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Lyophilization and Protein Formulation
RNAi Pharmacokinetics - Protein Synthesis

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Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmaco...

Votes:6 Comments:0
Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmacokinetics of Paclitaxel Nov 2005 Anja Henningsson, Sharon Marsh, Walter J. Loos, Mats O. Karlsson, Adam Garsa, Klaus READ MORE
http://clincancerres.aacrjournals.org/cgi/content/full/11/22/8097...

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of an Orally Active...

Votes:23 Comments:0
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of an Orally Active Novel Camptothecin Analog, DRF-1042, in Refractory Cancer Patients in a Phase I Dose Escalation Study Jul 2004 Aran READ MORE
http://jcp.sagepub.com/cgi/content/abstract/44/7/723...

Pharmacokinetic and Pharmacodynamic Analysis of Amprenavir-Containing Combinatio...

Votes:18 Comments:0
Pharmacokinetic and Pharmacodynamic Analysis of Amprenavir-Containing Combination Therapy in HIV-1-Infected Children Nov 2004 Daniel S. Stein, Yu Lou, Mark Johnson, Sharon Randall, Stephane Blanch READ MORE
http://jcp.sagepub.com/cgi/content/full/44/11/1301...

Pharmacokinetics of Paclitaxel in Ovarian Cancer Patients and Genetic Polymorphi...

Votes:31 Comments:0
Pharmacokinetics of Paclitaxel in Ovarian Cancer Patients and Genetic Polymorphisms of CYP2C8, CYP3A4, and MDR1 Jun 2005 Miki Nakajima, Yuto Fujiki, Satoru Kyo, Taro Kanaya, Mitsuhiro Nakamura, Yo READ MORE
http://jcp.sagepub.com/cgi/content/full/45/6/674

Discordance Between N-acetyltransferase 2 Phenotype and Genotype in a Population...

Votes:7 Comments:0
Discordance Between N-acetyltransferase 2 Phenotype and Genotype in a Population of Hmong Subjects Jul 2006 Robert J. Straka, R. Todd Burkhardt, Nicholas P. Lang, Kelly Z. Hadsall, and Michael Y. READ MORE
http://jcp.sagepub.com/cgi/content/full/46/7/802...

The Effects of Ergoloid Mesylates and Ginkgo Biloba on the Pharmacokinetics of T...

Votes:20 Comments:0
The Effects of Ergoloid Mesylates and Ginkgo Biloba on the Pharmacokinetics of Ticlopidine Jun 2006 Wen-Jen Lu, Jin-ding Huang, and Ming-Liang Lai Journal of Clinical Pharmacology Abstract Ticl READ MORE
http://jcp.sagepub.com/cgi/reprint/46/6/628...

Evaluation of the Drug Interaction Potential of Aplaviroc, a Novel Human Immunod...

Votes:15 Comments:0
Evaluation of the Drug Interaction Potential of Aplaviroc, a Novel Human Immunodeficiency Virus Entry Inhibitor, Using a Modified Cooperstown 5 + 1 Cocktail May 2006 Brendan M. Johnson, Ivy H. Son READ MORE
http://jcp.sagepub.com/cgi/content/full/46/5/577...

Altered Methylprednisolone Pharmacodynamics in Healthy Subjects With Histamine N...

Votes:10 Comments:0
Altered Methylprednisolone Pharmacodynamics in Healthy Subjects With Histamine N-Methyltransferase C314T Genetic Polymorphism Apr 2006 Yuen Yi Hon, William J. Jusko, Vicky E. Spratlin, and Michael READ MORE
http://jcp.sagepub.com/cgi/content/full/46/4/408...

G2677T and C3435T Genotype and Haplotype Are Associated With Hepatic ABCB1 (MDR1...

Votes:23 Comments:0
G2677T and C3435T Genotype and Haplotype Are Associated With Hepatic ABCB1 (MDR1) Expression Mar 2006 Pengfei Song, Jatinder K. Lamba, Lijun Zhang, Erin Schuetz, Nikhil Shukla, Bernd Meibohm, and READ MORE
http://jcp.sagepub.com/cgi/content/full/46/3/373...

The Effect of Oral Pleconaril on Hepatic Cytochrome P450 3A Activity in Healthy ...

Votes:18 Comments:0
The Effect of Oral Pleconaril on Hepatic Cytochrome P450 3A Activity in Healthy Adults Using Intravenous Midazolam as a Probe Jan 2006 Joseph D. Ma, Anne N. Nafziger, Gerry Rhodes, Siyu Liu, Anne READ MORE
http://jcp.sagepub.com/cgi/content/full/46/1/103...

Ascending Multiple-Dose Pharmacokinetics of Viramidine, a Prodrug of Ribavirin, ...

Votes:32 Comments:0
Ascending Multiple-Dose Pharmacokinetics of Viramidine, a Prodrug of Ribavirin, in Adult Subjects With Compensated Hepatitis C Infection Mar 2005 Sanjee Aora, Christine Xu, Alice Teng, Janet Peter READ MORE
http://jcp.sagepub.com/cgi/content/full/45/3/275...

Challenges and opportunities of pharmacogenetics in drug development

Votes:25 Comments:0
Challenges and opportunities of pharmacogenetics in drug development May 2006 Ruth March Future Medicine Drugs fail the regulatory process for a variety of reasons, including issues with pharmac READ MORE
http://www.futuremedicine.com/doi/abs/10.2217/17410541.3.2.195
RNAi Pharmacokinetics - Protein Synthesis
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