Multi-functional container closure delivery system

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Multi-functional container closure delivery system
Inventor: CHANG BYEONG S (US); LIU ROGER W (US)
IPC: B67D5/60; B67D5/60
Publication info: US2006157507
Date: 2006-07-20
Abstract of US2006157507
A container closure delivery system that is suitable for lyophilized pharmaceutical injectable powder products is disclosed. The system comprises storage stable powder formulations and a container closure assembly design wherein the formulation can be filled and lyophilized with a standard fill finish equipment, and the formulations and lyophilization processes are optimized to produce a powder that readily dissolves upon contact with a diluent, thereby facilitating the direct injection of the lyophilized product without the need for a separate reconstitution/mixing/priming step. Importantly, the container closure assembly also provides for modularity of dosing, the ability to dose multiple products in a single dose, intranasal delivery, and multi-dosing.