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Lyophilization and Protein Formulation
Lyophilization Articles & Reports

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A history of lyophilization in pharmaceutical applications: control and monitori...
Votes:9 Comments:0
A history of lyophilization in pharmaceutical applications: control and monitoring, accuracy, and reproducibility continue to define the lyophilization process, thus enhancing product aesthetics, stab READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_2_28/ai_113416745

Effect of freezing rates and excipients on the infectivity of a live viral vacci...
Votes:34 Comments:0
Effect of freezing rates and excipients on the infectivity of a live viral vaccine during lyophilization Jul-Aug 2004 By: Zhai S, Hansen RK, Taylor R, Skepper JN, Sanches R, Slater NK - Department READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The nonsteady state modeling of freeze drying: in-process product temperature an...
Votes:9 Comments:0
The nonsteady state modeling of freeze drying: in-process product temperature and moisture content mapping and pharmaceutical product quality applications. Date: 2005 By: Pikal MJ, Cardon S, Bhugr READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The effects of lyophilization on the stability of liposomes containing 5-FU
Votes:17 Comments:0
The effects of lyophilization on the stability of liposomes containing 5-FU March 2005 By: Glavas-Dodov M, Fredro-Kumbaradzi E, Goracinova K, Simonoska M, Calis S, Trajkovic-Jolevska S, Hincal AA - READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Immobilization of nonviral vectors during the freezing step of lyophilization
Votes:12 Comments:0
Immobilization of nonviral vectors during the freezing step of lyophilization Nov 2004 By: Armstrong TK, Anchordoquy TJ - Department of Pharmaceutical Sciences, University of Colorado, Denver, Colo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Freeze drying--principles and practice for successful scale-up to manufacturing
Votes:26 Comments:0
Freeze drying--principles and practice for successful scale-up to manufacturing August 2004 By: Merck Research Laboratories, Merck & Co. Inc., Sumneytown Pike WP78-204, West Point, PA 19486 PubMed READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

How to Evaluate a Publication on Lyophilization/Freeze Drying
Votes:32 Comments:0
How to Evaluate a Publication on Lyophilization/Freeze Drying August 2003 Insight For those of us who are experienced in this field, and perhaps already have a well established view on the subject, READ MORE
http://www.phase-technologies.com/html/vol._6_no._8.html

Lyophilization Does Not Inactivate Infectious Retrovirus in Systemically Infecte...
Votes:26 Comments:0
Lyophilization Does Not Inactivate Infectious Retrovirus in Systemically Infected Bone and Tendon Allografts March 11, 2004 Matthew J. Crawford, DO, PhD, Cheryl L. Swenson, DVM, PhD, Steven P. Arno READ MORE
http://ajsm.highwire.org/cgi/content/short/0363546504263404v1

Raffinose crystallization during freeze-drying and its impact on recovery of pro...
Votes:40 Comments:0
Raffinose crystallization during freeze-drying and its impact on recovery of protein activity. 2005 Feb Chatterjee K, Shalaev EY, Suryanarayanan R. PubMed PURPOSE: To study i) phase transitions in READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

A Simple Method for Estimating Respiratory Solute Dilution in Exhaled Breath Con...
Votes:35 Comments:0
A Simple Method for Estimating Respiratory Solute Dilution in Exhaled Breath Condensates December 15, 2003 Effros, Richard M, Biller, Julie, Foss, Bradley, Hoagland, Kelly, Et al American Journ READ MORE
http://www.findarticles.com/p/articles/mi_qa4085/is_200312/ai_n9329958

The saga of freeze-drying: through recognized by the public since free-dried cof...
Votes:9 Comments:0
The saga of freeze-drying: through recognized by the public since free-dried coffee hit the market 30 years ago, lyophilization remains far from mature and deserves more research Feb, 2004 by Louis READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_2_28/ai_113416739

Freeze-drying capabilities
Votes:3 Comments:0
Freeze-drying capabilities Dec, 2004 Pharmaceutical Technology Lyophilization Technology offers capabilities for highly potent compounds, oncology therapeutics, and biologicals requiring BL2 cont READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_12_28/ai_n8694012

Lyophilization
Votes:34 Comments:0
Lyophilization Apri 25, 2004 By Narlin B. Beaty, Ph.D. Chesapeake Biological Laboratories, Inc. Please visit the web site to view the article in its entirety. Elementary lyophilization involves t READ MORE
http://www.cblinc.com/Assets/Documents/Publications/Beaty%20Lyo%20Work...

Lyophilization of Unit Dose Pharmaceutical Dosage Forms
Votes:28 Comments:0
Lyophilization of Unit Dose Pharmaceutical Dosage Forms May 12, 2003 By P. Thapa; A. J. Baillie; H. N. E. Stevens Drug Development and Industrial Pharmacy? , Volume 29 , Issue 5 You can vie READ MORE
http://taylorandfrancis.metapress.com./app/home/contribution.asp...

Freeze-drying of pharmaceuticals in vials on trays: effects of drying chamber wa...
Votes:23 Comments:0
Freeze-drying of pharmaceuticals in vials on trays: effects of drying chamber wall temperature and tray side on lyophilizationnext term performance April 2005 By K.H. Gan, R. Bruttini, O.K. Crosser READ MORE
http://www.sciencedirect.com/science...

The ophthalmic lyophilisate carrier system (OLCS): development of a novel dosage...
Votes:31 Comments:0
The ophthalmic lyophilisate carrier system (OLCS): development of a novel dosage form, freeze-drying technique, and in vitro quality control tests March 2004 By Richard S?verkr?p , Sabine Grunthal , READ MORE
http://www.sciencedirect.com/science...

Optimisation of initial cell concentration enhances freeze-drying tolerance of P...
Votes:39 Comments:0
Optimisation of initial cell concentration enhances freeze-drying tolerance of Pseudomonas chlororaphis August 2003 By Johan Palmfeldt, Peter R?dstr?m and B?rbel Hahn-H?gerdal Cryobiology, Volume 4 READ MORE
http://www.sciencedirect.com/science...

Lyophilization of polyethylene glycol mixtures
Votes:15 Comments:0
Lyophilization of polyethylene glycol mixtures June 2004 By Ketan Amin, Rose-Marie Dannenfelser, Joseph Zielinski, Barbara Wang Journal of Pharmaceutical Sciences Please visit the web site to view READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109084547/ABSTRACT

Raman spectroscopic characterization of drying-induced structural changes in a t...
Votes:29 Comments:0
Raman spectroscopic characterization of drying-induced structural changes in a therapeutic antibody: Correlating structural changes with long-term stability January 30, 2004 By Sane SU, Wong R, Hsu READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/107583963/ABSTRACT

Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mix...
Votes:23 Comments:0
Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mixture of water and tertiary butyl alcohol as solvent January 6, 2004 By D.J. Van Drooge, W.L.J. Hinrichs, H.W. Frijlink READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/106598026/ABSTRACT

Development and characterization of a novel liposome-based formulation of SN-38
Votes:37 Comments:0
Development and characterization of a novel liposome-based formulation of SN-38 February 11, 2004 By J. Allen Zhang, Tong Xuan, Manjeet Parmar, Lan Ma, Sydney Ugwu, Shahid Ali and Imran Ahmad Inter READ MORE
http://www.sciencedirect.com/science...

Orally fast disintegrating tablets: developments, technologies, taste-masking an...
Votes:13 Comments:0
Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies. 2004 By Fu Y, Yang S, Jeong SH, Kimura S, Park K. Critical Review Therapeutic Drug Carrier Syst. READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs.
Votes:7 Comments:0
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs. January 2004 By Loftsson T, Sigurdsson HH, Masson M, Schipper N. Pharmazie You can view the abstract online. A subscrip READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Slow release of two antibiotics of veterinary interest from PVA hydrogels
Votes:21 Comments:0
Slow release of two antibiotics of veterinary interest from PVA hydrogels January 2004 By A. Moretto, L. Tesolin, F. Marsilio, M. Schiavon, M. Berna and F. M. Veronese Il Farmaco You can view th READ MORE
http://www.sciencedirect.com/science...

Culture of primary rat hepatocytes within porous chitosan scaffolds
Votes:34 Comments:0
Culture of primary rat hepatocytes within porous chitosan scaffolds October 2003 By Li J, Pan J, Zhang L, Guo X, Yu Y. Journal of Biomedical Materials Research Part A Please visit the web site to READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/106560128/ABSTRACT

A freeze-dried fibrin disc as a biodegradable drug release matrix
Votes:10 Comments:0
A freeze-dried fibrin disc as a biodegradable drug release matrix March 2004 By T. R. Santhosh Kumar , Mary Vasantha Bai and Lissy K. Krishnan Biologicals Volume 32, Issue 1 You can view the abstr READ MORE
http://www.sciencedirect.com/science...

Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate...
Votes:24 Comments:0
Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate copolymer nanoparticles February 16, 2005 By Yung-Chih Kuo International Journal of Pharmace READ MORE
http://www.sciencedirect.com/science...

A new polysaccharidic gel matrix for drug delivery: preparation and mechanical p...
Votes:37 Comments:0
A new polysaccharidic gel matrix for drug delivery: preparation and mechanical properties Received 21 July 2004; accepted 25 October 2004. Available online 24 November 2004. Tommasina Covielloa, READ MORE
http://www.sciencedirect.com/science...

The improved dissolution and prevention of ampoule breakage attained by the intr...
Votes:32 Comments:0
The improved dissolution and prevention of ampoule breakage attained by the introduction of pretreatment into the production process of the lyophilized formulation of recombinant human Interleukin-11 READ MORE
http://www.sciencedirect.com/science...

Pharmaceutical development of a parenteral lyophilized formulation of the invest...
Votes:7 Comments:0
Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280. 2003 Oct Bouma M, Nuijen B, Harms R, Rice JR, Nowotnik READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Investigation of freeze?drying sublimation rates using a freeze?drying microbala...
Votes:40 Comments:0
Investigation of freeze?drying sublimation rates using a freeze?drying microbalance technique July 2004 By Jun Xiang, Jeffery M. Hey, Volker Liedtke and D. Q. Wang International Journal of Pharmace READ MORE
http://www.sciencedirect.com/science...

Collagen/PLGA microparticle composites for local controlled delivery of gentamic...
Votes:10 Comments:0
Collagen/PLGA microparticle composites for local controlled delivery of gentamicin Published Online: 26 Aug 2003 Received: 1 August 2002; Revised: 14 April 2003; Accepted: 14 April 2003 Monika Schl READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/104556356/ABSTRACT

Preservation mechanisms of trehalose in food and biosystems
Votes:5 Comments:0
Preservation mechanisms of trehalose in food and biosystems 10 February 2005 Available online 17 June 2004 Alex Patist, and Hans Zoerb Colloids and Surfaces B: Biointerfaces Volume 40, Issue 2 READ MORE
http://www.sciencedirect.com/science...

Synthesis of Nanosized Chitosan-Poly(acrylic acid) Particles by a Dropping Metho...
Votes:19 Comments:0
Synthesis of Nanosized Chitosan-Poly(acrylic acid) Particles by a Dropping Method Published Online: 13 Apr 2004 Received: 22 October 2003; Revised: 9 February 2004; Accepted: 18 February 2004 Tao-C READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/108066869/ABSTRACT

Influenza vaccine powder formulation development: spray-freeze-drying and stabil...
Votes:32 Comments:0
Influenza vaccine powder formulation development: spray-freeze-drying and stability evaluation Published Online: 12 May 2004 Received: 13 January 2004; Revised: 20 February 2004; Accepted: 15 March READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/108564988/ABSTRACT

Polymeric drug carriers functionalized with pairwise arranged hydroxyl and/or ca...
Votes:8 Comments:0
Polymeric drug carriers functionalized with pairwise arranged hydroxyl and/or carboxyl groups for platinum chelation April 5, 2005 By Mark T. Johnson, Lionel L. Komane, David D. Nprimeda, Eberhard READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109876487/ABSTRACT

Partially crystalline systems in lyophilization: II. Withstanding collapse at hi...
Votes:40 Comments:0
Partially crystalline systems in lyophilization: II. Withstanding collapse at high primary drying temperatures and impact on protein activity recovery April 2005 By Koustuv Chatterjee, Evgenyi Y Sh READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109930092/ABSTRACT

Heat Stability of the Lyophilized Sabin Poliovaccine
Votes:16 Comments:0
Heat Stability of the Lyophilized Sabin Poliovaccine Received February 26, 2003. Accepted May 1, 2003 Hiroshi Shiomi, Tomoko Urasawa*1 and Shozo Urasawa* Japanese Journal of Infectious Diseases De READ MORE
http://www.nih.go.jp/JJID/56/70.html

Effect of polymer size and cosolutes on phase separation of poly(vinylpyrrolidon...
Votes:11 Comments:0
Effect of polymer size and cosolutes on phase separation of poly(vinylpyrrolidone) (PVP) and dextran in frozen solutions April 2005 By Ken-ichi Izutsu, Nobuo Aoyagi, Shigeo Kojima Journal of Pharm READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109882865/ABSTRACT

Using an Electronic Tongue to Optimize Taste-Masking in a Lyophilized Orally Dis...
Votes:5 Comments:0
Using an Electronic Tongue to Optimize Taste-Masking in a Lyophilized Orally Disintegrating Tablet Formulation 2004 Owen J. Murray,* Wenbin Dang, and David Bergstrom Pharmaceutical Technology Maki READ MORE
http://www.pharmtech.com/pharmtech/article/articleDetail.jsp...

Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-rece...
Votes:19 Comments:0
Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations February 2005 By Shouvik Roy, Rose Jung, Bruce A. Kerwin, T READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109860076/ABSTRACT

Low-Temperature Thermal Analyses are Key to Formulation Design
Votes:14 Comments:0
Low-Temperature Thermal Analyses are Key to Formulation Design 2004 Michael Thomas and Anthony J.Cannon Pharmaceutical Technology Product and process development of a lyophilized preparation is a READ MORE
http://www.pharmtech.com/pharmtech/article/articleDetail.jsp...

Glass transition-related changes in molecular mobility below glass transition te...
Votes:27 Comments:0
Glass transition-related changes in molecular mobility below glass transition temperature of freeze-dried formulations, as measured by dielectric spectroscopy and solid state nuclear magnetic resonanc READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109801313/ABSTRACT

Characterization and crystal structure of D-mannitol hemihydrate
Votes:3 Comments:0
Characterization and crystal structure of D-mannitol hemihydrate September 2004 By Cletus Nunes, Raj Suryanarayanan, Cristian E. Botez, Peter W. Stephens Journal of Pharmaceutical Sciences, Volume READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109617363/ABSTRACT

Radiopharmaceutical development of a freeze-dried kit formulation for the prepar...
Votes:11 Comments:0
Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis July 2004 By Elisabeth READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109580933/ABSTRACT

Stabilization of rasburicase and physico-chemical characterization of the result...
Votes:25 Comments:0
Stabilization of rasburicase and physico-chemical characterization of the resulting injectable formulation. September 2004 By Bayol A, Breul T, Dupin P, Menegotto J, Aleman C, Duplaa H, Faure P, Bon READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Assessment of degree of disorder (amorphicity) of lyophilized formulations of gr...
Votes:38 Comments:0
Assessment of degree of disorder (amorphicity) of lyophilized formulations of growth hormone using isothermal microcalorimetry. May 2004 By Mosharraf M. Drug Development and Industrial Pharmacy Yo READ MORE
http://www.dekker.com/servlet/product/DOI/101081DDC120037472;DekkerSes...

Evaluation of extrusion/spheronisation, layering and compaction for the preparat...
Votes:14 Comments:0
Evaluation of extrusion/spheronisation, layering and compaction for the preparation of an oral, multi-particulate formulation of viable, hIL-10 producing Lactococcus lactis January 2005 By Huyghebae READ MORE
http://www.sciencedirect.com/science...

Preformulation study of the inclusion complex warfarin-?-cyclodextrin
Votes:8 Comments:0
Preformulation study of the inclusion complex warfarin-?-cyclodextrin March 2005 By Zingone G, Rubessa F. International Journal of Pharmaceutics, Volume 291, Issues 1-2 , 3 March 2005, Pages 3-10 READ MORE
http://www.sciencedirect.com/science...

Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nan...
Votes:22 Comments:0
Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nanodispersion. A comparative study November 2003 By Schaffazick SR, Pohlmann AR, Dalla-Costa T, Guterres SS. European J READ MORE
http://www.sciencedirect.com/science...

Pharmaceutical development of a lyophilised dosage form for the investigational ...
Votes:36 Comments:0
Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent 2005 By Monique W.J. Den Brok, READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Partially crystalline systems in lyophilization: I. Use of ternary state diagram...
Votes:30 Comments:0
Partially crystalline systems in lyophilization: I. Use of ternary state diagrams to determine extent of crystallization of bulking agent April 2005 By Koustuv Chatterjee, Evgenyi Y. Shalaev, Raj Su READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Oral Vaccination of Captive Arctic Foxes with Lyophilized SAG2 Rabies Vaccine
Votes:19 Comments:0
Oral Vaccination of Captive Arctic Foxes with Lyophilized SAG2 Rabies Vaccine 2004 Erich H. Follmann1,3, Donald G. Ritter2 and Donald W. Hartbauer1 Journal of Wildlife Diseases, 40(2), 2004, pp. 3 READ MORE
http://www.jwildlifedis.org/cgi/content/abstract/40/2/328

High yields of stable and highly pure nucleocapsid proteins of different hantavi...
Votes:14 Comments:0
High yields of stable and highly pure nucleocapsid proteins of different hantaviruses can be generated in the yeast 5 August 2004 Received 16 October 2003; Revised 14 April 2004; accepted 30 Apri READ MORE
http://www.sciencedirect.com/science...

Evaluation of the xerovac process for the preparation of heat tolerant contagiou...
Votes:9 Comments:0
Evaluation of the xerovac process for the preparation of heat tolerant contagious bovine pleuropneumonia (CBPP) vaccine 8 April 2005 Received 23 April 2004; accepted 10 November 2004. Available on READ MORE
http://www.sciencedirect.com/science...

Comparative efficacy of various chemical stabilizers on the thermostability of a...
Votes:3 Comments:0
Comparative efficacy of various chemical stabilizers on the thermostability of a live-attenuated peste des petits ruminants (PPR) vaccine 1 December 2003 Received 20 February 2003; accepted 26 Jun READ MORE
http://www.sciencedirect.com/science...

Crystallization of Cephalothin Sodium During Lyophilization from tert-Butyl Alco...
Votes:31 Comments:0
Crystallization of Cephalothin Sodium During Lyophilization from tert-Butyl Alcohol?Water Cosolvent System Chitra Telang, and Raj Suryanarayanan 1 January 2005 Springer Science+Business Media B.V. READ MORE
http://www.springerlink.com/app/home/contribution.asp...

On the relationship between conformation and stability in solid pharmaceutical p...
Votes:25 Comments:0
On the relationship between conformation and stability in solid pharmaceutical protein formulations Alexander M. Klibanov and Jennifer A. Schefiliti July 2004 Springer Science+Business Media B.V. READ MORE
http://www.springerlink.com/app/home/contribution.asp...

Statistical Evaluation of Vial Design Features That Influence Sublimation Rates ...
Votes:39 Comments:0
Statistical Evaluation of Vial Design Features That Influence Sublimation Rates During Primary Drying Anthony Cannon and Kerryann Shemeley March 2004 Springer Science+Business Media B.V., Formerl READ MORE
http://www.springerlink.com/app/home/contribution.asp...

In-Situ Near-Infrared Spectroscopy Monitoring of the Lyophilization Process
Votes:15 Comments:0
In-Situ Near-Infrared Spectroscopy Monitoring of the Lyophilization Process Mikael Br?lls , Staffan Folestad, Anders Spar?n and Anders Rasmuson March 2003 Springer Science+Business Media B.V., For READ MORE
http://www.springerlink.com/app/home/contribution.asp...

Effect of pre-freezing temperature and lyophilizer shelf temperature on recovery...
Votes:9 Comments:0
Effect of pre-freezing temperature and lyophilizer shelf temperature on recovery of red blood cells after lyophilization Zhongguo Shi Yan Xue Ye Xue Za Zhi June 1, 2004 HighWire Press To study eff READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15228669...

Correlation between the cellular content of mobile water and the viability of ly...
Votes:17 Comments:0
Correlation between the cellular content of mobile water and the viability of lyophilized yeast cells AN Shkidchenko and VA Nikitin July 1, 2004 HighWire Press Spin-echo NMR studies showed that ly READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15521178...

Effect of freezing rate on physical stability of lyophilized cationic liposomes
Votes:12 Comments:0
Effect of freezing rate on physical stability of lyophilized cationic liposomes Y Aso and S Yoshioka March 1, 2005 HighWire Press Factors affecting the storage stability of lyophilized cationic li READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15744102...

Usefulness of lyophilized calibration plasmas for International Normalized Ratio...
Votes:25 Comments:0
Usefulness of lyophilized calibration plasmas for International Normalized Ratio determination with the bovine combined thromboplastin (Thrombotest): results of a collaborative study Veena Chantarang READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15741805...

Freeze-drying of silymarin-loaded solid lipid nanoparticles
Votes:39 Comments:0
Freeze-drying of silymarin-loaded solid lipid nanoparticles J He, JF Feng, LL Zhang, WG Lu, and SX Hou January 1, 2005 HighWire Press OBJECTIVE: To investigate lyophilization of SM-SLN. METHOD: Th READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15714812...

A case for the streamlined procedure
Votes:34 Comments:0
A case for the streamlined procedure Julian Hitchcock 21 March 2005 Mills & Reeve A recent swift conclusion to a patent claim in the Court of Appeal could herald more patent litigation in the UK, READ MORE
http://www.cambridgenetwork.co.uk/POOLED/ARTICLES/BF_NEWSART/VIEW.ASP....

Theoretical prediction of ?optimal? freezing programmes
Votes:29 Comments:0
Theoretical prediction of ?optimal? freezing programmes H. Woelders, and A. Chaveiro 8 December 2004 Elsevier Inc. Abstract We have developed a quantitative description of the osmotic behaviour READ MORE
http://www.sciencedirect.com/science...

Freeze drying could improve supply of stems cells and platelets
Votes:23 Comments:0
Freeze drying could improve supply of stems cells and platelets Department of Chemical Engineering Spring/Summer 2003 If you freeze one million embryonic stem cells, less than one percent will sur READ MORE
http://www.engr.wisc.edu/che/newsletter/2003_springsummer/Article02_st...

Freeze-drying of mononuclear cells and whole blood of human cord blood
Votes:18 Comments:0
Freeze-drying of mononuclear cells and whole blood of human cord blood Xiao H-H.; Hua T-C.; Li J.; Gu X-L.; Wang X.; Wu Z-J.; Meng L.; Gao Q-R.; Chen J.; Gong Z-P. 1 February 2004 Cryoletters Abs READ MORE
http://www.ingentaconnect.com/content/cryo/cryo/2004/00000025/00000002...

Antioxidative properties of lactoferrin from bovine colostrum before and after i...
Votes:13 Comments:0
Antioxidative properties of lactoferrin from bovine colostrum before and after its lyophilization September 2003 Sandomirsky B.P.; Galchenko S.E.; Galchenko K.S. Ingentaconnect Abstract: The ef READ MORE
http://www.ingentaconnect.com/content/cryo/cryo/2003/00000024/00000005...

Electron Tomographic Analysis of Somatic Cell Plate Formation in Meristematic Ce...
Votes:27 Comments:0
Electron Tomographic Analysis of Somatic Cell Plate Formation in Meristematic Cells of Arabidopsis Preserved by High-Pressure Freezing January 28, 2004 Jos? M. Segu?-Simarro, Jotham R. Austin, II, E READ MORE
http://www.pubmedcentral.gov/articlerender.fcgi...

Long-Term Preservation of Fungal Isolates in Commercially Prepared Cryogenic Mic...
Votes:21 Comments:0
Long-Term Preservation of Fungal Isolates in Commercially Prepared Cryogenic Microbank Vials 2004 March A. Espinel-Ingroff, D. Montero,and E. Martin-Mazuelos PubMed Abstract Since 1994, 6,198 yea READ MORE
http://www.pubmedcentral.gov/articlerender.fcgi...

Tolerance of the Mouse Sperm Nuclei to Freeze-Drying Depends on Their Disulfide ...
Votes:35 Comments:0
Tolerance of the Mouse Sperm Nuclei to Freeze-Drying Depends on Their Disulfide Status July 29, 2003 Takehito Kaneko , David G. Whittingham , James W. Overstreet , and Ryuzo Yanagimachi Biology of READ MORE
http://www.biolreprod.org/cgi/content/short/biolreprod.103.019729v1

Possibility of Long-Term Preservation of Freeze-Dried Mouse Spermatozoa1
Votes:10 Comments:0
Possibility of Long-Term Preservation of Freeze-Dried Mouse Spermatozoa1 November 3, 2004 Yosuke Kawase, Hiroshi Araya, Nobuo Kamada, Kou-ichi Jishage and Hiroshi Suzuki Biology of Reproduction F READ MORE
http://www.biolreprod.org/cgi/content/abstract/72/3/568

Activation, Pronuclear Formation, and Development In Vitro of Pig Oocytes Follow...
Votes:24 Comments:0
Activation, Pronuclear Formation, and Development In Vitro of Pig Oocytes Following Intracytoplasmic Injection of Freeze-Dried Spermatozoa June 23, 2004 In-Kiu Kwon, Ki-Eun Park and Koji Niwa Biolo READ MORE
http://www.biolreprod.org/cgi/content/abstract/71/5/1430

Freeze-Dried Sperm Fertilization Leads to Full-Term Development in Rabbits
Votes:38 Comments:0
Freeze-Dried Sperm Fertilization Leads to Full-Term Development in Rabbits February 11, 2004 Ji-Long Liu, Hirokazu Kusakabe, Ching-Chien Chang, Hiroyuki Suzuki, David W. Schmidt, Marina Julian, Robe READ MORE
http://www.biolreprod.org/cgi/content/abstract/70/6/1776

Patheon leads Europe In Lyophilization
Votes:27 Comments:0
Patheon leads Europe In Lyophilization 10/28/2003 Pharmaceutical Online Canada-headquartered contract manufacturing company Patheon is now offering the largest capacity in Europe for Lyophilisati READ MORE
http://www.pharmaceuticalonline.com/content/news/article.asp...

A novel method for the preparation of liposomes: Freeze drying of monophase solu...
Votes:11 Comments:0
A novel method for the preparation of liposomes: Freeze drying of monophase solutions June 2004 Chunlei Li, Yingjie Deng, Journal of Pharmaceutical Sciences You can view the abstract online. A su READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Uniform encapsulation of stable protein nanoparticles produced by spray freezing...
Votes:5 Comments:0
Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release January 2004 W. Thomas Leach, Dale T. Simpson, Tibisay N. Val, Efemona C. Anuta, Z READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Effect of collapse on the stability of freeze-dried recombinant factor VIII and ...
Votes:19 Comments:0
Effect of collapse on the stability of freeze-dried recombinant factor VIII and a-amylase May 2004 D.Q. Wang, J.M. Hey, S.L. Nail Journal of Pharmaceutical Sciences You can view the abstract onlin READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Heat and Mass Transfer Scale-up Issues during Freeze Drying: II. Control and Cha...
Votes:33 Comments:0
Heat and Mass Transfer Scale-up Issues during Freeze Drying: II. Control and Characterization of the Degree of Supercooling August 2004 Shailaja Rambhatla, Roee Ramot, Chandan Bhugra, and Michael J. READ MORE
http://www.aapspharmscitech.org/articles/pt0504/pt050458/pt050458.pdf

Freeze-Drying of Proteins from a Sucrose-Glycine Excipient System: Effect of For...
Votes:8 Comments:0
Freeze-Drying of Proteins from a Sucrose-Glycine Excipient System: Effect of Formulation Composition on Initial Recovery of Protein Activity February 2005 Wei Liu, D.Q. Wang, and Steven L. Nail AAP READ MORE
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Freeze-drying of protein pharmaceuticals: the application of thermal analysis
Votes:22 Comments:0
Freeze-drying of protein pharmaceuticals: the application of thermal analysis November 2004 Vicky P. Kett; Debra McMahon; Kevin Ward Cryoletters You can view the abstract online. A subscription i READ MORE
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Effect of pH, Counter Ion, and Phosphate Concentration on the Glass Transition T...
Votes:35 Comments:0
Effect of pH, Counter Ion, and Phosphate Concentration on the Glass Transition Temperature of Freeze-Dried Sugar-Phosphate Mixtures September 2004 Satoshi Ohtake, Carolina Schebor, Sean P. Palecek, READ MORE
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Protein Powders for Encapsulation: A Comparison of Spray-Freeze Drying and Spray...
Votes:30 Comments:0
Protein Powders for Encapsulation: A Comparison of Spray-Freeze Drying and Spray Drying of Darbepoetin Alfa March 2004 Nguyen X.C.; Herberger J.D.; Burke P.A. Pharmaceutical Research You can view READ MORE
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Lyoprotection of aviscumine with low molecular weight dextrans
Votes:38 Comments:0
Lyoprotection of aviscumine with low molecular weight dextrans April 2003 O. Gloger, K. Witthohn and B. W. M?ller International Journal of Pharmaceutics Volume 260, Issue 1, 9 You can view the a READ MORE
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Brazil opens microbe bank for bioprospectors
Votes:25 Comments:0
Brazil opens microbe bank for bioprospectors 14 March 2005 Wagner de Oliveira SciDevNet [RIO DE JANEIRO] Hundreds of bacteria, fungi and yeast species, mostly collected from the wilds of Brazil, h READ MORE
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Freeze drying could improve supply of stems cells and platelets
Votes:39 Comments:0
Freeze drying could improve supply of stems cells and platelets Spring/Summer 2003 On These Foundations If you freeze one million embryonic stem cells, less than one percent will survive, say Profe READ MORE
http://www.engr.wisc.edu/che/newsletter/2003_springsummer/Article02_st...

