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Lyophilization and Protein Formulation
RNA - Protein Synthesis

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Bacterial delivery of functional messenger RNA to mammalian cells

Votes:8 Comments:0
Bacterial delivery of functional messenger RNA to mammalian cells May 2005 Christoph Schoen, Annette Kolb-M?urer, Gernot Geginat, et. Cell Microbiol The limited access to the nuclear compartme READ MORE
http://www.medscape.com/medline/abstract/15839900...

RNA delivery by heat shock protein-70 into mammalian cells: A preliminary study

Votes:22 Comments:0
RNA delivery by heat shock protein-70 into mammalian cells: A preliminary study May 2006 Tam?s Henics Cell Biol Int Heat shock proteins (Hsps) are ubiquitous molecular chaperones with indispen READ MORE
http://www.medscape.com/medline/abstract/16563814...

Cooperative binding and self-assembling behavior of cationic low molecular-weigh...

Votes:17 Comments:0
Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules Feb 2006 Jiehua Zhou, Jiangyu Wu, Xiaoxuan Liu, et. al. Org Biomol Chem Tri(ethylene READ MORE
http://www.medscape.com/medline/abstract/16446818...

Specific delivery of therapeutic RNAs to cancer cells via the dimerization mecha...

Votes:30 Comments:0
Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA Sep 2005 Songchuan Guo, Nuska Tschammer, Sulma Mohammed Hum Gene Ther The application READ MORE
http://www.medscape.com/medline/abstract/16149908...

Development of methods for RNA interference in the sheep gastrointestinal parasi...

Votes:25 Comments:0
Development of methods for RNA interference in the sheep gastrointestinal parasite, Trichostrongylus colubriformis Aug 2005 Z Issa, W N Grant, S Stasiuk Int J Parasitol The efficiency of RNA READ MORE
http://www.medscape.com/medline/abstract/16023650...

Vector-based in vivo RNA interference: dose- and time-dependent suppression of t...

Votes:20 Comments:0
Vector-based in vivo RNA interference: dose- and time-dependent suppression of transgene expression Feb 2004 Naoki Kobayashi, Yumi Matsui, Atsushi Kawase, et. J Pharmacol Exp Ther RNA interfere READ MORE
http://www.medscape.com/medline/abstract/14610223...

Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 R...

Votes:33 Comments:0
Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 RNA in breast milk and on postnatal transmission Oct 2004 Olivier Manigart, Montcho Crepin, Valeriane Leroy, et. al. READ MORE
http://www.medscape.com/medline/abstract/15378434...

Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseu...

Votes:28 Comments:0
Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions Sep 2005 Chava Kimchi-Sarfaty, Scott Brittain, Susan Garfield, et. al. Hum Gene Ther Previously we hav READ MORE
http://www.medscape.com/medline/abstract/16149909...

RNA interference in immune cells by use of osmotic delivery of siRNA

Votes:3 Comments:0
RNA interference in immune cells by use of osmotic delivery of siRNA Mar 2006 Mikio Aoki, Takayuki Ishii, Masaharu Biochem Biophys Res Commun Delivery of siRNA to immune cells has been one of READ MORE
http://www.medscape.com/medline/abstract/16426577...

University Of Pennsylvania Researchers Find Role For MicroRNAs In Oxygenation, N...

Votes:24 Comments:0
University Of Pennsylvania Researchers Find Role For MicroRNAs In Oxygenation, Nourishing Of Colon Tumors 8/1/2006 Bioresearch Online Philadelphia - Researchers from the University of Pennsylvani READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Purdue Scientists Treat Cancer With RNA Nanotechnology

Votes:4 Comments:0
Purdue Scientists Treat Cancer With RNA Nanotechnology 9/15/2005 Bioresearch Online West Lafayette, IN ? Using strands of genetic material, Purdue University scientists have constructed tiny del READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Tandem Transcripts Team Together

Votes:26 Comments:0
Tandem Transcripts Team Together 1/6/2006 Bioresearch Online In the January issue of the journal Genome Research, two teams of scientists describe a widespread phenomenon in the human genome READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Twin Molecular Scissors Link Creation Of MicroRNAs With Gene-Silencing

Votes:21 Comments:0
Twin Molecular Scissors Link Creation Of MicroRNAs With Gene-Silencing 11/4/2005 Bioresearch Online New insights into vital genome regulation strategy provided Philadelphia ? One of the body READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Activation Of MicroRNA Inhibits Cancer Gene In Human Cancer Cells

Votes:32 Comments:0
Activation Of MicroRNA Inhibits Cancer Gene In Human Cancer Cells 6/13/2006 Bioresearch Online Scientists report that tumor cells display a dramatic reduction of cancer-causing genes when a n READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial r...

