A composite gene delivery system consisting of polyethylenimine and an amphipathic peptide KALA 2006 Sep 29 Min SH, Lee DC, Lim MJ, Park HS, Kim DM, Cho CW, Yoon DY, Yeom YI. J Gene Med. BACKG

A novel method for the preparation of biodegradable microspheres for protein drug delivery 2006 Aug 22 Pareta R, Edirisinghe MJ. J R Soc Interface. Microspheres are potential candidates for

A TAT?streptavidin fusion protein directs uptake of biotinylated cargo into mammalian cells April 8, 2005 Brian Albarran, Richard To and Patrick S. Stayton Oxford Journals The HIV-1 TAT peptide

Activated Protein C Inhibits Local Coagulation after Intrapulmonary Delivery of Endotoxin in Humans March 4, 2005 Tom van der Poll, Marcel Levi, Jerry A. Nick and Edward Abraham American Thoraci

Alginate?whey protein granular microspheres as oral delivery vehicles for bioactive compounds September 2006 Lingyun Chena and Muriel Subirade Biomaterials Abstract Alginate (AL)?whey protein

Amine-Functionalized Sba-15 on Protein Delivery: Adsorption, Release and Stability of Bovine Serum Albumin 16 November 2006 Shiwei Song1, Kus Hidajat1, and Sibudjing Kawi2. (1) Department of Chemi

Amphiphilic Self-assembled Nanoparticles Composed of Chitosan and Ursolic Acid for Protein Delivery on the Skin 2006 S.B. Lee, K. Cho and J.K. Shim Korea Institute of Industrial Technology, KR

An intracellular delivery vehicle for protein transduction of micro-dystrophin 2005 Feb Richard H Weisbart, James E Hansen, Robert N Nishimura, Grace Chan, Rika Wakelin, Sophia S Chang, Larry Bare

Applying Process Analytical Technology to Biotech Unit Operations Aug 1, 2006 By: Anurag S. Rathore, Ashutosh Sharma, David Chilin BioPharm International ABSTRACT Case studies were run t

Arginine-rich intracellular delivery peptides noncovalently transport protein into living cells 4 August 2006 Ya-Hui Wanga, Chung-Pin Chena, Ming-Huan Chanb, Microsugar Changa, Yu-Wun Houa, Hwei-

Avecia paves way for more efficient protein production 08/05/2007 by Pete Mansell DrugResearcher.com This news is provided by: In-PharmaTechnologist.com The Biologics division of UK company

Biodegradable Microspheres as Carriers for Native Superoxide Dismutase and Catalase Delivery November 5, 2004 Stefano Giovagnoli,1 Paolo Blasi,1 Maurizio Ricci,1 and Carlo Rossi1 1Department

Biomimetic approaches to protein and gene delivery for tissue regeneration Available online 22 May 2006. Stelios T. Andreadis and David J. Geer Trends in Biotechnology Novel therapeutic strat

Bulking Up on Protein Drugs JR Minkel, a freelance writer based in Brooklyn, N.Y. DrugDiscovery & Development Magazine The "cryo-coma" in the clinical protein manufacturing facility of Wyeth BioPha

CellCircuits: a database of protein network models November 29, 2006 H. Craig Mak, Mike Daly, Bianca Gruebel and Trey Ideker Nucleic Acids Research CellCircuits (http://www.cellcircuits.org) is

Chronic gene delivery of interferon-inducible protein 10 through replication-competent retrovirus vectors suppresses tumor growth 2005 Nov Sun Y, Finger C, Alvarez-Vallina L, Cichutek K, Buchholz

Combined approach to the analysis of recombinant protein drugs using hollow-fiber flow field-flow fractionation, mass spectrometry, and chemiluminescence detection 2006 Roda A; Parisi D; Guardigli

Comparison of monomeric and oligomeric transferrin as potential carrier in oral delivery of protein drugs Sep 2005 Ching-Jou Lim J Control Release Oligomeric transferrin (Tf) was used to investi

Compound Reveals New Link Between Signaling Protein And Cell Migration 9/26/2005 Bioresearch Online University of Illinois at Chicago researchers report that a protein that regulates key sign

Conformation-specific affinity purification of proteins using engineered binding proteins: Application to the estrogen receptor June 2006 Jin Huanga, Akiko Koidea, Kendall W. Nettleb, Geoffrey L.

