
http://www.expansionmanagement.com/smo/articleview...
Impressive performance from virtual freeze dryerImpressive performance from virtual freeze dryer
News from: Biopharma Process Systems
Edited by: Processingtalk Editorial Team on 7 July 2003
The latest addition to the VirTis freeze dryer range is
http://www.processingtalk.com/news/bop/bop102.html
Improving Vaccine Stability, Potency, and DeliveryEarly input of formulation research is important since it may significantly reduce product development cycle times by avoiding the selection of labile candidates and screening out potential bad actors
http://www.americanpharmaceuticalreview.com/articl...
Injecting Excitement into Parenteral Drug PackagingInjecting Excitement into Parenteral Drug Packaging
April 2005
Jenevieve Blair Polin, Contributing Editor
Medical DeviceLink
Packaging for injectable parenteral drugs is changing its form and fu
http://www.devicelink.com/pmpn/archive/05/04/003.h...
Inulin could be new protein stabiliserInulin could be new protein stabiliser
03/02/2004
Drug Researcher.com
The widely used food ingredient inulin could be a more effective alternative to established excipients in stabilising protein-
http://www.drugresearcher.com/news/ng.asp...
Is Lyophilization Deceptive and Devious at Times?Is Lyophilization Deceptive and Devious at Times?
Thomas A. Jennings, Ph.D.
December 2003
INSIGHT
Recently I was in correspondence with a colleague whom I respect a great deal. I share with them m
http://www.phase-technologies.com/html/vol._6_no._...
Just a spoonful of sugarJust a spoonful of sugar
April 2005
Chemistry World
In short
Thermostable vaccines can be made by spray drying a mixture of vaccine and sugars in hot air, resulting in vaccines encased in sugar-gl
http://www.rsc.org/chemistryworld/features/free/CW...
Lab-scale freeze-drier from BuchiLab-scale freeze-drier from Buchi
09/03/2004
DrugResearcher.com
Switzerland?s Buchi has launched a small-scale oven for freeze-drying samples that puts the technology within reach of laboratories
http://www.drugresearcher.com/news/ng.asp...
Lab-scale freeze-drier launched in UKLab-scale freeze-drier launched in UK
6/23/05
LabTechnologist.com
The Compaclyo range is aimed at product R&D, manufacture of clinical trial materials and small production batches, according to BP
http://www.labtechnologist.com/news/news-ng.asp...
Laboratoire Valmont has appliedLaboratoire Valmont has applied
1/1/2003
Household & Personal Products Industry
Laboratoire Valmont has applied its state-of-the-art technology, lyophilization, to its HP DNA active for the compan
http://www.highbeam.com/library/doc0.asp...
Large-scale production of lipoplexes with long shelf-lifeLarge-scale production of lipoplexes with long shelf-life
Jule Clementa, 1, , , Karin Kiefera, 1, Andrea Kimpflera, Patrick Garidelb and Regine Peschka-S?ss
January 2005
European Journal of Pharmac
http://www.sciencedirect.com/science...
Leachables Found in Parenteral Drug ProductsLeachables Found in Parenteral Drug Products
March/April 2004
Jim Castner, Ph.D., Neal Williams, M.S. and Michael Bresnick, M.A.
Bristol Myers Squibb Medical Imaging
APR
Introduction
In the pr
http://www.americanpharmaceuticalreview.com/articl...
Liquid nitrogen technology benefits freeze-dryersLiquid nitrogen technology benefits freeze-dryers
Edited by: Processingtalk Editorial Team on 5 April 2005
Renowned freeze-drying experts Usifroid, in collaboration with Air Liquide, the world leade
http://www.processingtalk.com/news/bop/bop114.html
Lonza aims to get bigger in peptidesLonza aims to get bigger in peptides
02/05/2005
NOVIS
Lonza is planning a major exansion of its peptides manufacturing capacities at Visp, Switzerland, in response to what it said was ?the increase
http://www.in-pharmatechnologist.com/news/ng.asp.....
Low-Temperature Thermal Analyses are Key to Formulation DesignLow-Temperature Thermal Analyses are Key to Formulation Design
2004
Michael Thomas and Anthony J.Cannon
Pharmaceutical Technology
Product and process development of a lyophilized preparation is a
http://www.pharmtech.com/pharmtech/article/article...
