Drug Transporters and ADME Pharmacological and Commercial Implications - Market Research

Drug Transporters and ADME Pharmacological and Commercial Implications
By: Drug and Market Development Publishing
Price: $2,995.00
Publish Date: August 1, 2004
110 Pages
Pub ID: DSMD1092297
Drug transporters are key factors in absorption, distribution, metabolism, and excretion (ADME) of many new medicines. ADME models are increasingly influential in determining whether a New Chemical Entity (NCE) or biopharmaceutical should advance through R&D. Over the last 15 years, a heterogeneous group of proteins, collectively known as drug transporters, emerged as critical determinants of ADME for many drugs. Understanding drug transporters is critical to the analysis of a drug's pharmacokinetics and pharmacodynamics. Integrating an analysis of drug transporters is now a core competency in ADME assessments.
D&MD's Drug Transporters and ADME Report delineates some issues facing companies attempting to integrate the role of drug transporters in pharmacokinetics and pharmacodynamic assessment. The Report highlights strengths and weakness of the current means for assessing drug transporters and those areas where more research is needed. In addition, this Report summarizes the approaches companies are taking in order to better understand the role of drug transporters in ADME and provides in-depth interviews with several world-leading experts drawn from industry and academia.