Method for lyophilizing an active agent

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Method for lyophilizing an active agent
United States Patent 6,907,679
Yarborough , et al.
June 21, 2005
Inventors: Yarborough; Cody L. (Ft. Collins, CO), Madril; Dominic G. (Loveland, CO), Bawa; Rajan (Ft. Collins, CO)
Assignee: QLT USA, Inc. (Fort Collins, CO)
Appl. No.: 10/391,480
Filed: March 17, 2003
Abstract
A process for lyophilizing a solution of an active agent in a container is provided. Solution of active agent is deposited into a container, the container is covered with a covering plate and placed inside a lyophilizing apparatus. Lyophilization can be conducted to dryness by radiation, convection or both. Also provided is a device made by this process, an active agent-plastic administration device (e.g., a syringe), containing an active agent in the form of lyophilized cake, and an array of such administration devices.