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Lyophilization and Protein Formulation
Oligonucleotides - Protein Synthesis

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Stabilization of oligonucleotide?polyethylenimine complexes by freeze-drying: ph...
Votes:7 Comments:0
Stabilization of oligonucleotide?polyethylenimine complexes by freeze-drying: physicochemical and biological characterization February 2004 By Carola Brus , Elke Kleemann , Achim Aigner , Frank Czub READ MORE
http://www.sciencedirect.com/science...

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition a...
Votes:18 Comments:0
Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides Published online 7 January 200 READ MORE
http://nar.oupjournals.org/cgi/content/full/33/1/27...

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-dea...
Votes:17 Comments:0
Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists Ekambar R. Kandimalla *, Lakshmi Bhagat *, Yukui Li *, Dong READ MORE
http://www.pnas.org/cgi/content/abstract/102/19/6925...

A peptide carrier for the delivery of biologically active proteins into mammalia...
Votes:30 Comments:0
Most notably, the presence of Pep-1 did not alter the enzymatic activity of beta-Gal upon delivery into cells. Finally, efficient transfection of beta-Gal was equally observed when transfection was pe READ MORE
http://www.nature.com/nbt/journal/v19/n12/full/nbt1201-1173.html

Oligonucleotide Therapeutics: A Step Forward
Votes:6 Comments:0
Given these facts, one might ask why this work5 is worthy of comment. First, the study involves a reasonable number of patients, and important pharmacokinetic data, including correlation of response w READ MORE
http://www.jco.org/cgi/content/full/18/9/1809

Discovery of new human retrovirus
Votes:25 Comments:0
DeRisi observed that "it may be that men who are so-called RNASEL-mutant are just more susceptible to viruses in general, and this susceptibility has little to do with their cancer. Nevertheless, the READ MORE
http://www.news-medical.net/...

Conjugation of ?-Fe2O3 nanoparticles with single strand oligonucleotides
Votes:28 Comments:0
Conjugation of ?-Fe2O3 nanoparticles with single strand oligonucleotides Available online 3 March 2006. C.W. Leea, K.T. Huangb, P.K. Weia and Y.D. Yaob, , Journal of Magnetism and Magnetic Mat READ MORE
http://www.sciencedirect.com/science...

Solid-phase chemical tools for glycobiology
Votes:4 Comments:0
Solid-phase chemical tools for glycobiology Received 17 February 2006; revised 25 April 2006; accepted 28 April 2006. Available online 22 May 2006. Kim Larsena, Mikkel B. Thygesena, Fanny Guil READ MORE
http://www.sciencedirect.com/science...

A Bacterial Reporter System for the Evaluation of Antisense Oligodeoxynucleotide...
Votes:37 Comments:0
A Bacterial Reporter System for the Evaluation of Antisense Oligodeoxynucleotides Directed against Human Papillomavirus Type 16 (HPV-16) Received 1 August 2005; accepted 21 November 2005. (ARCMED READ MORE
http://www.sciencedirect.com/science...

Bicontinuous Cubic Phase of Monoolein and Water as Medium for Electrophoresis of...
Votes:31 Comments:0
Bicontinuous Cubic Phase of Monoolein and Water as Medium for Electrophoresis of Both Membrane-Bound Probes and DNA Received July 29, 2005 In Final Form: January 26, 2006 Web Release Date: March READ MORE
http://pubs.acs.org/cgi-bin/article.cgi/langd5/2006/22/i09/html/la0520...

Impact of Cytosine 5-Halogens on the Interaction of DNA with Restriction Endonuc...
Votes:7 Comments:0
Impact of Cytosine 5-Halogens on the Interaction of DNA with Restriction Endonucleases and Methyltransferase Received December 2, 2005 Web Release Date: March 24, 2006 Victoria Valinluck, Winni READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/crtoec/2006/19/i04/abs/tx0503...

