Administration of antibody to the lung protects mice against pneumonic plague

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Administration of antibody to the lung protects mice against pneumonic plague
2006 May
Hill J, Eyles JE, Elvin SJ, Healey GD, Lukaszewski RA, Titball RW.
Infect Immun.
Intratracheal delivery of aerosolized monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a model of pneumonic plague. These data support the utility of inhaled antibodies as a fast-acting postexposure treatment for plague.
PMID: 16622253 [PubMed - indexed for MEDLINE]