LyoCheck from Thermo speeds up biopharma QCLyoCheck from Thermo speeds up biopharma QC
22/06/2005
in-pharmatechnologist.com
Thermo Electron has launched a new rapid method for the analysis of lyophilised (freeze-dried) materials using ts N
http://www.in-pharmatechnologist.com/news/ng.asp.....
LyophilizationLyophilization
Apri 25, 2004
By Narlin B. Beaty, Ph.D.
Chesapeake Biological Laboratories, Inc.
Please visit the web site to view the article in its entirety.
Elementary lyophilization involves t
http://www.cblinc.com/Assets/Documents/Publication...
Lyophilization is not a freeze-dried technology
Lyophilization is not a freeze-dried technology
01 October 2006
By: Louis Rey, Florence Lhospice
Pharmaceutical Technology Europe
Almost 100 years after its initial development, lyophilizat
http://www.ptemag.com/pharmtecheurope/article/arti...
Lyophilization Made EasyLyophilization Made Easy
March 2003
By
Thomas A. Jennings, Ph.D.
INSIGHT
Vol. 6 No. 3
It was during a planning session for the forthcoming Lyophilization Conference 2003 that will be held in C
http://www.phase-technologies.com/html/vol._6_no._...
Lyophilization of BiopharmaceuticalsLyophilization of Biopharmaceuticals
Not Dated
By: Henry R. Costantino, Nastech /Pharmaceutical Company, Inc.; Michael J. Pikal, University of Connecticut
American Association of Pharmaceutical Sc
http://www.aapspharmaceutica.com/publications/pres...
Lyophilization of polyethylene glycol mixturesLyophilization of polyethylene glycol mixtures
June 2004
By Ketan Amin, Rose-Marie Dannenfelser, Joseph Zielinski, Barbara Wang
Journal of Pharmaceutical Sciences
Please visit the web site to view
http://www3.interscience.wiley.com/cgi-bin/abstrac...
Lyophilization of Unit Dose Pharmaceutical Dosage FormsLyophilization of Unit Dose Pharmaceutical Dosage Forms
May 12, 2003
By P. Thapa; A. J. Baillie; H. N. E. Stevens
Drug Development and Industrial Pharmacy? , Volume 29 , Issue 5
You can vie
http://taylorandfrancis.metapress.com./app/home/co...
Lyophilization of Vaccines: Current TrendsLyophilization of Vaccines: Current Trends
Gerald D. J. Adams
August 2003
Humana Press
Abstract:
Regardless of how effective a vaccine may be in the laboratory, unless the suspension can be sta
http://biomed.humanapress.com/ChapterDetail.pasp.....
Lyophilization Optimization Using DSC and MT-DSCLyophilization Optimization Using DSC and MT-DSC
January/February 2004
A. Rameau, A. Chevalier, and C. Neves
Applied Physics, Pharmaceutical Sciences, Paris Research Center
Aventis Pharma
APR
I
http://www.americanpharmaceuticalreview.com/articl...
Lyophilizer Qualification: Some Practical AdviceLyophilizer Qualification: Some Practical Advice
September/October 2004
Thorsten Fischer, ZLB Behring GmbH (formerly Aventis Behring GmbH), Department Facility Qualification
APR
Key words: Contro
http://www.americanpharmaceuticalreview.com/articl...
Mislabeled H2N2 Virus Leads to Tighter Inventory Control RulesMislabeled H2N2 Virus Leads to Tighter Inventory Control Rules
April 17, 2005
Recombinomics Commentary
>> In response to the problem, the CDC announced this week that the agency would speed up pla
http://www.recombinomics.com/News/04170502/H2N2_In...
NA FEA MED US Polio VaccineNA FEA MED US Polio Vaccine
MARILYNN MARCHIONE, AP Medical Writer
4/10/2005
AP Worldstream
MARILYNN MARCHIONE, AP Medical Writer
AP Worldstream
04-10-2005
Dateline: MILWAUKEE
Dan Wilson r
http://www.highbeam.com/library/doc0.asp...