Microwave Assisted "Click" Chemistry for the Synthesis of Multiple Labeled-Carbo...
Votes:15 Comments:0
Microwave Assisted "Click" Chemistry for the Synthesis of Multiple Labeled-Carbohydrate Oligonucleotides on Solid Support Received March 15, 2006 Web Release Date: May 16, 2006 Camille Bouillon READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/joceah/2006/71/i12/abs/jo0605...

Creating Advanced Multifunctional Biosensors with Surface Enzymatic Transformati...
Votes:28 Comments:0
Creating Advanced Multifunctional Biosensors with Surface Enzymatic Transformations Received January 23, 2006 In Final Form: March 1, 2006 Web Release Date: April 4, 2006 Hye Jin Lee, Alastair READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/langd5/2006/22/i12/abs/la0602...

Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF M...
Votes:4 Comments:0
Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF Mass Spectrometry Received February 22, 2006 Web Release Date: May 4, 2006 Jens Brunner and Jacqueline K. Barton* READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2006/128/i21/abs/ja061...

Site-Specific Cleavage of RNA by a Metal-Free Artificial Nuclease Attached to An...
Votes:37 Comments:0
Site-Specific Cleavage of RNA by a Metal-Free Artificial Nuclease Attached to Antisense Oligonucleotides Received February 13, 2006 Web Release Date: May 25, 2006 Claudio Gnaccarini, Sascha Pete READ MORE
http://pubs.acs.org/cgi-bin/asap.cgi/jacsat/asap/html/ja061036f.html

Synthesis of Building Blocks for Solid-Phase Introduction of Diethylenetriaminep...
Votes:40 Comments:0
Synthesis of Building Blocks for Solid-Phase Introduction of Diethylenetriaminepentaacetic Acid (DTPA) to Oligonucleotides and Oligopeptides Received December 29, 2005 Revised February 13, 2006 W READ MORE
http://pubs.acs.org/cgi-bin/article.cgi/bcches/2006/17/i03/html/bc0503...

Polycefin, a New Prototype of a Multifunctional Nanoconjugate Based on Poly(-L-m...
Votes:16 Comments:0
Polycefin, a New Prototype of a Multifunctional Nanoconjugate Based on Poly(-L-malic acid) for Drug Delivery Received August 11, 2005 Revised December 5, 2005 Web Release Date: January 19, 2006 READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/bcches/2006/17/i02/abs/bc0502...

Synthesis of Oligonucleotides with 3'-Terminal 5-(3-Acylamidopropargyl)-3'-amino...
Votes:13 Comments:0
Synthesis of Oligonucleotides with 3'-Terminal 5-(3-Acylamidopropargyl)-3'-amino-2',3'-dideoxyuridine Residues and Their Reactivity in Single-Nucleotide Steps of Chemical Replication Received Octob READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/joceah/2006/71/i03/abs/jo0520...

Protein Oligomerization Through Domain Swapping: Role of Inter-molecular Interac...
Votes:40 Comments:0
Protein Oligomerization Through Domain Swapping: Role of Inter-molecular Interactions and Protein Concentration 9 September 2005 Sichun Yang, Herbert Levine and Jos? N. Onuchic Journal of Molecul READ MORE
http://www.sciencedirect.com/science...

Oligos Enable New Classes of Therapeutics
Votes:38 Comments:0
Oligos Enable New Classes of Therapeutics 2006 Gail Dutton GEN Updates in Biotechnology Replicor is developing a broad-spectrum, oligonucleotide-based antiviral compound that has potential as a pr READ MORE
http://www.genengnews.com/oligo/oligo_supp_01.aspx

Oligo Manufacturing Puts Emphasis on RNA
Votes:14 Comments:0
Oligo Manufacturing Puts Emphasis on RNA June 1, 2005 Vicki Glaser GEN Updates in Biotechnology As more experimental DNA drugs move through the clinic and into large-scale trials, the demand for READ MORE
http://www.genengnews.com/oligo/oligo_supp_02.aspx

In-Process and Final Product QC for Oligonucleotides
Votes:27 Comments:0
In-Process and Final Product QC for Oligonucleotides 2006 Trey Martin GEN Updates in Biotechnology Recently, in-process and final QC for oligonucleotides have become a selling point in the industr READ MORE
http://www.genengnews.com/oligo/oligo_supp_03.aspx

