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Lyophilization and Protein Formulation
Monoclonal Antibodies - Protein Synthesis

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Mechanisms of Aggregate Formation and Carbohydrate Excipient Stabiliza-tion of L...

Votes:35 Comments:0
Mechanisms of Aggregate Formation and Carbohydrate Excipient Stabiliza-tion of Lyophilized Humanized Monoclonal Antibody Formulations April 2003 James D. Andya1, Chung C. Hsu1, and Steven J. Shire1 READ MORE
http://www.aapspharmsci.org/articles/ps0502/ps050210/ps050210.pdf

Drug Carriers in Medicine and Biology

Votes:38 Comments:0
Volker Schellenberger at Genencor International discussed the use of mAb-enzyme fusion proteins for the activation of anticancer prodrugs within solid tumors. The major issues in this field are immuno READ MORE
http://pubs.acs.org/cgi-bin/sample.cgi/mpohbp/2004/1/i06/html/mp040010...

Anticancer Antibodies

Votes:15 Comments:0
Anticancer Antibodies Posted 04/17/2003 Jeffrey S. Ross, MD, Karen Gray, PhD, Gary S. Gray, PhD, Peter J. Worland, PhD, Mark Rolfe, PhD American Journal of Clinical Pathology Abstract The recen READ MORE
http://www.medscape.com/viewarticle/452193

A Functional Site on the Human TSH Receptor: A Potential Therapeutic Target in G...

Votes:10 Comments:0
A Functional Site on the Human TSH Receptor: A Potential Therapeutic Target in Graves' Disease Posted 11/13/2003 Alan P. Johnstone, Jeremy C. Cridland, Clive R. Da Costa, Stephen S. Nussey, Phili READ MORE
http://www.medscape.com/viewarticle/462810

Development and characterization of rat monoclonal antibodies to denatured mouse...

Votes:4 Comments:0
Development and characterization of rat monoclonal antibodies to denatured mouse angiotensin-converting enzyme 2005 Balyasnikova IV; Metzger R; Sun ZL; Berestetskaya YV; Albrecht RF; Danilov SM T READ MORE
http://www.medscape.com/medline/abstract/15730516...

Production of monoclonal antibodies against Rift Valley fever virus Application ...

Votes:37 Comments:0
Production of monoclonal antibodies against Rift Valley fever virus Application for rapid diagnosis tests (virus detection and ELISA) in human sera 2006 Zaki A; Coudrier D; Yousef AI; Fakeeh M; Bo READ MORE
http://www.medscape.com/medline/abstract/16102851...

Epitope mapping and features of the epitope for monoclonal antibodies inhibiting...

Votes:32 Comments:0
Epitope mapping and features of the epitope for monoclonal antibodies inhibiting enzymatic activity of Helicobacter pylori urease 2004 Fujii R; Morihara F; Oku T; Hifumi E; Uda T Fukuyama Medical READ MORE
http://www.medscape.com/medline/abstract/15112296...

Rabbit Monoclonal Antibodies

Votes:26 Comments:0
Rabbit Monoclonal Antibodies 08/24/2005 Sabrina Rossi, MD; Licia Laurino, MD; Alberto Furlanetto, MD; Serena Chinellato; Enrico Orvieto, MD; Fabio Canal, MD; Fabio Facchetti, MD; Angelo P. Dei Tos READ MORE
http://www.medscape.com/viewarticle/510156

Chimpanzee Monoclonal Antibodies Protect Against Anthrax Challenge

Votes:21 Comments:0
Chimpanzee Monoclonal Antibodies Protect Against Anthrax Challenge 2006 By Will Boggs, MD J Infect Dis NEW YORK (Reuters Health) Mar 31 - Chimpanzee monoclonal antibodies against anthrax toxin p READ MORE
http://www.medscape.com/viewarticle/528911

Combination Antibody-Based Therapy Destroys Tumors in Mice

Votes:15 Comments:0
Combination Antibody-Based Therapy Destroys Tumors in Mice 2006 Nat Med NEW YORK (Reuters Health) May 11 - Researchers have shown that combination therapy with monoclonal antibodies that trigger READ MORE
http://www.medscape.com/viewarticle/532180