Shell freezer offers efficiency and convenience
Votes:33 Comments:0
Shell freezer offers efficiency and convenience February 8, 2005 LaboratoryTalk The VirTis benchtop shell bath is a self-contained, compact freezing unit designed for the preparation of flask sampl READ MORE
http://www.laboratorytalk.com/news/bop/bop107.html

Freeze-dried sugar helps keep heat-sensitive, protein-based drugs working at roo...
Votes:28 Comments:0
Freeze-dried sugar helps keep heat-sensitive, protein-based drugs working at room temperature June 23, 2004 Medical Science News A spoonful of sugar may help the medicine go down, but it may take o READ MORE
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Assure Batch Uniformity for Freeze-Dried Products
Votes:3 Comments:0
Assure Batch Uniformity for Freeze-Dried Products March 2005 By Edward H. Trappler, President, Lyophilization Technology PharmaManufacturing.com Success requires precise control of process condit READ MORE
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Baxter Tackles Insoluble Solutions
Votes:36 Comments:0
Baxter Tackles Insoluble Solutions April/May 2004 Agnes Shanley, Editor in Chief Pharmaceutical Manufacting After less than three years in the contract manufacturing business, Baxter Pharmaceutica READ MORE
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Fill 'Em Up
Votes:31 Comments:0
Fill 'Em Up January 2004 By Angelo De Palma, Ph.D., Contributing Editor PharmaManufacturing.com Because pharmaceutical filling bridges the huge gap between bulk manufacture and distribution, ever READ MORE
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Light scattering investigations on freeze-dried glucocorticoids in aqueous solut...
Votes:6 Comments:0
Light scattering investigations on freeze-dried glucocorticoids in aqueous solution February 2003 By Sven Clau?en, Martin Janich and Reinhard Neubert International Journal of Pharmaceutics You c READ MORE
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Effects of sodium tetraborate and boric acid on nonisothermal mannitol crystalli...
Votes:39 Comments:0
Effects of sodium tetraborate and boric acid on nonisothermal mannitol crystallization in frozen solutions and freeze-dried solids April 2004 Ken-ichi Izutsu , Shemaine O. Ocheda , Nobuo Aoyagi and READ MORE
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Hyaluronan is a key component in cryoprotection and formulation of targeted unil...
Votes:17 Comments:0
Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes 2 May 2003 Received 26 November 2002; revised 14 February 2003; accepted 19 March 2003. ; Availabl READ MORE
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Lipophilic Arabinofuranosyl Cytosine Derivatives in Liposomes
Votes:12 Comments:0
Lipophilic Arabinofuranosyl Cytosine Derivatives in Liposomes Available online 21 February 2005. Reto Schwendener and Herbert Schott Methods in Enzymology Volume 391 , 2005, Pages 58-70 Scie READ MORE
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Examination of aqueous oxidized cellulose dispersions as a potential drug carrie...
Votes:39 Comments:0
Examination of aqueous oxidized cellulose dispersions as a potential drug carrier. II. In vitro and in vivo evaluation of phenylpropanolamine release from microparticles and pellets. 2004 Aug 6 Zhu READ MORE
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Collapse temperature of bacterial suspensions: the effect of cell type and conce...
Votes:15 Comments:0
Collapse temperature of bacterial suspensions: the effect of cell type and concentration. 2004 Nov-Dec Fonseca F, Passot S, Lieben P, Marin M. Cryo Letters. 2004 Nov-Dec;25(6):425-34. PubMed UMR READ MORE
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Evidence that rehydrated, lyophilized red blood cells are sufficiently deformabl...
Votes:10 Comments:0
Evidence that rehydrated, lyophilized red blood cells are sufficiently deformable for normal microcirculation transit Published Online: 29 Nov 2004 Received: 2 June 2004; Accepted: 27 July 2004 Tho READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109801293/ABSTRACT

Reference System for Characterization of Bordetella pertussis Pulsed-Field Gel E...
Votes:4 Comments:0
Reference System for Characterization of Bordetella pertussis Pulsed-Field Gel Electrophoresis Profiles July 2004 Received 13 February 2004/ Returned for modification 20 March 2004/ Accepted 31 Mar READ MORE
http://jcm.asm.org/cgi/content/full/42/7/2890...

Impact of Methoxymycolic Acid Production by Mycobacterium bovis BCG Vaccines
Votes:37 Comments:0
Impact of Methoxymycolic Acid Production by Mycobacterium bovis BCG Vaccines May 2004 Received 9 September 2003/ Returned for modification 4 December 2003/ Accepted 31 January 2004 Adam Belley,1 D READ MORE
http://iai.asm.org/cgi/content/full/72/5/2803...

Physical characterization and macrophage cell uptake of mannan-coated nanopartic...
Votes:12 Comments:0
Physical characterization and macrophage cell uptake of mannan-coated nanoparticles. 2003 Jul Cui Z, Hsu CH, Mumper RJ. Drug Dev Ind Pharm. 2003 Jul;29(6):689-700 PubMed Division of Pharmaceutica READ MORE
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The application and mechanisms of polyethylene glycol 8000 on stabilizing lactat...
Votes:7 Comments:0
The application and mechanisms of polyethylene glycol 8000 on stabilizing lactate dehydrogenase during lyophilization. 2004 Jul-Aug Mi Y, Wood G. PDA J Pharm Sci Technol. 2004 Jul-Aug;58(4):192-202 READ MORE
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Lyophilization of lepidopteran midguts: a preserving method for Bacillus thuring...
Votes:21 Comments:0
Lyophilization of lepidopteran midguts: a preserving method for Bacillus thuringiensis toxin binding studies March 2004 Received 1 March 2004; accepted 8 March 2004. Available online 2 April 2004 READ MORE
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Lyophilization Made Easy
Votes:10 Comments:0
Lyophilization Made Easy March 2003 By Thomas A. Jennings, Ph.D. INSIGHT Vol. 6 No. 3 It was during a planning session for the forthcoming Lyophilization Conference 2003 that will be held in C READ MORE
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Parenteral Outsourcing
Votes:23 Comments:0
Parenteral Outsourcing March05 Gil Y. Roth Contract Pharma Oral delivery is still the Holy Grail for drug products, but plenty of new drugs (and many more in development) require injection. With s READ MORE
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Parenteral Sector Watch - Will the Bio-Shield keep demand high?
Votes:26 Comments:0
Parenteral Sector Watch Will the Bio-Shield keep demand high? NovDec03 By Gil Y. Roth Contract Pharma Depending on one?s metrics, the annual market for parenteral dose manufacturing services is a READ MORE
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Product & Process Considerations In the Development of Lyophilized
Votes:21 Comments:0
Product & Process Considerations In the Development of Lyophilized A review of how to identify the critical product and process variables that need to be optimized to formulate a successful lyophili READ MORE
http://pharmabioingredients.com/dec_04_f_2.htm

Freeze Drying 101
Votes:16 Comments:0
Freeze Drying 101 Some helpful freeze drying basics by Larry Ulfik VirTis After you finish our Lyophilization 101 notes, you may want to attend our Fundamentals of Lyophilization Seminar. Full det READ MORE
http://www.virtis.com/literature/freeze101.jsp

Freeze-Dryers ? Particle Monitoring Requirements, 2003
Votes:29 Comments:0
Freeze-Dryers ? Particle Monitoring Requirements, 2003 19-Dec-03 Mark Hallworth Pharmaceutical Business Manager Particle Measuring Systems Introduction Freeze-drying is used to produce the major READ MORE
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Preparation and In Vivo Toxicity Study of Solid Lipid Microparticles as Carrier ...
Votes:5 Comments:0
Preparation and In Vivo Toxicity Study of Solid Lipid Microparticles as Carrier for Pulmonary Administration Submitted: November 11, 2003; Accepted: March 10, 2004 Vanna Sanna,1 Nathalie Kirschvink READ MORE
http://www.aapspharmscitech.org/view.asp...

Influence of Lipid Nanocapsules Composition on Their Aptness to Freeze-Drying
Votes:37 Comments:0
Influence of Lipid Nanocapsules Composition on Their Aptness to Freeze-Drying 2005 By Claire Dulieu and Didier Bazile, MAINELAB-ETHYPHARM, F-49100 Angers, France Pharmaceutical Research You can vi READ MORE
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Poly(Lactide-Co-Glycolide) Microsphere Formulations of Darbepoetin Alfa: Spray D...
Votes:32 Comments:0
Poly(Lactide-Co-Glycolide) Microsphere Formulations of Darbepoetin Alfa: Spray Drying Is an Alternative to Encapsulation by Spray-Freeze Drying 2004 Paul A. Burke 1, Lisa A. Klumb 1, John D. Herberg READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Design of Freeze-Drying Processes for Pharmaceuticals: Practical Advice
Votes:27 Comments:0
Design of Freeze-Drying Processes for Pharmaceuticals: Practical Advice 2004 Xiaolin (Charlie) Tang and Michael J. Pikal, School of Pharmacy, University of Connecticut, Storrs, Connecticut, 06269-2 READ MORE
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Prediction of Glass Transition Temperature of Freeze-Dried Formulations by Molec...
Votes:40 Comments:0
Prediction of Glass Transition Temperature of Freeze-Dried Formulations by Molecular Dynamics Simulation 2003 Sumie Yoshioka, Yukio Aso and Shigeo Kojima, National Institute of Health Sciences, 1-18 READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Enhanced Aqueous Dissolution of a Poorly Water Soluble Drug by Novel Particle En...
Votes:16 Comments:0
Enhanced Aqueous Dissolution of a Poorly Water Soluble Drug by Novel Particle Engineering Technology: Spray-Freezing into Liquid with Atmospheric Freeze-Drying 2003 True L. Rogers1, 2, Andrew C. Nel READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The Effect of Additives on the Crystallization of Cefazolin Sodium During Freeze...
Votes:30 Comments:0
The Effect of Additives on the Crystallization of Cefazolin Sodium During Freeze-Drying Abira Pyne1, 2 and Raj Suryanarayanan1 (1) College of Pharmacy, University of Minnesota, 308 Harvard Street S. READ MORE
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The Case for Investment in R&D for Three Immunization Technologies: Recommendati...
Votes:27 Comments:0
12th GAVI Board Meeting? 9-10 December 2003, Geneva, Switzerland The Case for Investment in R&D for Three Immunization Technologies: Recommendations for GAVI Action This report was prepared by the READ MORE
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Impact of Formulations for Optimizing Lyophilization Process Development
Votes:30 Comments:0
Impact of Formulations for Optimizing Lyophilization Process Development March/April 2005 Feroz Jameel, Ph.D. and Sugunakar Y. Patro, Ph.D. Amgen, Inc. APR Abstract In this brief review, we dis READ MORE
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The Current State of PAT in Freeze-Drying
Votes:24 Comments:0
The Current State of PAT in Freeze-Drying January/February 2005 1Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwing-Maximilians-University, Munich 2Boehringer Ingelheim READ MORE
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Prediction of the Optimum Primary Drying Temperature from a Stepwise Temperature...
Votes:38 Comments:0
Prediction of the Optimum Primary Drying Temperature from a Stepwise Temperature Increased Lyophilization Cycle November/December 2004 Wei Liu, Ph.D., Amol S. Ketkar, Ph.D., and Ping Y. Yeh, Ph.D., READ MORE
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Lyophilizer Qualification: Some Practical Advice
Votes:14 Comments:0
Lyophilizer Qualification: Some Practical Advice September/October 2004 Thorsten Fischer, ZLB Behring GmbH (formerly Aventis Behring GmbH), Department Facility Qualification APR Key words: Contro READ MORE
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Radiosensitivity Study of Freeze-dried Antibodies to Gamma Irradiation
Votes:27 Comments:0
Radiosensitivity Study of Freeze-dried Antibodies to Gamma Irradiation July/August 2004 I. Caballero(1), S. Altan?s(3), A. Castillo(1), V. Deridder(2), T. Gomez(1), Y. Miralles(1), V. Naydenov(2), E READ MORE
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Development of Lyophilization Processes for Large Scale Production of Pharmaceut...
Votes:22 Comments:0
Development of Lyophilization Processes for Large Scale Production of Pharmaceutical Products July/August 2004 Ivette Novoa, Alida L?pez, Alex Guti?rrez, Orestes Mayo, Ph.D. (National Center of Biop READ MORE
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Steam Sterilization of the Stationary Large-Scale Freeze-Dryers (Lyophilizers)
Votes:36 Comments:0
Steam Sterilization of the Stationary Large-Scale Freeze-Dryers (Lyophilizers) May/June 2004 Ana Bacaoanu, Ph.D. Department of Chemical Engineering, Technical University of Iasi, Romania APR Abs READ MORE
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Use of a Range of Analytical Techniques in Support of the Freeze Drying of Biolo...
Votes:30 Comments:0
Use of a Range of Analytical Techniques in Support of the Freeze Drying of Biologicals May/June 2004 Paul Matejtschuk1, Julie Fleming1,2 & Roland Fleck2 Standards1 and Cell Biology & Imaging2 Divis READ MORE
Use of a Range of Analytical Techniques in Support of the Freeze Dryin...

Observation and Implications of Sonic Water Vapor Flow During Freeze-Drying
Votes:25 Comments:0
Observation and Implications of Sonic Water Vapor Flow During Freeze-Drying March/April 2004 Jim Searles, Ph.D. Eli Lilly and Company Global Parenteral Products Commercialization Technology Center READ MORE
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Leachables Found in Parenteral Drug Products
Votes:19 Comments:0
Leachables Found in Parenteral Drug Products March/April 2004 Jim Castner, Ph.D., Neal Williams, M.S. and Michael Bresnick, M.A. Bristol Myers Squibb Medical Imaging APR Introduction In the pr READ MORE
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The Importance of Radiochemical Analysis of Biological Fluids Before and After L...
Votes:33 Comments:0
The Importance of Radiochemical Analysis of Biological Fluids Before and After Lyophilization From Animals Dosed with [3H]-labeled Compounds in Drug Discovery January/February 2004 Hong Kim, Dan Pr READ MORE
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Lyophilization Optimization Using DSC and MT-DSC
Votes:9 Comments:0
Lyophilization Optimization Using DSC and MT-DSC January/February 2004 A. Rameau, A. Chevalier, and C. Neves Applied Physics, Pharmaceutical Sciences, Paris Research Center Aventis Pharma APR I READ MORE
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Practical Aspects of Freeze-Drying of Pharmaceutical and Biological Products Usi...
Votes:3 Comments:0
Practical Aspects of Freeze-Drying of Pharmaceutical and Biological Products Using Non-Aqueous Co-Solvent Systems Winter 2003 Dirk L. Teagarden, Ph.D. Pfizer Global Pharmaceutical Sciences, Depart READ MORE
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The Exploration and Use of Thermal Analytical Technologies During Formulation an...
Votes:17 Comments:0
The Exploration and Use of Thermal Analytical Technologies During Formulation and Process Development of Freeze-Dried Products Winter 2003 Nathaniel Milton, Ph.D., Abira Pyne, Ph.D., Dinesh Mishra, READ MORE
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Residual Moisture in Freeze-Dried Vaccines and Biological Products: Specificatio...
Votes:11 Comments:0
Residual Moisture in Freeze-Dried Vaccines and Biological Products: Specification and Measurement Fall 2003 Joan C. May, Ph.D. Center for Biologics Evaluation and Research, FDA APR Keywords: Ka READ MORE
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Enron - A Lesson for Lyophilization
Votes:6 Comments:0
Enron - A Lesson for Lyophilization Fall 2003 Thomas A. Jennings, Ph.D. Phase Technologies, Inc. APR On September 11, 2001 the United States experienced a disaster unparalleled in our history. T READ MORE
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Some Leading Edge Prospects in Lyophilization
Votes:20 Comments:0
Some Leading Edge Prospects in Lyophilization Summer 2003 Professor Louis Rey, Ph.D., Chemin de Verdonnet 2, CH 1010 Lausanne, Switzerland APR Introduction The development of Lyophilization/Free READ MORE
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Freeze-drying for IVDs
Votes:9 Comments:0
Freeze-drying for IVDs Originally Published IVD Technology June 2004 medical devicelink Advances in automation have imparted greater control over the lyophilization process. For reagents that are READ MORE
http://www.devicelink.com/ivdt/archive/04/06/009.html

Pre-Lyophilized Inspection Machine improves product quality
Votes:6 Comments:0
Pre-Lyophilized Inspection Machine improves product quality 3/1/2005 Pharmaceutical Processing The PLIM performs particle inspection prior to the lyophilization process. It's a camera-based system READ MORE
http://www.highbeam.com/library/doc0.asp...

Coolers provide continuous cooling as low as -45 C
Votes:20 Comments:0
Coolers provide continuous cooling as low as -45 C 3/1/2005 Laboratory Equipment The KR Series Coolers offers four low-temperature units that can be used to achieve low temperature capability with READ MORE
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FreeZone Stoppering Tray Dryer
Votes:34 Comments:0
FreeZone Stoppering Tray Dryer 3/1/2005 R & D The Labconco FreeZone Stoppering Tray Dryer for use with Labconco FreeZone 6-, 12-, and 18-L Freeze Dry Systems, has three shelves for batch or bulk READ MORE
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Binding of estrogenic compounds to recombinant estrogen receptor-[alpha]: applic...
Votes:9 Comments:0
Binding of estrogenic compounds to recombinant estrogen receptor-[alpha]: application to environmental analysis Balaguer, Patrick 3/1/2005 Environmental Health Perspectives Estrogenic activity in READ MORE
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PRESERVED, NON-INFECTIOUS CONTROL CELLS PREPARED BY THE MODULATION OR MODIFICATI...
Votes:7 Comments:0
12) Patent Application: (11) CA 2164131 ABSTRACT: The invention describes the preparation of preserved, non-infectious control cells. The control cells are prepared by modification, activation READ MORE
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Lyophilization of Vaccines: Current Trends
Votes:29 Comments:0
Lyophilization of Vaccines: Current Trends Gerald D. J. Adams August 2003 Humana Press Abstract: Regardless of how effective a vaccine may be in the laboratory, unless the suspension can be sta READ MORE
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Development of parenteral formulation for a novel angiogenesis inhibitor, CKD-73...
Votes:23 Comments:0
Development of parenteral formulation for a novel angiogenesis inhibitor, CKD-732 through complexation with hydroxypropyl--cyclodextrin 19 March 2004 Received 12 June 2002; Revised 25 November 2003 READ MORE
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In vitro testing of fresh and lyophilized reconstituted human and baboon platele...
Votes:13 Comments:0
In vitro testing of fresh and lyophilized reconstituted human and baboon platelets October 2004 C.R. Valeri1, H. Macgregor1, M.R. Barnard1, L. Summaria1, A.D. Michelson1, and G. Ragno1 Transfusion READ MORE
http://www.blackwell-synergy.com/openurl...

Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled auto...
Votes:7 Comments:0
Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets. February 1, 2005 CR Valeri, H MacGregor, MR Barnard, L Summaria, READ MORE
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Biomechanical strength of deep-frozen versus lyophilized large cortical allograf...
Votes:40 Comments:0
Biomechanical strength of deep-frozen versus lyophilized large cortical allografts June 2004 Received 18 July 2003; accepted 20 January 2004. Available online 9 April 2004. A. Nather, , A. Thamb READ MORE
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Analysis on ultrastructure of lyophilized red blood cells
Votes:16 Comments:0
Analysis on ultrastructure of lyophilized red blood cells April 1, 2003 Zhongguo Shi Yan Xue Ye Xue Za Zhi Medline Abstract HighWire Press Institute of Transfusion Medicine, Academy of Military READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;12744745...

Development and validation of an HPLC method for AG331 bulk drug substance and l...
Votes:10 Comments:0
Development and validation of an HPLC method for AG331 bulk drug substance and lyophilized powder for injection 29 June 2004 Received 25 October 2002; accepted 7 January 2004. Available online 19 READ MORE
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Development and characterization of a novel Cremophor? EL free liposome-based pa...
Votes:24 Comments:0
Development and characterization of a novel Cremophor? EL free liposome-based paclitaxel (LEP-ETU) formulation January 2005 Received 29 March 2004; accepted 7 June 2004. Available online 1 Septem READ MORE
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Enhancement of dissolution and oral bioavailability of gliquidone with hydroxy p...
Votes:18 Comments:0
Enhancement of dissolution and oral bioavailability of gliquidone with hydroxy propyl-beta-cyclodextrin. November 1, 2003 S Sridevi, AS Chauhan, KB Chalasani, AK Jain, and PV Diwan Pharmazie Medli READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;14664337...

Comparison of assays for determination of peptide content for lyophilized thymal...
Votes:32 Comments:0
Comparison of assays for determination of peptide content for lyophilized thymalfasin*. April 1, 2005 S Vemuri J Pept Res Medline Abstract HighWire Press SciClone Pharmaceuticals, Inc., 901 Mar READ MORE
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Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhan...
Votes:27 Comments:0
Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect February 2005 Yajun Chen1; Jie Liu1; Xiangliang Yang1; Xiaoling Zhao2; Huibi Xu2 Journa READ MORE
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Preparation, characterization, and stability of liposome-based formulations of m...
Votes:3 Comments:0
Preparation, characterization, and stability of liposome-based formulations of mitoxantrone. January 1, 2005 S Ugwu, A Zhang, M Parmar, B Miller, T Sardone, V Peikov, and I Ahmad Drug Dev Ind Pharm READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15773289...

Drug release from carbomer:carbomer sodium salt matrices with potential use as m...
Votes:16 Comments:0
Drug release from carbomer:carbomer sodium salt matrices with potential use as mucoadhesive drug delivery system. May 19, 2004 JM Llabot, RH Manzo, and DA Allemandi Int J Pharm Medline Abstract H READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15113614...

Production of Ophthalmic Lyophilisate Carriers by Fast Precision Freeze Drying (...
Votes:11 Comments:0
Production of Ophthalmic Lyophilisate Carriers by Fast Precision Freeze Drying (FPFD) 2004 R.J. Suverkrup1, O.A. Krasichkova1, M. Diestelhorst2 and S. Maier3 Invest Ophthalmol Vis Sci 2004;45: E- READ MORE
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Physicochemical investigation of the effects of water-soluble polymers on vinpoc...
Votes:5 Comments:0
Physicochemical investigation of the effects of water-soluble polymers on vinpocetine complexation with beta-cyclodextrin and its sulfobutyl ether derivative in solution and solid state. November 1, READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;14592691...

Preparation and pharmacokinetics of pirarubicin loaded dehydration?rehydration v...
Votes:19 Comments:0
Preparation and pharmacokinetics of pirarubicin loaded dehydration?rehydration vesicles 18 February 2003 Kumi Kawanoa, Kozo Takayamab, Tsuneji Nagaic and Yoshie Maitani International Journal of Ph READ MORE
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Formulation kit for liposomal doxorubicin composed of lyophilized liposomes.
Votes:32 Comments:0
Formulation kit for liposomal doxorubicin composed of lyophilized liposomes. January 1, 2003 PJ Stevens and RJ Lee Anticancer Res Medline Abstract HighWire Press Division of Pharmaceutics, Colle READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;12680245...

BCG vaccination at three different age groups: response and effectiveness.
Votes:27 Comments:0
BCG vaccination at three different age groups: response and effectiveness. April 1, 2005 George Briassoulis, Irene Karabatsou, Vasilis Gogoglou, and Athina Tsorva J Immune Based Ther Vaccines Medl READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;15804351...