Design and evaluation of 16S rRNA sequence based oligonucleotide probes for the ...
Votes:17 Comments:0
Design and evaluation of 16S rRNA sequence based oligonucleotide probes for the detection and quantification of Comamonas testosteroniin mixed microbial communities 13 June 2006 BMC Microbiology 2 READ MORE
http://www.biomedcentral.com/1471-2180/6/54/abstract

New mosaic subgenotype of varicella-zoster virus in the USA: VZV detection and g...
Votes:23 Comments:0
New mosaic subgenotype of varicella-zoster virus in the USA: VZV detection and genotyping by oligonucleotide-microarray September 2006 Nikolay Sergeevb, Elena Rubtcovaa, Vladimir Chizikovc, D. Sco READ MORE
http://www.sciencedirect.com/science...

Expression analysis of sex-specific and 17?-estradiol-responsive genes in the Ja...
Votes:36 Comments:0
Expression analysis of sex-specific and 17?-estradiol-responsive genes in the Japanese medaka, Oryzias latipes, using oligonucleotide microarrays August 2006 Katsuyuki Kishia, Emiko Kitagawab, Nor READ MORE
http://www.sciencedirect.com/science...

Efficient and Persistent Splice Switching by Systemically Delivered LNA Oligonuc...
Votes:31 Comments:0
Efficient and Persistent Splice Switching by Systemically Delivered LNA Oligonucleotides in Mice 2006 Jennifer Roberts1, Enzo Palma2, Peter Sazani3, Henrik ?rum4, Moo Cho2 and Ryszard Kole Molecu READ MORE
http://www.sciencedirect.com/science...

Phosphoramidites and solid supports based on N-substituted 2,4-dihydroxybutyrami...
Votes:26 Comments:0
Phosphoramidites and solid supports based on N-substituted 2,4-dihydroxybutyramides: universal reagents for synthesis of modified oligonucleotides 17 July 2006 Natalia N. Dioubankovaa, Andrei D. M READ MORE
http://www.sciencedirect.com/science...

Sub-attomole oligonucleotide and p53 cDNA determinations via a high-resolution s...
Votes:20 Comments:0
Sub-attomole oligonucleotide and p53 cDNA determinations via a high-resolution surface plasmon resonance combined with oligonucleotide-capped gold nanoparticle signal amplification 15 July 2006 Xi READ MORE
http://www.sciencedirect.com/science...

Improved targeting of miRNA with antisense oligonucleotides
Votes:34 Comments:0
Improved targeting of miRNA with antisense oligonucleotides Published online 11 May 2006 Scott Davis, Bridget Lollo, Susan Freier and Christine Esau Nucleic Acids Research MicroRNAs (miRNAs) are READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/8/2294...

Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP...
Votes:10 Comments:0
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides Published online 5 April 2006 Maria Duca1,2,3,4, Domin READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/6/1900...

Synthesis and characterization of oligonucleotides containing 2'-fluorinated thy...
Votes:23 Comments:0
Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction Published online 17 March 2006 Yusuke Doi1, Atsushi Kat READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/5/1540...

Growth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming...
Votes:37 Comments:0
Growth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cells Published online 30 January 2006 Sara Napoli, Um READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/2/734...

BAC to the future! or oligonucleotides: a perspective for micro array comparativ...
Votes:31 Comments:0
BAC to the future! or oligonucleotides: a perspective for micro array comparative genomic hybridization (array CGH) Published online 26 January 2006 Bauke Ylstra*, Paul van den IJssel, Beatriz Car READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/2/445...

Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
Votes:7 Comments:0
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides Published online 24 January 2006 Robert J. Fisher*, Matthew J. Fivash1, Andrew G. Stephen, Nathan A. Hagan2, Shilpa R. Shen READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/2/472...

2'-Deoxy-2'-fluoro-?-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (...
Votes:20 Comments:0
2'-Deoxy-2'-fluoro-?-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing Published online 18 January 2006 A. Kalota, L. Karabon, READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/2/451...

