METHOD OF PACKAGING FREEZED DRIED VACCINES IN SYRINGES AND PLUG FOR IMPLEMENTING THE METHOD - Patent Articles

(12) Patent: (11) CA 2061204
ABSTRACT
In a method of packaging freeze dried vaccine in a bypass syringe (1) the sterilized syringes are disposed in rows in an aseptic dispensing machine. Doses (23) of the solution or suspension to be freeze dried are introduced into the syringes. A temporary plug (11) is inserted in the same machine into the mouth of the syringe body in a position allowing communication between the interior of the syringe body and the exterior. The syringes are introduced into a freeze drying machine.
The vaccine is freeze dried. At the end of the freeze drying cycle the temporary plug (11) is depressed in a controlled atmosphere in the tank of the freeze drying machine into a hermetic sealing position. The syringes
(1) are transferred into an aseptic dispensing machine.
The temporary plug (11) is removed. An intermediate piston-plug (9) is fitted. The Base (25) of solvent is introduced and an end piston-plug (10) is fitted.
72) Inventors (Country): GALY, MICHEL GERMAIN HENRY (France)
GOMEZ, ALAIN (France)
(73) Owners (Country): PASTEUR MERIEUX SERUMS ET VACCINS (France)
(71) Applicants (Country):
(74) Agent: FETHERSTONHAUGH & CO.
(45) Issued: July 2 , 2002
(22) Filed: Feb. 14, 1992
(41) Open to Public Inspection: Aug. 16, 1992
Examination requested: Feb. 12, 1999
(51) International Class (IPC): B65B 29/00
B67C 3/22
Patent Cooperation Treaty (PCT): No
(30) Application priority data: Application No. Country Date
91 01802 France Feb. 15, 1991
Availability of licence: N/A
Language of filing: English