Cake Shrinkage During Freeze Drying: A Combined Experimental and Theoretical Stu...
Votes:30 Comments:0
Cake Shrinkage During Freeze Drying: A Combined Experimental and Theoretical Study February 2005 S Rambhatla, J P Obert, S Luthra C Bhugra Michael J Pikal Pharmaceutical Development and Technolo READ MORE
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Controlled release of vancomycin from freeze-dried chitosan salts coated with di...
Votes:24 Comments:0
Controlled release of vancomycin from freeze-dried chitosan salts coated with different fatty acids by spray-drying July 1, 2003 T. Cerchiara, B. Luppi, F. Bigucci, M. Petrachi I. Orienti , V. Zecc READ MORE
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Freeze-Drying of Mannitol?Trehalose?Sodium Chloride-Based Formulations: The Impa...
Votes:19 Comments:0
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Gastroretentive Delivery Systems: Hollow Beads
Votes:33 Comments:0
Gastroretentive Delivery Systems: Hollow Beads 2004 R. Talukder and R. Fassihi Drug Development and Industrial Pharmacy Volume 30, Number 4 / 2004 You can view the abstract online. A subscripti READ MORE
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Gastric and Duodenal Antiulcer Effects of Rhizophora mangle
Votes:8 Comments:0
Gastric and Duodenal Antiulcer Effects of Rhizophora mangle May 2004 Luz Mar?a S?nchez Perera , Niurka Yasmin Batista, A. Rodr?guez, F. Farrada, C. Bulnes Pharmaceutical Biology (Formerly Internat READ MORE
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Enhanced Dispersibility and Deposition of Spray-dried Powders for Pulmonary Gene...
Votes:3 Comments:0
Enhanced Dispersibility and Deposition of Spray-dried Powders for Pulmonary Gene Therapy August 2003 Hao-Ying Li , Helen Neill, Rebecca Innocent, Peter Seville, Ian Williamson, James C. Birchall J READ MORE
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Scale-Up and Optimization of an Evaporative Drying Process Applied to Aqueous Di...
Votes:36 Comments:0
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Physical Stability of Micronized Powders Produced by Spray-Freezing into Liquid ...
Votes:30 Comments:0
Physical Stability of Micronized Powders Produced by Spray-Freezing into Liquid (SFL) to Enhance the Dissolution of an Insoluble Drug 2003 True L. Rogers, Keith P. Johnston, Robert O. Williams III READ MORE
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The results of a proficiency panel of lyophilized urine samples showed high spec...
Votes:25 Comments:0
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Quil A?lipid powder formulations releasing ISCOMs and related colloidal stucture...
Votes:19 Comments:0
Quil A?lipid powder formulations releasing ISCOMs and related colloidal stuctures upon hydration 2 March 2005 Patrick H. Demana, Nigel M. Davies, Sarah Hook and Thomas Rades Journal of Controlled READ MORE
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Synthesis and characterization of Gd2O3:Eu3+ phosphor nanoparticles by a sol-lyo...
Votes:33 Comments:0
Synthesis and characterization of Gd2O3:Eu3+ phosphor nanoparticles by a sol-lyophilization technique July 2003 C. Louis, R. Bazzi, Marco A. Flores, W. Zhenga, K. Lebbou, O. Tillementa, B. Mercie READ MORE
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Biopreservation of Red Blood Cells: Past, Present, and Future
Votes:9 Comments:0
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Quality control material for free thyroxine immunoanalysis: rather frozen than l...
Votes:22 Comments:0
Quality control material for free thyroxine immunoanalysis: rather frozen than lyophilized? April 2005 A. Agin, , J. Mittler, M. Offner and R. Sapin Immuno-analyse & Biologie Sp?cialis?e Science READ MORE
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A comparison of vials with ampoules for the storage of biological reference mate...
Votes:17 Comments:0
A comparison of vials with ampoules for the storage of biological reference materials 13 March 2005 Paul Matejtschuk, Shakeel Rafiq, Suzanne Johnes and Rose Gaines Das Science Direct Lyophilizati READ MORE
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Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphen...
Votes:12 Comments:0
Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy January 2003 Yvette Niamien Konan, Radovan Cerny, Joselyne READ MORE
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Biocompatible superparamagnetic iron oxide nanoparticles used for contrast agent...
Votes:25 Comments:0
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Coating alginate microspheres with a serum albumin-alginate membrane: applicatio...
Votes:20 Comments:0
Coating alginate microspheres with a serum albumin-alginate membrane: application to the encapsulation of a peptide February 2005 Reynald Hurteaux, Florence Edwards-L?vy, Dominique Laurent-Maquin a READ MORE
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Comparison by LC-MS and MALDI-MS of prostate-specific antigen from five commerci...
Votes:34 Comments:0
Comparison by LC-MS and MALDI-MS of prostate-specific antigen from five commercial sources with certified reference material 613 February 2005 Mary B. Satterfield and Michael J. Welch Clinical Bio READ MORE
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The effect of pore size on cell adhesion in collagen-GAG scaffolds
Votes:9 Comments:0
The effect of pore size on cell adhesion in collagen-GAG scaffolds February 2005 F. J. O?Briena,, B. A. Harley, I. V. Yannas and L. J. Gibson Biomaterials Science Direct Abstract The biologica READ MORE
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In situ observation of hydroxyapatite nanocrystal formation from amorphous calci...
Votes:23 Comments:0
In situ observation of hydroxyapatite nanocrystal formation from amorphous calcium phosphate in calcium-rich solutions 15 June 2005 Sujin Kim, Hyun-Seung Ryu, Hyunho Shin, Hyun Suk Jung and Kug Sun READ MORE
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Study of gelatin-containing artificial skin V: fabrication of gelatin scaffolds ...
Votes:36 Comments:0
Study of gelatin-containing artificial skin V: fabrication of gelatin scaffolds using a salt-leaching method May 2005 Sang Bong Lee, Yong Han Kim, Moo Sang Chong, Seung Hwa Hong and Young Moo Lee READ MORE
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Determination by NMR of the binding constant for the molecular complex between a...
Votes:12 Comments:0
Determination by NMR of the binding constant for the molecular complex between alprostadil and a-cyclodextrin: Implications for a freeze-dried formulation April 12, 2005 Tore Ramstad , Chad E. Hadd READ MORE
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Optimization of a Bifidobacterium longum production process
Votes:26 Comments:0
Optimization of a Bifidobacterium longum production process 21 February 2005 Kristiina Kiviharju, Matti Leisola and Tero Eerik?inen Journal of Biotechnology Science Direct Abstract Bifidobac READ MORE
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Preparation, properties and biological application of pH-sensitive poly(ethylene...
Votes:20 Comments:0
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Pharmacokinetic profiles of two tablet formulations of piroxicam
Votes:34 Comments:0
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In vivo anti-tumor effect of dual release of cisplatin and adriamycin from biode...
Votes:9 Comments:0
In vivo anti-tumor effect of dual release of cisplatin and adriamycin from biodegradable gelatin hydrogel March 2005 Mitsunaga Konishia, Yasuhiko Tabata, Masatoshi Kariya, Hossein Hosseinkhani, Aya READ MORE
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Effect of cryoprotectants on the stability and aerosol performance of nebulized ...
Votes:23 Comments:0
Effect of cryoprotectants on the stability and aerosol performance of nebulized aviscumine, a 57-kDa protein July 2003 Hartwig Steckel, Fadi Eskandara and Klaus Witthohn European Journal of Pharm READ MORE
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Study of freeze-dried quercetin?cyclodextrin binary systems by DSC, FT-IR, X-ray...
Votes:37 Comments:0
Study of freeze-dried quercetin?cyclodextrin binary systems by DSC, FT-IR, X-ray diffraction and SEM analysis February 2004 Tayade Pralhad and Kale Rajendrakumar Journal of Pharmaceutical and Bio READ MORE
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Effects of liquid and freeze-dried grapefruit juice on the pharmacokinetics of p...
Votes:31 Comments:0
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Development of a LC method for pharmaceutical quality control of the antimetasta...
Votes:7 Comments:0
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Water sorption?desorption behaviour of methyl methacrylate?starch copolymers: ef...
Votes:39 Comments:0
Water sorption?desorption behaviour of methyl methacrylate?starch copolymers: effect of hydrophobic graft and drying method April 2005 I. Bravo-Osuna, C. Ferrero and M.R. Jim?nez-Castellanos Eur READ MORE
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Improvement of gliquidone hypoglycaemic effect in rats by cyclodextrin formulati...
Votes:29 Comments:0
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Comparison of scanning electron microscopy, dynamic light scattering and analyti...
Votes:4 Comments:0
Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly(butyl cyanoacrylate) nanoparticles March 2004 Alexander Bootz, Vitali V READ MORE
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Protocols for stability and homogeneity studies of drugs for its application to ...
Votes:37 Comments:0
Protocols for stability and homogeneity studies of drugs for its application to doping control July 2004 C. Jim?nez, R. Ventura, J. Segura and R. de la Torre Analytica Chimica Acta, Volume 515, Is READ MORE
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Drug release kinetics and fronts movement studies from methyl methacrylate (MMA)...
Votes:32 Comments:0
Drug release kinetics and fronts movement studies from methyl methacrylate (MMA) copolymer matrix tablets: effect of copolymer type and matrix porosity September 2003 C. Ferrero, I. Bravo and M. R. READ MORE
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Interpolymer complexes of poly(acrylic acid) and chitosan: influence of the ioni...
Votes:7 Comments:0
Interpolymer complexes of poly(acrylic acid) and chitosan: influence of the ionic hydrogel-forming medium April 2003 Paloma M. de la Torre, Susana Torrado and Santiago Torrado Biomaterials, Volume READ MORE
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Preparation and evaluation of a liposomal formulation of sodium cromoglicate
Votes:21 Comments:0
Preparation and evaluation of a liposomal formulation of sodium cromoglicate January 2003 M. S. Nagarsenker and V. Y. Londhe International Journal of Pharmaceutics, Volume 251, Issues 1-2, 30 Janua READ MORE
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Influence of small B-cyclodextrin complexation on carbamazepine release from hyd...
Votes:15 Comments:0
Influence of B-cyclodextrin complexation on carbamazepine release from hydroxypropyl methylcellulose matrix tablets January 2003 Let?cia S. Koester, Clarissa R. Xavier, Paulo Mayorga and Valquiria L READ MORE
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Critical effect of freezing/freeze-drying on sustained release of FITC-dextran e...
Votes:10 Comments:0
Critical effect of freezing/freeze-drying on sustained release of FITC-dextran encapsulated within PLGA microspheres March 2004 Tae Hyoung Kim and Tae Gwan Park International Journal of Pharmaceuti READ MORE
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Anomalous dissolution behaviour of tablets prepared from sugar glass-based solid...
Votes:24 Comments:0
Anomalous dissolution behaviour of tablets prepared from sugar glass-based solid dispersions July 2004 D. J. van Drooge, W. L. J. Hinrichs and H. W. Frijlink Journal of Controlled Release, Volume 9 READ MORE
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Is Lyophilization Deceptive and Devious at Times?
Votes:27 Comments:0
Is Lyophilization Deceptive and Devious at Times? Thomas A. Jennings, Ph.D. December 2003 INSIGHT Recently I was in correspondence with a colleague whom I respect a great deal. I share with them m READ MORE
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Preparation of celecoxib-dimethyl-?-cyclodextrin inclusion complex: characteriza...
Votes:40 Comments:0
Preparation of celecoxib-dimethyl-?-cyclodextrin inclusion complex: characterization and in vitro permeation study Received 6 December 2004; revised 1 March 2005; accepted 1 March 2005. Available READ MORE
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Lab-scale freeze-drier from Buchi
Votes:19 Comments:0
Lab-scale freeze-drier from Buchi 09/03/2004 DrugResearcher.com Switzerland?s Buchi has launched a small-scale oven for freeze-drying samples that puts the technology within reach of laboratories READ MORE
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MSU research questions method used to remove virus from bones and tissue used fo...
Votes:32 Comments:0
MSU research questions method used to remove virus from bones and tissue used for transplants 3/31/2004 Contact: Steven P. Arnoczky, Small Animal Clinical Sciences, (517) 353-8964, arnoczky@cvm.msu. READ MORE
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Eliminating the freeze-dry bottleneck
Votes:27 Comments:0
Eliminating the freeze-dry bottleneck 9 April 2003 Laboratory Talk CryoDry is an extension of Ilmvac's existing laboratory and production freeze drying business, which encompasses drying in flasks, READ MORE
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Development of simple thiol-reactive liposome formulations, one-step analysis an...
Votes:30 Comments:0
Development of simple thiol-reactive liposome formulations, one-step analysis and physicochemical characterization Kaourma E, Hatziantoniou S, Georgopoulos A, Kolocouris A, Demetzos C. 2005 Apr J READ MORE
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Enhancement of enzyme activity and enantioselectivity by cyclopentyl methyl ethe...
Votes:25 Comments:0
Enhancement of enzyme activity and enantioselectivity by cyclopentyl methyl ether in the transesterification catalyzed by Pseudomonas cepacia lipase co-lyophilized with cyclodextrins Mine Y, Zhang L, READ MORE
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Discussion of Lyophilization or Freeze Drying in Trays
Votes:19 Comments:0
Discussion of Lyophilization or Freeze Drying in Trays Thomas A. Jennings, Ph.D and Professor Ana Bacaoanu, Ph.D?. May 2003 INSIGHT No doubt that trays played a major role in the early days of lyo READ MORE
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Role of Statistics in Lyophilization or Freeze Drying
Votes:14 Comments:0
Role of Statistics in Lyophilization or Freeze Drying Thomas A. Jennings, Ph.D. January 2003 INSIGHT There is little doubt, at least in my mind, that lyophilization or freeze drying (see INSIGHT V READ MORE
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Laboratoire Valmont has applied
Votes:9 Comments:0
Laboratoire Valmont has applied 1/1/2003 Household & Personal Products Industry Laboratoire Valmont has applied its state-of-the-art technology, lyophilization, to its HP DNA active for the compan READ MORE
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New particle engineering technology improves drug solubility
Votes:3 Comments:0
New particle engineering technology improves drug solubility Haystead, John 1/1/2003 Pharmaceutical Technology According to industry studies, more than 30% of new chemical entities developed durin READ MORE
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Contract services' crystal ball: developments in 2002 such as acquisitions, exce...
Votes:17 Comments:0
Contract services' crystal ball: developments in 2002 such as acquisitions, excess manufacturing capacity, and less funding for biotechnology will continue to affect the industry long into the new yea READ MORE
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DSM pharmaceuticals to double sterile manufacturing capacity
Votes:30 Comments:0
DSM pharmaceuticals to double sterile manufacturing capacity Russell, Ronelle 2/1/2003 Pharmaceutical Technology In response to steadily increasing demand, DSM Pharmaceuticals (Greenville, NC) is READ MORE
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Future imperfect for Quintiles?
Votes:25 Comments:0
Future imperfect for Quintiles? Miller, Jim 3/1/2003 Pharmaceutical Technology Europe Following the rejection of Dennis Gillings' offer to buy back Quintiles, the company is looking at alternativ READ MORE
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A review and classification of emerging excipients in parenteral medications
Votes:39 Comments:0
A review and classification of emerging excipients in parenteral medications Ugwu, Sydney O. 3/1/2003 Pharmaceutical Technology As parenteral drug delivery becomes more complex and sophisticated, READ MORE
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Virus inactivation in the 1990s--and into the 21st century Part 6, inactivation ...
Votes:14 Comments:0
Virus inactivation in the 1990s--and into the 21st century Part 6, inactivation methods grouped by virus Boose, Jeri Ann 4/1/2003 Biopharm International Smallest of the microorganisms, viruses de READ MORE
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Design criteria and containment evaluation for pharmaceutical containment system...
Votes:9 Comments:0
Design criteria and containment evaluation for pharmaceutical containment systems in aseptic dosage form manufacturing facilities Takeda, Morihiko 5/1/2003 Pharmaceutical Technology This article READ MORE
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When it comes to lyophilization, we take the cake
Votes:22 Comments:0
When it comes to lyophilization, we take the cake 10/1/2003 Pharmaceutical Technology What's the surest path to a bigger ROI? The unparalleled customer service you can get from Baxter Pharmaceutic READ MORE
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Freeze Dryers: space saving design
Votes:36 Comments:0
Freeze Dryers: space saving design 10/1/2003 Pharmaceutical Processing LYOVAC[R] freeze-drying systems feature a space-saving design that allows for flexible integration into a pharmaceutical proc READ MORE
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Freeze drying system: for research and process development
Votes:12 Comments:0
Freeze drying system: for research and process development 10/1/2003 Pharmaceutical Processing The LyoStar II features an enhanced cascade refrigeration system that has more horsepower to provide READ MORE
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Measurement of fractional whole-body gluconeogenesis in humans from blood sample...
Votes:6 Comments:0
Measurement of fractional whole-body gluconeogenesis in humans from blood samples using [sup.2]H nuclear magnetic resonance spectroscopy Roden, M. 10/1/2003 Diabetes Several problems limit quanti READ MORE
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Near-infrared spectroscopy as a process analytical tool
Votes:39 Comments:0
Near-infrared spectroscopy as a process analytical tool Bakeev, Katherine A. 9/1/2003 Pharmaceutical Technology Europe Near-infrared (NIR) spectroscopy has been used for qualitative and quantitat READ MORE
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Aseptic formulation and filling using isolator technology
Votes:34 Comments:0
Aseptic formulation and filling using isolator technology Akers, James 8/1/2003 Pharmaceutical Technology; Isolator technology can be used in clinical product formulation and filling facilities t READ MORE
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Sterile filling and capping system: increased flexibility and output
Votes:9 Comments:0
Sterile filling and capping system: increased flexibility and output 2/1/2004 Pharmaceutical Processing The FMB210 monobloc system is designed for filling vials, insertion of lyophilization or inj READ MORE
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A Review of mouth dissolving tablet technologies
Votes:4 Comments:0
A Review of mouth dissolving tablet technologies Gothoskar, A.V. 11/1/2003 Pharmaceutical Technology In addition to successfully delivering a drug to the body, the goal of any drug delivery syste READ MORE
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Optimization of an Alum-Adsorbed Vaccine Powder Formulation for Epidermal Powder...
Votes:39 Comments:0
Optimization of an Alum-Adsorbed Vaccine Powder Formulation for Epidermal Powder Immunization July 2003 Yuh-Fun Maa1 , Cassandra Shu1, Mahmoud Ameri1, Cindy Zuleger1, Jenny Che1, Jorge E. Osorio1, READ MORE
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Research Questions Transplant Safety Procedure
Votes:34 Comments:0
Research Questions Transplant Safety Procedure 2004-04-01 Source: Michigan State University ScienceDaily Lyophilization, a method once thought to inactivate retroviruses such as HIV from bones READ MORE
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Why do We Use RTD?s to Monitor the Freeze Drying Process?
Votes:4 Comments:0
Why do We Use RTD?s to Monitor the Freeze Drying Process? June 2003 Thomas A. Jennings, Ph.D. Insight The question posed by the title of this INSIGHT is one that I have often asked myself and pose READ MORE
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Problems with Thermocouple Measurements
Votes:37 Comments:0
Problems with Thermocouple Measurements July 2003 Insight There are at present two basic temperature transducers used in conjunction with the lyophilization or freeze drying process, i.e., RTD and READ MORE
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Old Freeze Dryer Repair or Replace?
Votes:12 Comments:0
Old Freeze Dryer Repair or Replace? November 2003 Thomas A. Jennings Insight This is a question that in time will certainly arise regarding every freeze dryer when it becomes more than 10 years o READ MORE
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Gamma Sterilization of Pharmaceuticals
Votes:34 Comments:0
Gamma Sterilization of Pharmaceuticals May 2004 By Ruth Garcia, Betty Howard, Rose LaRue, Glenn Parton, and John WalkerSteris Isomedix Services (Mentor, OH) Sterility is desirable not only for medi READ MORE
http://www.steris.com/isomedix/PDF/Pharma_pmpn_May_2004.pdf.

Deep Freeze
Votes:10 Comments:0
Deep Freeze August/September 2003 By Narlin B. Beaty, PhD PharmaQuality If Mr. Freeze had current lyophilization processes at his disposal, he might have triumphed over Batman. Fortunately, ph READ MORE
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Why Lyophilize?
Votes:23 Comments:0
Why Lyophilize? August/September 2003 By Walt Pebley PharmaQuality Lyophilization is traditionally used for preserving heat-sensitive parenterals. The elegance of lyophilization or ?low-temper READ MORE
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Just a spoonful of sugar
Votes:19 Comments:0
Just a spoonful of sugar April 2005 Chemistry World In short Thermostable vaccines can be made by spray drying a mixture of vaccine and sugars in hot air, resulting in vaccines encased in sugar-gl READ MORE
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Potato-based vaccine success comes too late
Votes:13 Comments:0
Potato-based vaccine success comes too late April 26, 2005 Andy Coghlan New Scientist Genetically engineered potatoes containing a hepatitis B vaccine have successfully boosted immunity in their READ MORE
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Thermostability of Vaccines
Votes:27 Comments:0
Thermostability of Vaccines 2003 Mrudula K. Lala Kamlesh R. Lala Indian Pediatrics Cold chain is the system of transporting, storing and distributing vaccine in a potent state at recommended tem READ MORE
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THE BIG FREEZE DRY
Votes:35 Comments:0
THE BIG FREEZE DRY February 2004 saf-T-News Take an organic substance. Now, remove the water (or other solvent). Remove enough to preserve the substance and in such a way that the cell structures a READ MORE
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Regents Professor creates vaccines for developing countries
Votes:30 Comments:0
Regents Professor creates vaccines for developing countries February 13, 2004 Skip Derra ASU News Releases Charlie Arntzen has been exploring the use of crops to produce vaccines for 13 years. W READ MORE
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Control of Japanese encephalitis in India: A reality
Votes:25 Comments:0
Control of Japanese encephalitis in India: A reality 2004 Kabilan Lalitha The Indian Journal of Pediatrics ? Abstract Japanese encephalitis is considered as a serious disease due to the compl READ MORE
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New Meds Melt in Your Mouth
Votes:35 Comments:0
New Meds Melt in Your Mouth August 6, 2003 By Dwayne Hunter Betterhumans Staff Billed as "melt-in-your-mouth" tablets, a new drug-delivery technology is being promoted as an easier, better, cost READ MORE
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Carrier-based Strategies for Targeting Protein and Peptide Drugs to the Lungs
Votes:18 Comments:0
Carrier-based Strategies for Targeting Protein and Peptide Drugs to the Lungs March 24, 2005 Sally-Ann Cryan The AAPS Journal 2005; 7 (1) Article 4 Please visit the web site to view the article in READ MORE
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Liposomal Amikacin Dry Powder Inhaler: Effect of Fines on In Vitro Performance
Votes:32 Comments:0
Liposomal Amikacin Dry Powder Inhaler: Effect of Fines on In Vitro Performance August 2004 Shrenik P. Shah and Ambikanandan Misra AAPS PharmSciTech 2004; 5 (4) Article 65 Please visit the web site READ MORE
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Etoposide-incorporated Tripalmitin Nanoparticles With Different Surface Charge: ...
Votes:8 Comments:0
Etoposide-incorporated Tripalmitin Nanoparticles With Different Surface Charge: Formulation, Characterization, Radiolabeling, and Biodistribution Studies October 2004 Lakkireddy Harivardhan Reddy, R READ MORE
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?-Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization, and...
Votes:21 Comments:0
?-Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization, and Dissolution Studies March 2004 M. Narender Reddy, Tasneem Rehana, S. Ramakrishna, K. P. R. Chowdary, and Prakash V. D READ MORE
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Understanding the physical stability of freeze dried dosage forms from the glass...
Votes:16 Comments:0
Understanding the physical stability of freeze dried dosage forms from the glass transition temperature of the amorphous components 2003 Shaun Fitzpatrick, Robert Saklatvala J. Pharm. Sci. Vol. 92 READ MORE
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Investigation of the stabilisation of freeze-dried lysozyme and the physical pro...
Votes:11 Comments:0
Investigation of the stabilisation of freeze-dried lysozyme and the physical properties of the formulations 2004 Liao, Y.-H., Brown, M.B., Martin, G.P. European Journal of Pharmaceutics and Biophar READ MORE
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Patent litigation ? from start to finish (including appeal) in nine months
Votes:5 Comments:0
Patent litigation ? from start to finish (including appeal) in nine months Article by Nick Beckett Free Weekly Newsletters 26 April 2005 Mondaq The Court of Appeal has rendered its decision in th READ MORE
http://www.mondaq.com/i_article.asp_Q_articleid_E_32195

Students Take Smarts To State Science Fair
Votes:19 Comments:0
Students Take Smarts To State Science Fair Jason DeRusha reports Apr 4, 2005 WCCO St. Paul (WCCO) Hundreds of Minnesota kids will be showing off their science smarts Monday at the Minnesota Acade READ MORE
http://wcco.com/localnews/local_story_094103517.html

Spectroscopic investigation of the aggregation state of amphotericin B during lo...
Votes:13 Comments:0
Spectroscopic investigation of the aggregation state of amphotericin B during loading, freeze-drying, and reconstitution of polymeric micelles Monica Adams, Glen S. Kwon Published 22 November 2004 READ MORE
http://www.ualberta.ca/~csps/JPPS7(4)SpecialIssue/G.Kwon/AmB.htm

How to freeze mamalian cells
Votes:27 Comments:0
How to freeze mamalian cells June 29, 2004 The Science Advisory Board Description This protocol describes how to freeze tissue culture cells (mamalian) in a way that they will be viable when thaw READ MORE
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Development of Liposomal Amphotericin B Dry Powder Inhaler Formulation
Votes:3 Comments:0
Development of Liposomal Amphotericin B Dry Powder Inhaler Formulation 2005 S. Shah1; Ambikanandan Misra1 Drug Delivery, 2004, vol. 11, no. 4, pp. 247-253(7) You can view the abstract online. A READ MORE
http://www.ingentaconnect.com/search/article...

Pegylated Poly(Lactide) and Poly(Lactide-Co-Glycolide) Nanoparticles: Preparatio...
Votes:35 Comments:0
Pegylated Poly(Lactide) and Poly(Lactide-Co-Glycolide) Nanoparticles: Preparation, Properties and Possible Applications in Drug Delivery October 2004 Konstantinos Avgoustakis Current Drug Delivery, READ MORE
http://www.ingentaconnect.com/search/article...

A Novel One-Step Drug-Loading Procedure for Water-Soluble Amphiphilic Nanocarrie...
Votes:30 Comments:0
A Novel One-Step Drug-Loading Procedure for Water-Soluble Amphiphilic Nanocarriers June 2004 Fournier E.; Dufresne M-H.; Smith D.C.; Ranger M.; Leroux J-C. Pharmaceutical Research, June 2004, vol. READ MORE
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Measurement of lyophilisation primary drying rates by freeze-drying microscopy
Votes:38 Comments:0
Measurement of lyophilisation primary drying rates by freeze-drying microscopy S. Zhai, R. Taylor, R. Sanches and N. K. H. Slater June 2003 Chemical Engineering Science Abstract The mass transfe READ MORE
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Measurement of lactose crystallinity using Raman spectroscopy
Votes:14 Comments:0
Measurement of lactose crystallinity using Raman spectroscopy Bridget M. Murphya, , Stuart W. Prescottb and Ian Larson 22 January 2005 Journal of Pharmaceutical and Biomedical Analysis Abstract READ MORE
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Preparation and evaluation of a chitosan salt?poloxamer 407 based matrix for buc...
Votes:8 Comments:0
Preparation and evaluation of a chitosan salt?poloxamer 407 based matrix for buccal drug delivery S. Cafaggi, , R. Leardi, B. Parodi, G. Caviglioli, E. Russo and G. Bignardi 20 January 2005 Journal READ MORE
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Large-scale production of lipoplexes with long shelf-life
Votes:3 Comments:0
Large-scale production of lipoplexes with long shelf-life Jule Clementa, 1, , , Karin Kiefera, 1, Andrea Kimpflera, Patrick Garidelb and Regine Peschka-S?ss January 2005 European Journal of Pharmac READ MORE
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Stabilisation by freeze-drying of cationically modified silica nanoparticles for...
Votes:36 Comments:0
Stabilisation by freeze-drying of cationically modified silica nanoparticles for gene delivery M. Sametia, G. Bohra, M. N. V. Ravi Kumara, C. Kneuera, 1, U. Bakowskya, M. Nackenb, H. Schmidtb and C. READ MORE
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Direct screening of lyophilised biological fluids for bile acids using an evapor...
Votes:30 Comments:0
Direct screening of lyophilised biological fluids for bile acids using an evaporative light scattering detector Andr?s Criado, Soledad C?rdenas, Mercedes Gallego and Miguel Valc?rcel 25 July 2003 J READ MORE
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A novel dry powder influenza vaccine and intranasal delivery technology: inducti...
Votes:25 Comments:0
A novel dry powder influenza vaccine and intranasal delivery technology: induction of systemic and mucosal immune responses in rats Juan Huanga, Robert J. Garmiseb, Timothy M. Crowderc, Kevin Mara, C READ MORE
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Solid dispersions based on inulin for the stabilisation and formulation of ?9-te...
Votes:39 Comments:0
Solid dispersions based on inulin for the stabilisation and formulation of ?9-tetrahydrocannabinol D. J. van Drooge , , W. L. J. Hinrichs , K. A. M. Wegman , M. R. Visser , A. C. Eissens and H. W. Fr READ MORE
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Zydus Cadila gears up for Brazil in April
Votes:14 Comments:0
Zydus Cadila gears up for Brazil in April FEBRUARY 24, 2005 TIMES NEWS NETWORK AHMEDABAD: Zydus Cadila is all set to enter the lucrative generics market in Brazil in April. The Rs 1,170 crore pharm READ MORE
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Cryopreservation: fundamentals, mechanisms of damage on freezing/thawing and app...
Votes:9 Comments:0
Cryopreservation: fundamentals, mechanisms of damage on freezing/thawing and application in culture collections Author: John G. Day 1 August 2004 E. Schweizerbart Science Publishers Abstract: A READ MORE
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In vitro testing of fresh and lyophilized reconstituted human and baboon platele...
Votes:22 Comments:0
In vitro testing of fresh and lyophilized reconstituted human and baboon platelets C.R. Valeri; H. Macgregor; M.R. Barnar; L. Summaria; A.D. Michelson; G. Ragno October 2004 Blackwell Publishing READ MORE
http://www.ingentaconnect.com/search/article...

Freeze-Drying Process Design by Manometric Temperature Measurement: Design of a ...
Votes:36 Comments:0
Freeze-Drying Process Design by Manometric Temperature Measurement: Design of a Smart Freeze-Dryer Tang, Xiaolin (Charlie) 1; Nail, Steven L. 2; Pikal, Michael J. April 2005 Publisher: Kluwer Acad READ MORE
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Overview of Aseptic Fill/Finish Manufacturing
Votes:28 Comments:0
Overview of Aseptic Fill/Finish Manufacturing Douglas Stockdale, President, Stockdale Associates, Inc. American Pharmaceutical Review Please visit the web site to view the article in its entirety. READ MORE
http://www-personal.engin.umich.edu/~lishen/Aseptic/American%20Pharmac...

A human papillomavirus type 16 vaccine by oral delivery of L1 protein
Votes:4 Comments:0
A human papillomavirus type 16 vaccine by oral delivery of L1 protein June 2005 Toshiyuki Sasagawa, Mayuko Tania, Walid Basha, Robert C. Rose, Hideki Tohda, Yuko Giga-Hama, Khadijeh K. Azar, Hidey READ MORE
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Stability of fat-soluble and water-soluble vitamins in artificially prepared, vi...
Votes:18 Comments:0
Stability of fat-soluble and water-soluble vitamins in artificially prepared, vitamin-enriched, lyophilized serum June 2004 Hiroshi Ihara 1, Naotaka Hashizume 1, Tadashi Matsubayashi 2, Koichi Futak READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109076051/ABSTRACT

Commercial manufacturing scale formulation and analytical characterization of th...
Votes:26 Comments:0
Commercial manufacturing scale formulation and analytical characterization of therapeutic recombinant antibodies July 2004 Reed J. Harris 1, Steven J. Shire 2, Charles Winter 3 1Analytical Chemistr READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109565439/ABSTRACT

Mislabeled H2N2 Virus Leads to Tighter Inventory Control Rules
Votes:14 Comments:0
Mislabeled H2N2 Virus Leads to Tighter Inventory Control Rules April 17, 2005 Recombinomics Commentary >> In response to the problem, the CDC announced this week that the agency would speed up pla READ MORE
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FDA Approvals: Retisert, WinRho SDF, IMx Sirolimus Assay
Votes:9 Comments:0
FDA Approvals: Retisert, WinRho SDF, IMx Sirolimus Assay April 28, 2005 Yael Waknine Medscape The U.S. Food and Drug Administration (FDA) has approved an orphan drug indication for fluocinolone ac READ MORE
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Venus Remedies to set up plant in HP
Votes:3 Comments:0
Venus Remedies to set up plant in HP 4/11/2005 India Infoline Ltd Venus Remedies Ltd on Monday said that it has acquired 5 acres of land for setting up an exclusive manufacturing facility at Baddi, READ MORE
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Evidence of Risk for H2N2 1957 Pandemic Flu
Votes:36 Comments:0
Evidence of Risk for H2N2 1957 Pandemic Flu April 18, 2005 Commentary Recombinomics >> Even if a sample included in a test kit is a strain of a deadly virus, the sample is not necessarily dangero READ MORE
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In a secretive UK lab, Vivienne Parry meets the scientists who protect the world...
Votes:15 Comments:0
In a secretive UK lab, Vivienne Parry meets the scientists who protect the world's health April 21, 2005 Vivienne Parry The Guardian Tucked away behind a service station in South Mimms, Hertfor READ MORE
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Incremental Addition of Parenteral Capacity Case Study for a Lyophilizer
Votes:28 Comments:0
Incremental Addition of Parenteral Capacity Case Study for a Lyophilizer Narlin B. Beaty, Ph.D. Chesapeake Biological Laboratories, Inc. Please visit the web site to view the article in its entiret READ MORE
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Low molecular weight dextrans stabilize nonviral vectors during lyophilization a...
Votes:36 Comments:0
Low molecular weight dextrans stabilize nonviral vectors during lyophilization at low osmolalities: concentrating suspensions by rehydration to reduced volumes 2005 Thomas J. Anchordoquy, Taylor K. READ MORE
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Issues Associated with Large-Scale Production of Liposomal Formulations
Votes:34 Comments:0
Issues Associated with Large-Scale Production of Liposomal Formulations By: Tony Nakhla, PhD; Mike Marek, MS, RPh; & Tom Kovalcik, PhD Drug Delivery Technology INTRODUCTION It was reported more th READ MORE
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Using a Portfolio of Particle Growth Technologies to Enable Delivery of Drugs Wi...
Votes:29 Comments:0
Using a Portfolio of Particle Growth Technologies to Enable Delivery of Drugs With Poor Water Solubility 2004 By: R.D. Connors and E.J. Elder, RPh, PhD Drug Delivery Technology INTRODUCTION The READ MORE
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The Ins and Outs of Prefilled Syringes
Votes:4 Comments:0
The Ins and Outs of Prefilled Syringes May 2003 by Jenevieve Blair Polin, Contributing Editor Pharmaceutical & Medical Packaging Pharmaceutical companies are realizing the benefits of prefilled sy READ MORE
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Lyophilized Paclitaxel Magnetoliposomes as a Potential Drug Delivery System for ...
Votes:37 Comments:0
Lyophilized Paclitaxel Magnetoliposomes as a Potential Drug Delivery System for Breast Carcinoma via Parenteral Administration: In Vitro and in Vivo Studies April 2005 J. Q. Zhang 1, Z. R. Zhang 2, READ MORE
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A lyophilized aqueous extract of Maytenus ilicifolia leaves inhibits histamine-m...
Votes:31 Comments:0
A lyophilized aqueous extract of Maytenus ilicifolia leaves inhibits histamine-mediated acid secretion in isolated frog gastric mucosa June 2004 Patr?cia Maria Ferreira 3, C?sar Nonato de Oliveira 1 READ MORE
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Solid-state NMR studies of pharmaceutical solids in polymer matrices
Votes:7 Comments:0
Solid-state NMR studies of pharmaceutical solids in polymer matrices March 2004 Joseph W. Lubach1, Brian E. Padden1, 2, Stephanie L. Winslow1, Jonathon S. Salsbury1, 3, David B. Masters1, 4, Elizabe READ MORE
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Stereochemistry of a diastereoisomeric amphiphile and the species of the lipase ...
Votes:21 Comments:0
Stereochemistry of a diastereoisomeric amphiphile and the species of the lipase influence enzyme activity in the transesterification catalyzed by a lipase-co-lyophilizate with the amphiphile in organi READ MORE
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Inactivation and Aggregation of beta-Galactosidase in Lyophilized Formulation De...
Votes:34 Comments:0
Inactivation and Aggregation of beta-Galactosidase in Lyophilized Formulation Described by Kohlrausch-Williams-Watts Stretched Exponential Function October 2003 Sumie Yoshioka1, Shinsuke Tajima1, Yu READ MORE
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Nasal delivery of human growth hormone: in vitro and in vivo evaluation of a thi...
Votes:5 Comments:0
Nasal delivery of human growth hormone: in vitro and in vivo evaluation of a thiomer/glutathione microparticulate delivery system November 2004 Verena M. Leitner, a, Davide Guggi, a, Alexander H. Kr READ MORE
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Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization...
Votes:37 Comments:0
Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres READ MORE
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Lipid-derivatized poly(ethylene glycol) micellar formulations of benzoporphyrin ...
Votes:13 Comments:0
Lipid-derivatized poly(ethylene glycol) micellar formulations of benzoporphyrin derivatives January 2003 Janny X. Zhang, Christian B. Hansen, Theresa M. Allen, Anthony Boey and Ron Boch Journal of READ MORE
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Acoustically active liposomes for drug encapsulation and ultrasound-triggered re...
Votes:26 Comments:0
Acoustically active liposomes for drug encapsulation and ultrasound-triggered release October 2004 Shao-Ling Huang and Robert C. MacDonald Biochimica et Biophysica Acta (BBA) - Biomembranes, Volum READ MORE
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Camptothecin-catalyzed phospholipid hydrolysis in liposomes
Votes:40 Comments:0
Camptothecin-catalyzed phospholipid hydrolysis in liposomes January 2005 Ann Mari S?tern, Merete Skar, ?smund Braaten and Martin Brandl International Journal of Pharmaceutics, Volume 288, Issue 1, READ MORE
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Preservation of dried liposomes in the presence of sugar and phosphate
Votes:15 Comments:0
Preservation of dried liposomes in the presence of sugar and phosphate March 2004 Willem F. Wolkers , Harri?tte Oldenhof , Fern Tablin and John H. Crowe Biochimica et Biophysica Acta (BBA) - Biomem READ MORE
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Lyophilisation and resuscitation of sporozoites of Theileria parva: preliminary ...
Votes:29 Comments:0
Lyophilisation and resuscitation of sporozoites of Theileria parva: preliminary experiments December 2003 T. Marcotty, D. Berkvens, R. K. Besa, B. Losson, T. T. Dolan, M. Madder, G. Chaka, P. Van de READ MORE
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Solid lipid nanoparticles as drug delivery systems.
Votes:37 Comments:0
Solid lipid nanoparticles as drug delivery systems. March 2005 Manjunath K, Reddy JS, Venkateswarlu V. Methods Find Exp Clin Pharmacol. 2005 Mar;27(2):127-44. PubMed You can view the abstract onl READ MORE
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Formation of Core/Shell Nanoparticles with a Lipid Core and Their Application as...
Votes:13 Comments:0
Formation of Core/Shell Nanoparticles with a Lipid Core and Their Application as a Drug Delivery System February 2005 Keun Sang Oh, Kyung Eun Lee, Sung Sik Han, Sun Hang Cho, Dongmin Kim, and Soon H READ MORE
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Caprolactonic poloxamer analog: PEG-PCL-PEG.
Votes:27 Comments:0
Caprolactonic poloxamer analog: PEG-PCL-PEG. March-April 2005 Hwang MJ, Suh JM, Bae YH, Kim SW, Jeong B. Biomacromolecules. 2005 Mar-Apr;6(2):885-90. PubMed You can view the abstract online. A s READ MORE
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Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targ...
Votes:40 Comments:0
Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting. May 13, 2005 D Bhadra, AK Yadav, S Bhadra, and NK Jain Int J Pharm, May 13, 2005; 295(1-2): 221-33. PubMed Y READ MORE
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International collaborative study to evaluate a candidate reference preparation ...
Votes:16 Comments:0
International collaborative study to evaluate a candidate reference preparation to define an appropriate specified limit of anti-D in intravenous immunoglobulin products. May 2005 Thorpe SJ, Fox B, READ MORE
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Bacillus calmette-guerin Tokyo172 substrain for superficial bladder cancer: char...
Votes:11 Comments:0
Bacillus calmette-guerin Tokyo172 substrain for superficial bladder cancer: characterization and antitumor effect. May 2005 Ikeda N, Honda I, Yano I, Koyama A, Toida I. Journal of Urology 2005 May; READ MORE
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Ultra Structure of Lyophilized Human Amniotic Membrane
Votes:5 Comments:0
Ultra Structure of Lyophilized Human Amniotic Membrane 2005 T. Rodriguez?Ares1,A, M.J. L?pez? Valladares1,A, R. Tourino Peralba1,A, B. Vieites1,B, M. Silva1,C and J. Couceiro1,C Investigative Oph READ MORE
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Cryopreserved and lyophilized cultured epidermal allografts in the treatment of ...
Votes:38 Comments:0
Cryopreserved and lyophilized cultured epidermal allografts in the treatment of leg ulcers: a pilot study March 2004 Z Navr?tilov?, V Slonkov?, V Semr?dov?*, J Adler Journal of the European Academy READ MORE
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European Concerted Action on Anticoagulation (ECAA): an assessment of a method f...
Votes:14 Comments:0
European Concerted Action on Anticoagulation (ECAA): an assessment of a method for ISI calibration of two whole blood point-of-care PT monitor systems based on lyophilized plasmas using whole blood eq READ MORE
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Glutaraldehyde-treated Bovine Pericardium: Effects of Lyophilization on Cytotoxi...
Votes:27 Comments:0
Glutaraldehyde-treated Bovine Pericardium: Effects of Lyophilization on Cytotoxicity and Residual Aldehydes August 2003 *Marina J.S. Maizato, Olga Z. Higa, M?nica B. Mathor, Maria A.P. Camillo, Patr READ MORE
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An international collaborative study to replace the 1st international standard f...
Votes:22 Comments:0
An international collaborative study to replace the 1st international standard for prekallikrein activator February 2005 C. Longstaff1, M.-E. Behr-Gross2, A. Daas2 & F. Lackner3 Vox Sanguinis Volu READ MORE
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A sensitive and rapid method to determine the viability of freeze-dried bacteria...
Votes:16 Comments:0
A sensitive and rapid method to determine the viability of freeze-dried bacterial cells June 2003 N. Parthuisot1, P. Catala1, P. Lebaron1, D. Clermont2 and C. Bizet21 Letters in Applied Microbiolog READ MORE
http://www.blackwell-synergy.com/doi/abs/10.1046/j.1472-765X.2003.0133...

