Spray-dried alum compositions - Patent Pending

United States Patent Application 20040213798
Kind Code A1
Maa, Yuh-Fun ; et al. October 28, 2004
Spray-dried alum compositions
Abstract
A gel-forming free-flowing powder suitable for use as a vaccine is prepared by spray-drying an aqueous suspension that contains an antigen adsorbed to an aluminum salt adjuvant, a saccharide, an amino acid or a salt thereof, and a colloidal substance. Processes for forming these powder compositions are also described, as well as methods of using the compositions in a vaccination procedure.
Inventors: Maa, Yuh-Fun; (Millbrae, CA) ; Zhao, Lu; (Union City, CA) ; Prestrelski, Steven J.; (Mountain View, CA)
Correspondence Name and Address: FOLEY AND LARDNER
SUITE 500
3000 K STREET NW
WASHINGTON
DC
20007
US
Assignee Name and Adress: PowderJect Vaccines, Inc.
Serial No.: 852740
Series Code: 10
Filed: May 25, 2004
U.S. Current Class: 424/184.1
U.S. Class at Publication: 424/184.1
Intern'l Class: A61K 039/00