STABLE LYOPHILIZED THIOTEPA COMPOSITION - Patent Pending

(12) Patent Application: (11) CA 2135265
ABSTRACT
A stable lyophilized composition of the antitumor alkylating agent thiotepa and a method of preparing such a composition via co-lyophilization of the active ingredient with a pharmaceutical acceptable alkalizing agent.
(72) Inventors (Country): KU, MANNCHING S. (United States)
VELEZ, JORGE (United States)
HOFFMAN, JOE (United States)
ZAMORA, LOURDES (United States)
(73) Owners (Country): WYETH HOLDINGS CORPORATION (United States)
(71) Applicants (Country):
(74) Agent: SMART & BIGGAR
(45) Issued:
(22) Filed: Nov. 7 , 1994
(41) Open to Public Inspection: May 10, 1995
Examination requested: Oct. 10, 2001
(51) International Class (IPC): A61K 47/02
A61K 9/14
A61K 31/675
Patent Cooperation Treaty (PCT): No
(30) Application priority data: Application No. Country Date
08/150,501 United States Nov. 9 , 1993
Availability of licence: N/A
Language of filing: English