Stabilization of a freeze-dried recombinant streptokinase formulation without se...
Votes:30 Comments:0
Stabilization of a freeze-dried recombinant streptokinase formulation without serum albumin August 2004 M. L?pez MSc, L. R. Gonz?lez MSc, N. Reyes MSc, J. Sotolongo MSc, V. Pujol MSc and Kethia Aroc READ MORE
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Healthcare Crisis Hits Medicare Patients Needing Immune Globulin; Medicare Moder...
Votes:24 Comments:0
Healthcare Crisis Hits Medicare Patients Needing Immune Globulin; Medicare Modernization Act Has Unintended but Devastating Repercussions for Seriously Ill Beneficiaries 16 May 05 Genetic Engineerin READ MORE
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Diclofenac B-Cyclodextrin Binary Systems: A Study in Solution and in the Solid S...
Votes:33 Comments:0
Diclofenac B-Cyclodextrin Binary Systems: A Study in Solution and in the Solid State August 2003 Francesco Barbato, Brunella Cappello, Maria Immacolata La Rotonda and Fabiana Quaglia Journal of Inc READ MORE
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Investigations into the Stabilization of Drugs by Sugar Glasses: III. The Influe...
Votes:27 Comments:0
Investigations into the Stabilization of Drugs by Sugar Glasses: III. The Influence of Various High-pH Buffers September 2003 Jonas H. C. Eriksson, Wouter L. J. Hinrichs, Gerhardus J. de Jong, Gover READ MORE
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Effect of hydroxypropylmethyl cellulose on the complexation of diclofenac with c...
Votes:3 Comments:0
Effect of hydroxypropylmethyl cellulose on the complexation of diclofenac with cyclodextrins January 2003 B. Pose-Vilarnovo, C. Rodr?guez-Tenreiro S?nchez, N. Di?guez Moure, et al. Journal of Therm READ MORE
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Intravenous drug preparation practices: a survey in a French university hospital
Votes:36 Comments:0
Intravenous drug preparation practices: a survey in a French university hospital December 2003 Patrick Tilleul, Bisserka Mons, Claude Schmitt, Jean-Marie Laporte and Dominique Begue Pharmacy World READ MORE
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Solid Lipid Nanoparticles (SLNs): Preparation and Properties of Calix[4]resorcin...
Votes:30 Comments:0
Solid Lipid Nanoparticles (SLNs): Preparation and Properties of Calix[4]resorcinarene Derived Systems. February 2004 J?r?me Gualbert, Patrick Shahgaldian, Adina Lazar and Anthony W. Coleman Journal READ MORE
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Increasing process understanding of wet granulation by spectroscopic methods and...
Votes:6 Comments:0
Increasing process understanding of wet granulation by spectroscopic methods and dimension reduction tools 2004 by Anna Cecilia J?rgensen Division of Pharmaceutical Technology Faculty of Pharmacy READ MORE
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First West Coast baby born using frozen egg technique
Votes:33 Comments:0
First West Coast baby born using frozen egg technique 7/10/2003 Bio.com The University Fertility Consultants at the Oregon Health & Science University have successfully frozen human eggs that have READ MORE
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Lytic protease can exist in two separately stable conformations with different H...
Votes:28 Comments:0
Lytic protease can exist in two separately stable conformations with different His57 mobilities and catalytic activities Kristin Coffman Haddad, James L. Sudmeier, Daniel A. Bachovchin and William W. READ MORE
http://www.pnas.org/cgi/content/abstract/102/4/1006...

Enhanced picture of protein-folding intermediates using organic solvents in H/D ...
Votes:3 Comments:0
Enhanced picture of protein-folding intermediates using organic solvents in H/D exchange and quench-flow experiments Chiaki Nishimura, H. Jane Dyson and Peter E. Wright March 29, 2005 PNAS Hydro READ MORE
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Acusphere: making speciality pharmaceuticals using porous microparticle technolo...
Votes:30 Comments:0
Acusphere: making speciality pharmaceuticals using porous microparticle technology 2005 T&F Informa UK Ltd Acusphere?s patented porous microparticle technology is being used to create new drugs an READ MORE
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UC Davis finds market for freeze-dried blood platelets
Votes:25 Comments:0
UC Davis finds market for freeze-dried blood platelets Celia Lamb February 9, 2004 Sacramento Business Journal Researchers at the University of California Davis have developed a technology for fre READ MORE
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Vaccine reconstitution and administration
Votes:28 Comments:0
Vaccine reconstitution and administration last updated 10-Jan-2005 WHO Vaccines are produced in two different forms: as a liquid, which is ready to administer, or as a freeze-dried powder that mus READ MORE
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With demand lacking, smallpox vaccine expiring
Votes:23 Comments:0
With demand lacking, smallpox vaccine expiring August 23, 2003 By Stephen Smith, Globe Staff UCLA Department of Epidemiology The Bush administration's campaign to vaccinate health workers against READ MORE
http://www.ph.ucla.edu/epi/bioter/spoxvacexpiring.html

Long-Term Efficacy of BCG Vaccine in American Indians and Alaska Natives: A 60-Y...
Votes:37 Comments:0
Long-Term Efficacy of BCG Vaccine in American Indians and Alaska Natives: A 60-Year Follow-Up Study. 2004 Commentary By Lewellys Barker, Senior Medical Advisor, Aeras Global TB Vaccine Foundatio READ MORE
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Preparation of interconnected highly porous polymeric structures by a replicatio...
Votes:12 Comments:0
Preparation of interconnected highly porous polymeric structures by a replication and freeze-drying process Published Online: 17 Oct 2003 Received: 3 September 2002; Revised: 14 March 2003; Accepted READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/106559290/ABSTRACT

Solute crystallization in mannitol-glycine systems - implications on protein sta...
Votes:26 Comments:0
Solute crystallization in mannitol-glycine systems - implications on protein stabilization in freeze-dried formulations 25 Aug 2003 Received: 17 March 2003; Revised: 9 May 2003; Accepted: 29 May 200 READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/104555427/ABSTRACT

Preparation and Structure of Porous Silk Sericin Materials
Votes:20 Comments:0
Preparation and Structure of Porous Silk Sericin Materials Published Online: 17 Mar 2005 Received: 21 October 2004; Revised: 4 January 2005; Accepted: 12 January 2005 Wei Tao, Mingzhong Li *, Ruiju READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110431304/ABSTRACT

Cryopreservation of adherent human embryonic stem cells
Votes:15 Comments:0
Cryopreservation of adherent human embryonic stem cells 14 Oct 2004 Received: 18 December 2003; Accepted: 16 June 2004 Lin Ji, Juan J. de Pablo, Sean P. Palecek * Biotechnology and Bioengineering READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/109712564/ABSTRACT

Effect of freezing and thawing rates on denaturation of proteins in aqueous solu...
Votes:29 Comments:0
Effect of freezing and thawing rates on denaturation of proteins in aqueous solutions Published Online: 24 Mar 2003 Received: 11 July 2002; Accepted: 7 November 2002 Enhong Cao 1, Yahuei Chen 1, Zh READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/104085740/ABSTRACT

Hydroxyapatite and gelatin composite foams processed via novel freeze-drying and...
Votes:4 Comments:0
Hydroxyapatite and gelatin composite foams processed via novel freeze-drying and crosslinking for use as temporary hard tissue scaffolds Published Online: 17 Nov 2004 Received: 11 November 2003; Rev READ MORE
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Relationship between encapsulated drug particle size and initial release of reco...
Votes:18 Comments:0
Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres Published Online: 24 Aug 2004 Received: 6 August 2003; Re READ MORE
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Structure and Properties of Poly(vinyl alcohol) Hydrogels Obtained by Freeze/Tha...
Votes:13 Comments:0
Structure and Properties of Poly(vinyl alcohol) Hydrogels Obtained by Freeze/Thaw Techniques Published Online: 13 Apr 2005 Rosa Ricciardi, Finizia Auriemma, Claudio De Rosa * Macromolecular Symposi READ MORE
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Production of precise microbiology standards using flow cytometry and freeze dry...
Votes:26 Comments:0
Production of precise microbiology standards using flow cytometry and freeze drying Published Online: 31 Oct 2004 Received: 30 September 2003; Revised: 18 March 2004; Accepted: 21 April 2004 C. A. READ MORE
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Synthesis and characterization of hexagonal ferrites BaFe12-2xZnxTixO19 (0 x 2...
Votes:15 Comments:0
Synthesis and characterization of hexagonal ferrites BaFe12-2xZnxTixO19 (0 x 2) by thermal decomposition of freeze-dried precursors Published Online: 2 Oct 2003 Received: 15 April 2003; Accepted: READ MORE
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Differential scanning calorimetry study on thermal behaviors of freeze-dried pol...
Votes:10 Comments:0
Differential scanning calorimetry study on thermal behaviors of freeze-dried poly(L-lactide) from dilute solutions Published Online: 18 Nov 2004 Received: 8 June 2004; Revised: 31 August 2004; Accep READ MORE
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Evaluation of platelet-rich plasma in combination with freeze-dried bone in the ...
Votes:24 Comments:0
Evaluation of platelet-rich plasma in combination with freeze-dried bone in the rabbit cranium April 2005 Tara L. Aghaloo1, Peter K. Moy2 and Earl G. Freymiller11 Clinical Oral Implants Research V READ MORE
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Use of glycerol as an alternative to freeze-drying for long-term preservation of...
Votes:37 Comments:0
Use of glycerol as an alternative to freeze-drying for long-term preservation of antigen for the direct agglutination test November 2003 Abdallah el Harith1,2, Mohamed el Mutasim2, Durria Mansour2, READ MORE
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Drying of Epicoccum nigrum conidia for obtaining a shelf-stable biological produ...
Votes:13 Comments:0
Drying of Epicoccum nigrum conidia for obtaining a shelf-stable biological product against brown rot disease March 2003 I. Larena, A. De Cal, M. Li??n and P. Melgarejo Journal of Applied Microbiolo READ MORE
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Effect of various growth media upon survival during storage of freeze-dried Ente...
Votes:27 Comments:0
Effect of various growth media upon survival during storage of freeze-dried Enterococcus faecalis and Enterococcus durans June 2003 A.S. Carvalho1, J. Silva1, P. Ho1,2, P. Teixeira1, F.X. Malcata1 a READ MORE
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Collaborative studies to establish the first WHO Reference Reagent for detection...
Votes:21 Comments:0
Collaborative studies to establish the first WHO Reference Reagent for detection of human antibody against human platelet antigen-5b April 2003 P. Metcalfe1, W. H. Ouwehand1,3, D. Sands2 & T. W. Bar READ MORE
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The maintenance and preservation of keratinophilic fungi and related dermatophyt...
Votes:16 Comments:0
The maintenance and preservation of keratinophilic fungi and related dermatophytes June 2003 S. K. DeshmukhDepartment of Applied Microbiology and Biotechnology, Dr H.S. Gour Vishwavidyalaya, Sagar, READ MORE
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Ca2+-Dependent Elevation of Inositol 1,4,5-Trisphosphate Level Induced by Freezi...
Votes:10 Comments:0
Ca2+-Dependent Elevation of Inositol 1,4,5-Trisphosphate Level Induced by Freezing or Homogenization of Tissues and Cells December 2004 Dagny Sandnes, Laila Sortvik Nilssen, Geir ?ystein Andersen, H READ MORE
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Evaluation of the direct agglutination test based on freeze-dried Leishmania don...
Votes:24 Comments:0
Evaluation of the direct agglutination test based on freeze-dried Leishmania donovani promastigotes for the serodiagnosis of visceral leishmaniasis in Sudanese patients October 2004 Khalid A. A. Abd READ MORE
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Guidelines on preparation, certification, and use of certified plasmas for ISI c...
Votes:19 Comments:0
Guidelines on preparation, certification, and use of certified plasmas for ISI calibration and INR determination November 2004 A. M. H. P. Van Den Besselaar, T. W. Barrowcliffe*, L. L. Houbouyan-R?v READ MORE
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Mechanical and Structural Properties of a Novel Hybrid Heart Valve Scaffold for ...
Votes:13 Comments:0
Mechanical and Structural Properties of a Novel Hybrid Heart Valve Scaffold for Tissue Engineering November 2004 Niels Grabow*, Kathleen Schmohl*, Amir Khosravi, Mark Philipp, Michael Scharfschwerdt READ MORE
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Evaluation of demineralized bone matrix paste and putty in periodontal intraosse...
Votes:27 Comments:0
Evaluation of demineralized bone matrix paste and putty in periodontal intraosseous defects. 2005 May Bender SA, Rogalski JB, Mills MP, Arnold RM, Cochran DL, Mellonig JT. J Periodontol. PubMed P READ MORE
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Physical characterisation of formulations for the development of two stable free...
Votes:3 Comments:0
Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage Received 19 October 2004; accepted 23 February 2005. Availabl READ MORE
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Development of a high-throughput method for preparing human urine for two-dimens...
Votes:16 Comments:0
Development of a high-throughput method for preparing human urine for two-dimensional electrophoresis 11 May 2005 Received: 20 August 2004 Graeme Smith 1 *, Derek Barratt 2, Rachel Rowlinson 1, Jan READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110492674/ABSTRACT

Relation between Storage Temperature and Fertilizing Ability of Freeze-Dried Mou...
Votes:11 Comments:0
Relation between Storage Temperature and Fertilizing Ability of Freeze-Dried Mouse Spermatozoa. 2005 Apr Kaneko T, Nakagata N. Comp Med. PubMed Division of Reproductive Engineering, Center for A READ MORE
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Stabilities of Artificially Transconjugated Plasmids for the Bioremediation of C...
Votes:5 Comments:0
Stabilities of Artificially Transconjugated Plasmids for the Bioremediation of Cocontaminated Sites 2005 Kyung Pyo Yoon* The Journal of Microbiology Address Department of Microbiology, Keimyung Un READ MORE
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Disulfide-crosslinked hyaluronan-gelatin sponge: Growth of fibrous tissue in viv...
Votes:38 Comments:0
Disulfide-crosslinked hyaluronan-gelatin sponge: Growth of fibrous tissue in vivo Nov 2003 Received: 23 January 2003; Revised: 18 April 2003; Accepted: 21 July 2003 Yanchun Liu 1, Xiao Zheng Shu 1, READ MORE
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Establishment of a near-standard two-dimensional human urine proteomic map
Votes:33 Comments:0
Establishment of a near-standard two-dimensional human urine proteomic map 4 Nov 2004 Received: 27 April 2004 Jisun Oh 1, Jae-Hoon Pyo 1, Eun-Hyun Jo 1, Sun-Il Hwang 4, Sun-Chul Kang 3, Jae-Hwan Ju READ MORE
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Formulation of a freeze-dried kit for 188Re-MAG3 and its quality control
Votes:14 Comments:0
Formulation of a freeze-dried kit for 188Re-MAG3 and its quality control August 2003 S. Pervez1, A. Mushtaq1 and M. Arif2 Journal of Radioanalytical and Nuclear Chemistry Issue: Volume 257, Num READ MORE
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Evaluation of Freeze-Dried Dura Mater Allograft as a Collagen Based Barrier (an ...
Votes:9 Comments:0
Evaluation of Freeze-Dried Dura Mater Allograft as a Collagen Based Barrier (an experimental animal study) June 2003 A.V. Shah1 and B.S. Jathal2 Cell and Tissue Banking Issue: Volume 4, Numbers READ MORE
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Freeze drying of cryogranules of salts of ferrite-forming components on a finned...
Votes:22 Comments:0
Freeze drying of cryogranules of salts of ferrite-forming components on a finned surface September 2004 V. I. Gulevich1, S. M. Brazhnikov2 and A. Z. Volynets2 Chemical and Petroleum Engineering READ MORE
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Medium-term follow-up on use of freeze-dried, irradiated donor fascia for sacroc...
Votes:36 Comments:0
Medium-term follow-up on use of freeze-dried, irradiated donor fascia for sacrocolpopexy and sling procedures August 2004 Received: 8 November 2002 Accepted: 3 March 2003 Published online: 14 May READ MORE
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Development of an Injectable Formulation for the Novel Lipid A Analog E5531 Usin...
Votes:30 Comments:0
Development of an Injectable Formulation for the Novel Lipid A Analog E5531 Using a ?pH-jump Method' (Received June 28, 2004) (Accepted August 19, 2004) Yasuyuki ASAI1 YAKUGAKU ZASSHI Vol. 124 ( READ MORE
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Bacterial ghosts as antigen delivery vehicles
Votes:25 Comments:0
Bacterial ghosts as antigen delivery vehicles Received 31 January 2004; accepted 25 January 2005. Available online 20 April 2005. Ulrike Beate Mayra, Petra Walchera, Chakameh Azimpoura, Eva Ried READ MORE
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Establishment of batch 4 of the Biological Reference Preparation (BRP) for rabie...
Votes:20 Comments:0
Establishment of batch 4 of the Biological Reference Preparation (BRP) for rabies vaccine (inactivated) for veterinary use. 2004 Dec;2004 Daas A, Milne C. Pharmeuropa Bio PubMed European Director READ MORE
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Stability of mono- and trivalent meningococcal outer membrane vesicle vaccines
Votes:33 Comments:0
Stability of mono- and trivalent meningococcal outer membrane vesicle vaccines 26 January 2004 Received 27 February 2003; revised 27 August 2003; accepted 27 August 2003. ; Available online 14 Oc READ MORE
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Collaborative study for establishment of the European Pharmacopoeia BRP batch 1 ...
Votes:28 Comments:0
Collaborative study for establishment of the European Pharmacopoeia BRP batch 1 for diphtheria toxin. 2003 Jul Sesardic D, Prior C, Daas A, Buchheit KH Pharmeuropa Bio PubMed NATIONAL INSTITUTE F READ MORE
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ImmuCyst intravesical (freeze-dried preparation made from the connaught strain o...
Votes:4 Comments:0
ImmuCyst intravesical (freeze-dried preparation made from the connaught strain of Bacillus Calmette Guerin) for the treatment of superficial bladder cancer and carcinoma in situ of urinary bladder 20 READ MORE
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Extended freeze-dried Mycobacterium bovis Bacillus CalmetteGu?rin induces the re...
Votes:17 Comments:0
Extended freeze-dried Mycobacterium bovis Bacillus CalmetteGu?rin induces the release of interleukin-12 but not tumour necrosis factor- by alveolar macrophages, both in vitro and in vivo March 2003 READ MORE
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Freeze-drying for IVDs
Votes:12 Comments:0
Freeze-drying for IVDs Originally Published IVD Technology June 2004 medical devicelink Advances in automation have imparted greater control over the lyophilization process. For reagents that are READ MORE
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Stability of reconstituted parecoxib for injection with commonly used diluents
Votes:33 Comments:0
Stability of reconstituted parecoxib for injection with commonly used diluents October 2003 I. M. Crane BS, M. G. Mulhern BS and S. Nema PhD, Pfizer Inc., Skokie, IL, USA Journal of Clinical Pharma READ MORE
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Cryoprotection Mechanisms of Polyethylene Glycols on Lactate Dehydrogenase Durin...
Votes:9 Comments:0
Cryoprotection Mechanisms of Polyethylene Glycols on Lactate Dehydrogenase During Freeze-thawing September 2004 Yanli Mi, George Wood,2 and Laura Thoma The AAPS Journal 2004; 6 (3) Article 22 You READ MORE
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Stable Amorphous Danazol Nanostructured Powders with Rapid Dissolution Rates Pro...
Votes:23 Comments:0
Stable Amorphous Danazol Nanostructured Powders with Rapid Dissolution Rates Produced by Spray Freezing into Liquid September 2004 Jiahui Hu, Keith P. Johnston and Robert O. Williams, III Drug Dev READ MORE
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Direct observation of the enthalpy relaxation and the recovery processes of malt...
Votes:17 Comments:0
Direct observation of the enthalpy relaxation and the recovery processes of maltose-based amorphous formulation by isothermal microcalorimetry. September 2003 Kawakami K, Ida Y., Developmental Resea READ MORE
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Report of a WHO workshop on the standardization and control of antivenoms.
Votes:12 Comments:0
Report of a WHO workshop on the standardization and control of antivenoms. April 2003 Theakston RD, Warrell DA, Griffiths E., Alistair Reid Venom Research Unit, WHO Collaborating Centre for the Cont READ MORE
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Enhancement of the release of azelaic acid through the synthetic membranes by in...
Votes:26 Comments:0
Enhancement of the release of azelaic acid through the synthetic membranes by inclusion complex formation with hydroxypropyl-beta-cyclodextrin. April 2005 Manosroi J, Apriyani MG, Foe K, Manosroi A. READ MORE
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The application of non-contact laser profilometry to the determination of perman...
Votes:26 Comments:0
The application of non-contact laser profilometry to the determination of permanent structural change induced by compaction of pellets II. Pellets dried by different techniques May 2004 Received 2 READ MORE
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A study on the effect of drying techniques on the mechanical properties of pelle...
Votes:21 Comments:0
A study on the effect of drying techniques on the mechanical properties of pellets and compacted pellets February 2004 Received 10 February 2003; revised 9 September 2003; accepted 17 September 2 READ MORE
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The effect of pH and triethanolamine on sulfisoxazole complexation with hydroxyp...
Votes:15 Comments:0
The effect of pH and triethanolamine on sulfisoxazole complexation with hydroxypropyl--cyclodextrin November 2003 Received 9 September 2002; revised 10 June 2003; accepted 15 July 2003. ; Availab READ MORE
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Engineered microcrystals for direct surface modification with layer-by-layer tec...
Votes:10 Comments:0
Engineered microcrystals for direct surface modification with layer-by-layer technique for optimized dissolution November 2004 Received 29 October 2003; Revised 3 May 2004; accepted 3 May 2004. READ MORE
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The influence of the use of viscosifying agents as dispersion media on the drug ...
Votes:4 Comments:0
The influence of the use of viscosifying agents as dispersion media on the drug release properties from PLGA nanoparticles November 2004 Received 12 December 2003; Revised 22 March 2004; accepted READ MORE
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A study of the freeze-drying conditions of calixarene based solid lipid nanopart...
Votes:37 Comments:0
A study of the freeze-drying conditions of calixarene based solid lipid nanoparticles March 2003 Received 15 August 2002; revised 20 December 2002; accepted 20 December 2002. ; Available online 8 READ MORE
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Sustained buccal delivery of the hydrophobic drug denbufylline using physically ...
Votes:13 Comments:0
Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels January 2003 Lee Martin a, Clive G. Wilson a, Fariba Koosha b and Ij READ MORE
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Bacteriophage lambda is a highly stable DNA vaccine delivery vehicle
Votes:26 Comments:0
Bacteriophage lambda is a highly stable DNA vaccine delivery vehicle June 2004 Catherine D. Jepson and John B. March, Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ READ MORE
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Preparation and characterization of SARS in-house reference antiserum
Votes:40 Comments:0
Preparation and characterization of SARS in-house reference antiserum March 2005 Jiansan Zhang, Yuxuan Liu, Liangxiang Hu, Qiang Gao, Zhenshan Zhang, Xiaomei Zhang, Jiangting Chen, Xuejie Gong, READ MORE
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Virus-like particle expression and assembly in plants: hepatitis B and Norwalk v...
Votes:15 Comments:0
Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses March 2005 Zhong Huang, Galina Elkin, Bryan J. Maloney, Norene Beuhner, Charles J. Arntzen, Yasmin Thanavala an READ MORE
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Antigen discovery and delivery of subunit vaccines by nonliving bacterial ghost ...
Votes:29 Comments:0
Antigen discovery and delivery of subunit vaccines by nonliving bacterial ghost vectors. December 2004 Walcher P, Mayr UB, Azimpour-Tabrizi C, Eko FO, Jechlinger W, Mayrhofer P, Alefantis T, Mujer C READ MORE
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Post-thaw aging affects activity of lactate dehydrogenase
Votes:5 Comments:0
Post-thaw aging affects activity of lactate dehydrogenase April 2005 Bakul S. Bhatnagar, Sarah J. Nehm, Michael J. Pikal, Robin H. Bogner Journal of Pharmaceutical Sciences, Volume 94, Issue 6, Dat READ MORE
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Effects of acidic N + 1 residues on asparagine deamidation rates in solution and...
Votes:18 Comments:0
Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state January 2005 Bei Li 1, Eric M. Gorman 2, Kimberly D. Moore 3, Todd Williams 3, Richard L. Schowen READ MORE
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Effect of the covalent modification with poly(ethylene glycol) on a-chymotrypsin...
Votes:13 Comments:0
Effect of the covalent modification with poly(ethylene glycol) on a-chymotrypsin stability upon encapsulation in poly(lactic-co-glycolic) microspheres November 2004 Ingrid J. Castellanos 1, Wasfi Al READ MORE
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Heterogeneous nucleation-controlled particulate formation of recombinant human p...
Votes:27 Comments:0
Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation November 2004 Eva Y. Chi 1, Joachim Weickmann READ MORE
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Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy
Votes:40 Comments:0
Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy July 2004 Shu Jun Bai 1, Meena Rani 2, Raj Suryanarayanan 2, John F. Carpenter 1, Rajiv Nayar 3, Mark C. Manning 1 4 * 1C READ MORE
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The Stability of lyophilized lipid/DNA complexes during prolonged storage
Votes:35 Comments:0
The Stability of lyophilized lipid/DNA complexes during prolonged storage June 2004 Marion d.C. Molina, Taylor K. Armstrong, Ye Zhang, Mayank M. Patel, Yvonne K. Lentz, Thomas J. Anchordoquy Center READ MORE
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Infrared spectroscopic studies of protein formulations containing glycine
Votes:10 Comments:0
Infrared spectroscopic studies of protein formulations containing glycine March 2004 Jeffrey D. Meyer 1, Shu Jun Bai 1, Meena Rani 2, Raj Suryanarayanan 2, Rajiv Nayar 3, John F. Carpenter 1, Mark C READ MORE
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Temperature- and glass transition temperature-dependence of bimolecular reaction...
Votes:5 Comments:0
Temperature- and glass transition temperature-dependence of bimolecular reaction rates in lyophilized formulations described by the Adam-Gibbs-Vogel equation February 2004 Sumie Yoshioka, Yukio Aso, READ MORE
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Acid-base characteristics of bromophenol blue-citrate buffer systems in the amor...
Votes:38 Comments:0
Acid-base characteristics of bromophenol blue-citrate buffer systems in the amorphous state December 2003 Jinjiang Li 1, Koustuv Chatterjee 2, Ales Medek 2, Evgenyi Shalaev 2, George Zografi 1 * 1S READ MORE
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Effects of potassium bromide disk formation on the infrared spectra of dried mod...
Votes:13 Comments:0
Effects of potassium bromide disk formation on the infrared spectra of dried model proteins December 2003 Jeffrey D. Meyer, Mark C. Manning John F. Carpenter, Center for Pharmaceutical Biotechnolog READ MORE
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An investigation into the subambient behavior of aqueous mannitol solutions usin...
Votes:8 Comments:0
An investigation into the subambient behavior of aqueous mannitol solutions using differential scanning calorimetry, cold stage microscopy, and X-ray diffractometry June 2003 icky L. Kett 1, Shaun F READ MORE
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Physicochemical studies on the stability of influenza haemagglutinin in vaccine ...
Votes:40 Comments:0
Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material. September 2004 Luykx DM, Casteleijn MG, Jiskoot W, Westdijk J, Jongen PM., Center for Biological Medici READ MORE
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Pharmacokinetics of Paclitaxel-Containing Liposomes in Rats
Votes:11 Comments:0
Pharmacokinetics of Paclitaxel-Containing Liposomes in Rats November 2003 Gerald J. Fetterly1,2 and Robert M. Straubinger1 1Department of Pharmaceutical Sciences, University at Buffalo, State Univ READ MORE
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Salt-activation of nonhydrolase enzymes for use in organic solvents
Votes:11 Comments:0
Salt-activation of nonhydrolase enzymes for use in organic solvents 31 Dec 2003 John A. Morgan, Douglas S. Clark Biotechnology and Bioengineering Abstract Enzymatic reactions are important for t READ MORE
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Combinatorial formulation of biocatalyst preparations for increased activity in ...
Votes:6 Comments:0
Combinatorial formulation of biocatalyst preparations for increased activity in organic solvents: Salt activation of penicillin amidase January 2004 John P. Lindsay , Douglas S. Clark, Jonathan S. READ MORE
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Comparison of theoretical and experimental data to evaluate substrate diffusiona...
Votes:38 Comments:0
Comparison of theoretical and experimental data to evaluate substrate diffusional limitations for crown ether- and methyl--cyclodextrin-activated serine protease subtilisin Carlsberg in tetrahydrofura READ MORE
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The Protective Effect Of Lactose On Lyophilization Of CNK-20402
Votes:33 Comments:0
The Protective Effect Of Lactose On Lyophilization Of CNK-20402 Accepted September 16, 2004, Author's Final Version Yung-Chi Lee*, Jared Nelson, Katsuhiko Sueda, Donna Seibert, Wen-Yaw Hsieh, Bryan READ MORE
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Preparation and analysis of 99mTc moxifloxacin as an infection specific imaging ...
Votes:28 Comments:0
Preparation and analysis of 99mTc moxifloxacin as an infection specific imaging agent. Kashani, R.; Cooper, M.S.; Das, S.S. April 2004 Nuclear Medicine Communications. 25(4):413-414 This is a subs READ MORE
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Combined administration of meningococcal serogroup B outer membrane vesicle vacc...
Votes:17 Comments:0
Combined administration of meningococcal serogroup B outer membrane vesicle vaccine and conjugated serogroup C vaccine indicated for prevention of meningococcal disease is safe and immunogenic. May 1 READ MORE
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Antiallergic and antihistaminic effect of two extracts of Capparis spinosa L. fl...
Votes:30 Comments:0
Antiallergic and antihistaminic effect of two extracts of Capparis spinosa L. flowering buds March 30, 2005 Domenico Trombetta 1 *, Francesco Occhiuto 1, Daniela Perri 1, Carmelo Puglia 2, Natale A. READ MORE
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World Health Organization collaborative study to establish a replacement WHO int...
Votes:25 Comments:0
World Health Organization collaborative study to establish a replacement WHO international standard for hepatitis C virus RNA nucleic acid amplification technology assays. April 2005 Saldanha J, Hea READ MORE
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Dose?response effects of Lepidium meyenii (Maca) aqueous extract on testicular f...
Votes:33 Comments:0
Dose?response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats April 2005 Francisco Chung, Julio Rubio, Carla Gonzales, Manuel G READ MORE
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Effect of Sapindus trifoliatus on hyperalgesic in vivo migraine models
Votes:9 Comments:0
Effect of Sapindus trifoliatus on hyperalgesic in vivo migraine models March 2005 D.K. Arulmozhi1,2, A. Veeranjaneyulu1, S.L. Bodhankar2 and S.K. Arora1 1New Chemical Entity Research, Lupin Researc READ MORE
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Hepatoprotective effects of the water extract from adzuki bean hulls on acetamin...
Votes:4 Comments:0
Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver. October 2004 Han KH, Fukushima M, Ohba K, Shimada K, Sekikawa M, Chiji H, Lee CH, N READ MORE
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The production and evaluation of a standard diagnostic peste des petits ruminant...
Votes:17 Comments:0
The production and evaluation of a standard diagnostic peste des petits ruminants (PPR) hyperimmune serum prepared from the Egyptian antigen (Egypt 87). 2004 Nahed AK, Hanan SA, Hanan MS, Laila AS, READ MORE
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Single-step purification of lipase from Burkholderia multivorans using polypropy...
Votes:12 Comments:0
Single-step purification of lipase from Burkholderia multivorans using polypropylene matrix February 2005 Gupta N, Rathi P, Singh R, Goswami VK, Gupta R., Department of Microbiology, University of READ MORE
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Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two ma...
Votes:6 Comments:0
Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins, BthTX-I and BthTX-II, by the aqueous extract of Tabernaemontana catharinensis A. DC. (Apocynaceae). Janu READ MORE
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Artificial Cell Therapy: New Strategies for the Therapeutic Delivery of Live Bac...
Votes:39 Comments:0
Artificial Cell Therapy: New Strategies for the Therapeutic Delivery of Live Bacteria. 2005 Prakash S, Jones ML. J Biomed Biotechnol. 2005;2005(1):44-56. There has been rapid growth in research re READ MORE
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Inhibition of Human Lanosterol Synthase by the Constituents of Colocasia esculen...
Votes:34 Comments:0
Inhibition of Human Lanosterol Synthase by the Constituents of Colocasia esculenta (Taro) February 2005 Yuichi Sakano1), Motoh Mutsuga2), Rie Tanaka2), Hiroyuki Suganuma3), Takahiro Inakuma3), Masat READ MORE
http://www.jstage.jst.go.jp/article/bpb/28/2/28_299/_article

