A novel RNA synthetic method with a 2'-O-(2-cyanoethoxymethyl) protecting group 2006 Yoshinobu Shiba, Hidetoshi Kitagawa, Yutaka Masutomi, Kouichi Ishiyama, Tadaaki Ohgi and Junichi Yano Discove

Activation Of MicroRNA Inhibits Cancer Gene In Human Cancer Cells 6/13/2006 Bioresearch Online Scientists report that tumor cells display a dramatic reduction of cancer-causing genes when a n

Amino acid residue doublet propensity in the protein?RNA interface and its application to RNA interface prediction November 27, 2006 Oanh T. P. Kim1, Kei Yura1,2,3,* and Nobuhiro Go2 1 Quantum B

An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis mediated by RNase L 2006 Tomoharu Naito1, Tatsushi Yokogawa1, Hye-Sook Kim1, Akira Matsuda2, Takuma Sasak

Bacterial delivery of functional messenger RNA to mammalian cells May 2005 Christoph Schoen, Annette Kolb-M?urer, Gernot Geginat, et. Cell Microbiol The limited access to the nuclear compartme

Brain :: RNA map provides first comprehensive understanding of alternative splicing November 9, 2006 SpiritIndia.com new RNA map, created by a team of researchers at Rockefeller University and t

Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: quantitative analysis of uptake and biological effect November 28, 2006 Sandra Veldhoen, Sandra D.

Chemical synthesis of RNA including 5-taurinomethyluridine 2006 Toshihiko Ogata and Takeshi Wada Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The Universitiy of T

Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules Feb 2006 Jiehua Zhou, Jiangyu Wu, Xiaoxuan Liu, et. al. Org Biomol Chem Tri(ethylene

CRE recombinase-inducible RNA interference mediated by lentiviral vectors 2004-05-11 Recently, several systems designed to trigger RNA interference by using small hairpin RNA driven by polymerase

Development of methods for RNA interference in the sheep gastrointestinal parasite, Trichostrongylus colubriformis Aug 2005 Z Issa, W N Grant, S Stasiuk Int J Parasitol The efficiency of RNA

Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 RNA in breast milk and on postnatal transmission Oct 2004 Olivier Manigart, Montcho Crepin, Valeriane Leroy, et. al.

Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions Sep 2005 Chava Kimchi-Sarfaty, Scott Brittain, Susan Garfield, et. al. Hum Gene Ther Previously we hav

EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice JANUARY 2006 Alexei Shir1, Manfred Ogris2, Ernst Wagner2, Alexander L

Flexizyme as a versatile tRNA acylation catalyst and the application for translation 2006 Hiroshi Murakami1, Atushi Ohta2, Yuki Goto1, Yusuke Sako2 and Hiroaki Suga1,2 1 Research Center for Adva

Gene silencing in the development of personalized cancer treatment: the targets, the agents and the delivery systems 2006 Aug Verreault M, Webb MS, Ramsay EC, Bally MB. Curr Gene Ther. The adven

Hairpins for Switches: Artificial RNA ligands differentiate between on and off states of riboswitches December 8, 2006 Physorg.com How does an organism know when it must produce a protein and in

High-throughput method for the prediction of low-resolution, three-dimensional RNA structures 2006 Mariusz Popenda, ukasz Bielecki and Ryszard W. Adamiak Laboratory of Structural Chemistry of Nu

HIV gene therapy using RNA virus systems 2006 Masaaki Hayafune1, Naoko Miyano-Kurosaki1,2, Akiko Kusunoki1, Yuka Mouri1 and Hiroshi Takaku1,2 1 Department of Life and Environmental Science, Chib

Identification of antisense RNA stem-loops that inhibit RNA-protein interactions using a bacterial reporter system 2006 Akiko Yano, Mayumi Kunimoto, Takako Minami and Kazuo Harada Department of

Increasing Resistance of Tubular Epithelial Cells to Apoptosis by shRNA Therapy Ameliorates Renal Ischemia-Reperfusion Injury 2006 Oct Du C, Wang S, Diao H, Guan Q, Zhong R, Jevnikar AM. Am J Tra

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice 2005 Rodriguez-Lebron E; Denovan-Wright

Kinetic analysis of ribosome binding process onto mRNA using a quartz-crystal microbalance 2006 Shuntaro Takahashi1, Ryoko Akita1, Hiroyuki Furusawa1, Yoshihiro Shimizu2, Takuya Ueda2 and Yoshio O

Lessons from Nature: microRNA-based shRNA libraries 2006 Sep Chang K, Elledge SJ, Hannon GJ. Nat Methods. Loss-of-function genetics has proven essential for interrogating the functions of gene

More Effective RNA-Based Drugs 2006 By Katherine Bourzac MIT Technology Review The ability to shut downspecific disease-causing genes could be a powerful weapon against cancer and infections suc

Nanoparticles Improve Antisense Delivery and Expression May 22, 2006 NCI In the fight against cancer, antisense drugs that could block cancer genes from producing malicious proteins have the pote

New delivery technology paves way for disease therapies May 26, 2005 Harvard College A new way to administer therapeutic RNA molecules that efficiently guides them to cells throughout the body

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice July 2, 2004 Donald Massaro, Gloria DeCarlo Massaro, and Linda Biadasz Clerch Am J Physiol Lung Cell M