Monoclonal Antibody Combo Promising Against Rabies

Votes:29 Comments:0
Monoclonal Antibody Combo Promising Against Rabies 2006 J Infect Dis NEW YORK (Reuters Health) Apr 06 - Studies in hamsters show that a combination of two human monoclonal antibodies (MAbs) may o READ MORE
http://www.medscape.com/viewarticle/529295

Investigational Monoclonal Antibody Lowers HIV Load

Votes:5 Comments:0
Investigational Monoclonal Antibody Lowers HIV Load Dec. 19, 2005 By Deborah Mitchell WASHINGTON (Reuters Health) Dec 19 - When given with optimized background antiretroviral therapy, an investig READ MORE
http://www.medscape.com/viewarticle/520049

Medical Treatment of Advanced Renal Cell Carcinoma: Present Options and Future D...

Votes:35 Comments:0
Medical Treatment of Advanced Renal Cell Carcinoma: Present Options and Future Directions June 2006 Francesco M. Boccardo, Pamela Guglielmini and Laura Tacchini European Urology Supplements Abst READ MORE
http://www.sciencedirect.com/science...

Potential adverse events with biologic response modifiers

Votes:11 Comments:0
Potential adverse events with biologic response modifiers 2 May 2006 James S.W. Kong, Suzanne S. Teuber and M. Eric Gershwin Autoimmunity Reviews Abstract In recent years, an explosion of biolo READ MORE
http://www.sciencedirect.com/science...

Bevacizumab combination therapy in heavily pretreated, recurrent cervical cancer

Votes:24 Comments:0
Bevacizumab combination therapy in heavily pretreated, recurrent cervical cancer 2 May 2006 Jason D. Wright, Dana Viviano, Matthew A. Powell, Randall K. Gibb, David G. Mutch, Perry W. Grigsby and READ MORE
http://www.sciencedirect.com/science...

Hormone refractory prostate cancer: Management and advances

Votes:19 Comments:0
Hormone refractory prostate cancer: Management and advances April 2006 Guru Sonpavde, Thomas E. Hutson and William R. Berry Cancer Treatment Reviews Summary Effective therapeutic options have n READ MORE
http://www.sciencedirect.com/science...

What have we learned in dermatology from the biologic therapies?

Votes:14 Comments:0
What have we learned in dermatology from the biologic therapies? March 2006 Brian J. Nickoloff and Seth R. Stevens Journal of the American Academy of Dermatology Abstract Recent advances in our READ MORE
http://www.sciencedirect.com/science...

Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies

Votes:8 Comments:0
Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies 15 February 2006 Guo-Zhong Tao, Ikuo Nakamichi, Nam-On Ku, Jing Wang, Maria Frolkis, Xiaosong Gong, Weimin Zhu, Rober READ MORE
http://www.sciencedirect.com/science...

Monoclonal antibodies and fusion proteins in medicine

Votes:3 Comments:0
Monoclonal antibodies and fusion proteins in medicine October 2005 Stamatis-Nick C. Liossis and George C. Tsokos Journal of Allergy and Clinical Immunology Abstract Humanized antibodies and dec READ MORE
http://www.sciencedirect.com/science...

Validation of immunoassays used to assess immunogenicity to therapeutic monoclon...

Votes:35 Comments:0
Validation of immunoassays used to assess immunogenicity to therapeutic monoclonal antibodies 15 September 2005 Dong Geng, Gopi Shankar, Allen Schantz, Manoj Rajadhyaksha, Hugh Davis and Carrie Wa READ MORE
http://www.sciencedirect.com/science...

Application of monoclonal antibody immobilized polyurethane film for site-specif...

Votes:24 Comments:0
Application of monoclonal antibody immobilized polyurethane film for site-specific gene therapy 2006 Jun Zhang LH, Song CX, Wang MY, Yang J, Tang LN. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. OBJECT READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Multiple myeloma: Monoclonal antibodies-based immunotherapeutic strategies and t...

Votes:19 Comments:0
Multiple myeloma: Monoclonal antibodies-based immunotherapeutic strategies and targeted radiotherapy 2006 Jul Chatterjee M, Chakraborty T, Tassone P. Eur J Cancer. Multiple myeloma (MM) is an i READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Monoclonal antibody HCV-Ab(XTL)68 in patients undergoing liver transplantation f...

