Murine genomic polynucleotide sequence encoding a G-protein coupled receptor and methods of use therefor
Murine genomic polynucleotide sequence encoding a G-protein coupled receptor and methods of use therefor
United States Patent 7,115,724
Pausch
October 3, 2006
Inventors: Pausch; Mark H. (Rocky Hill, NJ)
Assignee: Wyeth (Madison, NJ)
Appl. No.: 10/208,483
Filed: July 30, 2002
Abstract
The present invention particularly relates to a newly identified murine genomic polynucleotide that encodes an ortholog of the human P2T receptor which is expressed at high levels in the central nervous system, the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. The invention relates also to identifying compounds which may be agonists, antagonists and/or inhibitors of P2T, and therefore potentially useful in therapy.
Votes:34