NuGEN launches Ovation whole blood solution and RNA amplification system 7 December 2006 Medical Technology Business Europe SAN CARLOS, Calif.--(BUSINESS WIRE)--NuGEN, Technologies, Inc., has ann

Peering into the shadow world of RNA December 4, 2006 SpiritIndia.com The popular view is that DNA and genes control everything of importance in biology. The genome rules all of life, it is thoug

Purdue Scientists Treat Cancer With RNA Nanotechnology 9/15/2005 Bioresearch Online West Lafayette, IN ? Using strands of genetic material, Purdue University scientists have constructed tiny del

RNA delivery by heat shock protein-70 into mammalian cells: A preliminary study May 2006 Tam?s Henics Cell Biol Int Heat shock proteins (Hsps) are ubiquitous molecular chaperones with indispen

RNA interference in immune cells by use of osmotic delivery of siRNA Mar 2006 Mikio Aoki, Takayuki Ishii, Masaharu Biochem Biophys Res Commun Delivery of siRNA to immune cells has been one of

RNA recognition and recognition control of -peptide ribonucleic acids containing arginine residue by external factors 2006 Takehiko Wada1,2, Yoshiki Maeda1, Nobuya Sawa1, Hirofumi Sato2, Shiroh Fu

RNA Silencing Sheds Light on the RNA World December 5, 2006 Dr. Priya Saxena RxPG News RNA silencing ? also known as RNA interference ? is an intriguing phenomenon in which short, double-strande

RNAi tackles a sexually transmitted disease 2006 Patricia Cristofaro & Bharat Ramratnam Nature Biotechnology Herpes simplex virus-2 (HSV-2) infection has reached epidemic proportions, with serop

Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells December 1, 2006 Ross J. Molinaro

Sequence-dependent formation of intrastrand crosslink products from the UVB irradiation of duplex DNA containing a 5-bromo-2'-deoxyuridine or 5-bromo-2'-deoxycytidine November 27, 2006 Yu Zeng an

Sequence-dependent gating of an ion channel by DNA hairpin molecules November 27, 2006 Veronica S. DeGuzman1,2, Clarence C. Lee3, David W. Deamer4 and Wenonah A. Vercoutere5,* 1 Ames Associate,

Silencing RNA: a novel treatment for pancreatic cancer? 2005 N R Lemoine BMJ Publishing Group Ltd & British Society of Gastroenterology The antiapoptotic gene Bcl-2 has been a target for downre

Small RNA?s Move into the Spotlight 11 Oct 2005 By Jessica Shah Historically, biological research worldwide has focused primarily on genes, the functional sections of deoxyribonucleic acid (DNA)

Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA Sep 2005 Songchuan Guo, Nuska Tschammer, Sulma Mohammed Hum Gene Ther The application

Tandem Transcripts Team Together 1/6/2006 Bioresearch Online In the January issue of the journal Genome Research, two teams of scientists describe a widespread phenomenon in the human genome

The interaction networks of structured RNAs October 25, 2006 A. Lescoute and E. Westhof Nucleic Acids Research All pairwise interactions occurring between bases which could be detected in three-

The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing November 28, 2006 Kathryn S. Sciabica and Klemens J. Hertel* Department of Microbiology and Molecular Ge

The Structure of a Rigorously Conserved RNA Element within the SARS Virus Genome January 2005 Michael P. Robertson1,2, Haller Igel1,3, Robert Baertsch1,4, David Haussler1,4, Manuel Ares1,3, Willia

Therapeutic potential of RNA interference for neurological disorders Received 21 March 2006; accepted 2 June 2006. Available online 15 June 2006. Dinah W.Y. Saha Life Sciences Volume 79, Iss

TOPIGEN Begins IND-Enabling Studies for TPI-1100 the First RNA-Targeting Compound to Treat COPD 9/18/2006 GEN TOPIGEN Pharmaceuticals Inc., an emerging biopharmaceutical company specializing in

Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides 2006 Aug 4 Xu Q, Katkevica D, Rozners E. J Org Chem. Chemical reaction: see text] Recent discovery

Treating Cancer with RNA Nanotechnology 9/15/05 Elizabeth Tolchin Advantage Business Media Using RNA nanotechnology researchers say they constructed delivery vehicles that can carry anticancer

Twin Molecular Scissors Link Creation Of MicroRNAs With Gene-Silencing 11/4/2005 Bioresearch Online New insights into vital genome regulation strategy provided Philadelphia ? One of the body

University emerges as important center for small RNA research Dec. 6, 2006 University of Delaware The University of Delaware is emerging as an important center for research on small ribonucleic a

University Of Pennsylvania Researchers Find Role For MicroRNAs In Oxygenation, Nourishing Of Colon Tumors 8/1/2006 Bioresearch Online Philadelphia - Researchers from the University of Pennsylvani

Vaccination with messenger RNA 2006 Pascolo S. Methods Mol Med. As an alternative to DNA-based vaccines, messenger RNA (mRNA)-based vaccines present additional safety features: no persistence, n

Vector-based in vivo RNA interference: dose- and time-dependent suppression of transgene expression Feb 2004 Naoki Kobayashi, Yumi Matsui, Atsushi Kawase, et. J Pharmacol Exp Ther RNA interfere