Nanotechnology delivers military powerNanotechnology delivers military power
May 2005
By Ben Ames
Military & Aerospace Electronics
Army leaders are looking for a 21st century battlesuit. The lycra-tight clothing must stop bullets, d
http://mae.pennnet.com/articles/article_display.cf...
Near-infrared spectroscopy as a process analytical toolNear-infrared spectroscopy as a process analytical tool
Bakeev, Katherine A.
9/1/2003
Pharmaceutical Technology Europe
Near-infrared (NIR) spectroscopy has been used for qualitative and quantitat
http://www.highbeam.com/library/doc0.asp...
New Meds Melt in Your MouthNew Meds Melt in Your Mouth
August 6, 2003
By Dwayne Hunter
Betterhumans Staff
Billed as "melt-in-your-mouth" tablets, a new drug-delivery technology is being promoted as an easier, better, cost
http://www.betterhumans.com/Errors/index.aspx...
New Storage Method Amplifies Cells Available for ScienceNew Storage Method Amplifies Cells Available for Science
30 Mar 2004
University of Wisconsin-Madison
newswise
Like many other kinds of cells used in biomedical research, human embryonic stem cells
http://www.newswise.com/articles/view/503929/
New VirTis Shell Bath Offers Efficiency And ConvenienceNew VirTis Shell Bath Offers Efficiency And Convenience
12/2/2004
VertMarkets, Inc.
The new VirTis Benchtop Shell Bath is a self-contained, compact freezing unit designed for the laboratory benc
http://www.laboratorynetwork.com/content/news/arti...
Niro extends drying test centre for pharmaNiro extends drying test centre for pharma
02/03/2005
NOVIS
Denmark-headquartered Niro is finalizing a ?10 million investment programme centred on the expansion of its drying test site, located at
http://www.in-pharmatechnologist.com/news/ng.asp.....
Nonphospholipid Vesicles of Carboplatin for Lung TargetingNonphospholipid Vesicles of Carboplatin for Lung Targeting
Apr-Jun 2003
B. Lu A1, J. Q. Zhang A1, H. Yang A1
Drug Delivery
Taylor & Francis
A1 West China School of Pharmacy, Sichuan Universit
http://taylorandfrancis.metapress.com/app/home/con...
Novel polyester-polysaccharide nanoparticles.Novel polyester-polysaccharide nanoparticles.
2003 Aug
Lemarchand C, Couvreur P, Besnard M, Costantini D, Gref R.
Pharm Res.
Entrez PubMed
UMRCNRS 8612, School of Pharmacy, Chatenay Malabry, Fra
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
Oil-based formulations for oral delivery of insulinOil-based formulations for oral delivery of insulin
September 2004
Chun-Lei Li ; Ying-Jie Deng
Journal of Pharmacy and Pharmacology
DOI: 10.1211/0022357044175
Publisher: Pharmaceutical Press
http://thesius.ingentaconnect.com/vl=7963416/cl=17...
Old Freeze Dryer Repair or Replace?Old Freeze Dryer Repair or Replace?
November 2003
Thomas A. Jennings
Insight
This is a question that in time will certainly arise regarding every freeze dryer when it becomes more than 10 years o
http://www.phase-technologies.com/html/vol._6_no._...
Oral vector vaccines target biothreatsOral vector vaccines target biothreats
Chiarello, Kaylynn
6/1/2004
Pharmaceutical Technology
Since the 2001 terrorist attacks in the United States, U.S. governmental agencies have funded numerous
http://www.highbeam.com/library/doc0.asp...
Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies.Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies.
2004
By Fu Y, Yang S, Jeong SH, Kimura S, Park K.
Critical Review Therapeutic Drug Carrier Syst.
Orally fast disintegrating tablets: developments, technologies, taste-masking an...
Outsourcing OutlookOutsourcing Outlook
March 2003
Jim Miller, PharmSource Information Services, Inc.
Pharmaceutical Technology
Contract research and manufacturing is entering 2003 on a high note with strong fourth-q
http://www.pharmtech.com/pharmtech/data/articlesta...
Overview of Aseptic Fill/Finish ManufacturingOverview of Aseptic Fill/Finish Manufacturing
Douglas Stockdale, President, Stockdale Associates, Inc.
