Solid dispersion composition

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Title: Solid dispersion composition
United States Patent: 6,753,330
Issued: June 22, 2004
Inventors: Takano; Niichiro (Fuji, JP); Kawashima; Hiroyuki (Fuji, JP); Shinoda; Yasuo (Shizuoka, JP); Inagi; Toshio (Mishima, JP)
Assignee: Kowa Co., Ltd. (Nagoya, JP)
Appl. No.: 414008
Filed: April 16, 2003
Abstract
The invention provides a solid dispersion composition containing 2-benzyl-5-(4-chlorophenyl)-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one, hydroxypropylmethyl cellulose, and polyoxyethylene polyoxypropylene glycol. The solid dispersion composition of the present invention exhibits the excellent dissolvability of 2-benzyl-5-(4-chlorophenyl)-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one in water, and enables this compound to be constant sequentially and thereby improve absorbability in blood.