Pharmaceutical composition for oral use with improved absorption - Patent Pending

United States Patent Application 20050112206
Kind Code A1
Watanabe, Shunsuke ; et al. May 26, 2005
Pharmaceutical composition for oral use with improved absorption
Abstract
The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least this polymer and this acidic substance, and a method of improving oral absorption/by using this pharmaceutical composition. Moreover, the present invention presents an agent for improving oral absorption that increases drug permeability of the digestive tract mucous membrane and/or mucous layer present on the surface of this membrane, whose active ingredient is aminoalkyl methacrylate copolymer E. In addition, the present invention presents an oral agent for improving absorption by increasing drug permeability of the digestive tract mucous membrane and/or the mucous layer distributed over this mucous membrane, whose effective component is aminoalkyl methacrylate copolymer E.
Inventors: Watanabe, Shunsuke; (Shizuoka, JP) ; Takemura, Shigeo; (Shizuoka, JP) ; Tsutsui, Yuuki; (Shizuoka, JP) ; Kondo, Himoru; (Shizuoka, JP) ; Nakanishi, Kiyo; (Shizuoka, JP) ; Sako, Kazuhiro; (Shizuoka, JP) ; Sawada, Toyohiro; (Shizuoka, JP)
Correspondence Name and Address: TOWNSEND AND TOWNSEND AND CREW, LLP
TWO EMBARCADERO CENTER
EIGHTH FLOOR
SAN FRANCISCO
CA
94111-3834
US
Assignee Name and Adress: Yamanouchi Pharmaceutical Co., Ltd.
Tokyo
JP
Serial No.: 949114
Series Code: 10
Filed: September 10, 2004
U.S. Current Class: 424/487
U.S. Class at Publication: 424/487
Intern'l Class: A61K 009/70; A61K 009/14