American Pharmaceutical Review
Please visit the web site to view the article in its entirety.
http://www-personal.engin.umich.edu/~lishen/Asepti...
Pace quickens at Hollister-Stier
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December 21, 2006
By Emily Brandler
Spokane Journal of Business
Spokane drug manufacturer Hollister-Stier Laboratories LLC, which has launched a roughly $30 mil
http://www.spokanejournal.com/spokane_id=article&a...
Parenteral contract manufacturingParenteral contract manufacturing
9/1/2003
Pharmaceutical Technology
Baxter Pharmaceutical Solutions is a parenteral contract manufacturer. Services include vial-filling, lyophilization, syringe-fi
http://www.highbeam.com/library/doc0.asp...
Parenteral OutsourcingParenteral Outsourcing
March05
Gil Y. Roth
Contract Pharma
Oral delivery is still the Holy Grail for drug products, but plenty of new drugs (and many more in development) require injection. With s
http://www.contractpharma.com/articles/2005/03/par...
Particle & Device Engineering for Inhalation Drug DeliveryParticle & Device Engineering for Inhalation Drug Delivery
March 2004
Kavitha Koushik and Uday B. Kompella
Drug Delivery Technology
The inhalation route, employed primarily for drugs acting in th
http://www.pharmainfo.net/displayarticle2994.html
Particle designParticle design
Jan, 2005
Pharmaceutical Technology
Hovione offers a brochure that describes its particle design technology and CGMP-compliant spray drying facilities, which have been designed to
http://www.findarticles.com/p/articles/mi_m0EEH/is...
Patheon leads Europe In LyophilizationPatheon leads Europe In Lyophilization
10/28/2003
Pharmaceutical Online
Canada-headquartered contract manufacturing company Patheon is now offering the largest capacity in Europe for Lyophilisati
http://www.pharmaceuticalonline.com/content/news/a...
PennTech dual tray-loader for high outputPennTech dual tray-loader for high output
News from: Biopharma Process Systems
Edited by: Processingtalk Editorial Team on 9 May 2005
The uniquely designed PennTech trayloaders are now available in
http://www.processingtalk.com/news/bop/bop116.html
Pfizer undertakes ?240m expansion at Irish plantPfizer undertakes ?240m expansion at Irish plant
16/09/2004
NOVIS
Rumours of the demise of Ireland as a hotbed of pharmaceutical manufacturing may be premature. Pfizer has just unveiled a plan to s
http://www.in-pharmatechnologist.com/news/ng.asp.....
Pharmaceutical Drying Technology
Pharmaceutical Drying Technology
Richard Taylor & Suling Zhai
Department of Chemical Engineering
University of Cambridge, Cambridge CB2 3RA, UK
Overview
Dry pharmaceutical formulations are re
http://www.cheng.cam.ac.uk/exemplarch2002/sz216/in...
Pharmacokinetics of Paclitaxel-Containing Liposomes in RatsPharmacokinetics of Paclitaxel-Containing Liposomes in Rats
November 2003
Gerald J. Fetterly1,2 and Robert M. Straubinger1
1Department of Pharmaceutical Sciences, University at Buffalo, State Univ
http://www.aapspharmsci.org/articles/ps0504/ps0504...
Pharmacologically active microcarriers: a tool for cell therapyPharmacologically active microcarriers: a tool for cell therapy
June 2005
V.M. Tatard, a, M.C. Venier-Julienne, a, P. Saulnier, a, E. Prechter, a, J.P. Benoit, a, P. Menei, a, b and C.N. Montero-Men
http://www.sciencedirect.com/science...
Post-thaw aging affects activity of lactate dehydrogenasePost-thaw aging affects activity of lactate dehydrogenase
April 2005
Bakul S. Bhatnagar, Sarah J. Nehm, Michael J. Pikal, Robin H. Bogner
Journal of Pharmaceutical Sciences, Volume 94, Issue 6, Dat
http://www3.interscience.wiley.com/cgi-bin/abstrac...
Potato-based vaccine success comes too latePotato-based vaccine success comes too late
April 26, 2005
Andy Coghlan
New Scientist
Genetically engineered potatoes containing a hepatitis B vaccine have successfully boosted immunity in their
http://www.newscientist.com/channel/life/gm-food/d...
