DNA Microarrays: A Market Update

DNA Microarrays: A Market Update

Published Date: June 2006
Published By: Biocompare
Page Count: 55
Order Code: R711-25
Price: $2300 Online Download
$5750 Global Site License

DESCRIPTION

The 2006 DNA Microarray Report is composed of a market overview and an introduction to the 2006 DNA Microarray Survey, which contains questions about the DNA microarray systems and related applications that researchers are using. The report also includes a discussion of the survey results and conclusions and recommendations drawn from both the market analysis of DNA microarrays and the survey data. In addition, a new feature, industry dialog, presents an interview with an expert in DNA microarrays and rounds out this comprehensive report offering.
The market overview describes the use of DNA microarrays in the life science research arena to examine gene expression and single nucleotide polymorphisms (SNPs), as well as to characterize entire genomes. DNA microarrays have also found applications in drug discovery, including lead compound optimization, toxicity studies, and the screening and monitoring of patient data during clinical trials.
The first report of the use of DNA microarrays came in 1991, with the publication of the chemical synthesis of oligonucleotides on glass chips by Fodor et al.1 This author went on to develop the first DNA microarray and founded the company Affymetrix, still the major industry leader of microarrays and associated reagents today. Currently, Affymetrix brings in well over $350 million in microarray-related revenue annually. Other companies have since joined in the hunt for market share, including Agilent, GE Healthcare, and Illumina. But at present, these three companies combined only account for just over one-third of Affymetrix?s microarray sales.
Custom arrays are becoming more popular among scientists and have brought other companies into the microarray arena. NimbleGen joined with Affymetrix to provide a flexible photolithographic Maskless Array technology, which is advantageous for the production of custom arrays. Invitrogen acquired Xeotron Corp, a producer of custom arrays, to make forays into the microarray market. DNA microarrays currently bring in yearly revenues of nearly $450 million, growing at almost 11% annually. Microarray scanners and readers also contribute to this figure, with a compound annual growth rate that is predicted to approach almost $1 billion by 2010.
The advances in various technologies have spurred interest in DNA microarrays and their applications. Better instrumentation, higher throughput, and lower cost continue to draw more users from a variety of scientific disciplines. The expanding use of nucleic acid microarrays has provided a needed boost for clinical diagnostics, biodefense, forensics, and agriculture, areas outside the traditional domain of the life sciences. Advances in biochips, a chip assay format, are predicted to boost microarray revenues even higher, with an average annual growth rate predicted to top $5.3 billion by 2009. Such anticipated growth will open the door for other innovative companies to share in the market.
Survey Introduction
The 2006 DNA Microarray Survey is designed to provide vendors of DNA microarray systems with a better understanding of how their products are used in the research environment and how their company rates among survey participants. Data were gathered from questions regarding how often nucleic acid microarrays are used in the survey participant?s research, their goals and applications for nucleic acid microarrays, the current microarray facility that is used, the major commercial vendors that come to mind in relation to DNA microarrays, the organisms studied using arrays, how many microarrays are hybridized per week and if that number is expected to change, the specific brands of microarray reagents that are used, the types of dyes and arrays that are used, unmet needs for custom array production, challenges to the use of pre-spotted arrays, plans to use miRNA arrays, what equipment is used to process microarrays, descriptions of scanners and commonly used scanner resolution, descriptions of the microarray analysis software, future purchasing plans, and the attributes that might cause one to switch to a new microarray platform.
Survey Methodology
The 2006 DNA Microarray Survey consisted of 30 questions. Of these, 20 included ?other? as an answer choice and 2 were open-ended. Four questions were used for demographic information. The survey was administered on-line from May 1st-11th, 2006, and the data gathered, tabulated, and presented here.
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