Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus - Patent Pending

United States Patent Application 20050002965
Kind Code A1
Yun, Chae-Ok ; et al. January 6, 2005
Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus
Abstract
Disclosed is a recombinant adenovirus with a protein containing a VSV-G epitope derived from vesicular stomatitis virus (VSV). Also, the present invention discloses a pharmaceutical composition comprising such a recombinant adenovirus and a pharmaceutically acceptable carrier. Further, the present invention discloses a recombinant plasmid capable of expressing the recombinant adenovirus and a host cell transformed with the recombinant adenovirus.
Inventors: Yun, Chae-Ok; (Seoul, KR) ; Kim, Joo-Hang; (Seoul, KR)
Correspondence Name and Address: HAMILTON, BROOK, SMITH & REYNOLDS, P.C.
530 VIRGINIA ROAD
P.O. BOX 9133
CONCORD
MA
01742-9133
US
Serial No.: 491313
Series Code: 10
Filed: March 29, 2004
PCT Filed: September 28, 2002
PCT NO: PCT/KR02/01831
U.S. Current Class: 424/199.1; 424/93.2; 435/235.1
U.S. Class at Publication: 424/199.1; 424/093.2; 435/235.1
Intern'l Class: C12Q 001/70; A61K 039/12; A61K 048/00; C12N 007/00