Power law equation and liberation kinetics]Power law equation and liberation kinetics]
2005 Jan
Zatloukal Z.
Ceska Slov Farm
[Article in Czech]
Katedra farmaceuticke technologie Farmaceuticke fakulty Univerzity Karlovy, Hradec Kralove. zs
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
Pre-Lyophilized Inspection Machine improves product qualityPre-Lyophilized Inspection Machine improves product quality
3/1/2005
Pharmaceutical Processing
The PLIM performs particle inspection prior to the lyophilization process. It's a camera-based system
http://www.highbeam.com/library/doc0.asp...
Preparation and Structure of Porous Silk Sericin MaterialsPreparation and Structure of Porous Silk Sericin Materials
Published Online: 17 Mar 2005
Received: 21 October 2004; Revised: 4 January 2005; Accepted: 12 January 2005
Wei Tao, Mingzhong Li *, Ruiju
http://www3.interscience.wiley.com/cgi-bin/abstrac...
Preparation, characterization, and stability of liposome-based formulations of mitoxantrone.Preparation, characterization, and stability of liposome-based formulations of mitoxantrone.
January 1, 2005
S Ugwu, A Zhang, M Parmar, B Miller, T Sardone, V Peikov, and I Ahmad
Drug Dev Ind Pharm
Preparation, characterization, and stability of liposome-based formulations of m...
Problems with Thermocouple MeasurementsProblems with Thermocouple Measurements
July 2003
Insight
There are at present two basic temperature transducers used in conjunction with the lyophilization or freeze drying process, i.e., RTD and
http://www.phase-technologies.com/html/vol._6_no._...
Products for tomorrowProducts for tomorrow: how are some medical device companies developing next-generation designs? And how are they bridging the gap between a niche idea and an innovative premium product? In many cases
http://www.highbeam.com/library/doc0.asp...
Rapid QC analysis of lyophilised materialsRapid QC analysis of lyophilised materials
June 22, 2005
Laboratorytalk
Thermo Electron announces the LyoCheck - a rugged, easy-to-use package that provides a rapid method for the analysis of lyoph
http://www.laboratorytalk.com/news/tct/tct118.html
Regents Professor creates vaccines for developing countriesRegents Professor creates vaccines for developing countries
February 13, 2004
Skip Derra
ASU News Releases
Charlie Arntzen has been exploring the use of crops to produce vaccines for 13 years. W
http://www.asu.edu/news/faculty_students/regents_a...
Research Questions Transplant Safety ProcedureResearch Questions Transplant Safety Procedure
2004-04-01
Source: Michigan State University
ScienceDaily
Lyophilization, a method once thought to inactivate retroviruses such as HIV from bones
http://www.sciencedaily.com/releases/2004/04/04040...
Research Questions Transplant Safety ProcedureResearch Questions Transplant Safety Procedure
2004-04-01
source: Michigan State University
Science Daily
Lyophilization, a method once thought to inactivate retroviruses such as HIV from bones an
http://www.sciencedaily.com/releases/2004/04/04040...
Riding the IT Success Wave
Riding the IT Success Wave
April 27, 2007
By Seema Singh
Red Herring
Indian life sciences industry builds momentum in contract services.
The wave started with information technology and has no
http://www.redherring.com/Article.aspx...
Role of Statistics in Lyophilization or Freeze DryingRole of Statistics in Lyophilization or Freeze Drying
Thomas A. Jennings, Ph.D.
January 2003
INSIGHT
There is little doubt, at least in my mind, that lyophilization or freeze drying (see INSIGHT V
http://www.phase-technologies.com/html/vol._6_no._...
Safer, More Stable ProductsSafer, More Stable Products
November 01, 2004
Thomas W. Patapoff and David E. Overcashier
BioPharm International
The freezing method used during lyophilization can substantially affect the structu
http://www.biopharminternational.com/biopharm/arti...
Sanofi?s new Eloxatin consolidates its strong positionSanofi?s new Eloxatin consolidates its strong position
09/02/2005
DrugResearcher.com
FDA?s approval of Sanofi-Aventis? Eloxatin (oxaliplatin) is unlikely to increase the drug?s patient base, but t
http://www.drugresearcher.com/news/ng.asp...
