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Sample enrichment techniques in capillary electrophoresis: Focus on peptides and proteins
Engineering Village 2
2006 Elsevier Inc.
Accession number: 063510091680

Title: Sample enrichment techniques in capillary electrophoresis: Focus on peptides and proteins

Authors: Monton, Maria Rowena N.; Terabe, Shigeru

Author affiliation: Graduate School of Material Science, University of Hyogo, Kamigori, Hyogo, 678-1297, Japan

Serial title: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Abbreviated serial title: J. Chromatogr. B Anal. Technol. Biomed. Life Sci.

Volume: v 841

Issue: n 1-2

Monograph title: Analysis of Proteins, Peptides and Glycanes by Capillary (Electromigration) Techniques

Issue date: Sep 1 2006

Publication year: 2006

Pages: p 88-95

Language: English

ISSN: 1570-0232

CODEN: JCBAAI

Document type: Journal article (JA)

Publisher: Elsevier, Amsterdam, 1000 AE, Netherlands

Abstract: Compared to chromatography-based techniques, the concentration limits of detection (CLOD) associated with capillary electrophoresis are worse, and these have largely precluded their use in many practical applications. To overcome this limitation, researchers from various disciplines have exerted tremendous efforts toward developing strategies for increasing the concentration sensitivities of capillary electrophoresis (CE) systems, via the so-called sample enrichment techniques. This review highlights selected developments and advances in this area as applied to the analyses of proteins and peptides in the last 5 years. ? 2006 Elsevier B.V. All rights reserved.

Number of references: 105

Ei main heading: Polypeptides

Ei controlled terms: Proteins - Electrophoresis - Electromigration - Biomedical engineering - Chromatographic analysis

Uncontrolled terms: Sample enrichment - Concentration sensitivity - Concentration limits of detection (CLOD)

Ei classification codes: 804.1 Organic Compounds - 815.1.1 Organic Polymers - 701.1 Electricity: Basic Concepts & Phenomena - 801.3 Colloid Chemistry - 801.4.1 Electrochemistry - 461.1 Biomedical Engineering

Treatment: Literature review (LIT); Theoretical (THR)

DOI: 10.1016/j.jchromb.2006.04.017

Database: Compendex

Compilation and indexing terms, ? 2006 Elsevier Inc. All rights reserved
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