Methods and compositions for combination RNAi therapeutics

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Methods and compositions for combination RNAi therapeutics
Publication number: AU2005213485
Publication date: 2005-08-25
Inventor: LI BAO-JIAN; LU PATRICK Y; XIE FRANK Y; WOODLE MARTIN C
Applicant: INTRADIGM CORP
Classification:
- international: C07H21/02; C07H21/00;
- european:
Application number: AU20050213485 20050207
Priority number(s): US20040541776P 20040205; WO2005US03858 20050207
Also published as:

WO2005076999 (A3)
WO2005076999 (A2)

Abstract not available for AU2005213485
Abstract of corresponding document: WO2005076999

Compositions and methods containing mixtures of siRNA molecules that target genes associated with disease are provided. The mixtures of siRNA molecules provide greater efficacy in reducing expression of disease-associated genes than individual siRNA molecules.