SARS vaccine offers food for thoughtSARS vaccine offers food for thought
June 13, 2005
Canadian Press
Hold the pickles, hold the lettuce, but if you want immune protection against SARS, don't hold the tomato.
American researchers h
http://www.theglobeandmail.com/servlet/story/RTGAM...
Shell Bath offers safe way to pre-freeze multiple flasksShell Bath offers safe way to pre-freeze multiple flasks
Dec 13, 2004
Product News Network
Self-contained VirTis Benchtop Shell Bath produces frozen product coating to inside of freeze-drying fla
http://www.findarticles.com/p/articles/mi_m0PIL/is...
Shell freezer offers efficiency and convenienceShell freezer offers efficiency and convenience
February 8, 2005
LaboratoryTalk
The VirTis benchtop shell bath is a self-contained, compact freezing unit designed for the preparation of flask sampl
http://www.laboratorytalk.com/news/bop/bop107.html
Skin tests with native, depigmented and glutaraldehyde polymerized allergen extracts.Skin tests with native, depigmented and glutaraldehyde polymerized allergen extracts.
2005
Casanovas M, Gomez MJ, Carnes J, Fernandez-Caldas E., Laboratorios LETI, Tres Cantos, Madrid, Spain.
J Inv
Skin tests with native, depigmented and glutaraldehyde polymerized allergen extr...
Small scale freeze dryer is big on featuresSmall scale freeze dryer is big on features
News from: Biopharma Process Systems
Processingtalk Editorial Team on 11 February 2003
This is why the VirTis AdVantage single shelf freeze dryer is so p
http://www.processingtalk.com/news/bop/bop100.html
Solid lipid nanoparticles as drug delivery systems.Solid lipid nanoparticles as drug delivery systems.
March 2005
Manjunath K, Reddy JS, Venkateswarlu V.
Methods Find Exp Clin Pharmacol. 2005 Mar;27(2):127-44.
PubMed
You can view the abstract onl
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...
Some Leading Edge Prospects in LyophilizationSome Leading Edge Prospects in Lyophilization
Summer 2003
Professor Louis Rey, Ph.D., Chemin de Verdonnet 2, CH 1010 Lausanne, Switzerland
APR
Introduction
The development of Lyophilization/Free
http://www.americanpharmaceuticalreview.com/articl...
Stabilization of DNA utilizing divalent cations and alcoholStabilization of DNA utilizing divalent cations and alcohol
October 2003
Jefferson D. Knight 1, and Roger C. Adami
Department of Pharmaceutical Research and Development, Pfizer Global Research and
http://www.sciencedirect.com/science...
Stem Cells, Fat Tissue as Routes to Cell-Based TherapyStem Cells, Fat Tissue as Routes to Cell-Based Therapy
1 June 2005
Neil Canavan
Drug Discovery & Development
Despite cost and regulatory hurdles, inroads from the bench, the desk, and even the gre
http://www.dddmag.com/ShowPR.aspx...
STERIS CorporationSTERIS Corporation
11/1/2003
Pharmaceutical Processing
Product Line: STERIS is a world leader in the manufacture of FDA, cGMP and GAMP-compliant LYOVAC[R] freeze-drying systems, which are built to
http://www.highbeam.com/library/doc0.asp...
Stop The Bleeding, NowStop The Bleeding, Now
[Spring 2004]
by Angela Spivey
Endeavors, UNC-Chapel Hill
Three decades of work with freeze-dried platelets could soon help save lives on the battlefield.
Frank has been a
http://research.unc.edu/endeavors/spr2004/platelet...
Strategies in Development of Lyophilized ParenteralStrategies in Development of Lyophilized Parenterals
Edward Trappler, Lyophilization Technology, Inc.
For lyophilized parenteral preparations, as with any dosage form, product design parameters and
http://www.americanpharmaceuticalreview.com/articl...
Students Take Smarts To State Science FairStudents Take Smarts To State Science Fair
Jason DeRusha reports
Apr 4, 2005
WCCO
St. Paul (WCCO) Hundreds of Minnesota kids will be showing off their science smarts Monday at the Minnesota Acade
http://wcco.com/localnews/local_story_094103517.ht...
