(12) Patent Application: (11) CA 2252374 ABSTRACT: A process for the viral inactivation of lyophilized blood proteins, particularly Factor VIII, by heat comprising forming a stable complex bet

12) Patent Application: (11) CA 2392810 ABSTRACT: The present invention relates to a novel freeze - dried pharmaceutical composition useful for the treatment of migraine and associated symptom

(12) Patent Application: (11) CA 2079895 ABSTRACT: 2079895 9113301 PCTABS00007 This invention introduces an absorption vapor pressure enhancement operation. In the process, a mass of solvent

United States Patent Application 20050136010 Kind Code A1 Haeberlin, Barbara June 23, 2005 Aerosol composition comprising formoterol Abstract The use of dry powder comprising (A) formate

United States Patent Application 20050124586 Kind Code A1 Phan, Hieu Trung ; et al. June 9, 2005 Alpha-substituted arylalkyl phosphonate derivatives Abstract The present invention rela

United States Patent Application 20050124581 Kind Code A1 Phan, Hieu Trung ; et al. June 9, 2005 Alpha-substituted heteroarylalkyl phosphonate derivatives Abstract The present inventio

United States Patent Application 20050085494 Kind Code A1 Daines, Robert A ; et al. April 21, 2005 Aminopiperidine compounds, process for their preparation, and pharmaceutical composition

United States Patent Application 20050153404 Kind Code A1 Bosch, Boris ; et al. July 14, 2005 Anti-kazlauskas lipases Abstract The present invention relates to polypeptides which exert

United States Patent Application 20050148613 Kind Code A1 Van Emelen, Kristof ; et al. July 7, 2005 Carbonylamino-derivatives as novel inhibitors of histone deacetylase Abstract This i

CD4-IgG2 formulations Engineering Village Publication number: US20050142139 Application number: 804802 Unstandardized application number: 10804802 Patent authority: US

United States Patent Application 20050143368 Kind Code A1 Starke, Ingemar ; et al. June 30, 2005 Chemical compounds Abstract The present invention relates to compounds of formula (1):

United States Patent Application 20050152985 Kind Code A1 Janusz, Marin ; et al. July 14, 2005 Colostrinin, and uses thereof Abstract The use of Colostrinin as a medicament, particular

United States Patent Application 20050112188 Kind Code A1 Eliaz, Rom Ezer ; et al. May 26, 2005 Composition and dosage form comprising an amphiphilic molecule as a suspension vehicle Abs

United States Patent Application 20050106240 Kind Code A1 Tanaka, Nobukazu ; et al. May 19, 2005 Composition for rapid disintegrating tablet in oral cavity Abstract The present inventi

United States Patent Application 20050152962 Kind Code A1 Metselaar, Josbert Maarten July 14, 2005 Composition for treatment of inflammatory disorders Abstract A pharmaceutical compositi

United States Patent Application 20050106246 Kind Code A1 Byrd, Edward A. May 19, 2005 Controlled release arginine alpha-ketoglutarate Abstract An oral formulation of arginine .alpha.-ke

United States Patent Application 20020114737 Kind Code A1 Madril, Dominic G. ; et al. August 22, 2002 Abstract The present invention provides a cover plate that covers one or more delive

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United States Patent Application 20050131209 Kind Code A1 Davis, Roderick Gerald ; et al. June 16, 2005 Crystallized hnf4 gamma ligand binding domain polypeptide and screening methods emp

United States Patent Application 20050112201 Kind Code A1 Baichwal, Anand R. ; et al. May 26, 2005 Delayed release dosage forms Abstract A delayed release pharmaceutical formulation co

United States Patent Application 20050084534 Kind Code A1 Ni, Yawei ; et al. April 21, 2005 Delivery of physiological agents with in-situ gels comprising anionic polysaccharides Abstrac

United States Patent Application 20050137167 Kind Code A1 Casu, Benito ; et al. June 23, 2005 Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed wit

United States Patent Application 20020065483 Kind Code A1 Leon, Nathaniel ; et al. May 30, 2002 Disposable unit-dose jet-injection syringe for pre-filled and/or transfilled liquid injecta

United States Patent Application 20050152977 Kind Code A1 Petereit, Hans-Ulrich ; et al. July 14, 2005 Abstract The invention relates to a process for producing a coated drug form or a d

Dry powder inhaler system European Patent Office Publication number: US2006254583 Publication date: 2006-11-16 Inventor: DEBOECK ARTHUR (US); BAUDUER PHILIPPE (BE) Applicant: Classificati