Votes:13 Comments:0
Monoclonal antibody HCV-Ab(XTL)68 in patients undergoing liver transplantation for HCV: Results of a phase 2 randomized study 2006 Aug 24 Schiano TD, Charlton M, Younossi Z, Galun E, Pruett T, Tur READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Human monoclonal antibodies to domain C of tenascin-C selectively target solid t...

Votes:8 Comments:0
Human monoclonal antibodies to domain C of tenascin-C selectively target solid tumors in vivo 2006 Aug 22 Silacci M, Brack SS, Spath N, Buck A, Hillinger S, Arni S, Weder W, Zardi L, Neri D. Pro READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The Future of Monoclonal Antibodies Therapeutics: New Publication Announcement f...

Votes:3 Comments:0
The Future of Monoclonal Antibodies Therapeutics: New Publication Announcement from Piribo (PRWEB) August 23, 2006 -- The monoclonal antibody (mAb) market has grown rapidly in recent years, reachin READ MORE
http://www.prweb.com/releases/2006/8/prweb427237.htm

Characterization of Anti-TIMP-1 Monoclonal Antibodies for Immunohistochemical Lo...

Votes:30 Comments:0
Characterization of Anti-TIMP-1 Monoclonal Antibodies for Immunohistochemical Localization in Formalin-fixed, Paraffin-embedded Tissue 2006 Irene Vejgaard Sorensen, Claus Fenger, Henrik Winther, N READ MORE
http://www.jhc.org/cgi/content/abstract/54/10/1075

Comparison of intratumoral bolus injection and convection-enhanced delivery of r...

Votes:25 Comments:0
Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies 2006 Apr 15 Sampson JH, Akabani G, Friedman AH, Bigner D, Kunwar S, B READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

FGF-1 as a possible carrier for targeted drug delivery

Votes:39 Comments:0
FGF-1 as a possible carrier for targeted drug delivery 2006 Marcinkowska E, Superat K, Wiedlocha A. Oncol Res. Delivery of anticancer chemotherapeuticals to tumor cells raises many problems due READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Endovascular microcoil applied for gene delivery system

Votes:14 Comments:0
Endovascular microcoil applied for gene delivery system 2005 Apr Mei L, Sun HF, Tang LN, Yang J, Chang J, Song CX. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. OBJECTIVE: To explore the possibility of READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Administration of antibody to the lung protects mice against pneumonic plague

Votes:9 Comments:0
Administration of antibody to the lung protects mice against pneumonic plague 2006 May Hill J, Eyles JE, Elvin SJ, Healey GD, Lukaszewski RA, Titball RW. Infect Immun. Intratracheal delivery of READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

AbMiner: A bioinformatic resource on available monoclonal antibodies and corresp...

Votes:4 Comments:0
AbMiner: A bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies 6 April 2006 Sylvia M Major1 ,4 , Satoshi READ MORE
http://www.biomedcentral.com/1471-2105/7/192

Monoclonal antibody combinations in CLL: evolving strategies

Votes:37 Comments:0
Monoclonal antibody combinations in CLL: evolving strategies Available online 22 September 2006. Stefan Faderl MD, a, , Associate Professor, Susan O'Brien MDa, Professor and Michael J. Keating MB READ MORE
http://www.sciencedirect.com/science...

Monoclonal Antibody Reduces Exacerbations In Asthmatics, Study Finds

Votes:9 Comments:0
Monoclonal Antibody Reduces Exacerbations In Asthmatics, Study Finds October 10, 2006 Science Daily Patients with symptomatic moderate asthma who were treated with anti-tumor necrosis factor alp READ MORE
http://www.sciencedaily.com/releases/2006/10/061002063856.htm

Development of human monoclonal antibodies against diseases caused by emerging a...

