Peptide/lipid complex formation by co-lyophilization

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United States Patent Application 20030099714
Kind Code A1
Dasseux, Jean-Louis May 29, 2003
Abstract
The invention relates to the formation of peptide/lipid vesicles and complexes through the co-lyophilization of peptides, preferably that are able to adopt an amphipathic alphahelical conformation, and one or more lipids. A single solution which solubilizes both the peptides and lipids or two separate solutions may be lyophilized.
Inventors: Dasseux, Jean-Louis; (Mannheim, DE)
Correspondence Name and Address: PENNIE & EDMONDS LLP
1155 Avenue of the Americas
New York
NY
10036-2711
US
Serial No.: 252940
Series Code: 10
Filed: September 23, 2002
U.S. Current Class: 424/489; 426/384; 514/2
U.S. Class at Publication: 424/489; 514/2; 426/384
Intern'l Class: A61K 038/00; A23C 001/06; A61K 009/14
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