Sustained interferon-gamma delivery from a photocrosslinked biodegradable elasto...
Votes:9 Comments:0
Sustained interferon-gamma delivery from a photocrosslinked biodegradable elastomer. February 2005 Gu F, a, Younes HM, b, El-Kadi AO, b, Neufeld RJ, a, Amsden BG. a,b a Department of Chemical Engin READ MORE
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Large-scale production and properties of human plasma-derived activated Factor V...
Votes:23 Comments:0
Large-scale production and properties of human plasma-derived activated Factor VII concentrate January 2003 K. Tomokiyo, H. Yano, M. Imamura, Y. Nakano, T. Nakagaki, Y. Ogata, T. Terano, S. Miyamoto READ MORE
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Comparison of Botulinum Toxins A and B in the Aesthetic Treatment of Facial Rhyt...
Votes:37 Comments:0
Comparison of Botulinum Toxins A and B in the Aesthetic Treatment of Facial Rhytides April 2003 Neil S. Sadick MD FACP FAACS, and Alysa R. Herman MDDepartment of Dermatology, Weill Medical College-C READ MORE
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Efficacy of Tissue Plasminogen Activator for Thrombolysis in Central Venous Dial...
Votes:31 Comments:0
Efficacy of Tissue Plasminogen Activator for Thrombolysis in Central Venous Dialysis Catheters April 2003 Neeta B. O'Mara1, Samina Ali2, Kathleen Bivens1, Richard A. Sherman3, Toros Kapoian3 1 Dial READ MORE
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A global standard for anti-D immunoglobulin: international collaborative study t...
Votes:7 Comments:0
A global standard for anti-D immunoglobulin: international collaborative study to evaluate a candidate preparation November 2003 S. J. Thorpe1, D. Sands1, B. Fox1, M.-E. Behr-Gross2, G. Sch?ffner3 & READ MORE
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A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms...
Votes:20 Comments:0
A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndrome April 2003 H. J. Kim, M. Camilleri, S. Mckinzie, M. B. Lempke, D. D READ MORE
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Survival analysis of patients with haemophilia at the International Haemophilia ...
Votes:10 Comments:0
Survival analysis of patients with haemophilia at the International Haemophilia Training Centre, Bangkok, Thailand September 2004 A. Chuansumrit*, S. Krasaesub+, P. Angchaisuksiri, P. Hathirat* and READ MORE
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Canine serum immunoreactivity to Malassezia pachydermatis is influenced by the p...
Votes:23 Comments:0
Canine serum immunoreactivity to Malassezia pachydermatis is influenced by the phase of growth in vitro August 2004 A. Habibah, B. Catchpole and R. BondRoyal Veterinary College, University of London READ MORE
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In vitro study of a triple-secured von Willebrand factor concentrate
Votes:18 Comments:0
In vitro study of a triple-secured von Willebrand factor concentrate February 2004 C. Mazurier, M. Poulle, B. Samor, L. Hilbert & S. Chtourou Laboratoire fran?ais du Fractionnement et des Biotechno READ MORE
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Investigation of optimal manufacturing process for freeze-dried formulations: Ob...
Votes:12 Comments:0
Investigation of optimal manufacturing process for freeze-dried formulations: Observation of frozen solutions by low temperature X-ray diffraction measurements Hiroaki Egawa, Etsuo Yonemochi and Kat READ MORE
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Crystallization and X-ray diffraction of spray-dried and freeze-dried amorphous ...
Votes:7 Comments:0
Crystallization and X-ray diffraction of spray-dried and freeze-dried amorphous lactose February 2005 Md. Kamrul Haque and Yrj? H. RoosCorresponding, Department of Food and Nutritional Sciences, Un READ MORE
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Altered chemical and biological activities of all-trans retinoic acid incorporat...
Votes:40 Comments:0
Altered chemical and biological activities of all-trans retinoic acid incorporated in solid lipid nanoparticle powders November 2004 Soo-Jeong Lima, Mi-Kyung Leeb and Chong-Kook Kimb, aResearch In READ MORE
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Stabilization of DNA utilizing divalent cations and alcohol
Votes:29 Comments:0
Stabilization of DNA utilizing divalent cations and alcohol October 2003 Jefferson D. Knight 1, and Roger C. Adami Department of Pharmaceutical Research and Development, Pfizer Global Research and READ MORE
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Lyophilised wafers as a drug delivery system for wound healing containing methyl...
Votes:24 Comments:0
Lyophilised wafers as a drug delivery system for wound healing containing methylcellulose as a viscosity modifier January 2005 K.H. Matthewsa, H.N.E. Stevensa, A.D. Auffretb, M.J. Humphreyb and G.M READ MORE
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Effect of inorganic salts on crystallization of poly(ethylene glycol) in frozen ...
Votes:18 Comments:0
Effect of inorganic salts on crystallization of poly(ethylene glycol) in frozen solutions January 2005 Ken-ichi Izutsu and Nobuo Aoyagi, National Institute of Health Sciences, Kamiyoga 1-18-1, Setag READ MORE
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Rubber Stopper Quality and Technical Issues: A Global Perspective
Votes:32 Comments:0
Rubber Stopper Quality and Technical Issues: A Global Perspective March 2005 Frances L. DeGrazio Vice President, Quality Assurance and Regulatory Affairs, Americas West Pharmaceutical Services, Inc. READ MORE
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A STUDY OF THE CONFORMATIONAL STABILITY OF PROTEINS IN HYDROFLUOROALKANE PROPELL...
Votes:7 Comments:0
A STUDY OF THE CONFORMATIONAL STABILITY OF PROTEINS IN HYDROFLUOROALKANE PROPELLANTS USING FT-RAMAN SPECTROSCOPY. ?.?.Quinn1 , R.T.Forbes1 , A.C.Williams1 , M.J.Oliver2 and T.S.Purewal2 . 1Drug Deli READ MORE
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ACAMBIS PLC - Acquisition
Votes:9 Comments:0
ACAMBIS PLC - Acquisition 5/10/2005 PR Newswire UK Disclose Acambis expands manufacturing capability with acquisition of US-based fill/ finish facility Cambridge, UK and Cambridge, Massachuset READ MORE
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NA FEA MED US Polio Vaccine
Votes:3 Comments:0
NA FEA MED US Polio Vaccine MARILYNN MARCHIONE, AP Medical Writer 4/10/2005 AP Worldstream MARILYNN MARCHIONE, AP Medical Writer AP Worldstream 04-10-2005 Dateline: MILWAUKEE Dan Wilson r READ MORE
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Biotech potato provides hepatitis vaccine
Votes:20 Comments:0
Biotech potato provides hepatitis vaccine MIKE TONER 2/15/2005 The Atlanta Journal and Constitution Researchers reported Monday that potatoes genetically modified to carry a vaccine against hepati READ MORE
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Oral vector vaccines target biothreats
Votes:14 Comments:0
Oral vector vaccines target biothreats Chiarello, Kaylynn 6/1/2004 Pharmaceutical Technology Since the 2001 terrorist attacks in the United States, U.S. governmental agencies have funded numerous READ MORE
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BIOTERRORISM: Anthrax Powder: State of the Art?
Votes:9 Comments:0
BIOTERRORISM: Anthrax Powder: State of the Art? Matsumoto, Gary 11/28/2003 Science Although the investigation seems focused on the idea that the anthrax powder contained in the letters sent to th READ MORE
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Products for tomorrow
Votes:4 Comments:0
Products for tomorrow: how are some medical device companies developing next-generation designs? And how are they bridging the gap between a niche idea and an innovative premium product? In many cases READ MORE
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Coolers provide continuous cooling as low as -45 C
Votes:17 Comments:0
Coolers provide continuous cooling as low as -45 C 3/1/2005 Laboratory Equipment The KR Series Coolers offers four low-temperature units that can be used to achieve low temperature capability with READ MORE
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Tray dryer pre-freezes samples/stoppers and multiple vials under vacuum
Votes:7 Comments:0
Tray dryer pre-freezes samples/stoppers and multiple vials under vacuum 1/1/2005 Pharmaceutical Processing The stoppering tray dryer for use with the company's FreeZone 6, 12 and 18 Liter Freeze Dr READ MORE
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Activation of subtilisin Carlsberg in hexane by lyophilization in the presence o...
Votes:34 Comments:0
Activation of subtilisin Carlsberg in hexane by lyophilization in the presence of fumed silica Kerstin W?rgesb, Peter H. Pfromma, , , Mary E. Rezac and Peter Czermak 17 May 2005 Journal of Molecula READ MORE
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Method to Remove Virus from Bones, Tissues for Transplants Questioned
Votes:28 Comments:0
Method to Remove Virus from Bones, Tissues for Transplants Questioned 30 Mar 2004 Michigan State University newswise A method once thought to inactivate retroviruses such as HIV from bones and con READ MORE
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New Storage Method Amplifies Cells Available for Science
Votes:23 Comments:0
New Storage Method Amplifies Cells Available for Science 30 Mar 2004 University of Wisconsin-Madison newswise Like many other kinds of cells used in biomedical research, human embryonic stem cells READ MORE
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Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody
Votes:18 Comments:0
Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody By: Moss JA, Coyle AR, Ahn JM, Meijler MM, Offer J, Janda KD. - Department of Chemistry, The Scripps Research Institute and The Skagg READ MORE
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Stereochemistry of a diastereoisomeric amphiphile and the species of the lipase ...
Votes:12 Comments:0
Stereochemistry of a diastereoisomeric amphiphile and the species of the lipase influence enzyme activity in the transesterification catalyzed by a lipase-co-lyophilizate with the amphiphile in organi READ MORE
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Calorimetric investigation of the structural relaxation of amorphous materials: ...
Votes:7 Comments:0
Calorimetric investigation of the structural relaxation of amorphous materials: Evaluating validity of the methodologies By: Kawakami K, Pikal MJ. - Department of Pharmaceutical Sciences, School of READ MORE
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An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+...
Votes:39 Comments:0
An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit By: Christ T, Wust M, Matthes J, Janchen M, Jurgens S, Herzig S READ MORE
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Vaccines Preserved with AVANT Immunotherapeutics' VitriLife Technology Show Good...
Votes:15 Comments:0
Vaccines Preserved with AVANT Immunotherapeutics' VitriLife Technology Show Good Stability at Room Temperature and Above 5/12/2004 VertMarkets, Inc. 5/12/2004 Data to be presented by AVANT Immunot READ MORE
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Toward the development of an injectable dosage form of propofol: preparation and...
Votes:29 Comments:0
Toward the development of an injectable dosage form of propofol: preparation and evaluation of propofol-sulfobutyl ether 7-beta-cyclodextrin complex Babu MK, Godiwala TN. 2004 Aug;9 Pharm Dev Techn READ MORE
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Application of frequency-modulated spectroscopy in vacuum seal integrity testing...
Votes:23 Comments:0
Application of frequency-modulated spectroscopy in vacuum seal integrity testing of lyophilized biological products Lin TP, Hsu CC, Kabakoff BD, Patapoff TW. 2004 Mar-Apr;58 PDA J Pharm Sci Technol READ MORE
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Allergen Immunotherapy
Votes:18 Comments:0
Allergen Immunotherapy August 15, 2004 JENNIFER L. HUGGINS, M.D., and R. JOHN LOONEY, M.D. American Academy of Family Physicians Allergen immunotherapy (also called allergy vaccine therapy) involv READ MORE
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Genevac speeds up lab-scale freeze-drying
Votes:31 Comments:0
Genevac speeds up lab-scale freeze-drying 16/05/2005 NOVIS 16/05/2005 - Genevac has introduced new technology for its Model HT-4X centrifugal evaporator whereby the system can be used to accelerat READ MORE
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Liquid nitrogen technology benefits freeze-dryers
Votes:7 Comments:0
Liquid nitrogen technology benefits freeze-dryers Edited by: Processingtalk Editorial Team on 5 April 2005 Renowned freeze-drying experts Usifroid, in collaboration with Air Liquide, the world leade READ MORE
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PennTech dual tray-loader for high output
Votes:40 Comments:0
PennTech dual tray-loader for high output News from: Biopharma Process Systems Edited by: Processingtalk Editorial Team on 9 May 2005 The uniquely designed PennTech trayloaders are now available in READ MORE
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Usifroid acquires loading system expertise
Votes:34 Comments:0
Usifroid acquires loading system expertise News from: Biopharma Process Systems Edited by: Processingtalk Editorial Team on 27 January 2005 Biopharma is pleased to announce that the renowned freeze READ MORE
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Cardinal Health?s Pharmaceutical Technologies & Services Group: Integrating Prop...
Votes:16 Comments:0
Cardinal Health?s Pharmaceutical Technologies & Services Group: Integrating Proprietary Technologies & Expert Services to Accelerate Product Development Not Dated Drug Delivery Technology The drug READ MORE
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Formulation of Hydrophobic Drugs Into Cochleate Delivery Vehicles: A Simplified ...
Votes:29 Comments:0
Formulation of Hydrophobic Drugs Into Cochleate Delivery Vehicles: A Simplified Protocol & Bioral? Formulation Kit By: David Delmarre, PhD; Ruying Lu; Nadine Tatton, PhD; Sara Krause-Elsmore, PhD; S READ MORE
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A Shot at a New Drug-Delivery System
Votes:5 Comments:0
A Shot at a New Drug-Delivery System By: David Pescovitz May 2003 Berkeley Engineering Lab Notes Tomorrow's rural populations may be saved from deadly diseases like malaria, typhoid, and whoopin READ MORE
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Development of Novel Lyophilized Mixed Micelle Amphotericin B Formulation for Tr...
Votes:19 Comments:0
Development of Novel Lyophilized Mixed Micelle Amphotericin B Formulation for Treatment of Systemic Fungal Infection By: Sachin Naik, Mahavir Chougule, Bijay Kumar Padhi and Ambikanandan Misra Curr READ MORE
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Iron Oxide Nanoparticles for Sustained Delivery of Anticancer Agents
Votes:32 Comments:0
Iron Oxide Nanoparticles for Sustained Delivery of Anticancer Agents By: Tapan K. Jain, Marco A. Morales, Sanjeeb K. Sahoo, Diandra L. Leslie-Pelecky, and Vinod Labhasetwar - Department of Pharmace READ MORE
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High-Throughput Purification of Single Compounds and Libraries
Votes:8 Comments:0
High-Throughput Purification of Single Compounds and Libraries By: Mathias Schaffrath, Erich von Roedern,* Peter Hamley, and Hans Ulrich Stilz - Chemistry, Aventis Pharma Deutschland GmbH, a Compan READ MORE
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Particle Size and Temperature Effect on the Physical Stability of PLGA Nanospher...
Votes:21 Comments:0
Particle Size and Temperature Effect on the Physical Stability of PLGA Nanospheres and Microspheres Containing Bodipy By: Sinjan De,1 and Dennis H. Robinson2 - 1Ohio Northern University, College of READ MORE
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Small scale freeze dryer is big on features
Votes:16 Comments:0
Small scale freeze dryer is big on features News from: Biopharma Process Systems Processingtalk Editorial Team on 11 February 2003 This is why the VirTis AdVantage single shelf freeze dryer is so p READ MORE
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Impressive performance from virtual freeze dryer
Votes:11 Comments:0
Impressive performance from virtual freeze dryer News from: Biopharma Process Systems Edited by: Processingtalk Editorial Team on 7 July 2003 The latest addition to the VirTis freeze dryer range is READ MORE
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West Pharmaceutical Services Introduces LyoTec; High Performance Stoppers Meet D...
Votes:5 Comments:0
West Pharmaceutical Services Introduces LyoTec; High Performance Stoppers Meet Demands of New Automated Lyophilization Chamber Technology 3/8/2004 Business Editors/Health/Medical Writers Business READ MORE
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Cardinal Health-Pharmaceutical Development
Votes:38 Comments:0
Cardinal Health-Pharmaceutical Development 8/1/2003 Pharmaceutical Technology Cardinal Health's Zydis technology produces a freeze-dried wafer heralded for its effectiveness for anti-inflammatory READ MORE
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A basic laboratory manual for the small-scale production and testing of I-2 ...
Votes:6 Comments:0
A basic laboratory manual for the small-scale production and testing of I-2 ... Grimes, S.E. FAO Document Repository 13. The production of I-2 Newcastle disease vaccine The seedlot system Prepar READ MORE
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Power law equation and liberation kinetics]
Votes:39 Comments:0
Power law equation and liberation kinetics] 2005 Jan Zatloukal Z. Ceska Slov Farm [Article in Czech] Katedra farmaceuticke technologie Farmaceuticke fakulty Univerzity Karlovy, Hradec Kralove. zs READ MORE
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Collaborative study for the establishment of erythropoietin BRP batch 2.
Votes:14 Comments:0
Collaborative study for the establishment of erythropoietin BRP batch 2. 2004 Dec Behr-Gross ME, Daas A, Bristow AF. Pharmeuropa Bio PubMed European Directorate for the Quality of Medicines, Coun READ MORE
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Exhaled breath condensate pH assays are not influenced by oral ammonia
Votes:9 Comments:0
Exhaled breath condensate pH assays are not influenced by oral ammonia 2005 K Wells1, J Vaughan1, T N Pajewski3, S Hom1, L Ngamtrakulpanit1, A Smith1, A Nguyen1, R Turner2 and J Hunt1 Thorax 1 READ MORE
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Comprehensive metabolite profiling of Sinorhizobium meliloti using gas chromatog...
Votes:3 Comments:0
Comprehensive metabolite profiling of Sinorhizobium meliloti using gas chromatography-mass spectrometry October 2004 Received: 10 March 2004 Revised: 12 May 2004 Accepted: 11 June 2004 Published READ MORE
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Spray-Coating for Biopharmaceutical Powder Formulations: Beyond the Conventional...
Votes:17 Comments:0
Spray-Coating for Biopharmaceutical Powder Formulations: Beyond the Conventional Scale and Its Application March 2004 Yuh-Fun Maa1, 3 , Mahmoud Ameri1, 3, Robert Rigney2, Lendon G. Payne1 and Dex READ MORE
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A small chimerically bifunctional monomeric protein: Tapes japonica lysozyme
Votes:31 Comments:0
A small chimerically bifunctional monomeric protein: Tapes japonica lysozyme September 2003 Received 25 February 2003; received after revision 29 May 2003; accepted 12 June 2003 K. Takeshita1, Y. READ MORE
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Extraction of squalene from yeast by supercritical carbon dioxide
Votes:6 Comments:0
Extraction of squalene from yeast by supercritical carbon dioxide August 2003 P. Bhattacharjee1 and R.S. Singhal1 World Journal of Microbiology and Biotechnology Issue: Volume 19, Number 6 Spr READ MORE
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The relationship between fungal preservation method and secondary metabolite pro...
Votes:39 Comments:0
The relationship between fungal preservation method and secondary metabolite production in Metarhizium anisopliae and Fusarium oxysporum November 2003 M.J. Ryan1 , D. Smith1, P.D. Bridge2, 3 and P READ MORE
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Chitosan/gelatin composite microcarrier for hepatocyte culture
Votes:15 Comments:0
Chitosan/gelatin composite microcarrier for hepatocyte culture June 2004 Keguo Li1, Yun Wang1, Zhenchuan Miao1, Dayong Xu1, Yuefeng Tang1 and Meifu Feng1 Biotechnology Letters Issue: Volume 26, READ MORE
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Stability of the O-octanoyl group of rat ghrelin during chemical synthesis: Coun...
Votes:9 Comments:0
Stability of the O-octanoyl group of rat ghrelin during chemical synthesis: Counter-ion-dependent alteration of an ester bond breakage January 2003 Masanori Ishimaru1, Kumiko Yoshizawa-Kumagaye1, S READ MORE
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A -carrageenan derived oligosaccharide prepared by enzymatic degradation contain...
Votes:23 Comments:0
A -carrageenan derived oligosaccharide prepared by enzymatic degradation containing anti-tumor activity July 2003 Mou Haijin1 , Jiang Xiaolu1 and Guan Huashi1 Journal of Applied Phycology Issue: READ MORE
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Comparative Evaluation of Lyophilized Freeze Dried Platelet Derived Preparation ...
Votes:17 Comments:0
Comparative Evaluation of Lyophilized Freeze Dried Platelet Derived Preparation with Calcium Hydroxide as Pulpotomy Agents in Primary Molars. KALASKAR R Ra, DAMLE S Gb Nair Hospital Dental College READ MORE
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Stop The Bleeding, Now
Votes:12 Comments:0
Stop The Bleeding, Now [Spring 2004] by Angela Spivey Endeavors, UNC-Chapel Hill Three decades of work with freeze-dried platelets could soon help save lives on the battlefield. Frank has been a READ MORE
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Restorative impact of rabeprazole on gastric mucus and mucin production impairme...
Votes:39 Comments:0
Restorative impact of rabeprazole on gastric mucus and mucin production impairment during naproxen administration: its potential clinical significance. 2005 Feb Jaworski T, Sarosiek I, Sostarich S, READ MORE
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Ion-exchange chromatography method for the purification of genomic DNA fraction ...
Votes:15 Comments:0
Ion-exchange chromatography method for the purification of genomic DNA fraction from Mycobacterium bovis Bacillus Calmette-Gu?rin 25 November 2004 Received 13 October 2003; accepted 15 June 2004. READ MORE
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A nosocomial outbreak of Salmonella enteritidis associated with lyophilized ente...
Votes:9 Comments:0
A nosocomial outbreak of Salmonella enteritidis associated with lyophilized enteral nutrition October 2004 Received 25 August 2003; accepted 25 February 2004. Available online 15 September 2004 READ MORE
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Identification of insulin variants using Raman spectroscopy
Votes:23 Comments:0
Identification of insulin variants using Raman spectroscopy 15 September 2004 Received 9 February 2004. Available online 24 July 2004. Corasi Ortiza, Dongmao Zhanga, Yong Xiea, V. Jo Davissonb a READ MORE
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Effect of cefazolin loaded bone matrix gelatin on repairing large segmental bone...
Votes:37 Comments:0
Effect of cefazolin loaded bone matrix gelatin on repairing large segmental bone defects and preventing infection. 2004 Aug You HB, Chen AM. Chin J Traumatol PubMed OBJECTIVE: To explore the poss READ MORE
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Evaluation of a new LightCycler reverse transcriptionpolymerase chain reaction i...
Votes:31 Comments:0
Evaluation of a new LightCycler reverse transcriptionpolymerase chain reaction infectivity assay for detection of human parvovirus B19 in dry-heat inactivation studies June 2005 Grigori G. Prikhod'k READ MORE
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Comparison of ninhydrin method of detecting amine compounds with other methods o...
Votes:26 Comments:0
Comparison of ninhydrin method of detecting amine compounds with other methods of halitosis detection March 2005 K Iwanicka-Grzegorek1, E Lipkowska2, J Kepa1, J Michalik3, M. Wierzbicka1 Oral Disea READ MORE
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Development of a freezing drier for lyophilization of biomaterials
Votes:40 Comments:0
Development of a freezing drier for lyophilization of biomaterials 2004 Jun Wu Z, Gen M, Sun T, Fu X, Xiong D, Qiao Y, Song Y, Sun S, Sheng Z. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. PubMed [Artic READ MORE
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Improvement of the low-temperature stability of an aqueous colloidal ethylcellul...
Votes:26 Comments:0
Improvement of the low-temperature stability of an aqueous colloidal ethylcellulose dispersion, Aquacoat ECD, and preparation/characterization of a redispersible Aquacoat ECD powder By: Wagner K, Bo READ MORE
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Evaluation of different formulation studies on air-filled polymeric microcapsule...
Votes:40 Comments:0
Evaluation of different formulation studies on air-filled polymeric microcapsules by multivariate analysis By: Bjerknes K, Braenden JU, Smistad G, Agerkvist I. - Amersham Health A.S., P.O. Box 4220, READ MORE
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Disposition kinetics of ketotifen from liposomal dry powder for inhalation in ra...
Votes:15 Comments:0
Disposition kinetics of ketotifen from liposomal dry powder for inhalation in rat lung By: Joshi M, Misra A. - Pharmacy Department, Faculty of Technology and Engineering, Kalabhavan, MS University o READ MORE
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Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphen...
Votes:29 Comments:0
Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy By: Konan YN, Cerny R, Favet J, Berton M, Gurny R, Allemann READ MORE
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Influence of beta-cyclodextrin complexation on carbamazepine release from hydrox...
Votes:5 Comments:0
Influence of beta-cyclodextrin complexation on carbamazepine release from hydroxypropyl methylcellulose matrix tablets By: Koester LS, Xavier CR, Mayorga P, Bassani VL. - Programa de Pos-graduacao e READ MORE
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Release of amoxicillin from polyionic complexes of chitosan and poly(acrylic aci...
Votes:18 Comments:0
Release of amoxicillin from polyionic complexes of chitosan and poly(acrylic acid). Study of polymer/polymer and polymer/drug interactions within the network structure By: de la Torre PM, Enobakhare READ MORE
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Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, ...
Votes:32 Comments:0
Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, and dissolution studies By: Reddy MN, Rehana T, Ramakrishna S, Chowdhary KP, Diwan PV. - Pharmacology Division, Indian READ MORE
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The bioequivalence of liquid and freeze-dried formulations of recombinant human ...
Votes:27 Comments:0
The bioequivalence of liquid and freeze-dried formulations of recombinant human chorionic gonadotrophin By: van der Merwe R, Lugan I, Lecuelle H, Papasouliotis O, Buraglio M. - Bourn Hall Clinic, Ca READ MORE
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Mechanism of protein stabilization by sugars during freeze-drying and storage: N...
Votes:21 Comments:0
Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix? By: Chang LL, Shepherd D READ MORE
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Effect of sorbitol and residual moisture on the stability of lyophilized antibod...
Votes:16 Comments:0
Effect of sorbitol and residual moisture on the stability of lyophilized antibodies: Implications for the mechanism of protein stabilization in the solid state By: Chang LL, Shepherd D, Sun J, Tang READ MORE
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Effect of excipients on the stability and aerosol performance of nebulized avisc...
Votes:10 Comments:0
Effect of excipients on the stability and aerosol performance of nebulized aviscumine By: Steckel H, Eskandar F, Witthohn K. - Christian Albrecht University, Kiel, Germany Winter 2003 PubMed Pulm READ MORE
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5-Fluorouracil in topical liposome gels for anticancer treatment--formulation an...
Votes:24 Comments:0
5-Fluorouracil in topical liposome gels for anticancer treatment--formulation and evaluation By: Glavas-Dodov M, Fredro-Kumbaradzi E, Goracinova K, Calis S, Simonoska M, Hincal AA. - Department of P READ MORE
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A method for demonstrating appropriate environmental protection for capping asep...
Votes:37 Comments:0
A method for demonstrating appropriate environmental protection for capping aseptically filled and plugged vials By: Arnold JF, Price JM. - Pfizer Corporation, Portage, Michigan 49002, USA Nov-Dec READ MORE
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Influence of histidine on the stability and physical properties of a fully human...
Votes:13 Comments:0
Influence of histidine on the stability and physical properties of a fully human antibody in aqueous and solid forms By: Chen B, Bautista R, Yu K, Zapata GA, Mulkerrin MG, Chamow SM. - Department of READ MORE
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Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falc...
Votes:8 Comments:0
Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum By: Feng XP, Liu DQ. - Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention, WHO READ MORE
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Preparation and characterization of novel coenzyme Q10 nanoparticles engineered ...
Votes:22 Comments:0
Preparation and characterization of novel coenzyme Q10 nanoparticles engineered from microemulsion precursors By: Hsu CH, Cui Z, Mumper RJ, Jay M. - Division of Pharmaceutical Sciences, College of P READ MORE
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Molecular mobility of lyophilized poly(vinylpyrrolidone) and methylcellulose as ...
Votes:35 Comments:0
Molecular mobility of lyophilized poly(vinylpyrrolidone) and methylcellulose as determined by the laboratory and rotating frame spin-lattice relaxation times of 1H and 13C By: Yoshioka S, Aso Y, Koj READ MORE
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A simple and reliable semipreparative high-performance liquid chromatography tec...
Votes:4 Comments:0
A simple and reliable semipreparative high-performance liquid chromatography technique for the isolation of marker-grade hyperforin from Hypericum perforatum L extract By: Anand R, Puri SC, Verma N, READ MORE
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Effective encapsulation of proteins into size-controlled phospholipid vesicles u...
Votes:18 Comments:0
Effective encapsulation of proteins into size-controlled phospholipid vesicles using freeze-thawing and extrusion By: Sou K, Naito Y, Endo T, Takeoka S, Tsuchida E. - Advanced Research Institute for READ MORE
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Lupus anticoagulant (LA) testing: performance of clinical laboratories assessed ...
Votes:31 Comments:0
Lupus anticoagulant (LA) testing: performance of clinical laboratories assessed by a national survey using lyophilized affinity-purified immunoglobulin with LA activity By: Tripodi A, Biasiolo A, Ch READ MORE
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Stem Cells, Fat Tissue as Routes to Cell-Based Therapy
Votes:40 Comments:0
Stem Cells, Fat Tissue as Routes to Cell-Based Therapy 1 June 2005 Neil Canavan Drug Discovery & Development Despite cost and regulatory hurdles, inroads from the bench, the desk, and even the gre READ MORE
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Will potatoes help prevent hepatitis E?
Votes:15 Comments:0
Will potatoes help prevent hepatitis E? May 31, 2005 By Anna Groner Checkbiotech ITHACA / TOKYO / TEMPE - Researchers in the U.S. and Japan are trying to develop an oral vaccine to prevent hepat READ MORE
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Automated loading and unloading systems for lyophilizers: autoloader systems can...
Votes:21 Comments:0
Automated loading and unloading systems for lyophilizers: autoloader systems can greatly reduce the risk of product contamination and are a cost-effective choice for many applications February 2004 READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_2_28/ai_113416742

