JOINT LYOPHILIZATION-MEDIATED FORMATION OF PEPTIDE-LIPID COMPLEX

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JOINT LYOPHILIZATION-MEDIATED FORMATION OF PEPTIDE-LIPID COMPLEX
Inventor: DASSEUX JEAN-LOUIS
EC: A61K9/127M; A61K9/127P
IPC: A61K9/19; A61K9/127; A61K38/00
Publication info: RU2224506
Date: 2004-02-27
Abstract of RU2224506
FIELD: pharmaceutical industry. SUBSTANCE: invention consists in that peptidelipid vesicles and complexes are formed via joint lyophilization of peptides, especially those capable of assuming amphipathic alpha-helical conformation, and one or more lipids. Peptides and lipids are initially dissolved to give common solution or two separate solutions. EFFECT: achieved stabilization of peptide-lipid vesicles and complexes. 61 cl, 8 dwg, 1 tbl, 2 ex