New particle engineering technology improves drug solubility

New particle engineering technology improves drug solubility
Haystead, John
1/1/2003
Pharmaceutical Technology
According to industry studies, more than 30% of new chemical entities developed during drug discovery efforts exhibit poor solubility characteristics, severely limiting their therapeutic usefulness. Today, however, recent advancements in particle engineering technology may be opening the door to a host of drug compounds previously considered unviable.
Because dissolution rates are related to surface area, one approach to increasing solubilization is to prepare drug particles of uniformly small size and high surface area. To take advantage of this, Dow Chemical Company ...
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