AOBase: a database for antisense oligonucleotides selection and design
Votes:34 Comments:0
AOBase: a database for antisense oligonucleotides selection and design 2006 Xiaochen Bo, Shaoke Lou, Daochun Sun, Jing Yang and Shengqi Wang Nucleic Acids Research 2006 Antisense oligonucleotide READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/suppl_1/D664...

Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2-...
Votes:29 Comments:0
Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2--C-hydroxymethyl-?-D-ribofuranosyl)thymine (2'--hm-dT) Published online 23 December 2005 Chang Geng Peng and Masad J READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/22/7019...

Crystal structures of complexes between aminoglycosides and decoding A site olig...
Votes:23 Comments:0
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding Published READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/17/5677...

Electrochemically directed synthesis of oligonucleotides for DNA microarray fabr...
Votes:18 Comments:0
Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication Published online 5 August 2005 Ryan D. Egeland1,2,* and Edwin M. Southern Nucleic Acids Research 2005 We d READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/14/e125...

Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-formi...
Votes:32 Comments:0
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities Published online 27 July 2005 READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/13/4223...

Genome-wide selection of unique and valid oligonucleotides
Votes:26 Comments:0
Genome-wide selection of unique and valid oligonucleotides Published online 26 July 2005 Heikki Hyyr?, Martti Juhola and Mauno Vihinen Nucleic Acids Research 2005 Functional genomics methods are READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/13/e115...

Stable transmission of targeted gene modification using single-stranded oligonuc...
Votes:21 Comments:0
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs Published online 7 July 2005 Charlotte Andrieu-Soler1, Mariana Casas2, Anne-Marie Faussa READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/12/3733...

Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic p...
Votes:35 Comments:0
Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugs Published online 21 June 2005 Andrzej Grajkowski, Joao Pedras-Vasconcelos1, Vivian Wang1, Cristina Aus?n, So READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/11/3550...

DNA and protein microarray printing on silicon nitride waveguide surfaces
Votes:26 Comments:0
DNA and protein microarray printing on silicon nitride waveguide surfaces Engineering Village 2 2006 Elsevier Inc. Accession number: 8853687 Title: DNA and protein microarray printing on READ MORE
http://www.engineeringvillage2.org/controller/servlet/Controller...

Speeding The Search For Elusive Chromosomal Errors
Votes:16 Comments:0
Speeding The Search For Elusive Chromosomal Errors 6/13/2006 Bioresearch Online High-resolution genomic microarrays allow rapid diagnosis of birth defects in children A pediatric research team READ MORE
http://www.bioresearchonline.com/content/news/article.asp...

Cationic Oligonucleotide-Peptide Conjugates with Aggregating Properties Enter Ef...
Votes:31 Comments:0
Cationic Oligonucleotide-Peptide Conjugates with Aggregating Properties Enter Efficiently into Cells while Maintaining Hybridization Properties and Enzymatic Recognition 2006 Fraley AW; Pons B; Da READ MORE
http://www.medscape.com/medline/abstract/16910671...

Oligonucleotide-based therapeutic options against hepatitis C virus infection
Votes:40 Comments:0
Oligonucleotide-based therapeutic options against hepatitis C virus infection 2006 Trepanier JB, Tanner JE, Alfieri C. Antivir Ther. The hepatitis C virus (HCV) is the cause of a silent pandemic READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antisense oligonucleotide therapy for neurodegenerative disease
Votes:37 Comments:0
Antisense oligonucleotide therapy for neurodegenerative disease 2006 Aug Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Cellular uptake of phosphorothioate oligonucleotide facilitated by cationic porp...
Votes:8 Comments:0
Cellular uptake of phosphorothioate oligonucleotide facilitated by cationic porphyrin: a microfluorescence study 2006 Jul Kocisova E, Praus P, Mojzes P, Sureau F, Stepanek J, Seksek O, Turpin PY. READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression i...
Votes:21 Comments:0
Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression in a Ewing's sarcoma model 2006 Summer Toub N, Bertrand JR, Malvy C, Fattal E, Couvreur P. Oligonucleotides. The cy READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Mucosal immunization against hepatitis A: antibody responses are enhanced by co-...
Votes:35 Comments:0
Mucosal immunization against hepatitis A: antibody responses are enhanced by co-administration of synthetic oligodeoxynucleotides and a novel cationic lipid 2006 Jun 19 Mitchell LA, Joseph A, Keda READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Sequence-specific, electronic detection of oligonucleotides in blood, soil, and ...
Votes:21 Comments:0
Sequence-specific, electronic detection of oligonucleotides in blood, soil, and foodstuffs with the reagentless, reusable E-DNA sensor Engineering Village 2 2006 Elsevier Inc. Accession number: READ MORE
http://www.engineeringvillage2.org