Superporous Hydrogels for Pharmaceutical & Other ApplicationsSuperporous Hydrogels for Pharmaceutical & Other Applications
Kinam Park, PhD, Akina, Inc.
Drug Delivery Technology
Please visit the web site to view the article in its entirety.
INTRODUCTION
For
http://www.drugdeliverytech.com/cgi-bin/articles.c...
THE BIG FREEZE DRYTHE BIG FREEZE DRY
February 2004
saf-T-News
Take an organic substance. Now, remove the water (or other solvent). Remove enough to preserve the substance and in such a way that the cell structures a
http://www.labsafety.com/refinfo/saftnews/stn161.h...
The Current State of PAT in Freeze-DryingThe Current State of PAT in Freeze-Drying
January/February 2005
1Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwing-Maximilians-University, Munich
2Boehringer Ingelheim
http://www.americanpharmaceuticalreview.com/articl...
The Evolution of Parenteral Drug PackagingThe Evolution of Parenteral Drug Packaging
March 2004
Jenevieve Blair Polin
PMPN
Newer configurations and materials expand the options for packaging parenteral products.
Prefilled syringes are a
http://www.devicelink.com/pmpn/archive/04/03/001.h...
The Ins and Outs of Prefilled SyringesThe Ins and Outs of Prefilled Syringes
May 2003
by Jenevieve Blair Polin, Contributing Editor
Pharmaceutical & Medical Packaging
Pharmaceutical companies are realizing the benefits of prefilled sy
http://www.devicelink.com/pmpn/archive/03/05/001.h...
The Market Need for Reconstitution Systems
The Market Need for Reconstitution Systems
11/2006
By Graham Reynolds Vice President, Reconstitution and Transfer Systems West Pharmaceutical Services, Inc.
Pharmaceutical Processing
As the numb
http://www.pharmpro.com/ShowPR.aspx...
The process development challenge for a new vaccineThe second critical step in the process was to make a vaccine for rapid evaluation in the clinic (assessed by its ability to generate antibodies against the HPV virus), recognizing that the method use
http://www.nature.com/nm/journal/v11/n4s/full/nm12...
Theoretical prediction of ?optimal? freezing programmesTheoretical prediction of ?optimal? freezing programmes
H. Woelders, and A. Chaveiro
8 December 2004
Elsevier Inc.
Abstract
We have developed a quantitative description of the osmotic behaviour
http://www.sciencedirect.com/science...
Thermostability of VaccinesThermostability of Vaccines
2003
Mrudula K. Lala
Kamlesh R. Lala
Indian Pediatrics
Cold chain is the system of transporting, storing and distributing vaccine in a potent state at recommended tem
http://www.indianpediatrics.net/apr2003/apr-311-31...
Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate Their Intracellular pH.Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate Their Intracellular pH.
2004
Fern Tablin, VMD, PhD1, Minke Tang, PhD1,2,*, Naomi J. Walker, BS1,* and John H. Crowe,
Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate ...
UC Davis finds market for freeze-dried blood plateletsUC Davis finds market for freeze-dried blood platelets
Celia Lamb
February 9, 2004
Sacramento Business Journal
Researchers at the University of California Davis have developed a technology for fre
http://www.bizjournals.com/industries/health_care/...
Ultra Structure of Lyophilized Human Amniotic MembraneUltra Structure of Lyophilized Human Amniotic Membrane
2005
T. Rodriguez?Ares1,A, M.J. L?pez? Valladares1,A, R. Tourino Peralba1,A, B. Vieites1,B, M. Silva1,C and J. Couceiro1,C
Investigative Oph
http://abstracts.iovs.org/cgi/content/abstract/46/...
US: will potatoes help prevent hepatitis E?US: will potatoes help prevent hepatitis E?
June 1, 2005
FreshPlaza
Researchers in the U.S. and Japan are trying to develop an oral vaccine to prevent hepatitis E ? with a little hard work, it may
http://www.freshplaza.com/2005/01jun/2_us_hepatiti...
