RNAI POTENCY PREDICTION METHOD

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RNAI POTENCY PREDICTION METHOD
Publication number: EP1694843
Publication date: 2006-08-30
Inventor: HALL JONATHAN (CH); HUESKEN DIETER (DE); LANGE JOERG BERND (DE); NATT FRANCOIS JEAN-CHARLES (CH); REINHARDT MISCHA WERNER HENRI (FR)
Applicant: NOVARTIS AG (CH); NOVARTIS PHARMA GMBH (AT)
Classification:
- international: C12N15/11; G06F17/50; G06N3/10; G06F19/00; C12N15/11; G06F17/50; G06N3/00; G06F19/00
- european: C12N15/11M
Application number: EP20040820427 20041209
Priority number(s): WO2004EP14037 20041209; US20030528430P 20031210
Abstract not available for EP1694843
Abstract of corresponding document: WO2005059132

Methods for making an algorithm for the prediction of the RNAi potency of a RNAi reagent are provided. Also provided are methods for predicting the RNAi potency of a RNAi reagent and methods for inhibiting the expression of a given target gene using such an algorithm.