Votes:17 Comments:0
Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice 2005 Rodriguez-Lebron E; Denovan-Wright READ MORE
http://www.medscape.com/medline/abstract/16019264...

Treating Cancer with RNA Nanotechnology

Votes:30 Comments:0
Treating Cancer with RNA Nanotechnology 9/15/05 Elizabeth Tolchin Advantage Business Media Using RNA nanotechnology researchers say they constructed delivery vehicles that can carry anticancer READ MORE
http://www.genpromag.com/ShowPR~PUBCODE~018~ACCT~1800000100~ISSUE~0509...

Lessons from Nature: microRNA-based shRNA libraries

Votes:14 Comments:0
Lessons from Nature: microRNA-based shRNA libraries 2006 Sep Chang K, Elledge SJ, Hannon GJ. Nat Methods. Loss-of-function genetics has proven essential for interrogating the functions of gene READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy ...

Votes:22 Comments:0
Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides 2006 Aug 4 Xu Q, Katkevica D, Rozners E. J Org Chem. Chemical reaction: see text] Recent discovery READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

More Effective RNA-Based Drugs

Votes:36 Comments:0
More Effective RNA-Based Drugs 2006 By Katherine Bourzac MIT Technology Review The ability to shut downspecific disease-causing genes could be a powerful weapon against cancer and infections suc READ MORE
http://www.technologyreview.com/printer_friendly_article.aspx...

TOPIGEN Begins IND-Enabling Studies for TPI-1100 the First RNA-Targeting Compoun...

Votes:22 Comments:0
TOPIGEN Begins IND-Enabling Studies for TPI-1100 the First RNA-Targeting Compound to Treat COPD 9/18/2006 GEN TOPIGEN Pharmaceuticals Inc., an emerging biopharmaceutical company specializing in READ MORE
http://www.genengnews.com/news/bnitem.aspx...

Small RNA?s Move into the Spotlight

Votes:26 Comments:0
Small RNA?s Move into the Spotlight 11 Oct 2005 By Jessica Shah Historically, biological research worldwide has focused primarily on genes, the functional sections of deoxyribonucleic acid (DNA) READ MORE
http://www.frost.com/prod/servlet/market-insight-top.pag...

New delivery technology paves way for disease therapies

Votes:39 Comments:0
New delivery technology paves way for disease therapies May 26, 2005 Harvard College A new way to administer therapeutic RNA molecules that efficiently guides them to cells throughout the body READ MORE
http://www.news.harvard.edu/gazette/2005/05.26/17-tumor.html

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alv...

Votes:34 Comments:0
Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice July 2, 2004 Donald Massaro, Gloria DeCarlo Massaro, and Linda Biadasz Clerch Am J Physiol Lung Cell M READ MORE
http://ajplung.physiology.org/cgi/content/abstract/287/5/L1066

EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Bre...

Votes:28 Comments:0
EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice JANUARY 2006 Alexei Shir1, Manfred Ogris2, Ernst Wagner2, Alexander L READ MORE
http://medicine.plosjournals.org/perlserv...

CRE recombinase-inducible RNA interference mediated by lentiviral vectors

Votes:4 Comments:0
CRE recombinase-inducible RNA interference mediated by lentiviral vectors 2004-05-11 Recently, several systems designed to trigger RNA interference by using small hairpin RNA driven by polymerase READ MORE
http://www.ihop-net.org/UniPub/iHOP/pm/10279849.html...

Nanoparticles Improve Antisense Delivery and Expression

Votes:37 Comments:0
Nanoparticles Improve Antisense Delivery and Expression May 22, 2006 NCI In the fight against cancer, antisense drugs that could block cancer genes from producing malicious proteins have the pote READ MORE
http://nano.cancer.gov/news_center/nanotech_news_2006-05-22a.asp

Silencing RNA: a novel treatment for pancreatic cancer?

Votes:7 Comments:0
Silencing RNA: a novel treatment for pancreatic cancer? 2005 N R Lemoine BMJ Publishing Group Ltd & British Society of Gastroenterology The antiapoptotic gene Bcl-2 has been a target for downre READ MORE
http://gut.bmjjournals.com/cgi/content/full/54/9/1215

The Structure of a Rigorously Conserved RNA Element within the SARS Virus Genome

Votes:20 Comments:0
The Structure of a Rigorously Conserved RNA Element within the SARS Virus Genome January 2005 Michael P. Robertson1,2, Haller Igel1,3, Robert Baertsch1,4, David Haussler1,4, Manuel Ares1,3, Willia READ MORE
http://biology.plosjournals.org/perlserv/...