Multifunctional regulators of cell growth are differentially expressed in anergi...
Votes:31 Comments:0
Multifunctional regulators of cell growth are differentially expressed in anergic murine B cells Received 13 May 2006; revised 5 June 2006; accepted 8 June 2006. Available online 4 August 2006. READ MORE
http://www.sciencedirect.com/science...

Application of Elimination Voltammetry to the Resolution of Adenine and Cytosine...
Votes:37 Comments:0
Application of Elimination Voltammetry to the Resolution of Adenine and Cytosine Signals in Oligonucleotides II. Hetero-Oligodeoxynucleotides with Different Sequences of Adenine and Cytosine Nucleot READ MORE
http://www3.interscience.wiley.com/cgi-bin/abstract/112475806/ABSTRACT

Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRN...
Votes:40 Comments:0
Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRNA: chemistry and cell delivery 2006 Mar Turner JJ, Fabani M, Arzumanov AA, Ivanova G, Gait MJ. Medical Research Co READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Conjugates of oligonucleotides and analogues with cell penetrating peptides as g...
Votes:34 Comments:0
Conjugates of oligonucleotides and analogues with cell penetrating peptides as gene silencing agents 2005 Zatsepin TS, Turner JJ, Oretskaya TS, Gait MJ. Department of Chemistry, M.V. Lomonosov M READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Oligonucleotide therapeutics - an emerging novel class of compounds
Votes:13 Comments:0
Oligonucleotide therapeutics - an emerging novel class of compounds 2006 Sep Wacheck V. Abteilung fur Experimentelle Onkologie/Molekulare Pharmakologie, Universitatsklinik fur Klinische Pharmakol READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

