Rational Design of Stable Protein Formulations: Theory and Practice

Rational Design of Stable Protein Formulations: Theory and Practice
by John F Carpenter, Mark C Manning
Bibliographic information
Title Rational Design of Stable Protein Formulations
Author(s) John F Carpenter, Mark C Manning
Publisher Springer
Publication Date April 1, 2002
Subject Science
Format Hardcover
Pages 203
Dimensions 6.22 x 0.66 x 9.24 in
ISBN 0306467410
Book Description:
Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.