Vaccination with messenger RNA

Votes:26 Comments:0
Vaccination with messenger RNA 2006 Pascolo S. Methods Mol Med. As an alternative to DNA-based vaccines, messenger RNA (mRNA)-based vaccines present additional safety features: no persistence, n READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Increasing Resistance of Tubular Epithelial Cells to Apoptosis by shRNA Therapy ...

Votes:40 Comments:0
Increasing Resistance of Tubular Epithelial Cells to Apoptosis by shRNA Therapy Ameliorates Renal Ischemia-Reperfusion Injury 2006 Oct Du C, Wang S, Diao H, Guan Q, Zhong R, Jevnikar AM. Am J Tra READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Gene silencing in the development of personalized cancer treatment: the targets,...

Votes:37 Comments:0
Gene silencing in the development of personalized cancer treatment: the targets, the agents and the delivery systems 2006 Aug Verreault M, Webb MS, Ramsay EC, Bally MB. Curr Gene Ther. The adven READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Therapeutic potential of RNA interference for neurological disorders

Votes:26 Comments:0
Therapeutic potential of RNA interference for neurological disorders Received 21 March 2006; accepted 2 June 2006. Available online 15 June 2006. Dinah W.Y. Saha Life Sciences Volume 79, Iss READ MORE
http://www.sciencedirect.com/science...

RNAi tackles a sexually transmitted disease

Votes:6 Comments:0
RNAi tackles a sexually transmitted disease 2006 Patricia Cristofaro & Bharat Ramratnam Nature Biotechnology Herpes simplex virus-2 (HSV-2) infection has reached epidemic proportions, with serop READ MORE
http://www.nature.com/nbt/journal/v24/n1/full/nbt0106-48.html

Hairpins for Switches: Artificial RNA ligands differentiate between on and off s...

Votes:28 Comments:0
Hairpins for Switches: Artificial RNA ligands differentiate between on and off states of riboswitches December 8, 2006 Physorg.com How does an organism know when it must produce a protein and in READ MORE
http://science.physorg.com/news84796252.html

NuGEN launches Ovation whole blood solution and RNA amplification system

Votes:22 Comments:0
NuGEN launches Ovation whole blood solution and RNA amplification system 7 December 2006 Medical Technology Business Europe SAN CARLOS, Calif.--(BUSINESS WIRE)--NuGEN, Technologies, Inc., has ann READ MORE
How does an organism know when it must produce a protein and in what a...

Peering into the shadow world of RNA

Votes:36 Comments:0
Peering into the shadow world of RNA December 4, 2006 SpiritIndia.com The popular view is that DNA and genes control everything of importance in biology. The genome rules all of life, it is thoug READ MORE
http://www.spiritindia.com/health-care-news-articles-4453.html

RNA Silencing Sheds Light on the RNA World

Votes:30 Comments:0
RNA Silencing Sheds Light on the RNA World December 5, 2006 Dr. Priya Saxena RxPG News RNA silencing ? also known as RNA interference ? is an intriguing phenomenon in which short, double-strande READ MORE
http://www.rxpgnews.com/genetics/RNA-Silencing-Sheds-Light-on-the-RNA-...

University emerges as important center for small RNA research

Votes:25 Comments:0
University emerges as important center for small RNA research Dec. 6, 2006 University of Delaware The University of Delaware is emerging as an important center for research on small ribonucleic a READ MORE
http://www.udel.edu/PR/UDaily/2007/dec/rna120606.html

Brain :: RNA map provides first comprehensive understanding of alternative splic...

Votes:3 Comments:0
Brain :: RNA map provides first comprehensive understanding of alternative splicing November 9, 2006 SpiritIndia.com new RNA map, created by a team of researchers at Rockefeller University and t READ MORE
http://www.spiritindia.com/health-care-news-articles-3550.html

The interaction networks of structured RNAs

Votes:22 Comments:0
The interaction networks of structured RNAs October 25, 2006 A. Lescoute and E. Westhof Nucleic Acids Research All pairwise interactions occurring between bases which could be detected in three- READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6587

Amino acid residue doublet propensity in the protein?RNA interface and its appli...

