Peptide/lipid complex formation by co-lyophilization
Patent Number: US6287590
Publication date: 2001-09-11
Inventor(s): DASSEUX JEAN-LOUIS [DE]
Applicant(s):
Requested Patent: CN1280490
Application Number: US19970942597 19971002
Priority Number(s): US19970942597 19971002
IPC Classification: A61K9/127
EC Classification: A61K9/127M, A61K9/127P, A61K38/17A2, A61K47/48R, C07K14/775
Equivalents: AU749344, AU9671598, CA2305704, DE69822176D, DE69822176T, EP1019025 (WO9917740), A1, B1, ES2217591T, HU0003930, JP2001522781T, NO20001683, NZ503721, PL339654, RU2224506, WO9917740
Abstract
The invention relates to the formation of peptide/lipid vesicles and complexes through the co-lyophilization of peptides, preferably that are able to adopt an amphipathic alphahelical conformation, and one or more lipids. A single solution which solubilizes both the peptides and lipids or two separate solutions may be lyophilized.

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Votes:20