Usifroid acquires loading system expertiseUsifroid acquires loading system expertise
News from: Biopharma Process Systems
Edited by: Processingtalk Editorial Team on 27 January 2005
Biopharma is pleased to announce that the renowned freeze
http://www.processingtalk.com/news/bop/bop112.html
Vaccine reconstitution and administrationVaccine reconstitution and administration
last updated 10-Jan-2005
WHO
Vaccines are produced in two different forms: as a liquid, which is ready to administer, or as a freeze-dried powder that mus
http://www.who.int/vaccines-access/vacman/reconst/...
Vaccines on the Road to RecoveryImproving manufacturing
But production of the vaccines could be a problem, according to a report published last year by the International AIDS Vaccine Initiative. The report cites two main challenge
http://www.dddmag.com/ShowPR.aspx...
Venus Remedies to set up plant in HPVenus Remedies to set up plant in HP
4/11/2005
India Infoline Ltd
Venus Remedies Ltd on Monday said that it has acquired 5 acres of land for setting up an exclusive manufacturing facility at Baddi,
http://www.indiainfoline.com/news/news.asp...
Vetter keeps on expanding lyophilisation services
Vetter keeps on expanding lyophilisation services
11/08/2006
by Emilie Reymond
In-PharmaTechnologist.com
Germany?s Vetter Pharma-Fertigung has announced its plan to expand its services by adding
http://www.in-pharmatechnologist.com/news/ng.asp.....
Vetter Pharma-Fertigung Launches Major ExpansionVetter Pharma-Fertigung Launches Major Expansion
June 22, 2005
PharmaManufacturing.com
Vetter Pharma-Fertigung GmbH & Co. KG (Ravensburg, Germany), an international contract manufacturer with a foc
http://www.pharmamanufacturing.com/industrynews/20...
When it comes to lyophilization, we take the cakeWhen it comes to lyophilization, we take the cake
10/1/2003
Pharmaceutical Technology
What's the surest path to a bigger ROI? The unparalleled customer service you can get from Baxter Pharmaceutic
http://www.highbeam.com/library/doc0.asp...
Why Lyophilize?Why Lyophilize?
August/September 2003
By Walt Pebley
PharmaQuality
Lyophilization is traditionally used for preserving heat-sensitive parenterals. The elegance of lyophilization or
?low-temper
http://www.pharmaquality.com/Feature2.htm
Why do We Use RTD?s to Monitor the Freeze Drying Process?Why do We Use RTD?s to Monitor the Freeze Drying Process?
June 2003
Thomas A. Jennings, Ph.D.
Insight
The question posed by the title of this INSIGHT is one that I have often asked myself and pose
http://www.phase-technologies.com/html/vol._6_no._...
Will potatoes help prevent hepatitis E?Will potatoes help prevent hepatitis E?
May 31, 2005
By Anna Groner
Checkbiotech
ITHACA / TOKYO / TEMPE - Researchers in the U.S. and Japan are trying to develop an oral vaccine to prevent hepat
http://www.checkbiotech.org/root/index.cfm...
With demand lacking, smallpox vaccine expiringWith demand lacking, smallpox vaccine expiring
August 23, 2003
By Stephen Smith, Globe Staff
UCLA Department of Epidemiology
The Bush administration's campaign to vaccinate health workers against
http://www.ph.ucla.edu/epi/bioter/spoxvacexpiring....
With Plasma, There?s No Immunity From ChallengesWith Plasma, There?s No Immunity From Challenges
July 2005
by Pan Demetrakakes
Food & Drug Packaging
The immunoglobulin therapies packaged at the main Talecris plant are among the most demanding
http://www.fdp.com/content.php...
Young PhD makes progress on pharmaceutical drying techniquesYoung PhD makes progress on pharmaceutical drying techniques
February 18, 2005
University of Saskatchewan
The U of S has its own Doogie Howser. And although he may not be a teenage whiz-kid doctor
http://www.usask.ca/communications/ocn/05-feb-18/p...
Zydus Cadila gears up for Brazil in AprilZydus Cadila gears up for Brazil in April
FEBRUARY 24, 2005
TIMES NEWS NETWORK
AHMEDABAD: Zydus Cadila is all set to enter the lucrative generics market in Brazil in April. The Rs 1,170 crore pharm
http://economictimes.indiatimes.com/articleshow/ms...