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(12) Patent Application: (11) CA 2012853 Abstract: FREEZE-DRIED POLYMER DISPERSIONS AND THE USE THEREOF IN PREPARING SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITIONS Freeze-dried polymer latices, w

United States Patent Application 20050143419 Kind Code A1 Peyman, Anuschirwan ; et al. June 30, 2005 -------------------------------------------------------------------------------- Guan

United States Patent Application 20030077208 Kind Code A1 Ikenoue, Masaki ; et al. April 24, 2003 Holder for freeze-drying of drug solutions Abstract A holder comprises a base 1 having

United States Patent Application 20020176867 Kind Code A1 Andersen, Peter ; et al. November 28, 2002 Hybrids of M. tuberculosis antigens Abstract The present invention discloses fusion

IL-1 antagonist formulations Engineering Village Publication number: US20060040852 Application number: 11205935 Unstandardized application number: 205935 Patent authority: US

United States Patent Application 20050112193 Kind Code A1 Phillips, Jeffrey O. ; et al. May 26, 2005 Immediate-release formulations of acid-labile pharmaceutical compositions Abstract

In vacuo glycation of proteins Engineering Village Publication number: US20060122369 Application number: 10524547 Unstandardized application number: 524547 Patent authority:

United States Patent Application 20050153902 Kind Code A1 Staehle, Wolfgang ; et al. July 14, 2005 Inhibitors of integrin avb6 Abstract Novel biphenyl derivatives of the general formul

United States Patent Application 20050123593 Kind Code A1 Thompson, Jonathan ; et al. June 9, 2005 Liposomal encapsulation of glycosaminoglycans for the treatment of arthritic joints Ab

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United States Patent Application 20050100590 Kind Code A1 Duena, Antonio Parent ; et al. May 12, 2005 Liposomes encapsulating anticancer drugs and use thereof in the treatment of malignan

United States Patent Application 20040235956 Kind Code A1 Quay, Steven C. November 25, 2004 Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric

United States Patent Application 20020042388 Kind Code A1 Cooper, Mark J. ; et al. April 11, 2002 Abstract Counterions of polycations used to compact nucleic acids profoundly affect shape

United States Patent Application 20010001348 Kind Code A1 Wisniewski, Richard May 24, 2001 Abstract Disclosed are bulk lyophilization containers including aseptic closure portions or heat

ABSTRACT: A lyophilization closure assembly for a container or vial is disclosed. The lyophilization closure assembly is self-supporting with the container and may be employed with the container d

Lyophilization method and apparatus for producing particles US Patent & TradeMark Office United States Patent Application 20040154317 Kind Code A1 Shekunov, Boris Y. ; et al. August 12, 2

(12) Patent Application: (11) CA 2280130 ABSTRACT: An object of the invention is to improve the solubility of a glycosphingolipid having a low solubility in water by preparing a freeze-dried c

(12) Patent Application: (11) CA 2119096 ABSTRACT OF THE DISCLOSURE: There is disclosed a lyophilized control or reference plasma or control or reference serum for diagnostic purposes containing

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(12) Patent Application: (11) CA 2375779 ABSTRACT: Freeze dried preparations containing hepatocyte growth factor (HGF), a stabilizer such as arginine or lysine, sodium chloride and a buffer. T

United States Patent Application 20030099674 Kind Code A1 Chen, Andrew X. May 29, 2003 Lyophilized injectable formulations containing paclitaxel or other taxoid drugs Abstract A stable a

Lyophilized liposome formulations and method Engineering Village Publication number: US20060110441 Application number: 11261983 Unstandardized application number: 261983 Paten

(12) Patent Application: (11) CA 2485827 ABSTRACT: Lyophilized preparations from cell extract for use in cell-free protein, which exhibit an activity for protein synthesis being in no way infe

ABSTRACT: Somatotropin solutions which remain clear for extended periods and which remain clear when subjected to mechanical agitation are prepared by mixing a lyophilized somatotropin composi

United States Patent Application 20030147897 Kind Code A1 Andersen, Peter ; et al. August 7, 2003 M. tuberculosis antigens Abstract The present invention is based on the identification

ABSTRACT: This invention relates to the improvement of arrays of porous polymer pads on solid supports used in biological assays. The invention involves freeze drying the porous polymer pads to in