Core/Shell nanoparticles with lecithin lipid cores for protein delivery 2006 Aug Oh KS, Han SK, Lee HS, Koo HM, Kim RS, Lee KE, Han SS, Cho SH, Yuk SH. Biomacromolecules. Core/shell nanoparticl

Delivery of antibody-captured proteins into living cells using PTD-fused protein A June 28, 2006 Masayasu Mie, Kazuto Mori, Hisakage Funabashi and Eiry Kobatake Springer Abstract Protein trans

Development of phosphorylated glucomannan-coated chitosan nanoparticles as nanocarriers for protein delivery 2006 Sep-Oct Cuna M, Alonso-Sandel M, Remunan-Lopez C, Pivel JP, Alonso-Lebrero JL, Alo

Different ratios of lactide and glycolide in PLGA affect the surface property and protein delivery characteristics of the PLGA microspheres with hydrophobic additives 2006 Feb Chung TW, Tsai YL, H

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery 2006 May Ratajczak J, Miekus K, Kucia M, Zhang J, Reca

Evaluation of critical formulation parameters influencing the bioactivity of ?-lactamases entrapped in pectin beads Received 16 February 2006; revised 23 May 2006; accepted 25 May 2006. Availabl

Exogenous expression of proteins in neurons using the biolistic particle delivery system 2006 Gamper N, Shapiro MS. Methods Mol Biol. Exogenous expression of genes in mammalian neurons represe

Fucosphere--new microsphere carriers for peptide and protein delivery: preparation and in vitro characterization 2006 Aug Sezer AD, Akbuga J. J Microencapsul. PURPOSE: Fucoidan is a complex pol

Glucose transporter proteins GLUT1 and GLUT3 like immunoreactivities in the fetal sheep brain are not reduced by maternal betamethasone treatment 7 August 2006 Iwa Antonow-Schlorkea, Martin Eberta

In vitro study of lysozyme in poly(lactide-co-glycolide) microspheres with sucrose acetate isobutyrate Received 10 April 2006; revised 8 August 2006; accepted 14 August 2006. Available online 18

Incorporation of a model protein into chitosan-bile salt microparticles 2006 Apr 7 Lameiro MH, Lopes A, Martins LO, Alves PM, Melo E. Int J Pharm. In order to develop a mucosal delivery system

Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclas

Inductive tissue engineering with protein and DNA-releasing scaffolds 25th November 2005 David M. Salvaya and Lonnie D. Shea Mol. BioSyst. Cellular differentiation, organization, proliferation

Interspecies scaling of protein drugs: prediction of clearance from animals to humans 2004 Mahmood I Division of Clinical Trial Design and Analysis, Office of Therapeutic Research and Review, Foo

Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro 2006 Aug 21 Toro A, Paiva M, Ackerley C, Grunebaum E. Cell I

Intracerebroventricular delivery of dominant negative prion protein in a mouse model of iatrogenic Creutzfeldt-Jakob disease after dura graft transplantation 24 July 2006 Kazuhide Furuyaa, , , Nob

Is the oral route possible for peptide and protein drug delivery? 2006 Oct Morishita M, Peppas NA. Drug Discov Today. Oral delivery of peptides and proteins remains an attractive alternative to

Microencapsulation peptide and protein drugs delivery system 2005 Dai C; Wang B; Zhao H Key Laboratory of Biomechanics & Tissue Engineering under the State Ministry of Education, College of Bioen

MMDB: annotating protein sequences with Entrez's 3D-structure database November 29, 2006 Yanli Wang, Kenneth J. Addess, Jie Chen, Lewis Y. Geer, Jane He, Siqian He, Shennan Lu, Thomas Madej, Aron

Multiple alignment of protein sequences with repeats and rearrangements 2006 Oct 26 Phuong TM, Do CB, Edgar RC, Batzoglou S. Department of Computer Science, Posts & Telecommunications Institute

Nano-submarines for drug delivery 21-05-2007 Thijs Westerbeek Radio Netherlands War-submarines that travel through our bodies looking for alien invaders; molecular battle ships that know exactl

Nanoparticulate Drug Delivery Systems Based on Hydrotropic Polymers, Dendrimers, and Polymer Complexes 2005 J.H. Park, K.M. Huh, S.C. Lee, W-K Lee, T. Ooya and K. Park Nanotech 2005 Novel nanopa

Nanotech could improve protein delivery 24/03/2004 Decision News Media SAS Access Pharmaceuticals has signed an agreement with an unnamed US partner for a drug delivery system based on nanoparti

