Spray freeze-dried compositions - Patent Pending

United States Patent Application 20030202978
Kind Code A1
Maa, Yuh-Fun ; et al. October 30, 2003
Spray freeze-dried compositions
Abstract
A process for producing a powder comprises spray freeze-drying an aqueous solution or suspension comprising a pharmaceutical agent, said solution or suspension having a solids content of 20% by weight or more. The spray freeze-dried powder may be administered to a subject via a needleless syringe.
Inventors: Maa, Yuh-Fun; (Fremont, CA) ; Prestrelski, Steven J.; (Fremont, CA) ; Burkoth, Terry L.; (Fremont, CA)
Correspondence Name and Address: Sharon E. Crane, Ph. D.
BURNS, DOANE, SWECKER & MATHIS, L.L.P.
P.O. Box 1404
Alexandria
VA
22313-1404
US
Serial No.: 164594
Series Code: 10
Filed: June 10, 2002
U.S. Current Class: 424/184.1; 424/193.1; 424/195.11; 424/196.11; 424/405; 424/417; 424/418; 424/421; 514/2; 514/44
U.S. Class at Publication: 424/184.1; 424/193.1; 424/195.11; 424/196.11; 514/2; 514/44; 424/405; 424/417; 424/418; 424/421
Intern'l Class: A61K 039/00; A61K 039/38; A61K 039/385; A01N 037/18; A61K 038/00; A61K 031/70; A01N 043/04; A01N 025/00; A01N 025/26; A01N 025/28