United States Patent Application 20050131214 Kind Code A1 Gilbert, Teresa ; et al. June 16, 2005 Mammalian cytokine-like factor 7 Abstract Novel mammalian zcyto7 polypeptides, polynucl

United States Patent Application 20020085999 Kind Code A1 Lee, Lucy F. ; et al. July 4, 2002 Marek's disease virus genes and their use in vaccines for protection against marek's disease

United States Patent Application 20050109046 Kind Code A1 Irvine, J. David ; et al. May 26, 2005 Method and apparatus for the manipulation and management of a cryogen for production of fr

United States Patent Application 20050153329 Kind Code A1 Hakansson, Leif ; et al. July 14, 2005 Method for determining immune system affecting compounds Abstract The present invention

United States Patent Application 20040191754 Kind Code A1 Meir, Uri ; et al. September 30, 2004 Abstract A method and a device for improved freezing of biological containing living cells

United States Patent Application 20050002998 Kind Code A1 Chang, Esther H. ; et al. January 6, 2005 Abstract A method for preparing a stable cell-targeting complex comprising a ligand an

United States Patent Application 20040009609 Kind Code A1 Yarborough, Cody L. ; et al. January 15, 2004 Abstract A process for lyophilizing a solution of an active agent in a container i

United States Patent Application 20050148507 Kind Code A1 Wandl, Robert ; et al. July 7, 2005 Method for the production of an N-terminally modified chemotactic factor Abstract The inve

Method of loading drug delivery pack Engineering Village Publication number: US20060020240 Application number: 11181029 Unstandardized application number: 181029 Patent author

United States Patent Application 20030068416 Kind Code A1 Burgess, Wilson ; et al. April 10, 2003 Abstract The present invention relates to an improved method for lyophilization or freez

(12) Patent Application: (11) CA 2199018 ABSTRACT: A method of forming a lyophilized liposome product by combining a lipid with an aqueous solution containing a drying protectant, without addi

United States Patent Application 20050113446 Kind Code A1 Keri, Vilmos ; et al. May 26, 2005 Method of purifying pravastatin Abstract The present invention provides pure pravastatin co

Method of treating mammalian joint maladies by biological fluid transplantation US PATENT & TRADEMARK OFFICE United States Patent Application 20060083787 Kind Code A1 Meader; Charles P. ;

Methods for tailoring the immune response to an antigen or immunogen Engineering Village Publication number: US20060035853 Application number: 11032487 Unstandardized application num

United States Patent Application 20050123918 Kind Code A1 Carroll, Miles ; et al. June 9, 2005 Mhc class I peptide epitopes from the human 5t4 tumor-associated antigen Abstract There i

United States Patent Application 20050037085 Kind Code A1 Jones, David Hugh ; et al. February 17, 2005 Microencapsulated DNA for vaccination and gene therapy Abstract A microparticle c

United States Patent Application 20030104068 Kind Code A1 Mathiowitz, Edith ; et al. June 5, 2003 Abstract A process is provided for making dry, micronized particles of an agent, such as

United States Patent Application 20040043042 Kind Code A1 Johnson, Audrey M. ; et al. March 4, 2004 Abstract Methods and systems are provided for microscale lyophilization or microscale

United States Patent Application 20050154116 Kind Code A1 Nagy, Janos B. ; et al. July 14, 2005 Nanocomposite: products, process for obtaining them and uses thereof Abstract The presen

United States Patent Application 20050142214 Kind Code A1 Brown, Dennis M. June 30, 2005 Naphthalimide compositions and uses thereof Abstract A method of treatment of a host with a cellu

United States Patent Application 20050153888 Kind Code A1 Ronn, Lars Christian ; et al. July 14, 2005 NCAM binding compounds Abstract The invention provides novel compounds which are c

United States Patent Application 20050124589 Kind Code A1 Roessler, Berthold June 9, 2005 New use, pharmaceutical preparations as well as a process for their production Abstract The inve

Non-adhesive elastic gelatin matrices Engineering Village Publication number: US20060068013 Application number: 11152367 Unstandardized application number: 152367 Patent autho

United States Patent Application 20040116345 Kind Code A1 Besman, Marc ; et al. June 17, 2004 Novel albumin-free factor VIII formulations Abstract A Factor VIII composition formulated

United States Patent Application 20050153964 Kind Code A1 Leach, Andrew Colin ; et al. July 14, 2005 Novel compounds Abstract Compounds of formula (I): 1 are inhibitors of the enzyme L

