Pseudorabies TK*/gE*/gI* gene dificiency mark live vaccine and preparation method thereof
Patent number: CN1523103
Publication date: 2004-08-25
Inventor: CHEN HUANCHUN LIU (CN)
Applicant: HUAZHONG AGRICULTURAL UNIVERSI (CN)
Classification:
- international: C12N7/01; A61K39/205; A61P31/20
- european:
Application number: CN20030156706 20030908
Priority number(s): CN20030156706 20030908
Abstract of CN1523103
The present invention discloses a construction of three-gene defected recombinant pseudorabies virus (PrV) strain, vaccine prepared by said strain, method for constructing said strain and method for preparing said vaccine. The described recombinant pseudorabies virus strain defects genes of TK.gE ang gI, and contains no exogenous gene. The described vacine belongs to the freeze-dried live vaccine made up by virus liquid containing said invention and gelatin. Said invented live vaccine can be inoculated on the piglet, slaughter pig and sow with farrow, and can obtain obious immune effect. Said vaccine has good biological safety, and can be used for preventing and curing pseudorabies.
Data supplied from the esp@cenet database - Worldwide
Votes:37
Comments: 0