METHOD OF EVALUATING RNAi ACTIVITY AND miRNA ACTIVITY

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METHOD OF EVALUATING RNAi ACTIVITY AND miRNA ACTIVITY
Publication number: EP1693450
Publication date: 2006-08-23
Inventor: NAITO YUKI (JP); TEI KUMIKO (JP); ZENNO SHUHEI (JP); SAIGO KAORU (JP)
Applicant: BIO THINK TANK CO LTD (JP)
Classification:
- international: C12N15/09; C12N15/11; C12Q1/68; G01N33/15; G01N33/50; C12N15/09; C12N15/11; C12Q1/68; G01N33/15; G01N33/50;
- european: C12N15/11M; C12Q1/68P
Application number: EP20040818954 20041118
Priority number(s): WO2004JP17182 20041118; JP20030392304 20031121

Also published as:

WO2005049821 (A1)

Abstract of EP1693450

The present invention provides methods whereby an RNAi activity and a miRNA activity can be evaluated simply and conveniently. The RNAi activity or the miRNA activity is evaluated by supplying a target-expressing molecule, which is a polynucleotide containing at least a target sequence and an expression regulatory region regulating the expression of an RNA containing the target sequence, and a subject nucleic acid molecule to be evaluated on whether or not it has RNAi activity on the RNA containing the target sequence into an expression system in which the target-expressing molecule can express the RNA containing the target sequence.