United States Patent Application 20050130978 Kind Code A1 Yuda, Masamichi ; et al. June 16, 2005 Novel crystal of quinoxalinedione derivative anhydride Abstract The object of the prese

United States Patent Application 20050130980 Kind Code A1 Paruch, Kamil ; et al. June 16, 2005 Novel imidazopyrazines as cyclin dependent kinase inhibitors Abstract In its many embodim

US Classification: 435/69.1 CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY MICRO-ORGANISM, TISSUE CELL CULTURE OR ENZYME USING PROCESS TO SYNTHESIZE A DESIRED CHEMICAL COMPOUND OR COMPOSITION

Oral delivery system comprising a drug/polymer complex Engineering Village Publication number: US20050287212 Application number: 148673 Unstandardized application number: 11148673

United States Patent Application 20050106238 Kind Code A1 Wuthrich, Patrick ; et al. May 19, 2005 Orodispersible pharmaceutical composition comprising ivabradine Abstract The invention

United States Patent Application 20050106237 Kind Code A1 Wuthrich, Patrick ; et al. May 19, 2005 Orodispersible pharmaceutical composition comprising perindopril Abstract The inventio

United States Patent Application 20050131071 Kind Code A1 Wuthrich, Patrick ; et al. June 16, 2005 Orodispersible pharmaceutical composition of agomelatine Abstract The invention relat

United States Patent Application 20050153894 Kind Code A1 Zheleva, Daniella I. ; et al. July 14, 2005 p21 peptides Abstract The present invention relates to p21 derived peptides capabl

Passive delivery system diluents mixing and delivery Engineering Village Publication number: US20050277894 Application number: 866434 Unstandardized application number: 10866434

United States Patent Application 20050118597 Kind Code A1 Carroll, Miles ; et al. June 2, 2005 Peptide II Abstract There is provided an MHC class II peptide epitope from 5T4 antigen. I

United States Patent Application 20030099714 Kind Code A1 Dasseux, Jean-Louis May 29, 2003 Abstract The invention relates to the formation of peptide/lipid vesicles and complexes through th

(12) Patent Application: (11) CA 2231682 ABSTRACT: A preparation relating to a PGE1-containing fat emulsion with excellent qualities which is superior to the conventional ones bacteriologicall

United States Patent Application 20050112206 Kind Code A1 Watanabe, Shunsuke ; et al. May 26, 2005 Pharmaceutical composition for oral use with improved absorption Abstract The present

United States Patent Application 20050153999 Kind Code A1 Hu, Mengwei July 14, 2005 Pharmaceutical compositions Abstract Disclosed are pharmaceutical compositions comprising NK.sub.1 Ant

United States Patent Application 20050064028 Kind Code A1 Hegedus, Lajos ; et al. March 24, 2005 Pharmaceutical compositions containing plasma protein Abstract The invention is related

(12) Patent Application: (11) CA 2275153 ABSTRACT: A pharmaceutical composition comprising a nucleotide analogue, mannitol and a modifying additve which is sodium chloride or a polyol which is

United States Patent Application 20050143393 Kind Code A1 Dean, David Kenneth ; et al. June 30, 2005 Pleuromutilin derivatives with antimicrobial activity Abstract Pleuromutilin compou

United States Patent Application 20020120228 Kind Code A1 Maa, Yuh-Fun ; et al. August 29, 2002 Powder compositions Abstract A gel-forming free-flowing powder suitable for use as a vac

United States Patent Application 20040213745 Kind Code A1 Sullivan, Vincent ; et al. October 28, 2004 Powder formulations of rSEB for improved vaccination Abstract A method of preparin

United States Patent Application 20050154004 Kind Code A1 Banwell, Martin Gerhardt ; et al. July 14, 2005 Preparation of fused polycyclic alkaloids by ring closure of azomethine ylides, n

United States Patent Application 20050153018 Kind Code A1 Ubbink, Johan Bernard ; et al. July 14, 2005 Probiotic delivery system Abstract The present invention relates to a probiotic d

United States Patent Application 20030049717 Kind Code A1 Vesey, Graham ; et al. March 13, 2003 Products comprising quantum of bioparticles and method for production thereof Abstract A

United States Patent Application 20050032192 Kind Code A1 Vesey, Graham ; et al. February 10, 2005 Products containing quantum of bioparticles and method for production thereof Abstract

