RNAI-MEDIATED INHIBITION OF FRIZZLED RELATED PROTEIN-1 FOR TREATMENT OF GLAUCOMA

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RNAI-MEDIATED INHIBITION OF FRIZZLED RELATED PROTEIN-1 FOR TREATMENT OF GLAUCOMA
Publication number: WO2006099353
Publication date: 2006-09-21
Inventor: CLARK ABBOT F (US); WANG WAN-HENG (US); MCNATT LORETTA GRAVES (US); CHATTERTON JON E (US)
Applicant: ALCON INC (CH); CLARK ABBOT F (US); WANG WAN-HENG (US); MCNATT LORETTA GRAVES (US); CHATTERTON JON E (US)
Classification:
- international: C12N15/11; A61K31/713; A61P27/06; C12N15/11; A61K31/713; A61P27/00;
- european: C12N15/11B
Application number: WO2006US09000 20060310
Priority number(s): US20050660556P 20050311; US20050688633P 20050608
Cited documents:

US2004115195
WO2004076639
WO0164949
XP002391011
XP002391173

Abstract of WO2006099353

RNA interference is provided for inhibition of Frizzled Related Protein-1 mRNA expression, in particular, for treating patients having glaucoma or at risk of developing glaucoma.