Pleuromutilin derivatives with antimicrobial activity

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United States Patent Application 20050143393
Kind Code A1
Dean, David Kenneth ; et al. June 30, 2005
Pleuromutilin derivatives with antimicrobial activity
Abstract
Pleuromutilin compounds of the formula: 1 are of use in anti-bacterial therapy.
Inventors: Dean, David Kenneth; (Harlow, Essex, GB) ; Naylor, Antoinette; (Harlow Essex, GB) ; Takle, Andrew Kenneth; (Harlow Essex, GB)
Correspondence Name and Address: SMITHKLINE BEECHAM CORPORATION
CORPORATE INTELLECTUAL PROPERTY-US, UW2220
P. O. BOX 1539
KING OF PRUSSIA
PA
19406-0939
US
Serial No.: 416432
Series Code: 10
Filed: October 17, 2003
PCT Filed: November 12, 2001
PCT NO: PCT/GB01/04995
U.S. Current Class: 514/255.01; 514/412; 514/548; 544/380; 560/194
U.S. Class at Publication: 514/255.01; 514/412; 514/548; 544/380; 560/194
Intern'l Class: A61K 031/496; C07D 241/04; C07C 069/34; C07C 069/52