Votes:17 Comments:0
Amino acid residue doublet propensity in the protein?RNA interface and its application to RNA interface prediction November 27, 2006 Oanh T. P. Kim1, Kei Yura1,2,3,* and Nobuhiro Go2 1 Quantum B READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6450

Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor pro...

Votes:39 Comments:0
Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells December 1, 2006 Ross J. Molinaro READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6684

Cellular delivery of small interfering RNA by a non-covalently attached cell-pen...

Votes:15 Comments:0
Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: quantitative analysis of uptake and biological effect November 28, 2006 Sandra Veldhoen, Sandra D. READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6561

The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA...

Votes:28 Comments:0
The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing November 28, 2006 Kathryn S. Sciabica and Klemens J. Hertel* Department of Microbiology and Molecular Ge READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6612

Sequence-dependent gating of an ion channel by DNA hairpin molecules

Votes:4 Comments:0
Sequence-dependent gating of an ion channel by DNA hairpin molecules November 27, 2006 Veronica S. DeGuzman1,2, Clarence C. Lee3, David W. Deamer4 and Wenonah A. Vercoutere5,* 1 Ames Associate, READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6425

Sequence-dependent formation of intrastrand crosslink products from the UVB irra...

Votes:37 Comments:0
Sequence-dependent formation of intrastrand crosslink products from the UVB irradiation of duplex DNA containing a 5-bromo-2'-deoxyuridine or 5-bromo-2'-deoxycytidine November 27, 2006 Yu Zeng an READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6521

Chemical synthesis of RNA including 5-taurinomethyluridine

Votes:15 Comments:0
Chemical synthesis of RNA including 5-taurinomethyluridine 2006 Toshihiko Ogata and Takeshi Wada Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The Universitiy of T READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/9

A novel RNA synthetic method with a 2'-O-(2-cyanoethoxymethyl) protecting group

Votes:29 Comments:0
A novel RNA synthetic method with a 2'-O-(2-cyanoethoxymethyl) protecting group 2006 Yoshinobu Shiba, Hidetoshi Kitagawa, Yutaka Masutomi, Kouichi Ishiyama, Tadaaki Ohgi and Junichi Yano Discove READ MORE
http://nass.oxfordjournals.org/cgi/content/abstract/50/1/11

Flexizyme as a versatile tRNA acylation catalyst and the application for transla...

Votes:15 Comments:0
Flexizyme as a versatile tRNA acylation catalyst and the application for translation 2006 Hiroshi Murakami1, Atushi Ohta2, Yuki Goto1, Yusuke Sako2 and Hiroaki Suga1,2 1 Research Center for Adva READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/35

Kinetic analysis of ribosome binding process onto mRNA using a quartz-crystal mi...

Votes:10 Comments:0
Kinetic analysis of ribosome binding process onto mRNA using a quartz-crystal microbalance 2006 Shuntaro Takahashi1, Ryoko Akita1, Hiroyuki Furusawa1, Yoshihiro Shimizu2, Takuya Ueda2 and Yoshio O READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/49

High-throughput method for the prediction of low-resolution, three-dimensional R...

Votes:35 Comments:0
High-throughput method for the prediction of low-resolution, three-dimensional RNA structures 2006 Mariusz Popenda, ukasz Bielecki and Ryszard W. Adamiak Laboratory of Structural Chemistry of Nu READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/67

RNA recognition and recognition control of -peptide ribonucleic acids containing...

Votes:32 Comments:0
RNA recognition and recognition control of -peptide ribonucleic acids containing arginine residue by external factors 2006 Takehiko Wada1,2, Yoshiki Maeda1, Nobuya Sawa1, Hirofumi Sato2, Shiroh Fu READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/75

Identification of antisense RNA stem-loops that inhibit RNA-protein interactions...

Votes:8 Comments:0
Identification of antisense RNA stem-loops that inhibit RNA-protein interactions using a bacterial reporter system 2006 Akiko Yano, Mayumi Kunimoto, Takako Minami and Kazuo Harada Department of READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/77

HIV gene therapy using RNA virus systems

Votes:40 Comments:0
HIV gene therapy using RNA virus systems 2006 Masaaki Hayafune1, Naoko Miyano-Kurosaki1,2, Akiko Kusunoki1, Yuka Mouri1 and Hiroshi Takaku1,2 1 Department of Life and Environmental Science, Chib READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/79

An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA...

Votes:22 Comments:0
An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis mediated by RNase L 2006 Tomoharu Naito1, Tatsushi Yokogawa1, Hye-Sook Kim1, Akira Matsuda2, Takuma Sasak READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/103
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