Photoinduced repair of a thymine dimer in DNA via carbazole nucleoside - DNA

Photoinduced repair of a thymine dimer in DNA via carbazole nucleoside
2006
Yoshinaga Yoshimura1,2 and Kenzo Fujimoto1,2
1 School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan, 2 PRESTO, Japan Science and Technology Agency
Nucleic Acids Symposium Series 2006
We report the photoinduced repair of a thymine dimer incorporated in a DNA duplex via oligodeoxynucleotide (ODN) containing carbazole nucleoside (K). The occurrence of an electron transfer between K and thymine dimer is evidenced by fluorescence quenching measurements. K acts as a good electron donor for the photoinduced repair of a thymine dimer.
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