United States Patent Application 20050107365 Kind Code A1 Becker, Cyrus Kephra ; et al. May 19, 2005 Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists Abstract This

Patent number: US2005084530 Publication date: 2005-04-21 Inventor: RAO PAVULURI V (IN); KHADGAPATHI PODILI (IN) Applicant: NATCO PHARMA LTD (IN) Classification: - international: A61K31/48;

United States Patent Application 20050002965 Kind Code A1 Yun, Chae-Ok ; et al. January 6, 2005 Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comp

United States Patent Application 20030202978 Kind Code A1 Maa, Yuh-Fun ; et al. October 30, 2003 Spray freeze-dried compositions Abstract A process for producing a powder comprises spr

United States Patent Application 20040213798 Kind Code A1 Maa, Yuh-Fun ; et al. October 28, 2004 Spray-dried alum compositions Abstract A gel-forming free-flowing powder suitable for u

Stabilization of alum-adjuvanted immunologically active agents Engineering Village Publication number: US20060067943 Application number: 11237200 Unstandardized application number:

United States Patent Application 20050119172 Kind Code A1 Merkle, Werner June 2, 2005 Stabilization of protein preparations Abstract A composition comprising a non-albumin protein is sta

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(12) Patent Application: (11) CA 2140971 ABSTRACT: The present invention provides a freeze dried pharmaceutical composition comprising hirudin and a water-soluble salt of calcium and/or magnes

Stable liquid and lyophilized formulation of proteins Engineering Village Publication number: US20060008415 Application number: 11166906 Unstandardized application number: 166906

(12) Patent Application: (11) CA 2454587 ABSTRACT: This invention is directed to a stable lyophilized pharmaceutical formulation prepared by lyophilizing an aqueous formulation comprising a hi

(12) Patent Application: (11) CA 2135265 ABSTRACT A stable lyophilized composition of the antitumor alkylating agent thiotepa and a method of preparing such a composition via co-lyophilization o

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United States Patent Application 20050153980 Kind Code A1 Schadt, Oliver ; et al. July 14, 2005 Substituted indoles Abstract Substituted indoles of the formula (I) and physiologically

United States Patent Application 20050143290 Kind Code A1 Rademacher, Thomas William ; et al. June 30, 2005 Substituted inositols and their use Abstract Inositol phosphate esters and c

United States Patent Application 20050107382 Kind Code A1 Brown, Alan Daniel ; et al. May 19, 2005 Substituted triazole derivatives as oxytocin antagonists Abstract The present inventi

United States Patent Application 20050084537 Kind Code A1 Martyn, Glen Patrick ; et al. April 21, 2005 Sustained-release compositions Abstract Microparticles comprise a therapeutic age

United States Patent Application 20050131217 Kind Code A1 Tsien, Roger Y. ; et al. June 16, 2005 Synthetic molecules that specifically react with target sequences Abstract The present

(12) Patent Application: (11) CA 2410468 ABSTRACT: A syringe system requires a decreased vertical travel for sealing during a lyophilization process and therefore provides for increased utiliz

Transdermal delivery system for dried particulate or lyophilized medications Engineering Village Publication number: US20060121104 Application number: 11327016 Unstandardized applica

United States Patent Application 20050124646 Kind Code A1 Okuhara, Masakuni ; et al. June 9, 2005 Tricyclo compounds, a process for their production and a pharmaceutical composition conta

United States Patent Application 20040151736 Kind Code A1 Sikora, Christopher A. ; et al. August 5, 2004 Use of cross-protection to identify novel vaccine candidates for infectious agents

USE OF RECOMBINANT OR SYNTHETIC GELATIN-LIKE PROTEINS AS STABILISER IN LYOPHILIZED PHARMACEUTICAL COMPOSITIONS Engineering Village 2 ? 2006 Elsevier Inc Publication number: EP1651275 Appli

United States Patent Application 20050048083 Kind Code A1 Colau, Brigitte Desiree Alberte ; et al. March 3, 2005 Vaccine Abstract The invention provides a method of inducing an immune

United States Patent Application 20030059435 Kind Code A1 Gallili, Gilad ; et al. March 27, 2003 Vaccine composition and method of using the same Abstract The present invention relates

United States Patent Application 20020182226 Kind Code A1 Peetermans, Julien ; et al. December 5, 2002 Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto alum

(12) Patent Application: (11) CA 2178496 ABSTRACT: The present invention relates to a lyophilization process and a cap (10) intended for vials or use therewith for containers that are subjecte