Nanotechnologies in protein delivery 2006 Sep-Oct Salmaso S, Bersani S, Semenzato A, Caliceti P. J Nanosci Nanotechnol. The growth rate for biotech drugs, namely proteins, peptides, and oligonu

New Family Of Biodegradable Polymers Shows Promise For Intracellular Drug Delivery 30 Mar 2006 Medical News Today A newly developed family of biodegradable polymers has shown potential for use i

New Understanding Of Ewing's Sarcoma Suggests Novel Treatment Strategy 6/2/2006 Bioresearch Online Washington, D.C. - Using molecular and cell-based models, researchers at Georgetown University M

Normal flora: living vehicles for non-invasive protein drug delivery 2004 Nov 22 Shao J, Kaushal G. Int J Pharm. Feasibility to use probiotic bacteria as a living protein delivery system throu

Novel Methods Of Modification And Production Of Peptides & Proteins For Therapeutic Use 8/29/2006 Activotech Bioresearch Online Activotec has an extensive ongoing R&D program targeted at develo

Optimizing the binding affinity of a carrier protein: a case study on the interaction between soluble ifnar2 and interferon beta Apr 2004 Tal Peleg-Shulman, Laila C Roisman, Gordin Zupkovitz J Bi

Oral gene therapy: a novel method for the manufacture and delivery of protein drugs 2005 Rothman S; Tseng H; Goldfine I University of California, San Francisco, San Francisco, California 94708, U

ORNL, Protein Discovery Researchers Collaborate On High-Profile Paper 4/13/2006 Bioresearch Online Oak Ridge, TN - A paper that outlines a new method to use a beam of light to trap protein mole

Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: Comparison of adenovirus mediated gene transfer and protein delivery of BMP-2 October 2006 Lorenz Meinela, b, c, 1, Sand

Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs 2005 Ke WT; Lin SY; Ho HO; She

PKA delivery to the distal lung air spaces increases alveolar liquid clearance after isoproterenol-induced alveolar epithelial PKA desensitization 19 April 2005 Michael B. Maron,1 Hans G. Folkess

Polyarginine-mediated protein delivery to dendritic cells presents antigen more efficiently onto MHC class I and class II and elicits superior antitumor immunity 2006 Aug Mitsui H, Inozume T, Kita

Postfabrication encapsulation of model protein drugs in a negatively thermosensitive hydrogel Aug 2005 Ying Zhang, Wen Zhu, Biaobing Wang, et. al. J Pharm Sci A postfabrication encapsulation t

Potential Biologic Therapies for the Intervertebral Disc 2006 Christopher Evans, PhD, DSc JB&JS The author did not receive grants or outside funding in support of his research for or preparatio

Production Of Key Alzheimer's Protein Monitored For First Time In Humans 6/26/2006 Bioresearch Online Test could improve diagnosis and treatment, help scientists better understand causes of dem

Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery 11 May 2006 Sunday A. Shoyele, and Alex Slowey International Journal of Pharmaceutics Abstract Formulation

Protein delivery into eukaryotic cells by type III secretion machines 30 November 2006 Jorge E. Gal?n1 and Hans Wolf-Watz Nature Bacteria that have sustained long-standing close associations wit

Protein Delivery Systems 2006 N. A. Peppas and C. Donini Encyclopedia of Biomaterials and Biomedical Engineering More effective and tailored drug delivery systems (DDS) are continuously investi

Protein Peeling 2: a web server to convert protein structures into series of protein units April 6, 2006 J.-C. Gelly, C. Etchebest, S. Hazout, and A.G. de Brevern Nucleic Acids Research Protein

Protein protection for genetic delivery May 2004 Jon Evans Royal Society of Chemistry Microcapsules offer a novel route for DNA-based drugs. Medicines based on DNA, whether gene therapy or DNA

Protein stability in the presence of polymer degradation products: Consequences for controlled release formulations June 2006 Amy S. Determana, Jennifer H. Wilsonb, Matt J. Kippera, Michael J. Wan

Putting Proteins on the Map 2006 by Robert F. Murphy Nature Biotechnology A combination of microscope technology and statistical analysis enables the identification of proteins that share subcel

Researchers Find Protein That Silences Genes 5/5/2006 Bioresearch Online How genes get deep-sixed A team of researchers, including biologists at Washington University in St. Louis, has disco

Retrieval accuracy, statistical significance and compositional similarity in protein sequence database searches October 26, 2006 Yi-Kuo Yu, E. Michael Gertz, Richa Agarwala, Alejandro A. Sch?ffer

RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules February 16, 2006 WEI-HONG YANG, JIANG HONG YU, TOD GULICK, KENNETH D. BLOCH3 and DONALD B. BLOCH RNA Th

SAFC completes protein purification capacity expansion 03/05/2007 By Emilie Reymond In-PharmaTechnologist.com This news is provided by: DrugResearcher.com SAFC Pharma, the contract manufactur

Saporin as a novel suicide gene in anticancer gene therapy 2006 Sep 29 Zarovni N, Vago R, Solda T, Monaco L, Fabbrini MS. Cancer Gene Ther. We used a non-viral gene delivery approach to explore

Sentra: a database of signal transduction proteins for comparative genome analysis November 29, 2006 Mark D'Souza,*, Elizabeth M. Glass, Mustafa H. Syed, Yi Zhang, Alexis Rodriguez, Natalia Malts

SISYPHUS--structural alignments for proteins with non-trivial relationships 2006 Oct 26 Andreeva A, Prlic A, Hubbard TJ, Murzin AG. MRC Centre for Protein Engineering Hills Road, Cambridge CB2 2

Solid-phase translation and RNA?protein fusion: a novel approach for folding quality control and direct immobilization of proteins using anchored mRNA October 24, 2006 Manish Biyani,*, Yuzuru Hus

Stem cell-derived erythroid cells mediate long-term systemic protein delivery 2006 Aug Chang AH, Stephan MT, Sadelain M. Nat Biotechnol. We demonstrate here the capacity of erythroid cells to

Stimuli-sensitive protein delivery systems 2006 N.A. Peppas*, B. Kim J. DRUG DEL. SCI. TECH. The development of stimuli-sensitive release systems for protein and peptide delivery has been a subj

Strategies to improve plasma half life time of peptide and protein drugs 2006 Werle M; Bernkop-Schn?rch A ThioMatrix GmbH, Research Center Innsbruck, Innsbruck, Austria Amino Acids Due to the o

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device Available online 24 August 2005. Henry Hebela, , Heather A

Synthesis and characterization of biocompatible poly(organophosphazenes) aiming for local delivery of protein drugs 2006 Seong JY; Jun YJ; Kim BM; Park YM; Sohn YS Department of Chemistry, Divisi

Systemic protein delivery by muscle-gene transfer is limited by a local immune response 1 June 2005 Lixin Wang, Eric Dobrzynski, Alexander Schlachterman, Ou Cao, and Roland W. Herzog Blood First

TAT-mediated endocytotic delivery of the loop deletion Bcl-2 protein protects neurons against cell death 2005 Oct Soane L, Fiskum G. J Neurochem. Protein delivery mediated by protein transduct

Tetanus toxin fragment C fusion facilitates protein delivery to CNS neurons from cerebrospinal fluid in mice 2005 Nov Benn SC, Ay I, Bastia E, Chian RJ, Celia SA, Pepinsky RB, Fishman PS, Brown RH

The biological significance of lipid-protein interactions Engineering Village 2 2006 Elsevier Inc. Accession number: 8992911 Title: The biological significance of lipid-protein interactio

The budding yeast protein Chl1p is required to preserve genome integrity upon DNA damage in S-phase October 24, 2006 Suparna Laha, Shankar Prasad Das, Sujata Hajra, Soumitra Sau and Pratima Sinha

The RA Domain of Ste50 Adaptor Protein Is Required for Delivery of Ste11 to the Plasma Membrane in the Filamentous Growth Signaling Pathway of the Yeast February 2006 Dagmar M. Truckses, Joshua E.

Trans-Golgi network delivery of synaptic proteins in synaptogenesis 2004 Vladimir Sytnyk*, Iryna Leshchyns'ka*, Alexander Dityatev and Melitta Schachner The Company of Biologists Synapse forma

Tripep Produces Additional Positive Data for Its Hepatitis C DNA Vaccine Using Inovio's DNA Delivery System August 28, 2006 Therapeutics Daily SAN DIEGO--(BUSINESS WIRE)--Aug. 28, 2006 - Inovio B

Understanding lyophilization formulation development: the author covers the fundamentals of lyophilization and provides case studies about the development of lyophilized biopharmaceutical products and

What Is A Protein? 8/1/2006 Bioresearch Online A protein (from the Greek protas meaning "of primary importance") is a complex, high-molecular-mass, organic compound that consists of amino acids j