Cardinal Health - R&D Services

Cardinal Health (New Jersey)
14 Schoolhouse Road
Somerset, New Jersey 08873 U.S.A.
Phone: 732-537-6200
Toll Free: 866-720-3148
Fax: 732-537-5949
E-Mail: pdinfo@cardinal.com
Manufacturing:
Sterile Products - Lyophilization
Since its commercialization in World War II as a method for preserving blood plasma and penicillin for use on the battlefront, lyophilization has become an increasingly widespread practice to stabilize process sensitive pharmaceuticals.
Our depth of experience in lyophilization, especially with process sensitive biotechnology products, ensures product success. Advanced cycle development and process validation skills, coupled with scale up procedures that are integrated between our commercial and clinical teams, make Cardinal Health an industry leader in both quality and manufacturing capacity.
Today, Cardinal Health offers a range of sterile lyophilization techniques in a cGMP-compliant environment, including:
Nitrogen back filling
Vacuum control
Primary and secondary ramp/soak
Mechanical stoppering under various pressures
T-Butanol
"At Cardinal Health we operate eight lyophilizers at three of our seven sterile contract manufacturing facilities. Duplicate capacity at these facilities gives us the ability to schedule your project for maximum efficiency and flexibility."
Profile
Cardinal Health is the global leader in product development, drug delivery technologies, contract manufacturing, packaging and healthcare marketing services, serving the global pharmaceutical and biotechnology industry. With a proven track record of global expertise and innovation, Cardinal Health brings its customers innovative expertise throughout a drug's development, launch and entire life cycle. And Cardinal Health offers the broadest range of dose form development and manufacturing options in the industry-from traditional and proprietary oral forms to sterile products, inhaled forms and topicals-in more than 40 facilities on five continents.
Development:
Cardinal Health offers a full range of drug development services, such as discovery support, synthesis, pharmaceutics, analytical chemistry, microbiology, structural chemistry, clinical manufacturing and clinical supply services, as well as product development for both small and large molecules. We also have expertise in inhalation and radiopharmaceutical product development, and can offer innovative cell-line development using our proprietary GPEx? technology.
Drug Delivery:
Cardinal Health holds more than 1,000 patents and patent applications for drug delivery systems. Our drug delivery technologies include soft gelatin capsules, Zydis? fast dissolve dosage form; EnCirc?, EnVel?, EnGel? and EnSolv(tm) for oral modified release products; lyophilization; sterile liposomes; inhaled technologies (MDI, DPI, nasal sprays); and topical Microsponge? for timed release and DelPouch? for unit dosing.
Manufacturing:
We provide manufacturing for nearly every dose form on the market today. Along with our proprietary dose forms, we also manufacture traditional oral dose forms (tablets, capsules,liquids), sterile dose forms (lyophilization, fill/finish manufacture in vials, ampoules, prefilled syringes, and our innovative "Blow/Fill/Seal" aseptic technology), and topical and inhaled forms. We also produce biologics for pre-clinical and clinical studies, and both clinical and commercial radiopharmaceuticals. We can also help improve yields in commercial biologics production using our proprietary GPEx? technology.
Packaging:
Cardinal Health helps pharmaceutical and biotech companies build strong brand franchises by designing unique packaging solutions that create shelf presence and improve patient compliance. From cartons to promotional materials to printed inserts and labels, we offer expertise and attention to detail.
Launch:
Cardinal Health offers a full range of product launch and marketing services including medical education, promotional education, patient education, contract sales and services. We can also provide product and service logistics, distribution support, sample and literature fulfillment and reimbursement support.
Post-Launch:
New dosage forms, line extensions, or proprietary delivery technologies and customized marketing, sales and medical education from Cardinal Health can extend a product's life cycle and maximize its profitability.