PHARMACEUTICAL COMPOSITIONS FOR NASAL DELIVERY

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Patent Number: WO2004075824
Publication date: 2004-09-10
Inventor(s): MERKUS FRANCISCUS W H (BE); LAMBERT PETER ALAN (GB); ADAMS GERALD (GB)
Applicant(s): BRITANNIA PHARMACEUTICALS LTD (GB); MERKUS FRANCISCUS W H (BE); LAMBERT PETER ALAN (GB); ADAMS GERALD (GB)
Requested Patent: WO2004075824
Application Number: WO2004GB00846 20040301
Priority Number(s): GB20030004636 20030228
IPC Classification: A61K
EC Classification: A61K9/00M14, A61K9/19, A61K31/48, A61K31/485
Equivalents:
Cited Documents: US5756483; US5578567
Abstract
According to the invention there is provided a powdered pharmaceutical formulation suitable for nasal delivery which is a freeze-dried blend of active material and excipient(s) containing: 0.5 - 50 % by wt of active material 50 - 99.5 % by wt of excipient(s), and in which at least 0.1 % by wt of the blend is an amorphous state, which can be directly obtained by freeze drying without the need for milling and without containing the pronounced low particles defined as finings. Such powders retain free-flowing properties on storage, are physically and chemically stable and are readily soluble.

Data supplied from the esp@cenet database - l2