SHEET-LIKE COMPOSITION

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SHEET-LIKE COMPOSITION
Publication Number: WO/2007/013331 International Application No.: PCT/JP2006/314245
Publication Date: 01.02.2007 International Filing Date: 19.07.2006

Int. Class.: A61L 27/00 (2006.01), A61F 2/14 (2006.01)
Applicants: ArBlast Co., Ltd. [JP/JP]; Kobe International Business Center Bldg., 5-5-2, Minatojima-minamimachi, Chuo-ku, Kobe-city, Hyogo, 6500047 (JP) (All Except US).
KINOSHITA, Shigeru [JP/JP]; 1-3-11, Kitabatake, Abeno-ku, Osaka-shi, Osaka, 5450035 (JP).
NAKAMURA, Takahiro [JP/JP]; 14-2-611, Yoshidakawaracho, Sakyo-ku, Kyoto-shi, Kyoto, 6068305 (JP) (US Only).
YOKOI, Norihiko [JP/JP]; Room 501, Grand Form Kyoto Karasuma, 251-1, kamie-cho, Kamigoryo, Muromachi-higashiiru, Kuramaguchi-dori, Kita-ku, Kyoto-shi, Kyoto, 6038147 (JP) (US Only).
KURIHARA, Eiji [JP/JP]; c/o ArBlast Co., Ltd., Kobe International Business Center Bldg., 5-5-2, Minatojima-minamimachi, Chuo-ku, Kobe-city, Hyogo, 6500047 (JP) (US Only).
Inventors: KINOSHITA, Shigeru [JP/JP]; 1-3-11, Kitabatake, Abeno-ku, Osaka-shi, Osaka, 5450035 (JP).
NAKAMURA, Takahiro [JP/JP]; 14-2-611, Yoshidakawaracho, Sakyo-ku, Kyoto-shi, Kyoto, 6068305 (JP).
YOKOI, Norihiko [JP/JP]; Room 501, Grand Form Kyoto Karasuma, 251-1, kamie-cho, Kamigoryo, Muromachi-higashiiru, Kuramaguchi-dori, Kita-ku, Kyoto-shi, Kyoto, 6038147 (JP).
KURIHARA, Eiji [JP/JP]; c/o ArBlast Co., Ltd., Kobe International Business Center Bldg., 5-5-2, Minatojima-minamimachi, Chuo-ku, Kobe-city, Hyogo, 6500047 (JP).
Agent: KONISHI, Tomimasa; Marunouchi Estate Bldg., 17-12, Marunouchi 2-chome, Naka-ku, Nagoya-shi, Aichi 460-0002 (JP).
Priority Data: 2005-214339 25.07.2005 JP

Abstract:
Disclosed is a sheet-like composition comprising an amnion which has excellent storage property and handling property and shows a high flexibility during use. An amnion having trehalose added thereto is used. By the addition of trehalose, the amnion is improved in flexibility and the damage of a basement membrane and a stratum compactum in the amnion which may be caused during lyophilization treatment can be prevented.