Method of preparing a freeze-dried formulation containing a drug - Patent Articles

United States Patent 5,044,091
Ueda , et al. September 3, 1991
Method of preparing a freeze-dried formulation containing a drug
Abstract
In a freeze-drying method for producing a dried pharmaceutical compound or preparation, a first liquid is frozen, a second liquid is added to the frozen first liquid and is frozen thereon, and the frozen first and second liquids are freeze-dried together, in which at least one of said first and second liquids contains said pharmaceutical compound of preparation dissolved or suspended therein. The other liquid or liquids may be pure solvent (generally water) or may contain one or more other substances.
Inventors: Ueda; Seigo (Shinagawa, JP); Hashi; Kunio (Shinagawa, JP); Shiokari; Takashi (Shinagawa, JP); Kusai; Akira (Shinagawa, JP)
Assignee: Sankyo Company, Limited (Tokyo, JP)
Appl. No.: 509967
Filed: April 16, 1990
Foreign Application Priority Data
Apr 18, 1989[JP] 1-98561
Current U.S. Class: 34/303; 34/92
Intern'l Class: F26B 005/06
Field of Search: 34/4,5,15,92