Powder formulations of rSEB for improved vaccination - Patent Pending

United States Patent Application 20040213745
Kind Code A1
Sullivan, Vincent ; et al. October 28, 2004
Powder formulations of rSEB for improved vaccination
Abstract
A method of preparing a pharmaceutical composition is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles to produce a powder. Compositions made by the above methods, and methods of using the compositions, are also described.
Inventors: Sullivan, Vincent; (Cary, NC) ; Mikszta, John; (Durham, NC) ; Hwang, Robin; (Thousand Oaks, CA) ; Mar, Kevin D.; (Durham, NC) ; Campbell, Robert L.; (Bahama, NC)
Correspondence Name and Address: DAVID W. HIGHET, VP AND CHIEF IP COUNSEL
BECTON, DICKINSON AND COMPANY
1 BECTON DRIVE, MC 110
FRANKLIN LAKES
NJ
07417-1880
US
Serial No.: 783061
Series Code: 10
Filed: February 20, 2004
U.S. Current Class: 424/46
U.S. Class at Publication: 424/046
Intern'l Class: A61L 009/04; A61K 009/14; A61K 009/50