BIOLOGICAL MATERIAL AND METHODS AND SOLUTIONS FOR PRESERVATION THEREOF

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BIOLOGICAL MATERIAL AND METHODS AND SOLUTIONS FOR PRESERVATION THEREOF
Publication Number: WO/2005/072523 International Application No.: PCT/IL2005/000125
Publication Date: 11.08.2005 International Filing Date: 02.02.2005

Int. Class.: A01N 1/02 (2006.01)
Applicants: I.M.T. INTERFACE MULTIGRAD TECHNOLOGY LTD. [IL/IL]; 3 Hamazmera Street, P.O.B. 2044, 70400 Ness Ziona (IL) (All Except US).
NATAN, Yehudit [IL/IL]; 10 Urim Street, 58307 Holon (IL) (US Only).
KANIAS, Tamir [IL/IL]; 8/8 Zevulun Hammer Street, 54423 Givat Shmuel (IL) (US Only).
Inventors: NATAN, Yehudit [IL/IL]; 10 Urim Street, 58307 Holon (IL).
KANIAS, Tamir [IL/IL]; 8/8 Zevulun Hammer Street, 54423 Givat Shmuel (IL).
Agent: REINHOLD COHN AND PARTNERS; P.O.Box 4060, 61040 Tel Aviv (IL).
Priority Data: 60/540,557 02.02.2004 US
60/577,210 07.06.2004 US

Abstract: The invention provides a preservation solution for preserving biological material at low temperature comprising one or more polyphenols and a method for preservation of biological material, said method comprising adding the preservation solution to biological material, cooling the biological material and storing it at appropriate storing conditions. The method of the present invention may be used for hypothermic preservation or for cryopreservation, including freezing and lyophilization, and may be used with any biological material, including cells selected from RBC, WBC, MNC, UCB MNC and bacteria. In case of RBC the present invention also disclosed a method for its freezing such that upon thawing, the material has less than 2% free hemoglobin.