PROTEIN SPRAY-FREEZE-DRYING: THE NEGATIVE INFLUENCE OF AMORPHOUS MANNITOL ON PRO...
Votes:16 Comments:0
PROTEIN SPRAY-FREEZE-DRYING: THE NEGATIVE INFLUENCE OF AMORPHOUS MANNITOL ON PROTEIN STABILITY Spring 2005 C. Rochelle1, G. Lee1, P. Laidler2, R. Prasad2, PH.D Thesis 1 Department of Pharmaceutics, READ MORE
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Eudragit S100 Entrapped Insulin Microspheres for Oral Delivery
Votes:10 Comments:0
Eudragit S100 Entrapped Insulin Microspheres for Oral Delivery January 21, 2005 Deepti Jain1, A.K.Panda2 and D.K. Majumdar1 1Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences READ MORE
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Profiling analysis of oligosaccharides in antibody pharmaceuticals by capillary ...
Votes:24 Comments:0
Profiling analysis of oligosaccharides in antibody pharmaceuticals by capillary electrophoresis October 2004 Satoru Kamodaa, b, Chie Nomuraa, Mitsuhiro Kinoshitaa, Saori Nishiurac, Rika Ishikawab, K READ MORE
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A comparative study of the potential of solid triglyceride nanostructures coated...
Votes:19 Comments:0
A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery May 2005 M. Garcia-Fuentes, C. Prego, READ MORE
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Distribution of liposome-encapsulated antimony in dogs
Votes:13 Comments:0
Distribution of liposome-encapsulated antimony in dogs February 2003 D.A. Schettini1, A.P. Costa Val3, L.F. Souza2, C. Demicheli4, O.G.F. Rocha5, M.N. Melo2, M.S.M. Michalick2 and F. Fr?zard1 Depar READ MORE
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Superporous Hydrogels for Pharmaceutical & Other Applications
Votes:7 Comments:0
Superporous Hydrogels for Pharmaceutical & Other Applications Kinam Park, PhD, Akina, Inc. Drug Delivery Technology Please visit the web site to view the article in its entirety. INTRODUCTION For READ MORE
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A novel freeze pelletization technique for preparing matrix pellets: a novel and...
Votes:35 Comments:0
A novel freeze pelletization technique for preparing matrix pellets: a novel and simple freeze-pelletization technique generates immediate- or sustained-release spherical pellets with a narrow particl READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_10_28/ai_n6361864

Practical experiences in the transfer and scale-up of freeze-dried products: sev...
Votes:11 Comments:0
Practical experiences in the transfer and scale-up of freeze-dried products: several key steps should be taken to ensure a successful transfer of a freeze-dried product from a client to a contract man READ MORE
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Partial structure of the phylloxin gene from the giant monkey frog, Phyllomedusa...
Votes:24 Comments:0
Partial structure of the phylloxin gene from the giant monkey frog, Phyllomedusa bicolor: Parallel cloning of precursor cDNA and genomic DNA from lyophilized skin secretion. Chen T, Gagliardo R, Walk READ MORE
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Mechanisms of Inactivation of HSV-2 during Storage in Frozen and Lyophilized For...
Votes:19 Comments:0
Mechanisms of Inactivation of HSV-2 during Storage in Frozen and Lyophilized Forms April 8, 2005 Raino K. Hansen, Suling Zhai, Jeremy N. Skepper, Mike D. Johnston, H. Oya Alpar, and Nigel K. H. Slat READ MORE
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Nonconventional hydrolytic dehalogenation of 1-chlorobutane by dehydrated bacter...
Votes:13 Comments:0
Nonconventional hydrolytic dehalogenation of 1-chlorobutane by dehydrated bacteria in a continuous solid-gas biofilter May 31, 2005 Benjamin Erable, Isabelle Goubet, Sylvain Lamare, Amira Seltana, M READ MORE
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Degradation of a lyophilized formulation of BMS-204352: identification of degrad...
Votes:27 Comments:0
Degradation of a lyophilized formulation of BMS-204352: identification of degradants and role of elastomeric closures. 2005 Nassar MN, Nesarikar VV, Lozano R, Huang Y, Palaniswamy V., Biopharmaceuti READ MORE
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Optimisation of a freeze-drying process of high purity Factor VIII and Factor IX...
Votes:22 Comments:0
Optimisation of a freeze-drying process of high purity Factor VIII and Factor IX concentrates October 2003 By Elena Ronzi, Antonio Capolongo, Giorgio Rovero, Enzo Bucci, Sara Mondini and Anna Falb READ MORE
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Clinical results of OK-432 injection therapy for ganglions.
Votes:35 Comments:0
Clinical results of OK-432 injection therapy for ganglions. April 2005 Taniguchi T, Motomura H, Ohba N, Harada T, Muraoka M, Ishii M., Department of Plastic and Reconstructive Surgery, Osaka City Un READ MORE
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Carboxymethyl high amylose starch (CM-HAS) as excipient for Escherichia coli ora...
Votes:30 Comments:0
Carboxymethyl high amylose starch (CM-HAS) as excipient for Escherichia coli oral formulations. May 2005 Calinescu C, Mulhbacher J, Nadeau E, Fairbrother JM, Mateescu MA., Department of Chemistry an READ MORE
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Development of an enteric-coated formulation containing freeze-dried, viable rec...
Votes:6 Comments:0
Development of an enteric-coated formulation containing freeze-dried, viable recombinant Lactococcus lactis for the ileal mucosal delivery of human interleukin-10. May 28, 2005 Huyghebaert N, Vermei READ MORE
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Practical formulation and process development of freeze-dried products.
Votes:38 Comments:0
Practical formulation and process development of freeze-dried products. 2005 Schwegman JJ, Hardwick LM, Akers MJ., Baxter BioPharma Solutions, Bloomington, IN, USA. Pharm Dev Technol. 2005;10(2):15 READ MORE
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Determination of the binding constant between alprostadil and alpha-cyclodextrin...
Votes:14 Comments:0
Determination of the binding constant between alprostadil and alpha-cyclodextrin by capillary electrophoresis: Implications for a freeze-dried formulation May 26, 2005 Benjamin R. Schipper 1, Tore R READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110503230/ABSTRACT

Antifungal effect and possible mode of activity of a compound from the marine sp...
Votes:9 Comments:0
Antifungal effect and possible mode of activity of a compound from the marine sponge Dysidea herbacea. June 2005 Sionov E, Roth D, Sandovsky-Losica H, Kashman Y, Rudi A, Chill L, Berdicevsky I, Sega READ MORE
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Bioequivalence of liquid and freeze-dried recombinant human follicle-stimulating...
Votes:22 Comments:0
Bioequivalence of liquid and freeze-dried recombinant human follicle-stimulating hormone January 2005 Lugan I.1; Febbraro S.2; Lecuelle H.1; Papasouliotis O.1; Ho-Nguyen Q.1; Buraglio M.1 1: Seron READ MORE
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Thermoanalytical Techniques for the Investigation of the Freeze Drying Process a...
Votes:36 Comments:0
Thermoanalytical Techniques for the Investigation of the Freeze Drying Process and Freeze-Dried Products June 2005 Kett, Vicky; McMahon, Debra; Ward, Kevin - School of Pharmacy, Queen's University READ MORE
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The effect of freeze-drying with different cryoprotectants and gamma-irradiation...
Votes:11 Comments:0
The effect of freeze-drying with different cryoprotectants and gamma-irradiation sterilization on the characteristics of ciprofloxacin HCl-loaded poly(D,L-lactide-glycolide) nanoparticles June 2005 READ MORE
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SepPhase Behavior of Amorphous Molecular Dispersions I: Determination of the Deg...
Votes:6 Comments:0
Phase Behavior of Amorphous Molecular Dispersions I: Determination of the Degree and Mechanism of Solid Solubility September 2004 Madhav Vasanthavada1; Wei-Qin Tong2; Yatindra Joshi2; M. Serpil Kisl READ MORE
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Peptide-mediated Gene Transfer of Cationic Lipid/Plasmid DNA Complexes to Endoth...
Votes:38 Comments:0
Peptide-mediated Gene Transfer of Cationic Lipid/Plasmid DNA Complexes to Endothelial Cells May 2004 K. Anwer1; G. Kao2; A. Rolland3; W.H.P. Driessen4; S.M. Sullivan4 1: Expression Genetics Huntsv READ MORE
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Surface-Modified Mesoporous Ceramics as Delivery Vehicle for Haemoglobin
Votes:14 Comments:0
Surface-Modified Mesoporous Ceramics as Delivery Vehicle for Haemoglobin May-June 2004 Patil S.; Pancholi S.S.; Agrawal S.; Agrawal G.P.; 1: Department of Pharmaceutical Sciences, Dr. H. S. Gour Un READ MORE
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Skin tests with native, depigmented and glutaraldehyde polymerized allergen extr...
Votes:9 Comments:0
Skin tests with native, depigmented and glutaraldehyde polymerized allergen extracts. 2005 Casanovas M, Gomez MJ, Carnes J, Fernandez-Caldas E., Laboratorios LETI, Tres Cantos, Madrid, Spain. J Inv READ MORE
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A method to determine the incorporation capacity of camptothecin in liposomes.
Votes:22 Comments:0
A method to determine the incorporation capacity of camptothecin in liposomes. June 2004 Saetern AM, Flaten GE, Brandl M., University of Tromso, Institute of Pharmacy, Department of Pharmaceutics an READ MORE
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Effects of lyophilization on the infectivity of enveloped and non-enveloped viru...
Votes:36 Comments:0
Effects of lyophilization on the infectivity of enveloped and non-enveloped viruses in bone tissue Received 25 February 2005; accepted 15 April 2005. Available online 6 June 2005. Christine Uhle READ MORE
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Preparation of cells cultured on silicon wafers for mass spectrometry analysis
Votes:11 Comments:0
Preparation of cells cultured on silicon wafers for mass spectrometry analysis Published Online: 6 Jun 2005 Received: 25 August 2004; Accepted: 2 February 2005 Andrea Wittig 1 *, Martin Wiemann 2, READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110520580/ABSTRACT

Morphology research of the rat sciatic nerve bridged by collage-heparin sulfate ...
Votes:6 Comments:0
Morphology research of the rat sciatic nerve bridged by collage-heparin sulfate scaffold. 2005 Apr 22 Wang SS, Hu YY, Luo ZJ, Chen LW, Liu HL, Meng GL, Lu R, Xu XZ. Zhonghua Wai Ke Za Zhi. PubMed READ MORE
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A study of the impact of freezing on the lyophilization of a concentrated formul...
Votes:39 Comments:0
A study of the impact of freezing on the lyophilization of a concentrated formulation with a high fill depth. 2005 Liu J, Viverette T, Virgin M, Anderson M, Paresh D. Pharm Dev Technol.. PubMed D READ MORE
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Nitric oxide does not cause extravasation in endotoxemic rats.
Votes:33 Comments:0
Nitric oxide does not cause extravasation in endotoxemic rats. 2005 May Metcalf K, Berg A, Ericson AC, Lisander B. J Trauma. PubMed Department of Medicine and Care, Division of Anaesthesiology an READ MORE
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Effect of freeze-drying and gamma irradiation on biomechanical properties of bov...
Votes:28 Comments:0
Effect of freeze-drying and gamma irradiation on biomechanical properties of bovine pericardium June 2005 Received: 14 January 2004 Accepted: 05 August 2004 Y.M. Hafeez1, A.B.Z. Zuki2 , N. Yuso READ MORE
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Impact of carbon and nitrogen nutrition on the quality, yield and composition of...
Votes:23 Comments:0
Impact of carbon and nitrogen nutrition on the quality, yield and composition of blastospores of the bioinsecticidal fungus Paecilomyces fumosoroseus May 2005 Received: 9 December 2002 Accepted: 1 READ MORE
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Nonphospholipid Vesicles of Carboplatin for Lung Targeting
Votes:17 Comments:0
Nonphospholipid Vesicles of Carboplatin for Lung Targeting Apr-Jun 2003 B. Lu A1, J. Q. Zhang A1, H. Yang A1 Drug Delivery Taylor & Francis A1 West China School of Pharmacy, Sichuan Universit READ MORE
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Physicochemical Characterization of Influenza Viral Vaccine Loaded Surfactant Ve...
Votes:31 Comments:0
Physicochemical Characterization of Influenza Viral Vaccine Loaded Surfactant Vesicles Apr-Jun 2003 S. C. Chattaraj A1 and S. K. Das A2 Drug Delivery Taylor & Francis A1 Mylan Pharmaceuticals READ MORE
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Chitosan-DNA Nanoparticles: Effect on DNA Integrity, Bacterial Transformation an...
Votes:6 Comments:0
Chitosan-DNA Nanoparticles: Effect on DNA Integrity, Bacterial Transformation and Transfection Efficiency June 2004 Asuman Bozkir and Ongun Mehmet Saka Journal of Drug Targeting Taylor & Franci READ MORE
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Optimization of the Freeze-Drying Cycle: A New Model for Pressure Rise Analysis
Votes:39 Comments:0
Optimization of the Freeze-Drying Cycle: A New Model for Pressure Rise Analysis Number 7 / 2004 P. Chouvenc A1 A2, S. Vessot A1, J. Andrieu A1, P. Vacus A2 Drying Technology Taylor & Francis READ MORE
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Melting Behavior and Morphology of Freeze-Dried Ultra-high Molar Mass Polyethyle...
Votes:15 Comments:0
Melting Behavior and Morphology of Freeze-Dried Ultra-high Molar Mass Polyethylene Number 1 / 2003 Zhongyong Fan A1, Yiren Wang A1, Na Ni A1, Haishan Bu A1 Journal of Macromolecular Science, Part READ MORE
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A Direct Characterization Method of the Ice Morphology. Relationship Between Mea...
Votes:28 Comments:0
A Direct Characterization Method of the Ice Morphology. Relationship Between Mean Crystals Size and Primary Drying Times of Freeze-Drying Processes 2004 Aur?lie Hottot A1, S?verine Vessot A1, Julie READ MORE
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Optimal Control of the Secondary Drying Stage of Freeze Drying of Solutions in V...
Votes:23 Comments:0
Optimal Control of the Secondary Drying Stage of Freeze Drying of Solutions in Vials Using Variational Calculus 2005 Hasan Sadikoglu A1 Drying Technology Taylor & Francis A1 Department of Ene READ MORE
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Valproic Acid-Hydrophilic Cyclodextrin Complexes and Valproic Acid-Solid Dispers...
Votes:37 Comments:0
Valproic Acid-Hydrophilic Cyclodextrin Complexes and Valproic Acid-Solid Dispersions: Evaluation of Their Potential Pharmaceutical Use 2004 G. Trapani A1, A. Cutrignelli A1, A. Latrofa A1, M. Franco READ MORE
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Solid-state photodegradation of bovine somatotropin (bovine growth hormone): Evi...
Votes:31 Comments:0
Solid-state photodegradation of bovine somatotropin (bovine growth hormone): Evidence for tryptophan-mediated photooxidation of disulfide bonds Published Online: 28 May 2003 Received: 12 December 20 READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/104535430/ABSTRACT

Antidiabetic effect of diasulin, a herbal drug, on blood glucose, plasma insulin...
Votes:26 Comments:0
Antidiabetic effect of diasulin, a herbal drug, on blood glucose, plasma insulin and hepatic enzymes of glucose metabolism in hyperglycaemic rats July 2004 L. Pari and R. Saravanan, Department of Bi READ MORE
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1462-8902.2004.0349...

Screening for antihyperglycaemic activity in several local herbs of Malaysia
Votes:40 Comments:0
Screening for antihyperglycaemic activity in several local herbs of Malaysia December 2004 Rafidah Husen, Azimahtol Hawariah Lope Pihie and Meenakshii Nallappan, School of Bioscience and Biotechnolo READ MORE
http://www.sciencedirect.com/science...

Thermogelling Poly(caprolactone-b-ethylene glycol-b-caprolactone) Aqueous Soluti...
Votes:34 Comments:0
Thermogelling Poly(caprolactone-b-ethylene glycol-b-caprolactone) Aqueous Solutions May 2005 Soo Jin Bae, Ju Myung Suh, Youn Soo Sohn, You Han Bae, Sung Wan Kim, and Byeongmoon Jeong* Department of READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/mamobx/2005/38/i12/abs/ma0504...

Growth hormone therapy.
Votes:29 Comments:0
Growth hormone therapy. February 2005 Bajpai Anurag1, Menon P SN2 1 Division of Pediatric Endocrinology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India 2 Depar READ MORE
http://www.ijppediatricsindia.org/article.asp...

A Double-blind Treatment Study of Bacterial Vaginosis with Normal Vaginal Lactob...
Votes:23 Comments:0
A Double-blind Treatment Study of Bacterial Vaginosis with Normal Vaginal Lactobacilli after an Open Treatment with Vaginal Clindamycin Ovules January 2005 Katarina Eriksson , Bodil Carlsson , Urban READ MORE
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Development of 99mTc-neomannosyl human serum albumin (99mTc-MSA) as a novel rece...
Votes:37 Comments:0
Development of 99mTc-neomannosyl human serum albumin (99mTc-MSA) as a novel receptor binding agent for sentinel lymph node imaging. Jeong, Jae Min; Hong, Mee Kyung; Kim, Young Joo; Lee, Jaetae; Kang READ MORE
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Collaborative study to establish the Low-molecular-mass heparin for assay--Europ...
Votes:31 Comments:0
Collaborative study to establish the Low-molecular-mass heparin for assay--European Pharmacopoeia Biological Reference Preparation. December 2004 Gray E, Rigsby P, Behr-Gross ME., National Institute READ MORE
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Protective effect of fermented red ginseng on a transient focal ischemic rats.
Votes:7 Comments:0
Protective effect of fermented red ginseng on a transient focal ischemic rats. November 2004 Bae EA, Hyun YJ, Choo MK, Oh JK, Ryu JH, Kim DH., College of Pharmacy and Kyung Hee University, 1, Hoegi, READ MORE
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Pharmacological study of Stachytarpheta cayennensis Vahl in rodents.
Votes:40 Comments:0
Pharmacological study of Stachytarpheta cayennensis Vahl in rodents. November 2004 Mesia-Vela S, Souccar C, Lima-Landman MT, Lapa AJ.; Department of Pharmacology, Natural Products Section, Escola P READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antibacterial effect of borage (Echium amoenum) on Staphylococcus aureus
Votes:15 Comments:0
Antibacterial effect of borage (Echium amoenum) on Staphylococcus aureus October 2004 Mohsen Abolhassani, Department of Immunology, Pasteur Institute of Iran, Tehran 13164, Iran Brazilian Journal READ MORE
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Lyophilization By Vetter: Make The Most Of Your Sensitive Drugs
Votes:10 Comments:0
Lyophilization By Vetter: Make The Most Of Your Sensitive Drugs 05/11/2005 Published By: Vetter Pharma-Fertigung GmbH & Co. KG As a global leader in the production of aseptically pre-filled appl READ MORE
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Lonza aims to get bigger in peptides
Votes:5 Comments:0
Lonza aims to get bigger in peptides 02/05/2005 NOVIS Lonza is planning a major exansion of its peptides manufacturing capacities at Visp, Switzerland, in response to what it said was ?the increase READ MORE
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Dutch scheme extends helping hand to biotech SMEs
Votes:18 Comments:0
Dutch scheme extends helping hand to biotech SMEs 02/03/2005 NOVIS The Netherlands has set up a programme to boost its biotechnology sector by helping small and medium-sized biopharma firms to de READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Niro extends drying test centre for pharma
Votes:13 Comments:0
Niro extends drying test centre for pharma 02/03/2005 NOVIS Denmark-headquartered Niro is finalizing a ?10 million investment programme centred on the expansion of its drying test site, located at READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Pfizer undertakes ?240m expansion at Irish plant
Votes:26 Comments:0
Pfizer undertakes ?240m expansion at Irish plant 16/09/2004 NOVIS Rumours of the demise of Ireland as a hotbed of pharmaceutical manufacturing may be premature. Pfizer has just unveiled a plan to s READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Liqiud formulation of the postharvest biocontrol agent Candida sake CPA-1 in iso...
Votes:21 Comments:0
Liqiud formulation of the postharvest biocontrol agent Candida sake CPA-1 in isotonic solutions Apr 2003 by Abadias, Maribel, Usall, Josep, Teixido, Neus, Vinas, Immaculada Phytopathology ABS READ MORE
http://www.findarticles.com/p/articles/mi_qa4061/is_200304/ai_n9185355

Advanced Stage Palliative Prostate Cancer Treatment to Be Offered with West Phar...
Votes:16 Comments:0
Advanced Stage Palliative Prostate Cancer Treatment to Be Offered with West Pharmaceutical Services' Clip'n'Ject? Reconstitution System April 11, 2005 PR Newswire LIONVILLE, Pa., April 11 /PRNews READ MORE
http://www.findarticles.com/p/articles/mi_m4PRN/is_2005_April_11/ai_n1...

Particle design
Votes:29 Comments:0
Particle design Jan, 2005 Pharmaceutical Technology Hovione offers a brochure that describes its particle design technology and CGMP-compliant spray drying facilities, which have been designed to READ MORE
http://www.findarticles.com/p/articles/mi_m0EEH/is_1_29/ai_n9485009

Shell Bath offers safe way to pre-freeze multiple flasks
Votes:24 Comments:0
Shell Bath offers safe way to pre-freeze multiple flasks Dec 13, 2004 Product News Network Self-contained VirTis Benchtop Shell Bath produces frozen product coating to inside of freeze-drying fla READ MORE
http://www.findarticles.com/p/articles/mi_m0PIL/is_2004_Dec_13/ai_n856...

Properties of nanostructured hydroxyapatite prepared by a spray drying technique
Votes:19 Comments:0
Properties of nanostructured hydroxyapatite prepared by a spray drying technique Nov-Dec, 2004 by Laurence C. Chow, Limin Sun, Bernard Hockey Journal of Research of the National Institute of Sta READ MORE
http://www.findarticles.com/p/articles/mi_m0IKZ/is_6_109/ai_n13603808

Freeze-drying firm warms to Maryland's biotech zone
Votes:13 Comments:0
Freeze-drying firm warms to Maryland's biotech zone May 20, 2005 Neil Adler American City Business Journals, Inc. After scouting space throughout the mid-Atlantic region, Israel-based Core Dynam READ MORE
http://washington.bizjournals.com/washington/stories/2005/05/23/story7...

Safer, More Stable Products
Votes:27 Comments:0
Safer, More Stable Products November 01, 2004 Thomas W. Patapoff and David E. Overcashier BioPharm International The freezing method used during lyophilization can substantially affect the structu READ MORE
http://www.biopharminternational.com/biopharm/article/articleDetail.js...

Particle & Device Engineering for Inhalation Drug Delivery
Votes:3 Comments:0
Particle & Device Engineering for Inhalation Drug Delivery March 2004 Kavitha Koushik and Uday B. Kompella Drug Delivery Technology The inhalation route, employed primarily for drugs acting in th READ MORE
http://www.pharmainfo.net/displayarticle2994.html

Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization
Votes:35 Comments:0
Cyclodextrin Complexes of Celecoxib: Molecular-Modeling, Characterization March 5, 2004 M. Narender Reddy, Tasneem Rehana, S. Ramakrishna, K.P.R. Chowdary, Prakash V. Diwan AAPS PharmSci Celecoxib READ MORE
http://www.pharmainfo.net/displayarticle2660.html

Novel inhaler devices: balancing innovation against price is important
Votes:11 Comments:0
Novel inhaler devices: balancing innovation against price is important 26 February 2005 Jenny Bryan The Pharmaceutical Journal If you are designing a new inhaler for lung disease, do you put you READ MORE
http://www.pjonline.com/editorial/20050226/articles/p241inhalerdevices...

Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by...
Votes:5 Comments:0
Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis May 2005 K.L. Yap, X. Liu, J.C. Thenmoz READ MORE
http://www.sciencedirect.com/science...

Pegylated nanoparticles based on poly(methyl vinyl ether-co-maleic anhydride): p...
Votes:19 Comments:0
Pegylated nanoparticles based on poly(methyl vinyl ether-co-maleic anhydride): preparation and evaluation of their bioadhesive properties April 2005 Krassimira Yonchevaa, 1, Elena Lizarragab and Jua READ MORE
http://www.sciencedirect.com/science...

Multicomponent complex formation between vinpocetine, cyclodextrins, tartaric ac...
Votes:33 Comments:0
Multicomponent complex formation between vinpocetine, cyclodextrins, tartaric acid and water-soluble polymers monitored by NMR and solubility studies January 2005 Laura Ribeiroa, Rui A. Carvalhob, READ MORE
http://www.sciencedirect.com/science...

Preparation of budesonide? and indomethacin?hydroxypropyl-?-cyclodextrin (HPBCD)...
Votes:3 Comments:0
Preparation of budesonide? and indomethacin?hydroxypropyl-?-cyclodextrin (HPBCD) complexes using a single-step, organic-solvent-free supercritical fluid process October 2004 Nagesh Bandia, 1, Willia READ MORE
http://www.sciencedirect.com/science...

Comparative therapeutic efficacy of a novel lyophilized amphotericin B lecithin-...
Votes:16 Comments:0
Comparative therapeutic efficacy of a novel lyophilized amphotericin B lecithin-based oil?water microemulsion and deoxycholate-amphotericin B in immunocompetent and neutropenic mice infected with Cand READ MORE
http://www.sciencedirect.com/science...

Bupivacaine containing dry emulsion can prolong epidural anesthetic effects in r...
Votes:11 Comments:0
Bupivacaine containing dry emulsion can prolong epidural anesthetic effects in rabbits May 2004 G. Dollo, , P. Le Corre, F. Chevanne and R. Le Verge European Journal of Pharmaceutical Sciences A READ MORE
http://www.sciencedirect.com/science...

Enrichment of hyperforin from St. John?s Wort (Hypericum perforatum) by pilot-sc...
Votes:6 Comments:0
Enrichment of hyperforin from St. John?s Wort (Hypericum perforatum) by pilot-scale supercritical carbon dioxide extraction March 2004 Harald R?mpp a, Christoph Seger b, c, Claudia S. Kaiser a, Erns READ MORE
http://www.sciencedirect.com/science...

Characterization of supercritical fluid extracts of St. John?s Wort (Hypericum p...
Votes:38 Comments:0
Characterization of supercritical fluid extracts of St. John?s Wort (Hypericum perforatum L.) by HPLC?MS and GC?MS March 2004 Christoph Seger , , a, c, Harald R?mpp b, Sonja Sturm a, Ernst Haslinge READ MORE
http://www.sciencedirect.com/science...

Delivery of liposomes in dry powder form: aerodynamic dispersion properties
Votes:14 Comments:0
Delivery of liposomes in dry powder form: aerodynamic dispersion properties December 2003 Tejas R. Desaia, Robert E. W. Hancockb and Warren H. Finlay European Journal of Pharmaceutical Sciences A READ MORE
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Formulation and characterization of DNA?polyethylenimine?dextran sulfate nanopar...
Votes:9 Comments:0
Formulation and characterization of DNA?polyethylenimine?dextran sulfate nanoparticles July 2003 Waree Tiyaboonchaia, James Woiszwillob and C. Russell Middaugh European Journal of Pharmaceutical S READ MORE
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Role of a non-natural -C-nucleotide unit in DNA as a template for DNA and RNA sy...
Votes:3 Comments:0
Role of a non-natural -C-nucleotide unit in DNA as a template for DNA and RNA syntheses and as a substrate for nucleolytic digestion September 2003 Saeko Aketania, Kentaro Tanakaa, Kaneyoshi Yamamot READ MORE
http://www.sciencedirect.com/science...

Spray-dried redispersible oil-in-water emulsion to improve oral bioavailability ...
Votes:17 Comments:0
Spray-dried redispersible oil-in-water emulsion to improve oral bioavailability of poorly soluble drugs July 2003 Gilles Dollo, , a, Pascal Le Correa, Alexis Gu?rina, Fran?ois Chevannea, Jean Louis READ MORE
http://www.sciencedirect.com/science...

Preparation of ?-PGA/chitosan composite tissue engineering matrices
Votes:30 Comments:0
Preparation of ?-PGA/chitosan composite tissue engineering matrices October 2005 Chien-Yang Hsieha, Sung-Pei Tsaia, Da-Ming Wanga, Yaw-Nan Changb and Hsyue-Jen Hsieh Biomaterials Abstract ?-poly READ MORE
http://www.sciencedirect.com/science...

