OCULAR IONTOPHORESIS DEVICE FOR DELIVERING SIRNA AND APTAMERS

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OCULAR IONTOPHORESIS DEVICE FOR DELIVERING SIRNA AND APTAMERS
Inventor: ROY PIERRE (FR)
Applicant: EYEGATE PHARMA SA (FR); ROY PIERRE (FR)
EC: A61N1/30B2
IPC: A61N1/30; A61N1/30
Publication info: WO2006072887
Date: 2006-07-13
Abstract of WO2006072887
The invention relates to a device of ocular iontophoresis for delivering active substances, comprising: a reservoir capable of receiving at least one medium containing active substances chosen among interfering RNA (siRNA) and aptamers, the reservoir extending along a surface intended to cover a part of an eyeball; an active electrode associated with the reservoir so as to, when polarized, supply an electric field through the medium to the eye; wherein the area and the shape of the surface of the reservoir are chosen for maximising the distribution of the active substances on an ocular area determinate by the limits of accessibility of the reservoir and the nature of the intraocular tissue to be treated.