PGE1-CONTAINING FREEZE-DRIED PREPARATION AND THE PRODUCTION THEREOF - Patent Pending

(12) Patent Application: (11) CA 2231682
ABSTRACT:
A preparation relating to a PGE1-containing fat emulsion with excellent qualities which is superior to the conventional ones bacteriologically or in thermal or prolonged stability. The preparation is a freeze-dried one derived from a fat emulsion which contains PGE1, an oily component, an emulsifier and water and has a liquid nature (pH value) within the neutral region. In other words, it is a PGE1-containing freeze-dried preparation characterized by containing PGE1, an oily component and an emulsifier and having a liquid nature (pH value) falling within the neutral region immediately after the reconstitution (restoration) with distilled water of pH 7?
(72) Inventors (Country): SEKI, JUNZO (Japan)
SASAKI, HIDEKI (Japan)
YOSHIKAWA, HIROFUMI (Japan)
(73) Owners (Country): NIPPON SHINYAKU CO., LTD. (Japan)
(71) Applicants (Country): NIPPON SHINYAKU CO., LTD. (Japan)
(74) Agent: FETHERSTONHAUGH & CO.
(45) Issued:
(86) PCT Filing Date: Sep. 12, 1996
(87) PCT Publication Date: Mar. 20, 1997
(51) International Class (IPC): A61K 9/19
A61K 31/557
Patent Cooperation Treaty (PCT): Yes (85) National Entry: Mar. 11, 1998
(86) PCT Filing number: PCT/JP1996/002611
(87) International publication number: WO1997/009986
(30) Application priority data: Application No. Country Date
HEI-7/235,588 Japan Sep. 13, 1995
Availability of licence: N/A
Language of filing: English