Size-controlled hydroxyapatite nanoparticles as self-organized organic?inorganic...
Votes:6 Comments:0
Size-controlled hydroxyapatite nanoparticles as self-organized organic?inorganic composite materials September 2005 Viorel Marin Rusua, b, , , , Chuen-How Nga, Max Wilkec, Brigitte Tierscha, Peter READ MORE
http://www.sciencedirect.com/science...

Crystallization, Characterization and Crystal Structure of Host-Guest Inclusion ...
Votes:28 Comments:0
Crystallization, Characterization and Crystal Structure of Host-Guest Inclusion Complexes. Potential Application for Enantiomeric Resolution 2003 A. Grandeury a, S. Tissea, S. Petit a, G. Gouhier b, READ MORE
http://www.eurostar-science.org/conferences/abstrsph7/petit1.pdf

Drug Resistance Pattern of Mycobacterium Tuberculosis in Seropositive and Serone...
Votes:22 Comments:0
Drug Resistance Pattern of Mycobacterium Tuberculosis in Seropositive and Seronegative HIV-TB Patients in Pune, India 20 May 2005 Red Nova Background & objectives: Tuberculosis is the commonest opp READ MORE
http://www.rednova.com/news/health/150890/drug_resistance_pattern_of_m...

SARS vaccine offers food for thought
Votes:36 Comments:0
SARS vaccine offers food for thought June 13, 2005 Canadian Press Hold the pickles, hold the lettuce, but if you want immune protection against SARS, don't hold the tomato. American researchers h READ MORE
http://www.theglobeandmail.com/servlet/story/RTGAM.20050613.wsars0613/...

Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying...
Votes:17 Comments:0
Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying: effect of protective agents (polyethyleneimine and sugars) on the stability of DNA January 2004 Jung-hua Steven Kuo READ MORE
http://thesius.ingentaconnect.com/vl=7963416/cl=17/tt=1472/ini=rpsgb/n...

Oil-based formulations for oral delivery of insulin
Votes:12 Comments:0
Oil-based formulations for oral delivery of insulin September 2004 Chun-Lei Li ; Ying-Jie Deng Journal of Pharmacy and Pharmacology DOI: 10.1211/0022357044175 Publisher: Pharmaceutical Press READ MORE
http://thesius.ingentaconnect.com/vl=7963416/cl=17/tt=1472/ini=rpsgb/n...

Comparison of post-emulsification freeze drying or spray drying processes for th...
Votes:26 Comments:0
Comparison of post-emulsification freeze drying or spray drying processes for the microencapsulation of plasmid DNA July 2005 Majella E. Lane ; Fiona S. Brennan ; Owen I. Corrigan Journal of Phar READ MORE
http://thesius.ingentaconnect.com/vl=7963416/cl=17/tt=1472/ini=rpsgb/n...

The Evolution of Parenteral Drug Packaging
Votes:29 Comments:0
The Evolution of Parenteral Drug Packaging March 2004 Jenevieve Blair Polin PMPN Newer configurations and materials expand the options for packaging parenteral products. Prefilled syringes are a READ MORE
http://www.devicelink.com/pmpn/archive/04/03/001.html

Effect of aging on the physical properties of amorphous trehalose.
Votes:37 Comments:0
Effect of aging on the physical properties of amorphous trehalose. May 2004 Surana R, Pyne A, Suryanarayanan R., Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota 55455, U READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Standardisation and physicochemical characterisation of the extracts of seeds of...
Votes:31 Comments:0
Standardisation and physicochemical characterisation of the extracts of seeds of Glinus lotoides. January 2004 Endale A, Schmidt PC, Gebre-Mariam T., Department of Pharmaceutics, School of Pharmacy, READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Growth-inhibitory Effects of the Red Alga Gelidium amansii on Cultured Cells
Votes:26 Comments:0
Growth-inhibitory Effects of the Red Alga Gelidium amansii on Cultured Cells February 2004 Yue-Hwa Chen, Ching-Jung Tu1 and Hsiao-Ting Wu, School of Nutrition and Health Sciences, Taipei Medical Un READ MORE
http://www.jstage.jst.go.jp/article/bpb/27/2/27_180/_article/-char/en

Protection of Protein Secondary Structure by Saccharides of Different Molecular ...
Votes:21 Comments:0
Protection of Protein Secondary Structure by Saccharides of Different Molecular Weights during Freeze-Drying February 2004 Izutsu K, Aoyagi N, Kojima S., National Institute of Health Sciences, Tokyo READ MORE
http://www.jstage.jst.go.jp/article/cpb/52/2/52_199/_article/-char/en

Fabrication and in vitro testing of polymeric delivery system for condensed DNA.
Votes:34 Comments:0
Fabrication and in vitro testing of polymeric delivery system for condensed DNA. December 2003 Huang YC, Connell M, Park Y, Mooney DJ, Rice KG., College of Pharmacy, University of Michigan, Ann Arbo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var....
Votes:29 Comments:0
Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis. July-September 2003 Shimpo K, Chihara T, Beppu H, Ida C, Kaneko T, Hoshino M, Kuzuya H., Fujita Memorial READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Formulation of a liquid ovine Fab-based antivenom for the treatment of envenomat...
Votes:4 Comments:0
Formulation of a liquid ovine Fab-based antivenom for the treatment of envenomation by the Nigerian carpet viper (Echis ocellatus) September 2003 Al-Abdulla I, Garnvwa JM, Rawat S, Smith DS, Landon READ MORE
http://www.sciencedirect.com/science...

Crystalline Polymorphism, Habits, Agglomeration States and Amorphous Phases : An...
Votes:18 Comments:0
Crystalline Polymorphism, Habits, Agglomeration States and Amorphous Phases : An Overview of the Importance of the Solid State in Pharmaceutical Development 2003 eurostar-science by Dr Michel BAUER READ MORE
http://www.eurostar-science.org/conferences/abstrsph7/bauer.pdf

Helium leak test for sterility assurance of a sealed bag. II: Establishing a tes...
Votes:13 Comments:0
Helium leak test for sterility assurance of a sealed bag. II: Establishing a test method for the manufacturing process. May-June 2003 Miyako Y, Tai H, Saitoh I, Ikeda K., Shionogi & Co., Ltd., Manuf READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Skin Tests and Conjunctival and Bronchial Challenges with Extracts of Blomia tro...
Votes:7 Comments:0
Skin Tests and Conjunctival and Bronchial Challenges with Extracts of Blomia tropicalis and Dermatophagoides pteronyssinus in Patients with Allergic Asthma and/or Rhinoconjunctivitis July 2003 J.C. READ MORE
http://content.karger.com/ProdukteDB/produkte.asp...

Comparative Study of Tolerance between Unmodified and High Doses of Chemically M...
Votes:21 Comments:0
Comparative Study of Tolerance between Unmodified and High Doses of Chemically Modified Allergen Vaccines of Dermatophagoides pteronyssinus March 2005 Miguel Casanovas, a, Enrique Fern?ndez-Caldas, READ MORE
http://content.karger.com/ProdukteDB/produkte.asp...

Humidity Considerations For Cold Shelf Loading
Votes:35 Comments:0
Humidity Considerations For Cold Shelf Loading 3/2/2005 VertMarkets, Inc. It is common practice during the production of a parenteral drug which is to eventually be freeze dried for the solution READ MORE
http://www.laboratorynetwork.com/content/news/article.asp...

Bonfiglioli Pharma Machinery Launch New Vacuum Tester For Lyophilised Vials
Votes:10 Comments:0
Bonfiglioli Pharma Machinery Launch New Vacuum Tester For Lyophilised Vials 7/5/2004 VertMarkets, Inc. A standard method for checking the vacuum in sealed vials containing freeze-dried (lyophilis READ MORE
http://www.laboratorynetwork.com/content/news/article.asp...

New VirTis Shell Bath Offers Efficiency And Convenience
Votes:5 Comments:0
New VirTis Shell Bath Offers Efficiency And Convenience 12/2/2004 VertMarkets, Inc. The new VirTis Benchtop Shell Bath is a self-contained, compact freezing unit designed for the laboratory benc READ MORE
http://www.laboratorynetwork.com/content/news/article.asp...

Datasheet: Sample Taking Device
Votes:18 Comments:0
Datasheet: Sample Taking Device 06/13/2005 Published By: Bolz-Summix, A Division of MPE Group, Inc. Bolz-Summix has developed a sample taking device that will work for sampling powders or liquids READ MORE
http://www.laboratorynetwork.com/Downloads/Detail.aspx...

Brochure: AdVantage Benchtop Freeze Dryers
Votes:32 Comments:0
Brochure: AdVantage Benchtop Freeze Dryers 05/19/2005 Published By: VirTis -- an SP Industries Company This new VirTis? AdVantage? Benchtop Freezer brochure from SP Industries focuses on the adv READ MORE
http://www.laboratorynetwork.com/Downloads/Detail.aspx...

Brochure: Winchester, UK: Training Course In Freeze Drying Technology
Votes:26 Comments:0
Brochure: Winchester, UK: Training Course In Freeze Drying Technology 03/11/2005 Published By: Biopharma Technology Limited The standard 3-day course will bring you up to date on the latest techn READ MORE
http://www.laboratorynetwork.com/Downloads/Detail.aspx...

Brochure: EZ-CFU?
Votes:21 Comments:0
Brochure: EZ-CFU? 11/30/2004 Published By: MicroBiologics, Inc. EZ-CFU? One Step, from MicroBioLogics Inc., is made to support growth promotion microorganism challenges that must meet USP/EP/JP READ MORE
http://www.laboratorynetwork.com/Downloads/Detail.aspx...

New warehouse addition will free up space in plant for envisioned second product...
Votes:5 Comments:0
New warehouse addition will free up space in plant for envisioned second production line January 27, 2005 By Linn Parish Journal Of Business Hollister-Stier Laboratories LLC, the Spokane pharma READ MORE
http://www.spokanejournal.com/index.php...

Air drying optimization of Saccharomyces cerevisiae through its waterglycerol de...
Votes:38 Comments:0
Air drying optimization of Saccharomyces cerevisiae through its waterglycerol dehydration properties April 2005 Y. Mille1, J.-P. Girard2, L. Beney1 and P. Gervais1 Journal of Applied Microbiology READ MORE
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2672.2005.0261...

Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamin...
Votes:38 Comments:0
Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics July 2003 Jordi Riba, Marta Valle, Gloria Urbano, Mercedes Yritia, Adelai READ MORE
http://jpet.aspetjournals.org/cgi/content/full/306/1/73

Potential of capillary electrophoresis for the monitoring of the stability of pl...
Votes:33 Comments:0
Potential of capillary electrophoresis for the monitoring of the stability of placental alkaline phosphatase February 2003 Eriksson HJ, Wijngaard M, Hinrichs WL, Frijlink HW, Somsen GW, de Jong GJ., READ MORE
http://www.sciencedirect.com/science...

Effects of types of sugar on the stabilization of protein in the dried state.
Votes:27 Comments:0
Effects of types of sugar on the stabilization of protein in the dried state. February 2003 Imamura K, Ogawa T, Sakiyama T, Nakanishi K., Department of Bioscience and Biotechnology, Faculty of Engin READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Injecting Excitement into Parenteral Drug Packaging
Votes:3 Comments:0
Injecting Excitement into Parenteral Drug Packaging April 2005 Jenevieve Blair Polin, Contributing Editor Medical DeviceLink Packaging for injectable parenteral drugs is changing its form and fu READ MORE
http://www.devicelink.com/pmpn/archive/05/04/003.html

Near-Infrared Analysis of Critical Parameters in Lyophilized Materials
Votes:36 Comments:0
Near-Infrared Analysis of Critical Parameters in Lyophilized Materials Abstract Near-infrared analysis presents itself as the QC method of choice for lyophilized materials due to its ability to READ MORE
http://www.thermo.com/eThermo/CMA/PDFs/Articles/articlesFile_26183.pdf

Microencapsulated chitosan nanoparticles for lung protein delivery
Votes:40 Comments:0
Microencapsulated chitosan nanoparticles for lung protein delivery Onlne May 2005 Ana Grenha, Bego?a Seijo and Carmen Remu??n-L?pez, University of Santiago de Compostela, Pharmacy and Pharmaceutica READ MORE
http://www.sciencedirect.com/science...

Novel sustained release microspheres for pulmonary drug delivery
Votes:35 Comments:0
Novel sustained release microspheres for pulmonary drug delivery May 5, 2005 Robert O. Cook, a, Rupi K. Pannu b, and Ian W. Kellaway a aDepartment of Pharmaceutics, University of London School of P READ MORE
http://www.sciencedirect.com/science...

The use of inverse gas chromatography and gravimetric vapour sorption to study t...
Votes:29 Comments:0
The use of inverse gas chromatography and gravimetric vapour sorption to study transitions in amorphous lactose April 27, 2005 Ameet V. Ambarkhane, a, Kim Pincott b, and Graham Buckton a aDepartmen READ MORE
http://www.sciencedirect.com/science...

Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and F...
Votes:5 Comments:0
Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G February 2005 Michael Maury, a, Keith Murphy, b, Sandeep Kumar, b, Alexan READ MORE
http://www.sciencedirect.com/science...

A study of the differences between two amorphous spray-dried samples of cefditor...
Votes:38 Comments:0
A study of the differences between two amorphous spray-dried samples of cefditoren pivoxil which exhibited different physical stabilities January 31, 2005 Masato Ohta a, b, and Graham Buckton a aDe READ MORE
http://www.sciencedirect.com/science...

Process characteristics and compaction of spray-dried emulsions containing a dru...
Votes:32 Comments:0
Process characteristics and compaction of spray-dried emulsions containing a drug dissolved in lipid December 2004 Tue Hansen, a, b, Per Holm, c and Kirsten Schultz, a aPharmaceutical Development, READ MORE
http://www.sciencedirect.com/science...

Rapid dissolving high potency danazol powders produced by spray freezing into li...
Votes:3 Comments:0
Rapid dissolving high potency danazol powders produced by spray freezing into liquid process Mfarch 1, 2004 Jiahui Hu, a, Keith P. Johnston, b and Robert O. Williams, III, a a Division of Pharmaceu READ MORE
http://www.sciencedirect.com/science...

Spray freezing into liquid (SFL) particle engineering technology to enhance diss...
Votes:35 Comments:0
Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems November 2003 Jiahui READ MORE
http://www.sciencedirect.com/science...

Micronized powders of a poorly water soluble drug produced by a spray-freezing i...
Votes:11 Comments:0
Micronized powders of a poorly water soluble drug produced by a spray-freezing into liquid-emulsion process March 2003 True L. Rogers, a, Kirk A. Overhoff, a, Parag Shah, b, Patricia Santiago, b, M READ MORE
http://www.sciencedirect.com/science...

In a Two-Chamber Cartridge DESCRIPTION GENOTROPIN Lyophilized ...
Votes:19 Comments:0
In a Two-Chamber Cartridge DESCRIPTION GENOTROPIN Lyophilized ... DESCRIPTION GENOTROPIN Lyophilized Powder contains somatropin [rDNA origin], which is a polypeptide hormone of recombinant DNA orig READ MORE
http://www.pfizer.com/pfizer/download/uspi_genotropin.pdf

Inulin could be new protein stabiliser
Votes:27 Comments:0
Inulin could be new protein stabiliser 03/02/2004 Drug Researcher.com The widely used food ingredient inulin could be a more effective alternative to established excipients in stabilising protein- READ MORE
http://www.drugresearcher.com/news/ng.asp...

LyoCheck from Thermo speeds up biopharma QC
Votes:17 Comments:0
LyoCheck from Thermo speeds up biopharma QC 22/06/2005 in-pharmatechnologist.com Thermo Electron has launched a new rapid method for the analysis of lyophilised (freeze-dried) materials using ts N READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Sanofi?s new Eloxatin consolidates its strong position
Votes:30 Comments:0
Sanofi?s new Eloxatin consolidates its strong position 09/02/2005 DrugResearcher.com FDA?s approval of Sanofi-Aventis? Eloxatin (oxaliplatin) is unlikely to increase the drug?s patient base, but t READ MORE
http://www.drugresearcher.com/news/ng.asp...

Cutting costs in contamination control
Votes:6 Comments:0
Cutting costs in contamination control 30/09/2004 in-pharmatechnologist.com One of the consequences of the new pharmaceutical legislation that came in last year is that companies involved in the ma READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Excipients overcome virus formulation challenge
Votes:19 Comments:0
Excipients overcome virus formulation challenge 13/07/2004 in-pharmatechnologist.com Viruses are increasingly being used as delivery vectors in the pharmaceutical industry, for example to deliver g READ MORE
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Research Questions Transplant Safety Procedure
Votes:28 Comments:0
Research Questions Transplant Safety Procedure 2004-04-01 source: Michigan State University Science Daily Lyophilization, a method once thought to inactivate retroviruses such as HIV from bones an READ MORE
http://www.sciencedaily.com/releases/2004/04/040401075329.htm

Surface adsorption of recombinant human interferon-? in lyophilized and spray-ly...
Votes:25 Comments:0
Surface adsorption of recombinant human interferon-? in lyophilized and spray-lyophilized formulations View Full Text (Wiley InterScience user account required) Author(s) Serena D. Webb, Stephen READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Low Molecular Weight Protamine (LMWP) as Nontoxic Heparin/Low Weight Heparin Ant...
Votes:20 Comments:0
Low Molecular Weight Protamine (LMWP) as Nontoxic Heparin/Low Weight Heparin Antidote (I): Preparation and Characterization Submitted: March 1, 2001; Accepted: June 7, 2001; Published: July 11, 2001 READ MORE
http://www.aapspharmsci.org/articles/ps0303/ps030317/ps030317.pdf

Preparation and Characterization of Poly(D,L-lactide-co-glycolide) Microspheres ...
Votes:34 Comments:0
Preparation and Characterization of Poly(D,L-lactide-co-glycolide) Microspheres for Controlled Release of Human Growth Hormone 2003 Yilmaz Capan,1 Ge Jiang,2 Stefano Giovagnoli,3 Kyu-Heum Na,4 a READ MORE
http://www.aapspharmscitech.org/view.asp...

Investigation and Physicochemical Characterization of Vinpocetine-Sulfobutyl Eth...
Votes:7 Comments:0
Investigation and Physicochemical Characterization of Vinpocetine-Sulfobutyl Ether b-Cyclodextrin Binary and Ternary Complexes 2003 Laura RIBEIRO,a Thorsteinn LOFTSSON,b Domingos FERREIRA,c and Fran READ MORE
http://www.jstage.jst.go.jp/article/cpb/51/8/914/_pdf

Optimization of Tablets Containing High Dose of Spray-Dried Plant Extract: A Tec...
Votes:40 Comments:0
Optimization of Tablets Containing High Dose of Spray-Dried Plant Extract: A Technical Note May 23, 2005 L.A.L. Soares1,2, G. Gonz?lez Ortega2, P.R. Petrovick2, P.C. Schmidt3 1 Departamento de Farm READ MORE
http://www.aapspharmscitech.org/prepub/Documents/AAPSPT-Soares-1788-pr...

Continuous Processing in Pharmaceutical Manufacturing
Votes:27 Comments:0
Continuous Processing in Pharmaceutical Manufacturing Matthew J. Mollan Jr., Ph.D. and Mayur Lodaya, Ph.D., Pfizer Inc. 1.0 Introduction Pharmaceutical processing in the manufacturing environment READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Freezing and Annealing Phenomena in Lyophilization: Effects Upon Primary Drying ...
Votes:40 Comments:0
Freezing and Annealing Phenomena in Lyophilization: Effects Upon Primary Drying Rate, Morphology, and Heterogeneity Theodore W. Randolph, Ph.D.1 & James A. Searles, Ph.D.2, 1University of Colorado, B READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Lyophilization - Points to Consider for Successful Process Transfer to Manufactu...
Votes:16 Comments:0
Lyophilization - Points to Consider for Successful Process Transfer to Manufacturing Stelios C. Tsinontides, Ph.D. Merck & Company Abstract Lyophilization (Freeze Drying) is widely used in the ph READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Strategies in Development of Lyophilized Parenteral
Votes:10 Comments:0
Strategies in Development of Lyophilized Parenterals Edward Trappler, Lyophilization Technology, Inc. For lyophilized parenteral preparations, as with any dosage form, product design parameters and READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

The Application of Thermoanalytical Techniques to the Study of the Freeze-Drying...
Votes:5 Comments:0
The Application of Thermoanalytical Techniques to the Study of the Freeze-Drying Proces Vicky Kett, Ph.D,.The School of Pharmacy, Queen's University of Belfast A key challenge facing the pharmaceut READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

The Impact of the Freezing Stage in Lyophilization: Effects of the Ice Nucleatio...
Votes:38 Comments:0
The Impact of the Freezing Stage in Lyophilization: Effects of the Ice Nucleation Temperature on Process Design and Product Quality Michael J. Pikal, Ph.D., Shailaja Rambhatla, and Roee Ramot, School READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Transferring the Lyophilization Process from One Freeze-Dryer to Another
Votes:32 Comments:0
Transferring the Lyophilization Process from One Freeze-Dryer to Another Dr. Thomas A. Jennings, Phase-Technologies Formulation: In order to simplify the discussion it will be assumed that the form READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Guidance for Industry on Drug Substance
Votes:5 Comments:0
Guidance for Industry on Drug Substance INTRODUCTION Information on the chemistry, manufacturing, and controls (CMC) for the drug substance must be submitted to support the approval of original new READ MORE
http://www.fda.gov/OHRMS/DOCKETS/98fr/2003d-0571-gdl0001.pdf

A sensitive and selective LC?MS?MS method for simultaneous determination of picr...
Votes:38 Comments:0
A sensitive and selective LC?MS?MS method for simultaneous determination of picroside-I and kutkoside (active principles of herbal preparation picroliv) using solid phase extraction in rabbit plasma: READ MORE
http://www.sciencedirect.com/science...

A COMPUTATIONAL MODEL FOR FINITE ELEMENT ANALYSIS OF THE FREEZE-DRYING PROCESS
Votes:33 Comments:0
A COMPUTATIONAL MODEL FOR FINITE ELEMENT ANALYSIS OF THE FREEZE-DRYING PROCESS 2004 Technalysis, Inc. W. J. Mascarenhas and H. U. Akay* Technalysis Inc., 7120 Waldemar Drive, Indianapolis, Indiana READ MORE
http://www.technalysis.com/newpage15.htm

Determination of mass and heat transfer parameters during freeze-drying cycles o...
Votes:27 Comments:0
Determination of mass and heat transfer parameters during freeze-drying cycles of pharmaceutical products. 2005 Mar-Apr Hottot A, Vessot S, Andrieu J. The PDA Journal of Pharmaceutical Science & Te READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Effects of RM-?-CD on sublingual bioavailability of ?9-tetrahydrocannabinol in r...
Votes:3 Comments:0
Effects of RM-?-CD on sublingual bioavailability of ?9-tetrahydrocannabinol in rabbits Received 31 January 2005; revised 15 April 2005; accepted 27 April 2005. Available online 13 June 2005. Ja READ MORE
http://www.sciencedirect.com/science...

Nanosizing: a formulation approach for poorly-water-soluble compounds
Votes:17 Comments:0
Nanosizing: a formulation approach for poorly-water-soluble compounds February 2003 Received 21 August 2002; revised 15 November 2002; accepted 18 November 2002. ; Available online 7 January 2003 READ MORE
http://www.sciencedirect.com/science...

Lyophilization of Biopharmaceuticals
Votes:25 Comments:0
Lyophilization of Biopharmaceuticals Not Dated By: Henry R. Costantino, Nastech /Pharmaceutical Company, Inc.; Michael J. Pikal, University of Connecticut American Association of Pharmaceutical Sc READ MORE
http://www.aapspharmaceutica.com/publications/press/summaries/Lyophile...

Biological Vial: More than Just a Pretty Package
Votes:14 Comments:0
Biological Vial: More than Just a Pretty Package February 1, 2005 No Author Listed Pharmaceutical Executive Biological products, derived from proteins, peptides, and enzymes, constitute a rapidly READ MORE
http://www.pharmexec.com/pharmexec/article/articleDetail.jsp...

Grants Given for Freeze-Dried Vaccine, Nutritious Tuber
Votes:27 Comments:0
Grants Given for Freeze-Dried Vaccine, Nutritious Tuber 29 June 2005 by: Marilyn Chase The Truth about Trade and Technology A program to conquer health problems of the poor is awarding rich gra READ MORE
http://www.truthabouttrade.org/article.asp...

Standardization of a neutralizing anti-vaccinia antibodies titration method: an ...
Votes:5 Comments:0
Standardization of a neutralizing anti-vaccinia antibodies titration method: an essential step for titration of vaccinia immunoglobulins and smallpox vaccines evaluation. 2005 Jan Leparc-Goffart I; READ MORE
http://intapp.medscape.com/px/medlineapp/getdoc...

Antibody persistence, PRP-specific immune memory, and booster responses in infan...
Votes:18 Comments:0
Antibody persistence, PRP-specific immune memory, and booster responses in infants immunised with a combination DTPa-HBV-IPV/Hib vaccine. Nov 2004 Nolan T; Altmann A; Skeljo M; Streeton C; Schuerma READ MORE
http://intapp.medscape.com/px/medlineapp/getdoc...

Vaccination success rate and reaction profile with diluted and undiluted smallpo...
Votes:13 Comments:0
Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial 2004 Sep 8 Talbot TR; Stapleton JT; Brady RC; Winokur PL; Bernstein DI; Germa READ MORE
http://intapp.medscape.com/px/medlineapp/getdoc...

GUIDE TO INSPECTIONS OF LYOPHILIZATION
Votes:39 Comments:0
GUIDE TO INSPECTIONS OF LYOPHILIZATION OF PARENTERALS July, 1993 Introduction Lyophilization or freeze drying is a process in which water is removed from a product after it is frozen and placed un READ MORE
http://bcg-usa.com/docs/1993/FDA199307B.pdf

In vitro studies on some probiotic properties of immobilised lactic acid bacteri...
Votes:14 Comments:0
In vitro studies on some probiotic properties of immobilised lactic acid bacteria after freezing and freeze-drying. Nazzaro F, Sorrentino A, Malinconico M, Orlando P. Institute of Food Science and T READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The biocompatibility of dibutyryl chitin in the context of wound dressings
Votes:9 Comments:0
The biocompatibility of dibutyryl chitin in the context of wound dressings. Biomaterials. 2005 Oct;26(29):5844-54. Epub 2005 Apr 26 Muzzarelli RA, Guerrieri M, Goteri G, Muzzarelli C, Armeni T, Ghis READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Effects of sucrose and mannitol on asparagine deamidation rates of model peptide...
Votes:4 Comments:0
Effects of sucrose and mannitol on asparagine deamidation rates of model peptides in solution and in the solid state. J Pharm Sci. 2005 Jun 28;94(8):1723-1735 [Epub ahead of print] Li B, O'meara MH READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Preparation of aggregate-free, low molecular weight amyloid-beta for assembly an...
Votes:17 Comments:0
Preparation of aggregate-free, low molecular weight amyloid-beta for assembly and toxicity assays. Methods Mol Biol. 2005;299:3-9 Bitan G, Teplow DB. Center for Neurologic Diseases, Brigham and Wom READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Aseptic Vial and Syringe Filling
Votes:31 Comments:0
Aseptic Vial and Syringe Filling Narlin B. Beaty, Ph.D. Sublimation Science LLC Like the preparation of a fine dinner, aseptic filling of vials and syringes is best performed with the highest quali READ MORE
http://www.sublimationscience.com/myCode/Publications/aseptic_filling....

Thermodynamic and dynamic factors involved in the stability of native protein st...
Votes:26 Comments:0
Thermodynamic and dynamic factors involved in the stability of native protein structure in amorphous solids in relation to levels of hydration August 2005 John J. Hill 1, Evgenyi Y. Shalaev 2, Georg READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110534130/ABSTRACT

Effect of dioxane on the structure and hydration?dehydration of a-chymotrypsin a...
Votes:21 Comments:0
Effect of dioxane on the structure and hydration?dehydration of a-chymotrypsin as measured by FTIR spectroscopy June 2005 Vladimir A. Sirotkin, Kazan State University, Butlerov Institute of Chemistr READ MORE
http://www.sciencedirect.com/science...

Synthesis and immunological studies of glycoconjugates of Cryptococcus neoforman...
Votes:34 Comments:0
Synthesis and immunological studies of glycoconjugates of Cryptococcus neoformans capsular glucuronoxylomannan oligosaccharide structures June 10, 2005 Stefan Oscarson, a, Mia Alpe, a, P?r Svahnberg READ MORE
http://www.sciencedirect.com/science...

Pharmacologically active microcarriers: a tool for cell therapy
Votes:10 Comments:0
Pharmacologically active microcarriers: a tool for cell therapy June 2005 V.M. Tatard, a, M.C. Venier-Julienne, a, P. Saulnier, a, E. Prechter, a, J.P. Benoit, a, P. Menei, a, b and C.N. Montero-Men READ MORE
http://www.sciencedirect.com/science...

Stability of Bortezomib 1-mg/mL Solution in Plastic Syringe and Glass Vial
Votes:23 Comments:0
Stability of Bortezomib 1-mg/mL Solution in Plastic Syringe and Glass Vial June 2005 Pascal Andr? 1, Salvatore Cisternino PharmD PhD2*, Fouad Chiadmi PharmD2, Audrey Toledano PharmD2, Jo?l Schlatte READ MORE
http://www.theannals.com/cgi/content/abstract/aph.1E620v1...

Porous scaffolds of gelatin-hydroxyapatite nanocomposites obtained by biomimetic...
Votes:37 Comments:0
Porous scaffolds of gelatin-hydroxyapatite nanocomposites obtained by biomimetic approach: Characterization and antibiotic drug release Published Online: 29 Jun 2005 Received: 21 June 2004; Revised: READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110551562/ABSTRACT

US: will potatoes help prevent hepatitis E?
Votes:13 Comments:0
US: will potatoes help prevent hepatitis E? June 1, 2005 FreshPlaza Researchers in the U.S. and Japan are trying to develop an oral vaccine to prevent hepatitis E ? with a little hard work, it may READ MORE
http://www.freshplaza.com/2005/01jun/2_us_hepatitisE.htm

Lab-scale freeze-drier launched in UK
Votes:34 Comments:0
Lab-scale freeze-drier launched in UK 6/23/05 LabTechnologist.com The Compaclyo range is aimed at product R&D, manufacture of clinical trial materials and small production batches, according to BP READ MORE
http://www.labtechnologist.com/news/news-ng.asp...

BOC Edwards Pharmaceutical Systems Signs ?7m Deal
Votes:10 Comments:0
BOC Edwards Pharmaceutical Systems Signs ?7m Deal July 6, 2005 Process Control Today BOC Edwards Pharmaceutical Systems has signed a ?7m deal to supply a combination of its engineered-to-order load READ MORE
http://www.pandct.com/media/shownews.asp...

