AAPS/China Pharmaceutical Association Joint Symposium on Current Status and Future Trends in Drug Delivery System Aug 29-31, 2005 China
AAPS/China Pharmaceutical Association Joint Symposium on Current Status and Future Trends in Drug Delivery System
Aug 29-31, 2005
Shenyang Pharmaceutical University
Shenyang, China
Drug delivery systems for poorly water soluble compound, sustained release system and biopharmaceuticals, such as peptide and proteins are an integral part of pharmaceutical product development. Enhancing the oral absorption of poorly soluble drugs and/or controlling/extending drug absorption for compounds with short half-lives can usually be achieved by drug delivery system. Physical pharmaceutics and preformulation are very important when poorly water soluble compounds are of interest; Material science and various types of controlled release systems that could overcome physiological limitations such as food effect, the development of IVIVC are very important when controlled release dosage form are of interest; Stability (pH, enzymatic), permeability and delivery options are very important when protein and peptide delivery is of interest.
This program will address both fundamental and practical aspects of formulating drug candidates requiring improved oral absorption or controlled release, as well as process design, development and scale-up. Specific topics to be covered include:
(1) Insoluble Drugs: Basic physical pharmaceutics principles; Characterization and evaluation of drug properties and dosage form design; Impact of drug characteristics on formulation and process development of solid dosage forms. Case studies of special drug delivery system for poorly water-soluble compounds.
(2) Controlled Release Systems: Design and development of different types of oral controlled release dosage form; Case studies of controlled release dosage form based on different principles and development and validation of in vitro-in vivo correlation (IVIVC).
(3) Delivery of Biopharmaceuticals: Past, current and future of protein and peptide delivery, including oral delivery. Case studies of current available approaches for protein and peptide delivery.
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