In vivo control of acute lymphoblastic leukemia by immunostimulatory CpG oligonu...
Votes:29 Comments:0
In vivo control of acute lymphoblastic leukemia by immunostimulatory CpG oligonucleotides 2006 Oct 26 Fujii H, Trudeau JD, Teachey D, Fish JD, Grupp SA, Schultz KR, Reid GS. Division of Hematolo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Application of unnatural oligonucleotides to chemical modification of gene expre...
Votes:5 Comments:0
Application of unnatural oligonucleotides to chemical modification of gene expression 2006 Oct 18 Sasaki S, Nagatsugi F. Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Mai READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Identification and quantification of GC-rich oligodeoxynucleotides in tissue ext...
Votes:19 Comments:0
Identification and quantification of GC-rich oligodeoxynucleotides in tissue extracts by capillary gel electrophoresis 2006 Oct 16 Noll BO, Debelak H, Uhlmann E. Coley Pharmaceutical GmbH, Elisa READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Building oligonucleotide therapeutics using non-natural chemistries
Votes:33 Comments:0
Building oligonucleotide therapeutics using non-natural chemistries 2006 Oct 13 Wilson C, Keefe AD. Archemix Corp., 300 Third Street, Cambridge, MA 02142, USA Curr Opin Chem Biol. Modified nu READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Nanotechnologies in protein delivery
Votes:27 Comments:0
Nanotechnologies in protein delivery 2006 Sep-Oct Salmaso S, Bersani S, Semenzato A, Caliceti P. Department of Pharmaceutical Sciences, University of Padua, Via F Marzolo, 5-35131 Padua, Italy READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antinociceptive effect of antisense oligonucleotides against the vanilloid recep...
Votes:3 Comments:0
Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1 2006 Oct 11 Christoph T, Gillen C, Mika J, Grunweller A, Schafer MK, Schiene K, Frank R, Jostock R, Ba READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The potential of oligonucleotides for therapeutic applications
Votes:35 Comments:0
The potential of oligonucleotides for therapeutic applications 2006 Oct 11 Fichou Y, Ferec C. Inserm U613, Universite de Bretagne Occidentale, 46 rue Felix Le Dantec, 29275 Brest Cedex, France READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Functionalized nanocomposite coating of a glass surface for oligonucleotide immo...
Votes:11 Comments:0
Functionalized nanocomposite coating of a glass surface for oligonucleotide immobilization 2006 Sep-Oct No authors listed Bioorg Khim. A new type of coating for manufacturing DNA chips was const READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Oligonucleotide therapeutics - an emerging novel class of compounds
Votes:6 Comments:0
Oligonucleotide therapeutics - an emerging novel class of compounds 2006 Sep Wacheck V. Wien Med Wochenschr. Oligonucleotide therapeutics are short, single- or double-stranded DNA or RNA molecu READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Solution structure of a purine rich hexaloop hairpin belonging to PGY/MDR1 mRNA ...
Votes:38 Comments:0
Solution structure of a purine rich hexaloop hairpin belonging to PGY/MDR1 mRNA and targeted by antisense oligonucleotides 2006 Oct 13 Joli F, Bouchemal N, Laigle A, Hartmann B, Hantz E. Laborat READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Rational design and rapid screening of antisense oligonucleotides for prokaryoti...
Votes:33 Comments:0
Rational design and rapid screening of antisense oligonucleotides for prokaryotic gene modulation 2006 Oct 11 Shao Y, Wu Y, Chan CY, McDonough K, Ding Y. Wadsworth Center, New York State Departm READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Electrical manipulation of oligonucleotides grafted to charged surfaces
Votes:28 Comments:0
Electrical manipulation of oligonucleotides grafted to charged surfaces 2006 Sep 21 Rant U, Arinaga K, Fujita S, Yokoyama N, Abstreiter G, Tornow M. Walter Schottky Institute, Technical Universi READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: fro...
Votes:3 Comments:0
Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication 2006 Oct 21 Bellon S, Gasparutto D, Saint-Pierre C, Cadet J. READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Inhibition of iridovirus protein synthesis and virus replication by antisense mo...
Votes:17 Comments:0
Inhibition of iridovirus protein synthesis and virus replication by antisense morpholino oligonucleotides targeted to the major capsid protein, the 18 kDa immediate-early protein, and a viral homolo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Assessing incomplete deprotection of microarray oligonucleotides in situ
Votes:12 Comments:0
Assessing incomplete deprotection of microarray oligonucleotides in situ 2006 Oct 4 Dressman HK, Barley-Maloney L, Rowlette LL, Agris PF, Garcia-Blanco MA. Center for Genome Technology, Institut READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Distance-dependent emission from dye-labeled oligonucleotides on striped au/ag n...
Votes:25 Comments:0
Distance-dependent emission from dye-labeled oligonucleotides on striped au/ag nanowires: effect of secondary structure and hybridization efficiency 2006 Oct 11 Stoermer RL, Keating CD. Departme READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antisense oligonucleotide-induced exon skipping restores dystrophin expression i...
Votes:10 Comments:0
Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD May 26, 2006 G McClorey, H M Moulton P L Iversen, S Fletcher and S D Wilton Gene T READ MORE
http://www.nature.com/gt/journal/v13/n19/abs/3302800a.html

Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and V...
Votes:5 Comments:0
Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development February 15, 2006 Erich Koller, Stephan READ MORE
http://cancerres.aacrjournals.org/cgi/content/abstract/66/4/2059

Market Increases Oligonucleotide Demands
Votes:18 Comments:0
Market Increases Oligonucleotide Demands April 15, 2006 Vicki Glaser Genetic Engineering News Even as new players join the competitive market for research- and pharmaceutical-grade oligonucleoti READ MORE
http://www.genengnews.com/articles/chitem.aspx...

