2005 Colorado Protein Stability Conference - July 14-16, 2005 - Breckenridge, Colorado

2005 Colorado Protein Stability Conference
July 14-16, 2005 - Breckenridge, Colorado
Village at Breckenridge
MEETING DESCRIPTION
Protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all of the relevant areas can join together to discuss the critical issues in the field. The 2005 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include: prediction and manipulation of pathways for protein folding, aggregation; protein-solute interactions; and development of stable formulations.
The scientific sessions will consist of plenary lectures by leading researchers. In addition, contributed papers will be presented during a poster session. To foster exchange of information, the meeting will be limited to 200 registrants, and there will be ample opportunity for informal discussions.
The meeting will begin with a reception on Wednesday (7/13) evening. The scientific sessions will start on Thursday. The poster session will be held on Friday morning. The Conference will close with a reception on Saturday evening.
SCIENTIFIC PROGRAM
7/14 Folding and Stability
George Rose, Johns Hopkins Univ
Proteins: The Unfolding Story
George Makhatadze, Penn State Univ
Engineering Proteins for Thermostability
Dan Raleigh, SUNY-Stony Brook
What about U? The Role of the Unfolded State in Protein Stability & Protein Folding
Cecilia Clementi, Rice University
Optimal Combination of Theory & Experiment to Explore the Protein Folding Landscape
Nick Pace, Texas A&M Univ.
Probing the Denatured State with Fluorescence
Peter Wolynes, Univ. of Calif.-San Diego,
TBA
Paula Booth, Univ. of Bristol
The Lipid Environment can Modulate the Folding & Stability of Integral Membrane Proteins
John Carra, USAMIID
Conformational Changes of the Ricin A-Chain & an Improved Vaccine
Gary Pielak, Univ. of North Carolina
Protein NMR in Living E. coli Cells
7/14 Protein-Solute Interactions
Allen Minton, NIH
The Effect of ?Inert' Macromolecular Cosolutes on the Stability of Proteins: New Models & New Data
Jeff Carbeck, Princeton Univ.
Capillary electrophoresis to measure effects of solutes on protein stability
Bill Wilson, Mississippi State Univ.
High Throughput Approaches for Measuring Protein-Protein Interactions
7/15 Poster Session
7/16 Protein Aggregation
Carolyn Teschke, Univ. of Connecticut
Control of Nucleation of Viral Capsid Assembly
Chris Roberts, Univ. of Delaware
Manipulating, Measuring, & Understanding Aggregation Kinetics in Solution
Bernhardt Trout, MIT
Molecular Computational Engineering: Rational Design of Additives for Hindering Aggregation
Steve Shire, Genentech
Application of Sedimentation Analysis of Protein Biopharmaceutical Degradation Products
7/16 Formulation Development
Gerhard Winter, University of Munich
Application of Specific Analytical Methods for Development of Complex Protein Formulations
Marc Cicerone, NIST
Fast, Local Dynamics and Their Relevance to Protein Stability in the Glass
Jon Webb, Eli Lilly
Kinetics of Deamidation and Covalent Dimer Formation of Human Insulins in Acidic Solutions
Liz Topp, Univ. of Kansas
Effect of Secondary Structure on Deamidation in Solution and in the Solid State
Nick Warne, Wyeth
Influence of Delivery Matrix on BMP-2
Gautam Sanyal, AstraZeneca
Recombinant Protein Based Vaccine Formulations in Particulate Delivery Systems
Bruce Kerwin, Amgen
New Insight into the Effect of Formulation on Epoetin Structure