Use of buckysome or carbon nanotube for drug delivery - Patents

Use of buckysome or carbon nanotube for drug delivery

Agent: Williams, Morgan & Amerson - Houston, TX, US
Inventors: Andreas Hirsch, Uri Sagman, Stephen R. Wilson
Class: 424450000 (USPTO)
Related Patents: Drug, Bio-affecting And Body Treating Compositions, Preparations Characterized By Special Physical Form, Liposomes
#20060127470
06/15/06
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is covalently bonded to the carbon nanotubes.
[0001] This application claims priority from copending provisional application 60/356,856, filed Feb. 14, 2002, the disclosure of which is hereby incorporated by reference in its entirety.
BACKGROUND OF THE INVENTION
[0002] 1. Field of the Invention
[0003] The present invention relates to compositions and methods for administering a therapeutic agent to a mammal. More particularly, it relates to vesicles, wherein the vesicle wall comprises substituted fullerenes and the vesicle comprises the therapeutic agent; derivatized carbon nanotubes, wherein the carbon nanotubes are derivatized with the therapeutic agent; and methods for administering the vesicles or derivatized carbon nanotubes to a mammal.
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