Votes:4 Comments:0
Development of human monoclonal antibodies against diseases caused by emerging and biodefense-related viruses. Zhu Z, Dimitrov AS, Chakraborti S, Dimitrova D, Xiao X, Broder CC, Dimitrov DS. Febru READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Potent Neutralization of Hendra and Nipah Viruses by Human Monoclonal Antibodies

Votes:17 Comments:0
Potent Neutralization of Hendra and Nipah Viruses by Human Monoclonal Antibodies January 2006 Zhongyu Zhu, Antony S. Dimitrov, Katharine N. Bossart, Gary Crameri,Kimberly A. Bishop, Vidita Choudhr READ MORE
http://www.pubmedcentral.nih.gov/articlerender.fcgi...

The Making of a Monoclonal Antibody

Votes:31 Comments:0
The Making of a Monoclonal Antibody June 13, 2006 By Sharon Reynolds NCI Cancer Bulletin n cancer treatment today, three letters have infiltrated the oncology dialect: "mab," as in bevacizumab ( READ MORE
http://www.cancer.gov/ncicancerbulletin/NCI_Cancer_Bulletin_061306/pag...

Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412

Votes:6 Comments:0
Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412 September 7, 2006 Ganesh Suntharalingam, F.R.C.A., Meghan R. Perry, M.R.C.P., Stephen Ward, F.R.C.A., Stephen J. Bre READ MORE
https://content.nejm.org/cgi/content/full/355/10/1018

New drug brings relief to carcinoma patients

Votes:39 Comments:0
New drug brings relief to carcinoma patients September 20, 2006 Biopeer Epithelial cancers, also called carcinomas, are the most widespread of all cancers. Carcinomas account for about 85 per cen READ MORE
http://www.biopeer.com/biopeer/monoclonal_antibodies/index.html

Characterization of a monoclonal antibody with specificity for holo-transcobalam...

Votes:34 Comments:0
Characterization of a monoclonal antibody with specificity for holo-transcobalamin January 4, 2006 Lars Orning , Anne Rian , Andrew Campbel , Jeff Brady , Sergey N Fedosov , Birgit Bramlage , Ke READ MORE
http://www.nutritionandmetabolism.com/content/3/1/3

Targeted therapies in solid tumors: Monoclonal antibodies and small molecules

Votes:23 Comments:0
Targeted therapies in solid tumors: Monoclonal antibodies and small molecules 2006 Weiner LM, Borghaei H. Hum Antibodies. The considerable progress in our understanding of the complex cellular READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

A rapid and efficient method for generating anti-variable region monoclonal anti...

Votes:36 Comments:0
A rapid and efficient method for generating anti-variable region monoclonal antibodies using type-1 interferons as immune modulators 2006 Staquet K, Fisher J, Lamb R, Bannish G, Duchala C, Mbow M READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The new era in the treatment of advanced colorectal cancer patients: the role of...

Votes:12 Comments:0
The new era in the treatment of advanced colorectal cancer patients: the role of monoclonal antibodies 2006 Nov Vincenzi B, Schiavon G, Silletta M, Santini D, Tonini G. University Campus Bio-Med READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Preparation of monoclonal antibodies against human mesenchymal stem cells

Votes:25 Comments:0
Preparation of monoclonal antibodies against human mesenchymal stem cells 2006 Sep Liao ZX, Shen JG, Lai XY, Huang H. Institute of Immunology, College of Medicine, Zhejiang University, Hangzhou READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Marburgvirus nucleoprotein-capture enzyme-linked immunosorbent assay using monoc...

Votes:20 Comments:0
Marburgvirus nucleoprotein-capture enzyme-linked immunosorbent assay using monoclonal antibodies to recombinant nucleoprotein: detection of authentic marburgvirus 2006 Oct Saijo M, Georges-Courbot READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Protective and immunochemical activities of monoclonal antibodies reactive with ...

Votes:15 Comments:0
Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule 2006 Oct 23 Kozel TR, Thorkildson P, Brandt S, Welch WH, Lovchik JA, Auco READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Infectious complications related to nucleoside analogs and monoclonal antibodies

Votes:9 Comments:0
Infectious complications related to nucleoside analogs and monoclonal antibodies 2006 Oct 27 Maschmeyer G, Haas A. Medizinische Klinik, Abt. Hamatologie und Onkologie, Klinikum Ernst von Bergman READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Recent developments in colorectal cancer treatment by monoclonal antibodies

Votes:4 Comments:0
Recent developments in colorectal cancer treatment by monoclonal antibodies 2006 Nov Arsene D, Galais MP, Bouhier-Leporrier K, Reimund JM. Centre Hospitalier Universitaire de Caen, Service d'Hep READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Downstream processing of monoclonal antibodies-Application of platform approache...