Facilitating the Manufacturing of Oligos
Votes:32 Comments:0
Facilitating the Manufacturing of Oligos August 1, 2006 Carol Potera Genetic Engineering News The approval of Macugen for the treatment of age-related macular degeneration by the FDA in December READ MORE
http://www.genengnews.com/articles/chitem.aspx...

Mouse genomic representational oligonucleotide microarray analysis: Detection of...
Votes:27 Comments:0
Mouse genomic representational oligonucleotide microarray analysis: Detection of copy number variations in normal and tumor specimens July 14, 2006 B. Lakshmi, Ira M. Hall*, Christopher Egan, Joan READ MORE
http://www.pnas.org/cgi/content/abstract/103/30/11234

Global Market for DNA Oligos Tops $700 Million Annually
Votes:21 Comments:0
Global Market for DNA Oligos Tops $700 Million Annually September 6, 2006 Bioinformatics Global Market for DNA Oligos Tops $700 Million Annually ARLINGTON, VA -- September 6, 2006 -- According t READ MORE
http://www.gene2drug.com/reports/default.asp...

Binding of Aminoglycosidic Antibiotics to the Oligonucleotide A-Site Model and 3...
Votes:16 Comments:0
Binding of Aminoglycosidic Antibiotics to the Oligonucleotide A-Site Model and 30S Ribosomal Subunit: Poisson-Boltzmann Model, Thermal Denaturation, and Fluorescence Studies August 8, 2006 Grace Y READ MORE
http://pubs.acs.org/cgi-bin/abstract.cgi/jmcmar/2006/49/i18/abs/jm0602...

Potent Antiscrapie Activities of Degenerate Phosphorothioate Oligonucleotides
Votes:10 Comments:0
Potent Antiscrapie Activities of Degenerate Phosphorothioate Oligonucleotides March 2006 David A. Kocisko,, Andrew Vaillant,, Kil Sun Lee,1 Kevin M. Arnold, Nadine Bertholet, Richard E. Race, Emi READ MORE
http://aac.asm.org/cgi/content/abstract/50/3/1034

An open-access long oligonucleotide microarray resource for analysis of the huma...
Votes:5 Comments:0
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes July 19, 2006 K?vin Le Brigand Roslin Russell, Chim?ne Moreilhon, Jean-Marie Rouillard, B READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/12/e87

Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromoso...
Votes:19 Comments:0
Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromosomal aberrations in 80% of CLL patients: a study of 132 CLL cases with correlation to FISH, IgVH status, and CD38 expr READ MORE
http://www.bloodjournal.org/cgi/content/abstract/108/9/3152

Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleo...
Votes:32 Comments:0
Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleotide Conjugates January 2006 Paola B. Arimondo, Craig J. Thomas,Kahina Oussedik, Brigitte Baldeyrou,Christine Mahieu READ MORE
http://mcb.asm.org/cgi/content/abstract/26/1/324

Mprobe 2.0: Computer-Aided Probe Design for Oligonucleotide Microarray
Votes:8 Comments:0
Mprobe 2.0: Computer-Aided Probe Design for Oligonucleotide Microarray 2006 Li, Wuju; Ying, Xiaomin ingentaconnect Abstract: DNA chips have proven to be effective tools in detecting gene expre READ MORE
http://www.ingentaconnect.com/content/adis/abi/2006/00000005/00000003/...

