The biological significance of lipid-protein interactions

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The biological significance of lipid-protein interactions
Engineering Village 2
2006 Elsevier Inc.
Accession number: 8992911

Title: The biological significance of lipid-protein interactions

Authors: Findlay, H.E.1 ; Booth, P.J.1

Author affiliation: 1 Dept. of Biochem., Univ. of Bristol, Bristol, UK

Serial title: Journal of Physics: Condensed Matter

Abbreviated serial title: J. Phys., Condens. Matter. (UK)

Volume: 18

Issue: 28

Publication date: 19 July 2006

Pages: S1281-91

Language: English

ISSN: 0953-8984

CODEN: JCOMEL

Document type: Journal article (JA)

Publisher: IOP Publishing

Country of publication: UK

Material Identity Number: M789-2006-029

Abstract: Biological membranes are complex environments, where membrane proteins are surrounded by a bilayer composed of many different types of lipid. The physical properties of the bilayer influence protein structure, folding and function, while specific interactions with lipid molecules can also contribute towards the biological activity of some membrane proteins. Improving understanding of these interactions has resulted in the development of synthetic lipid systems that allow the bilayer properties to be rationally manipulated in vitro to control protein behaviour

Number of references: 68

Inspec controlled terms: biocontrol - biomembranes - lipid bilayers - molecular biophysics - proteins

Uncontrolled terms: biological significance - lipid-protein interactions - biological membranes - membrane proteins - bilayer - lipid - physical properties - protein structure - protein folding - protein function - lipid molecules - biological activity - synthetic lipid systems - bilayer properties - in vitro - protein behaviour control

Inspec classification codes: A8720 Membrane biophysics - A8715 Molecular biophysics

Treatment: Theoretical or Mathematical (THR); Experimental (EXP)

Discipline: Physics (A)

DOI: 10.1088/0953-8984/18/28/S11

Database: Inspec

Copyright 2006, The Institution of Engineering and Technology
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