Tween induced technetium-99m isonitrile complex, two-stage isonitrile medicinal box and its use

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Patent number: CN1510036
Publication date: 2004-07-07
Inventor: WANG XUEBIN (CN); TANG ZHIGANG (CN); LU GONGXU (CN)
Applicant: UNIV BEIJING NORMAL (CN)
Classification:
- international: C07F11/00; A61K51/00
- european:
Application number: CN20020158636 20021225
Priority number(s): CN20020158636 20021225
Abstract of CN1510036
A tween (sorbitol polyethoxy oleate) mediated and Tc-99m labeled isonitrile match used as the developer of cardiac muscle and tumor is a compound of tween and Tc-99m-(CNR)6, where R is chosen from the C1-10 alkyl or cycloalkyl. It is prepared by wet method or medicine box method. Said medicine box method contains bottle A which is a freeze dried medicine box containing freeze drying reducer, pH buffering agent and excipient and bottle B which contains the solution of isonitrile ligand and tween. Its advantage is clear and high-quality image.
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