Adsorption models of hybridization and post-hybridization behaviour on oligonucl...
Votes:16 Comments:0
Adsorption models of hybridization and post-hybridization behaviour on oligonucleotide microarrays 14 June 2006 Conrad J Burden, Yvonne Pittelkow and Susan R Wilson Journal of Physics: Condensed READ MORE
http://www.iop.org/EJ/S/3/743/2J5HXEPO7eOOrsM0yK9SOA/abstract/0953-898...

pH-Dependent mismatch discrimination of oligonucleotide duplexes containing 2'-d...
Votes:18 Comments:0
pH-Dependent mismatch discrimination of oligonucleotide duplexes containing 2'-deoxytubercidin and 2- or 7-substituted derivatives: protonated base pairs formed between 7-deazapurines and cytosine READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/20/5987

Transcription factor decoy oligonucleotides modified with locked nucleic acids: ...
Votes:35 Comments:0
Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity 29 March 2004 Rita Crinelli, Marzia Bianchi, Lucia READ MORE
http://nar.oxfordjournals.org/cgi/content/full/32/6/1874...

Submicron patterning of DNA oligonucleotides on silicon
Votes:18 Comments:0
Submicron patterning of DNA oligonucleotides on silicon 16 August 2004 H. B. Yin, T. Brown, J. S. Wilkinson, R. W. Eason and T. Melvin Nucleic Acids Research The covalent attachment of DNA oligo READ MORE
http://nar.oxfordjournals.org/cgi/content/full/32/14/e118...

Synthesis of fluorescent cyclic cytosine nucleosides and their fluorescent prope...
Votes:37 Comments:0
Synthesis of fluorescent cyclic cytosine nucleosides and their fluorescent properties upon incorporation into oligonucleotides 2006 Masahiro Mizuta3, Kenichi Miyata1,3, Kohji Seio2,3, Tomofumi San READ MORE
http://nass.oxfordjournals.org/cgi/content/abstract/50/1/19

Structure analysis of oligonucleotide in organic solvent
Votes:7 Comments:0
Structure analysis of oligonucleotide in organic solvent 2006 Hiroshi Abe, Naoko Abe and Yoshihiro Ito Nanomedical Engineering Laboratory, Discovery Research Institure, Riken, 2-1 Hirosawa, Wako READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/25

Sugar modification as a means to increase the biological performance of oligonuc...
Votes:37 Comments:0
Sugar modification as a means to increase the biological performance of oligonucleotides 2006 Christian J. Leumann Department of Chemistry & Biochemistry, University of Bern, Freiestrasse 3, CH- READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/55

Synthesis and cross-linking activities of oligodeoxynucleotides containing a 4-o...
Votes:13 Comments:0
Synthesis and cross-linking activities of oligodeoxynucleotides containing a 4-oxoalkenal group 2006 Akio Kobori, Takashi Kobuchi, Masato Ikeda and Akira Murakami Department of Biomolecular Engi READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/59

Synthesis of oligonucleotides containing the Dewar valence isomer of the (6?4) p...
Votes:7 Comments:0
Synthesis of oligonucleotides containing the Dewar valence isomer of the (6?4) photoproduct and their application to (6?4) photolyase studies 2006 Junpei Yamamoto1, Kenichi Hitomi1,2, Takeshi Todo READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/61

Synthesis and ribonuclease activity of oligonucleotides with N3-terpyridine?Cu(I...
Votes:5 Comments:0
Synthesis and ribonuclease activity of oligonucleotides with N3-terpyridine?Cu(II)-linked thymine residues 2006 Kazuhiro Hara, Masaya Kitamura and Hideo Inoue Department of Applied and Bioapplie READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/71

Synthesis and properties of double-stranded antisense oligonucleotides connected...
Votes:38 Comments:0
Synthesis and properties of double-stranded antisense oligonucleotides connected with a pentaerythritol linker 2006 Aya Shibata1, Yoshihito Ueno1,2, Akira Matsuda4 and Yukio Kitade1,2,3 1 Facult READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/73

Solid-phase synthesis of stereoregulated oligodeoxyribonucleoside phosphorothioa...
Votes:19 Comments:0
Solid-phase synthesis of stereoregulated oligodeoxyribonucleoside phosphorothioates 2006 Natsuhisa Oka, Mika Yamamoto, Terutoshi Sato and Takeshi Wada Department of Medical Genome Sciences, Grad READ MORE
http://nass.oxfordjournals.org/cgi/reprint/50/1/123
Oligonucleotides - Protein Synthesis
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