Rapid QC analysis of lyophilised materials
Votes:24 Comments:0
Rapid QC analysis of lyophilised materials June 22, 2005 Laboratorytalk Thermo Electron announces the LyoCheck - a rugged, easy-to-use package that provides a rapid method for the analysis of lyoph READ MORE
http://www.laboratorytalk.com/news/tct/tct118.html

Lactobacillus paracasei Strain ST11 Has No Effect on Rotavirus but Ameliorates t...
Votes:19 Comments:0
Lactobacillus paracasei Strain ST11 Has No Effect on Rotavirus but Ameliorates the Outcome of Nonrotavirus Diarrhea in Children From Bangladesh. July 1, 2005 Sarker SA, Sultana S, Fuchs GJ, Alam NH, READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

IgG replacement by the subcutaneous route using preparations licensed in the USA...
Votes:13 Comments:0
IgG replacement by the subcutaneous route using preparations licensed in the USA for administration by other routes February 2004 K.A. Duff, a, S. Roy, b, J. Pollb, M. Berger,b aAllergy and Immuno READ MORE
http://www2.us.elsevierhealth.com/scripts/om.dll/serve...

Preclinical characterization of a new liquid ?immune globulin intravenous (human...
Votes:8 Comments:0
Preclinical characterization of a new liquid ?immune globulin intravenous (human), 10% triple virally reduced solution? (IGIV, 10%TVR) February 2004 W. Teschner, IV a, W. Auerb, L. Pichlerc, U. B?lz READ MORE
http://www2.us.elsevierhealth.com/scripts/om.dll/serve...

American Association of Tissue Banks
Votes:33 Comments:0
American Association of Tissue Banks 1320 Old Chain Bridge Rd., Suite 450, McLean, Virginia 22101. The American Association of Tissue Banks (AATB) is a scientific, not-for-profit, peer group organ READ MORE
http://www.aatb.org/

Drug design and development capabilities.(Industry Pipeline)(Lyophilization Tech...
Votes:17 Comments:0
Drug design and development capabilities.(Industry Pipeline)(Lyophilization Technology ) 3/1/2005 Pharmaceutical Technology Lyophilization Technology offers drug development capabilities for highl READ MORE
http://www.highbeam.com/library/doc0.asp...

Directory of lyphilization service providers
Votes:11 Comments:0
Directory of lyphilization service providers 2/1/2004 Pharmaceutical Technology Directory of lyophilization services providers. Prelyophilization Lyophiliz READ MORE
http://www.highbeam.com/library/doc0.asp...

Contract lyophilization services: focus on identifying and optimizing critical p...
Votes:25 Comments:0
Contract lyophilization services: focus on identifying and optimizing critical process parameters 2/1/2003 Pharmaceutical Processing Company offers contract lyophilization services that focus on i READ MORE
http://www.highbeam.com/library/doc0.asp...

Parenteral contract manufacturing
Votes:19 Comments:0
Parenteral contract manufacturing 9/1/2003 Pharmaceutical Technology Baxter Pharmaceutical Solutions is a parenteral contract manufacturer. Services include vial-filling, lyophilization, syringe-fi READ MORE
http://www.highbeam.com/library/doc0.asp...

"BioBall" technology brings precision cell-counting to freeze-drying
Votes:14 Comments:0
"BioBall" technology brings precision cell-counting to freeze-drying 4/1/2004 Bates, Megyn Pharmaceutical Technology Pharmaceutical scientists have long sought a reliable method of freeze-drying l READ MORE
http://www.highbeam.com/library/doc0.asp...

Freeze drying systems: www.SPindustries.com
Votes:28 Comments:0
Freeze drying systems: www.SPindustries.com 5/1/2005 Pharmaceutical Processing Hull freeze drying systems (lyophilizers) are engineered to pharmaceutical cGMP standards. Hull provides project sup READ MORE
http://www.highbeam.com/library/doc0.asp...

STERIS Corporation
Votes:22 Comments:0
STERIS Corporation 11/1/2003 Pharmaceutical Processing Product Line: STERIS is a world leader in the manufacture of FDA, cGMP and GAMP-compliant LYOVAC[R] freeze-drying systems, which are built to READ MORE
http://www.highbeam.com/library/doc0.asp...

Manufacturing technology choices for mouth dissolving tablets: mouth dissolving ...
Votes:36 Comments:0
Manufacturing technology choices for mouth dissolving tablets: mouth dissolving tablets have great potential in the pharmaceutical industry and are prepared using various techniques such as freeze-dry READ MORE
http://www.highbeam.com/library/doc0.asp...

Freeze-drying services
Votes:12 Comments:0
Freeze-drying services 5/1/2005 Medical Device Technology Lyofal specialises in lyophilisation, a technique of natural drying under cold and vacuum conditions. The company owns 25 freeze driers of READ MORE
http://www.highbeam.com/library/doc0.asp...

pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formu...
Votes:6 Comments:0
pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation August 2005 Viktor Peikov, Sydney Ugwu, Manjeet Parmar, Allen Zhang and Imran Ahmad, Research & Development, Ne READ MORE
http://www.sciencedirect.com/science...

Angiotensin I converting enzyme (ACE) inhibitory peptide derived from the sauce ...
Votes:20 Comments:0
Angiotensin I converting enzyme (ACE) inhibitory peptide derived from the sauce of fermented blue mussel, Mytilus edulis September 2004 Je JY, Park PJ, Byun HG, Jung WK, Kim SK., Department of Chemi READ MORE
http://www.sciencedirect.com/science...

Effect of the covalent modification of horseradish peroxidase with poly(ethylene...
Votes:14 Comments:0
Effect of the covalent modification of horseradish peroxidase with poly(ethylene glycol) on the activity and stability upon encapsulation in polyester microspheres Al-Azzam W, Pastrana EA, King B, Me READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/110549293/ABSTRACT

Application of on-line Raman spectroscopy for characterizing relationships betwe...
Votes:9 Comments:0
Application of on-line Raman spectroscopy for characterizing relationships between drug hydration state and tablet physical stability 2005 Jun 22 Hausman DS, Cambron RT, Sakr A. Int J Pharm. Indus READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Drying in Pharmaceutical and Biotechnological Industries
Votes:4 Comments:0
Drying in Pharmaceutical and Biotechnological Industries 2003 SAGE Publications M. Guerrero Ferrer International S.A., R&D Center, Juan de Sada 32 08028 Barcelona, Spain mguerrero-research@ferrer READ MORE
http://fst.sagepub.com/cgi/content/abstract/9/3/237

Young PhD makes progress on pharmaceutical drying techniques
Votes:17 Comments:0
Young PhD makes progress on pharmaceutical drying techniques February 18, 2005 University of Saskatchewan The U of S has its own Doogie Howser. And although he may not be a teenage whiz-kid doctor READ MORE
http://www.usask.ca/communications/ocn/05-feb-18/profile01.shtml

The dynamic calibration of an electrical capacitance tomography sensor applied t...
Votes:16 Comments:0
The dynamic calibration of an electrical capacitance tomography sensor applied to the fluidized bed drying of pharmaceutical granule 2005 Gareth Chaplin1, Todd Pugsley1, Loni van der Lee2, Apostolos READ MORE
http://www.iop.org/EJ/abstract/0957-0233/16/6/007

Outsourcing Outlook
Votes:24 Comments:0
Outsourcing Outlook March 2003 Jim Miller, PharmSource Information Services, Inc. Pharmaceutical Technology Contract research and manufacturing is entering 2003 on a high note with strong fourth-q READ MORE
http://www.pharmtech.com/pharmtech/data/articlestandard/pharmtech/1120...

Beacon Pharma gets going by Jan next
Votes:8 Comments:0
Beacon Pharma gets going by Jan next 7/15/2005 Financial Express Beacon Pharmaceuticals Ltd, a Tk 1.30 billion plant designed to produce high-tech anti-cancer medicines, will start operation b READ MORE
http://www.financialexpress-bd.com/index3.asp...

Evaluation of a Candidate International Standard Preparation for Human Anti-Toxo...
Votes:22 Comments:0
Evaluation of a Candidate International Standard Preparation for Human Anti-Toxoplasma Immunoglobulin G November 2004 Peter Rigsby,1 Sjoerd Rijpkema,2* Edward C. Guy,3 Janet Francis,3 and Rose Gaine READ MORE
http://jcm.asm.org/cgi/content/abstract/42/11/5133...

Dielectric properties of residual water in amorphous lyophilized mixtures of sug...
Votes:16 Comments:0
Dielectric properties of residual water in amorphous lyophilized mixtures of sugar and drug January 2003 R El Moznine1, G Smith1,3, E Polygalov1, P M Suherman1 and J Broadhead2 1 School of Pharmac READ MORE
http://www.iop.org/EJ/abstract/0022-3727/36/4/302/

Characterization of cirrhosis and hepatocellular carcinoma using low-angle x-ray...
Votes:30 Comments:0
Characterization of cirrhosis and hepatocellular carcinoma using low-angle x-ray scattering signatures of serum August 2003 Wael M Elshemey1, Omar S Desouky2, Mohammed S Mohammed3, Anwar A Elsayed1 READ MORE
http://www.iop.org/EJ/S/UNREG/uKlUmlY746qGxb8W3dqZUA/abstract/-search=...

FDA Approves New Paclitaxel Formulation
Votes:22 Comments:0
FDA Approves New Paclitaxel Formulation 10 January 2005 Cheryl A. Thompson American Society of Health-System Pharmacists BETHESDA, MD, 10 January 2005 ? Abraxane, a formulation of paclitaxel that READ MORE
http://www.ashp.org/news/ShowArticle.cfm...

Radiopharmaceutical development of a freeze-dried kit formulation for the prepar...
Votes:24 Comments:0
Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis 2004 Author(s) Elisa READ MORE
http://www.aapspharmaceutica.com/search/view.asp...

Detection of Autoantibodies to Protein Tyrosine Phosphatase-like Protein IA-2 wi...
Votes:19 Comments:0
Detection of Autoantibodies to Protein Tyrosine Phosphatase-like Protein IA-2 with a Novel Time-resolved Fluorimetric Assay 2003 Annette Westerlund-Karlsson1,a, Katriina Suonp??2, Matti Ankelo1, Jor READ MORE
http://www.clinchem.org/cgi/content/abstract/49/6/916...

Freeze drying with extra flexibility
Votes:13 Comments:0
Freeze drying with extra flexibility 15 July 2005 Laboratory talk Freeze dryer has been engineered to handle all applications from phase one research to production clinical trial batches Note: A f READ MORE
http://www.laboratorytalk.com/news/bop/bop111.html

Avant, Harvard to develop cholera vaccine
Votes:21 Comments:0
Avant, Harvard to develop cholera vaccine July 18, 2005 By Steve Mitchell United Press International World Peace Herald WASHINGTON -- The National Institutes of Health has awarded nearly $500,0 READ MORE
http://www.wpherald.com/storyview.php...

A membrane-lid tube for bacteria cultivation and freeze-drying
Votes:10 Comments:0
A membrane-lid tube for bacteria cultivation and freeze-drying April 2, 2003 Wilhelm Bockelmann, Institut f?r Mikrobiologie, Bundesanstalt f?r Milchforschung; Kiel, Germany Susanne Wagner, Eppendor READ MORE
http://www.biocompare.com/techart.asp...

Evidence That the Amino-Terminal Composition of Non-(1?84) Parathyroid Hormone F...
Votes:5 Comments:0
Evidence That the Amino-Terminal Composition of Non-(1?84) Parathyroid Hormone Fragments Starts before Position 19 January 2005 Pierre D?Amour1,2,a, Jean-Hugues Brossard1,2, Agn?s R?kel1,2, Louise READ MORE
http://www.clinchem.org/cgi/content/abstract/51/1/169...

Formulation & Delivery of Protein and Peptide Biopharmaceuticals:Multidose Formu...
Votes:32 Comments:0
Formulation & Delivery of Protein and Peptide Biopharmaceuticals:Multidose Formulations 2005 Integrity Biosolution Multidose Formulations Multidose formulation should be used when dose adjustment, READ MORE
http://www.integritybio.com/multidose%20formulation.htm

Fast, flexible freeze drying at the lab bench
Votes:21 Comments:0
Fast, flexible freeze drying at the lab bench May 16, 2005 Laboratorytalk Range of condenser temperature options provides all the drying power required to freeze dry aqueous and most organic-based READ MORE
http://www.laboratorytalk.com/news/bop/bop109.html

HollisterStier to add second freeze-drying system in Spokane
Votes:35 Comments:0
HollisterStier to add second freeze-drying system in Spokane Jun 2, 2005 by Tom Sowa Spokesman Review, The (Spokane) HollisterStier Laboratories LLC, one of Spokane's most successful manufactur READ MORE
http://www.findarticles.com/p/articles/mi_qn4186/is_20050602/ai_n14654...

With Plasma, There?s No Immunity From Challenges
Votes:29 Comments:0
With Plasma, There?s No Immunity From Challenges July 2005 by Pan Demetrakakes Food & Drug Packaging The immunoglobulin therapies packaged at the main Talecris plant are among the most demanding READ MORE
http://www.fdp.com/content.php...

Measurement of the Kinetics of Protein Unfolding in Viscous Systems and Implicat...
Votes:30 Comments:0
Measurement of the Kinetics of Protein Unfolding in Viscous Systems and Implications for Protein Stability in Freeze-Drying July 2005 Tang XC, Pikal MJ., School of Pharmacy, U-2092, University of Co READ MORE
http://www.springerlink.com/app/home/contribution.asp...

Effect of counterions on the physical properties of l-arginine in frozen solutio...
Votes:6 Comments:0
Effect of counterions on the physical properties of l-arginine in frozen solutions and freeze-dried solids July 2005 Ken-Ichi Izutsu, Yasuto Fujimaki, Akiko Kuwabara and Nobuo Aoyagi, National Insti READ MORE
http://www.sciencedirect.com/science...

Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate ...
Votes:38 Comments:0
Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate from patients undergoing continuous veno-venous hemodiafiltration by HPLC July 18, 2005 A. Isla, a, A. Arzuaga, a, J. READ MORE
http://www.sciencedirect.com/science...

Polymer nanocarriers protecting active enzyme cargo against proteolysis
Votes:33 Comments:0
Polymer nanocarriers protecting active enzyme cargo against proteolysis February 2005 Thomas D. Dziubla, a, Adnan Karim, a and Vladimir R. Muzykantova, b a Institute for Environmental Medicine, Un READ MORE
http://www.sciencedirect.com/science...

Biological Activity of Opuntia ficus indica Cladodes II: Effect on Experimental ...
Votes:8 Comments:0
Biological Activity of Opuntia ficus indica Cladodes II: Effect on Experimental Hypercholesterolemia in Rats May 2003 E.M. Galati, M.M. Tripodo, A. Trovato, A. d?Aquino, M.T. Monforte Pharmaceutica READ MORE
http://journalsonline.tandf.co.uk/app/home/contribution.asp...

Use of Block Copolymers of Poly(Ortho Esters) and Poly (Ethylene Glycol) Micella...
Votes:3 Comments:0
Use of Block Copolymers of Poly(Ortho Esters) and Poly (Ethylene Glycol) Micellar Carriers as Potential Tumour Targeting Systems July 2003 V. Toncheva A1, E. Schacht A1, S.Y. Ng A2, J. Barr A2, J. H READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The Effects of Enterococcus faecium and Selenium on Methotrexate Treatment in Ra...
Votes:17 Comments:0
The Effects of Enterococcus faecium and Selenium on Methotrexate Treatment in Rat Adjuvant-induced Arthritis September/December 2004 Jozef Rovensk? A1, Karol ?v?k A1, Vladim?r Matha A1, Richard I READ MORE
http://journalsonline.tandf.co.uk/app/home/contribution.asp...

Engineered unit enters new market with $20 mln deal
Votes:31 Comments:0
Engineered unit enters new market with $20 mln deal St. Louis Business Journal July 15, 2005 Engineered Support Systems' Inc.'s Radian Inc. has been reinforcing U.S. Army trucks against roadside bo READ MORE
http://stlouis.bizjournals.com/stlouis/stories/2005/07/11/daily77.html

Nanotechnology delivers military power
Votes:25 Comments:0
Nanotechnology delivers military power May 2005 By Ben Ames Military & Aerospace Electronics Army leaders are looking for a 21st century battlesuit. The lycra-tight clothing must stop bullets, d READ MORE
http://mae.pennnet.com/articles/article_display.cfm...

Vetter Pharma-Fertigung Launches Major Expansion
Votes:39 Comments:0
Vetter Pharma-Fertigung Launches Major Expansion June 22, 2005 PharmaManufacturing.com Vetter Pharma-Fertigung GmbH & Co. KG (Ravensburg, Germany), an international contract manufacturer with a foc READ MORE
http://www.pharmamanufacturing.com/industrynews/2005/277.html

Hospira Invests Nearly $200 Million to Expand Biologics Contract Manufacturing P...
Votes:36 Comments:0
Hospira Invests Nearly $200 Million to Expand Biologics Contract Manufacturing Plant 07/26/2005 PharmaManufacturing.com Industrialinfo.com reported July 26 that Hospira (Lake Forest, Ill.) has comp READ MORE
http://www.pharmamanufacturing.com/industrynews/2005/309.html

The physical characteristics of lyophilized tablets containing a model drug in d...
Votes:12 Comments:0
The physical characteristics of lyophilized tablets containing a model drug in different chemical forms and concentrations. January 1, 2005 M Sznitowska, M Placzek, and M Klunder Acta Pol Pharm Hi READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;16022490...

Stabilization of alum-adjuvanted vaccine dry powder formulations: Mechanism and ...
Votes:7 Comments:0
Stabilization of alum-adjuvanted vaccine dry powder formulations: Mechanism and application February 1, 2003 YF Maa, L Zhao, LG Payne, and D Chen Journal of Pharmaceutical Sciences HighWire Press READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;12532382...

Freeze-Drying Human Red Blood Cells: Effect of Hematocrit and Composition of the...
Votes:39 Comments:0
Freeze-Drying Human Red Blood Cells: Effect of Hematocrit and Composition of the Freeze-Drying Medium on Red Cell Survival. 2004 Gyana R. Satpathy, PhD1,*, Zsolt Torok, PhD1,*, Mitali Banerjee, Ph READ MORE
http://meeting.bloodjournal.org/cgi/content/abstract/104/11/4093...

Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate ...
Votes:15 Comments:0
Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate Their Intracellular pH. 2004 Fern Tablin, VMD, PhD1, Minke Tang, PhD1,2,*, Naomi J. Walker, BS1,* and John H. Crowe, READ MORE
http://meeting.bloodjournal.org/cgi/content/abstract/104/11/3638...

The preparation and characterisation of drug-loaded alginate and chitosan sponge...
Votes:10 Comments:0
The preparation and characterisation of drug-loaded alginate and chitosan sponges. January 30, 2003 HL Lai, A Abu'Khalil, and DQ Craig International Journal of Pharmaceutics HighWire Press The S READ MORE
http://highwire.stanford.edu/cgi/medline/pmid;12527187...

Method for the Assessment of Ocular Distribution of Pharmacological Agents
Votes:4 Comments:0
Method for the Assessment of Ocular Distribution of Pharmacological Agents 2005 A.M. Laties1,A,2 and C. Mitchell1,B Investigative Ophthalmology & Visual Science Commercial Relationships: A.M. La READ MORE
http://abstracts.iovs.org/cgi/content/abstract/46/5/3531...

Ocular Surface in vivo Tolerance to New Nanoparticulate Polymer Systems Designed...
Votes:18 Comments:0
Ocular Surface in vivo Tolerance to New Nanoparticulate Polymer Systems Designed for Drug Delivery 2005 Y. Diebold1, A. Enr?quez de Salamanca1, M. Calonge1, A. Vila2, E.L. S. Carvalho2, M. de la Fue READ MORE
http://abstracts.iovs.org/cgi/content/abstract/46/5/2048...

The characterization and biodistribution of cefoxitin-loaded liposomes
Votes:31 Comments:0
The characterization and biodistribution of cefoxitin-loaded liposomes 1 March 2004 Received 30 June 2003; revised 14 October 2003; accepted 22 October 2003. ; Available online 14 December 2003. READ MORE
http://www.sciencedirect.com/science...

Structural and rheological characterization of Scleroglucan/borax hydrogel for d...
Votes:26 Comments:0
Structural and rheological characterization of Scleroglucan/borax hydrogel for drug delivery September 2003 Received 4 October 2002; revised 25 March 2003; accepted 10 April 2003. ; Available onl READ MORE
http://www.sciencedirect.com/science...

Novel polyester-polysaccharide nanoparticles.
Votes:21 Comments:0
Novel polyester-polysaccharide nanoparticles. 2003 Aug Lemarchand C, Couvreur P, Besnard M, Costantini D, Gref R. Pharm Res. Entrez PubMed UMRCNRS 8612, School of Pharmacy, Chatenay Malabry, Fra READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

FDA Sends Warning Letter to Merck and Company, Inc.
Votes:23 Comments:0
Please clarify the steps that your firm will take toward modernizing your specification/characterization procedures and practices. Currently, you have produced [redacted] lots of Asparaginase Intermed READ MORE
http://www.medadnews.com/News/Index.cfm...

Freeze-Drying ? an Art or a Science?
Votes:18 Comments:0
Although techniques for the study of Tg? are well established, there has been little commercially available equipment for the study of Tc itself until the launch of the BTL ?Lyostat? freeze-drying mic READ MORE
http://www.lyophilizationtechnology.com/freezeart.htm

Eudragit RS100? nanosuspensions for the ophthalmic controlled delivery of ibupro...
Votes:32 Comments:0
This is a subscription site. You will need to register and pay to view the Full Text Article. READ MORE
http://www.sciencedirect.com/science...

Center works to bring life to that which is ?dead?
Votes:8 Comments:0
Blood banks show interest The No. 1 clinical problem with transfusion of platelets from blood banks is septic shock, caused by bacterial contamination, Tablin said. It's a particular problem for U.S READ MORE
http://www.dateline.ucdavis.edu/dl_detail.lasso...

Environmental Monitoring in Pharmaceutical Manufacturing - A Product Risk Issue
Votes:29 Comments:0
The objective of a risk-based approach is to use scientific data and principles to assess the relative risk/benefit value of specific control measures. In the case of aseptically-filled parenteral pro READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Forced Degradation of Pharmaceuticals
Votes:5 Comments:0
Mass Balance Assessments of bass balance in degradation studies checks to see if the amount of material detected in a stressed sample matches the amount present before stress was applied. The assay f READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

Improving Vaccine Stability, Potency, and Delivery
Votes:19 Comments:0
Early input of formulation research is important since it may significantly reduce product development cycle times by avoiding the selection of labile candidates and screening out potential bad actors READ MORE
http://www.americanpharmaceuticalreview.com/article.aspx...

CMOs Attack Biomanufacturing Market
Votes:13 Comments:0
Vetter Broadens Capabilities Another major player in the European contract manufacturing arena has announced expansion plans, this time for the fill-and-finish (sterile injectable manufacturing) seg READ MORE
http://www.ptemag.com/pharmtecheurope/article/articleDetail.jsp...

Biological Vial: More than Just a Pretty Package
Votes:5 Comments:0
What are manufacturers' main concerns for packaging? They want components that operate well with their filling lines and their full range of processing. If every time they run 1,000 stoppers down the READ MORE
http://www.pharmexec.com/pharmexec/article/articleDetail.jsp...

Azacitidine: A novel agent for myelodysplastic syndromes
Votes:8 Comments:0
14 Christman JK, Mendelsohn N, Herzog D et al. Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60). Cancer Res. 1983; 43:763Ò9. 15 Creusot F, READ MORE
http://www.ajhp.org/cgi/content/full/62/15/1567...

Surface contamination of chemotherapy drug vials and evaluation of new vial-clea...
Votes:22 Comments:0
1 Edwards BK, Howe HL, Ries LA et al. Annual report to the nation on the status of cancer, 1973?1999, featuring implications of age and aging on the U.S. cancer burden. Cancer. 2002; 94:2766?92. 2 A READ MORE
http://www.ajhp.org/cgi/content/full/62/5/475...

Healing power of age-old therapy
Votes:25 Comments:0
TCM as an art Dr Chang does agree that TCM needs to be modernized. But its modernization should put more emphasis on improving prescription preparation with the help of modern science, he suggeste READ MORE
http://news.xinhuanet.com/english/2005-09/21/content_3520081.htm

Vaccines on the Road to Recovery
Votes:18 Comments:0
Improving manufacturing But production of the vaccines could be a problem, according to a report published last year by the International AIDS Vaccine Initiative. The report cites two main challenge READ MORE
http://www.dddmag.com/ShowPR.aspx...

The process development challenge for a new vaccine
Votes:37 Comments:0
The second critical step in the process was to make a vaccine for rapid evaluation in the clinic (assessed by its ability to generate antibodies against the HPV virus), recognizing that the method use READ MORE
http://www.nature.com/nm/journal/v11/n4s/full/nm1218.html

Biocatalysis in semi-aqueous and nearly anhydrous conditions
Votes:7 Comments:0
You can view the abstract online. A subscription is required to view the full text or it can be purchased online. READ MORE
http://www.sciencedirect.com/science...

Pharmaceutical Drying Technology
Votes:8 Comments:0
Pharmaceutical Drying Technology Richard Taylor & Suling Zhai Department of Chemical Engineering University of Cambridge, Cambridge CB2 3RA, UK Overview Dry pharmaceutical formulations are re READ MORE
http://www.cheng.cam.ac.uk/exemplarch2002/sz216/index.html

Vetter keeps on expanding lyophilisation services
Votes:7 Comments:0
Vetter keeps on expanding lyophilisation services 11/08/2006 by Emilie Reymond In-PharmaTechnologist.com Germany?s Vetter Pharma-Fertigung has announced its plan to expand its services by adding READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

Lyophilization is not a freeze-dried technology
Votes:32 Comments:0
Lyophilization is not a freeze-dried technology 01 October 2006 By: Louis Rey, Florence Lhospice Pharmaceutical Technology Europe Almost 100 years after its initial development, lyophilizat READ MORE
http://www.ptemag.com/pharmtecheurope/article/articleDetail.jsp...

Baxter expands lyophilisation capacity
Votes:26 Comments:0
Baxter expands lyophilisation capacity 12/07/2006 by Emilie Reymond in-Pharmatechnologist.com Baxter is expanding its lyophilisation capacity at its German facility to support future growth of i READ MORE
http://www.in-pharmatechnologist.com/news/ng.asp...

The Market Need for Reconstitution Systems
Votes:40 Comments:0
The Market Need for Reconstitution Systems 11/2006 By Graham Reynolds Vice President, Reconstitution and Transfer Systems West Pharmaceutical Services, Inc. Pharmaceutical Processing As the numb READ MORE
http://www.pharmpro.com/ShowPR.aspx...

GSK invests in vaccine factory
Votes:24 Comments:0
GSK invests in vaccine factory Sep 30 2006 By The Journal Drugs firm GlaxoSmithKline is investing more than ?339m into a French factory to boost vaccine manufacturing capacity. The pharmaceutica READ MORE
http://icnewcastle.icnetwork.co.uk/0500business/businessnews/tm_object...

Pace quickens at Hollister-Stier
Votes:19 Comments:0
Pace quickens at Hollister-Stier December 21, 2006 By Emily Brandler Spokane Journal of Business Spokane drug manufacturer Hollister-Stier Laboratories LLC, which has launched a roughly $30 mil READ MORE
http://www.spokanejournal.com/spokane_id=article&sub=3000

In vitro release of a water-soluble agent from low viscosity biodegradable, inje...
Votes:9 Comments:0
In vitro release of a water-soluble agent from low viscosity biodegradable, injectable oligomers Received 14 June 2006; revised 14 September 2006; accepted 20 September 2006. Available online 28 READ MORE
http://www.sciencedirect.com/science...

Parameters affecting the drug release from in situ gelling nasal inserts
Votes:3 Comments:0
Parameters affecting the drug release from in situ gelling nasal inserts Received 18 July 2005; revised 11 October 2005; accepted 28 November 2005. Available online 2 March 2006. Ulrike Bertra READ MORE
http://www.sciencedirect.com/science...

Impact of freezing procedure and annealing on the physico-chemical properties an...
Votes:31 Comments:0
Impact of freezing procedure and annealing on the physico-chemical properties and the formation of mannitol hydrate in mannitol?sucrose?NaCl formulations Received 3 April 2006; revised 7 June 2006 READ MORE
http://www.sciencedirect.com/science...

Physico-chemical lyophilization behavior of mannitol, human serum albumin formul...
Votes:6 Comments:0
Physico-chemical lyophilization behavior of mannitol, human serum albumin formulations Received 23 November 2005; revised 14 February 2006; accepted 18 February 2006. Available online 28 Februar READ MORE
http://www.sciencedirect.com/science...

DRAXIS Manufacturing Facilities Pass Extensive FDA Inspection
Votes:9 Comments:0
DRAXIS Manufacturing Facilities Pass Extensive FDA Inspection May 30 2007 Industry Canada:Pharmaceuticals DRAXIS Health Inc. (Mississagua) has received notification from the US Food and Drug Admi READ MORE
http://strategis.ic.gc.ca/epic/site/p-pp.nsf/en/h_ph00010e.html

Drug Reconstitution: Market Needs and Technical Challenges
Votes:26 Comments:0
Drug Reconstitution: Market Needs and Technical Challenges March 2007 By: Graham Reynolds Controlled Environments Magazine Many reconstituted drugs are administered at home by the patient. Diffe READ MORE
http://www.cemag.us/articles.asp...

SRI International and Blanca Pharmaceuticals Collaborate to Develop Antibiotics ...
Votes:26 Comments:0
SRI International and Blanca Pharmaceuticals Collaborate to Develop Antibiotics for Drug-Resistant Infections March 28, 2007 SRI MENLO PARK, Calif. -- March 28, 2007 -- SRI International, an ind READ MORE
http://www.sri.com/news/releases/032807.html

AAIPharma Grows and Strengthens Parenteral Manufacturing and Sterile Product Rel...
Votes:10 Comments:0
AAIPharma Grows and Strengthens Parenteral Manufacturing and Sterile Product Release Capabilities Apr 03, 2007 SmartBrief WILMINGTON, N.C.-- (BUSINESS WIRE) -- AAIPharma Inc. announced today the READ MORE
http://www.smartbrief.com/news/bio/industryBW-detail.jsp...

Riding the IT Success Wave
Votes:37 Comments:0
Riding the IT Success Wave April 27, 2007 By Seema Singh Red Herring Indian life sciences industry builds momentum in contract services. The wave started with information technology and has no READ MORE
http://www.redherring.com/Article.aspx...

Jubilant Organosys completes acquisition of Hollister-Stier Laboratories
Votes:24 Comments:0
Jubilant Organosys completes acquisition of Hollister-Stier Laboratories 01 June 2007 Jubilant Organosys Jubilant Organosys completes acquisition of Hollister-Stier Laboratories Further streng READ MORE
http://www.jubl.com/news_desc.jsp...

Hyaluron to Expand its Burlington, Massachusetts Facility
Votes:40 Comments:0
Hyaluron to Expand its Burlington, Massachusetts Facility 2/14/2007 Expansion Management BURLINGTON, Mass. (February 14, 2007) ? The company will receive a $1 million low interest loan to expand READ MORE
http://www.expansionmanagement.com/smo/articleviewer/default.asp...
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