Mitogenic oxygenases
Mitogenic oxygenases
United States Patent 7,045,351
Lambeth , et al.
May 16, 2006
Mitogenic oxygenases
Inventors: Lambeth; J. David (Decatur, GA); Griendling; Kathy K. (Stone Mountain, GA); Lassegue; Bernard P. (Decatur, GA); Arnold; Rebecca S. (Lilburn, GA); Cheng; Guangie (Lilburn, GA)
Assignee: Emory University (Atlanta, GA)
Appl. No.: 318906
Filed: December 13, 2002
Abstract
The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
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