Votes:37 Comments:0
Downstream processing of monoclonal antibodies-Application of platform approaches 2006 Oct 12 Shukla AA, Hubbard B, Tressel T, Guhan S, Low D. Process Development, Amgen Inc., 1201 Amgen Court W READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The antigen binding sites of various hCG monoclonal antibodies show homology to ...

Votes:31 Comments:0
The antigen binding sites of various hCG monoclonal antibodies show homology to different domains of LH receptor 2006 Oct 10 Gadkari RA, Sandhya S, Sowdhamini R, Dighe RR. Molecular Reproduction READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Monoclonal antibodies to mechano-growth factor

Votes:26 Comments:0
Monoclonal antibodies to mechano-growth factor 2006 Oct Kravchenko IV, Furalyov VA, Khotchenkov VP, Popov VO. A.N. Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russia Hy READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Production and Characterization of Monoclonal Antibodies to Chlamydia trachomati...

Votes:39 Comments:0
Production and Characterization of Monoclonal Antibodies to Chlamydia trachomatis 2006 Oct Kumar A, Mittal A. Institute of Pathology-ICMR, Safdarjang Hospital Campus, New Delhi, India Hybridoma READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Antigen-based immunofluorescence analysis of B-cell targeting: advanced technolo...

Votes:34 Comments:0
Antigen-based immunofluorescence analysis of B-cell targeting: advanced technology for the generation of novel monoclonal antibodies with high efficiency and selectivity 2006 Oct Tomita M, Fukuda READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Preparation and Characterization of Four Novel Monoclonal Antibodies Specific to...

Votes:10 Comments:0
Preparation and Characterization of Four Novel Monoclonal Antibodies Specific to N51(L6)C46 Polypeptide Simulating Fusogenic Core Structure of GP41 Subunit of HIV-1 2006 Oct Chen Z, Hong L, Li Z, READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Generation of Monoclonal Antibody Recognized by the GXXXG Motif (Glycine Zipper)...

Votes:23 Comments:0
Generation of Monoclonal Antibody Recognized by the GXXXG Motif (Glycine Zipper) of Prion Protein 2006 Oct Choi JK, Park SJ, Jun YC, Oh JM, Jeong BH, Lee HP, Park SN, Carp RI, Kim YS. Ilsong Ins READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Advances in cancer therapy with radiolabeled monoclonal antibodies

Votes:37 Comments:0
Advances in cancer therapy with radiolabeled monoclonal antibodies 2006 Dec Goldenberg DM, Sharkey RM. Center for Molecular Medicine and Immunology, Garden State Cancer Center, Belleville, NJ, U READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Refractory sweet syndrome with autoimmune organizing pneumonia treated with mono...

Votes:13 Comments:0
Refractory sweet syndrome with autoimmune organizing pneumonia treated with monoclonal antibodies to tumor necrosis factor 2004 Dec Karamlou K, Gorn AH. From the Division of Rheumatology, Depart READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Modulation of hybridoma cell growth and antibody production by coating cell cult...

Votes:6 Comments:0
Modulation of hybridoma cell growth and antibody production by coating cell culture material with extracellular matrix proteins Received 18 May 2006; revised 21 December 2006; accepted 16 January READ MORE
http://www.sciencedirect.com/science...

Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum

Votes:20 Comments:0
Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum Received 21 June 2006; revised 10 October 2006; accepted 22 November 2006. Available online 3 January 2007 Miao READ MORE
http://www.sciencedirect.com/science...

Production and characterization of monoclonal antibodies against different epito...

Votes:15 Comments:0
Production and characterization of monoclonal antibodies against different epitopes of Ebola virus antigens Received 17 October 2006; revised 31 January 2007; accepted 5 February 2007. Available READ MORE
http://www.sciencedirect.com/science...
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