Synthesis, deprotection, analysis and purification of RNA and ribozymes

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Synthesis, deprotection, analysis and purification of RNA and ribozymes
United States Patent 7,041,817
Usman , et al.
May 9, 2006
Inventors: Usman; Nassim (Boulder, CO); Wincott; Francine (Longmont, CO); Sweedler; David (Louisville, CO); Beigelman; Leonid (Longmont, CO); Dudycz; Lech W. (Worcester, MA); Grimm; Susan (Boulder, CO); DiRenzo; Anthony (Boulder, CO); Tracz; Danuta (Boulder, CO)
Assignee: Sirna Therapeutics, Inc. (Boulder, CO)
Appl. No.: 231874
Filed: August 30, 2002
Abstract
Method for purification and synthesis of RNA molecules and enzymatic RNA molecules in enzymatically active form.